Eduardo Villablanca
About me
During my Master degree, I was trained as a developmental biologist, with expertise in cell migration using zebrafish as in vivo model. As a doctoral student in the molecular medicine program at San Raffaele University, Milan, I started my training as immunologist with specific focus on dendritic cells (DC) and tumor cell interaction. I identified a novel immune escape mechanism in which tumors produce and secrete oxysterols, which in turn target LXR receptors inhibiting CCR7 expression in DC (*J. **immunol**, J. Leuko. Biol.* and *Nat. Medicine*). Interested in intestinal leukocyte trafficking, I joined J. Rodrigo Mora’s lab (Massachusetts General Hospital, Boston) to perform my postdoctoral training. During the first two years I contributed to determine the mechanisms by which intestinal DC gain their gut-associated tolerogenic properties (*Gastroenterology*, *J. Immunology, Cell*, etc.).
In 2010, I won the prestigious postdoctoral fellow award from the Crohn’s and Colitis Foundation of America (CCFA) and took the lead of a project aimed to further characterize the mechanisms of oral immunological tolerance induction. I found that expressions of gut homing receptors (e.g. CCR9) are crucial on leukocytes to establish oral immunological tolerance (*Gastroenteroglogy* and *Gut*). Given my accomplishments during my fourth and last year as a postdoctoral training I was supported by Dr. Mora and Dr. Ramnik Xavier (chief of the GI unit) to be promoted Instructor in Medicine at Harvard Medical School. As Instructor in Medicine and in order to start defining my own research path I joined Dr. Xavier lab to study the function of IBD risk genes in the context of intestinal immune homeostasis (*Nat. Comm., Immunity, Cell rep*., etc).
Motivated by cutting-edge research performed as well as the prestige of the institution I decide to look for a position at the Karolinska Institutet. In 2013, I was awarded the Center for Immune Modulatory Therapies for Autoimmnity and Cancer (IMTAC) senior research fellow Based on a scientific plan proposing to study the connection between DC trafficking from the bone marrow and gut immunological tolerance. Hence I started my own research group in November 2014, as an assistant professor at the department of Medicine, Solna (MedS). With background in developmental biology, tumor and mucosal immunology using either zebrafish and mouse models as well as human samples, I believe I am poised to uniquely contribute to elucidate the molecular and cellular mechanisms underlying IBD.
In 2010, I won the prestigious postdoctoral fellow award from the Crohn’s and Colitis Foundation of America (CCFA) and took the lead of a project aimed to further characterize the mechanisms of oral immunological tolerance induction. Hence I started my own research group as an assistant professor at the department of Medicine, Solna (MedS). I have received the Swedish Research Council Young Scientist Award (6 MSEK/4 years), FORMAS (3 MSEK/3 years) and I have been appointed as Wallenberg Academy Fellow (7.5 MSEK/5 years) towards developing a cutting-edge biomedical research program focused on intestinal mucosal immunology. I have achieved national and international recognition for my work as can be inferred from the numerous talks I have been giving in U.S., Europe, Asia and South-America, and from awards and funding I have obtained thus far. I have also been named one of the 40 under 40 most promising Latin-American Scientist by the South American magazine “Que Pasa”.
Selected awards
- Wallenberg Academy Fellow, Knut and Alice Wallenberg foundation (2014)
- IMTAC FoAss position award, chosen as primary candidate (2014)
- CCFA research award, Crohn’s and Colitis Foundation of America (CCFA), NY, USA (2010)
Others awards- 40 under 40 in Latin American Science, Que Pasa magazine (2014)
- Best paper award, San Raffaele Institute, Milan, Italy (2010)
- Best presentation award, RCAI International summer Program 2010, Yokohama,
Japan (2010)
Scholarships and travel awards
- DC2012 Travel Award
- Keystone symposia scholarship, To attend the Mucosal Immunology Symposia, Vancouver, Canada (2011)
- RCAI Fellowship, To attend the RCAI International Summer Program, Yokohama, Japan (2010)
- LACI Scholarship, To attend “The 9th Latin American congress of Immunology”, Chile (2009)
- EMBO Travelling fellowship, To participate in the EMBO practical course: "Enhancer Detection, Gene Trapping and TILLING in Zebrafish”, Bergen, Norway (2005)
- Travelling fellowship Leloir Institute. To attend the course “Gene Therapy in Latin America: from the bench to the clinic”, Buenos Aires, Argentina. (2002)
- ECOS-Conicyt ICM P99-137 Fellowship, To perform research at the laboratory of Dr. Alain Ghysen, Montpellier, France (2002)
Courses and degrees
1998, B.S. Bachelor of Science, University of Chile, Santiago
12/2004, M.Sc.Molecular Biotechnology Engineer University of Chile, Santiago
10/2007, Ph.D. Biomedical Sciences, Immunology, Under the supervision of Vincenzo Russo, M.D., Universita Vita-Salute, Milan
Current position
11/2014 – Present, Assistant Professor, Department of Medicine, Karolinska Institutet
11/2015 – Present Faculty member, SciLifeLab
02/2016 – Present Group Leader, Department of Medicine, Karolinska Institutet
Previous positions including post doc-appointments
03/2008 – 02/2012 Postdoctoral Fellow in Mucosal Immunology, MGH, Harvard Medical School, Boston. Under the supervision of J. Rodrigo Mora, M.D.. Ph.D.
02/2012 – 11/2014 Instructor in Medicine, Harvard Medical School, Boston, MA. Under the supervision of Ramnik J. Xavier, M.D.. Ph.D.
02/2012 – 11/2014 Assistant Immunologist, Massachusetts General Hospital, Boston, MA
03/2012 – 11/2014 Research Scientist, Broad Institute, Cambridge, MA
Research
Our lab is seeking to understand the genetic, cellular and environmental contribution towards inflammatory bowel disease (IBD) susceptibility. We have developed a research program that integrates cellular immunology, bioinformatics, and the creation of novel in vivo models to ultimately interrogate the function of IBD-associated polymorphisms as well as to study host-microbiota interactions. In particular, we are trying to understand how deregulation of intestinal immune homeostasis might lead to IBD and trying to discover the function of IBD-risk genes identified by Genome Wide Association Studies (GWAS).
To discover the function of IBD-risk genes, we focus on biological processes that are involved at the initiation (priming of adaptive immune responses), progression (chronic inflammation) or resolution (tissue repair) of IBD. To translate genetic mutations to function, we have developed an innovative pipeline that integrate bioinformatics and animal models, including zebrafish and mouse, to ultimately validate candidate mutations in human tissues by using organoids. We aim to transform the way in which the gene-environment interactions are currently being investigated.
Selected publications
- Review: MUCOSAL IMMUNOLOGY. 2025;18(1):16-25Villablanca EJ
- Article: NATURE. 2025;637(8048):1198-1206Das S; Parigi SM; Luo X; Fransson J; Kern BC; Okhovat A; Diaz OE; Sorini C; Czarnewski P; Webb AT; Morales RA; Lebon S; Monasterio G; Castillo F; Tripathi KP; He N; Pelczar P; Schaltenberg N; De la Fuente M; Lopez-Kostner F; Nylen S; Larsen HL; Kuiper R; Antonson P; Hermoso MA; Huber S; Biton M; Scharaw S; Gustafsson J-A; Katajisto P; Villablanca EJ
- Article: IMMUNOLOGY AND CELL BIOLOGY. 2025;103(1):27-30Villablanca EJ
- Review: NATURE PROTOCOLS. 2024;19(10):3085-3137Monasterio G; Morales RA; Bejarano DA; Abalo XM; Fransson J; Larsson L; Schlitzer A; Lundeberg J; Das S; Villablanca EJ
Articles
- Journal article: IMMUNOLOGY LETTERS. 2025;277:107071Castillo FA; Kern BC; Villablanca EJ
- Article: MUCOSAL IMMUNOLOGY. 2025;18(4):836-847Morales Castro RA; Kern BC; Díaz-Basabe A; Meinen ER; Zhao D; Zhou Y; Castillo F; Monasterio G; Farcas V; Chávez MN; Fransson J; Villablanca EJ
- Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2025;55(2)Hausmann A; Sandu I; Bechara R; Eidsmo L; Liston A; Naik S; Scott CL; Villa M; Villablanca E; Munoz-Wolf N
- Article: NPJ SYSTEMS BIOLOGY AND APPLICATIONS. 2024;10(1):69Kilian C; Ulrich H; Zouboulis VA; Sprezyna P; Schreiber J; Landsberger T; Buettner M; Biton M; Villablanca EJ; Huber S; Adlung L
- Article: NATURE COMMUNICATIONS. 2024;15(1):1752Kvedaraite E; Lourda M; Mouratidou N; Duking T; Padhi A; Moll K; Czarnewski P; Sinha I; Xagoraris I; Kokkinou E; Damdimopoulos A; Weigel W; Hartwig O; Santos TE; Soini T; Van Acker A; Rahkonen N; Tullberg MF; Ringqvist E; Buggert M; Jorns C; Lindforss U; Nordenvall C; Stamper CT; Unnersjoe-Jess D; Akber M; Nadisauskaite R; Jansson J; Vandamme N; Sorini C; Grundeken ME; Rolandsdotter H; Rassidakis G; Villablanca EJ; Idestroem M; Eulitz S; Arnell H; Mjoesberg J; Henter J-I; Svensson M
- Article: MUCOSAL IMMUNOLOGY. 2024;17(1):81-93Sorini C; Cardoso RF; Tripathi KP; Mold JE; Diaz OE; Holender Y; Kern BC; Czarnewski P; Gagliani N; Villablanca EJ
- Journal article: JOURNAL OF CROHNS & COLITIS. 2024;18:i445-i446Kilian C; Ulrich H; Zouboulis V; Sprezyna P; Buttner M; Biton M; Villablanca EJ; Huber S; Adlung L
- Journal article: JOURNAL OF CROHNS & COLITIS. 2024;18:i328Castillo F; Selin K; Fransson J; Sorini C; Hedin C; Villablanca E
- Journal article: JOURNAL OF CROHNS & COLITIS. 2024;18:i2254Monasterio G; Villablanca E
- Article: NATURE COMMUNICATIONS. 2023;14(1):8402Pennacchietti F; Alvelid J; Morales RA; Damenti M; Ollech D; Oliinyk OS; Shcherbakova DM; Villablanca EJ; Verkhusha VV; Testa I
- Article: FRONTIERS IN MEDICINE. 2023;10:1258395Perez-Jeldres T; Magne F; Ascui G; Alvares D; Orellana M; Alvarez-Lobos M; Hernandez-Rocha C; Azocar L; Aguilar N; Espino A; Estela R; Escobar S; Zazueta A; Baez P; Silva V; de la Vega A; Arriagada E; Pavez-Ovalle C; Diaz-Asencio A; Travisany D; Miquel JF; Villablanca EJ; Kronenberg M; Bustamante ML
- Article: NATURE IMMUNOLOGY. 2023;24(9):1473-1486Siracusa F; Schaltenberg N; Kumar Y; Lesker TR; Steglich B; Liwinski T; Cortesi F; Frommann L; Diercks B-P; Boenisch F; Fischer AW; Scognamiglio P; Pauly MJ; Casar C; Cohen Y; Pelczar P; Agalioti T; Delfs F; Worthmann A; Wahib R; Jagemann B; Mittruecker H-W; Kretz O; Guse AH; Izbicki JR; Lassen KG; Strowig T; Schweizer M; Villablanca EJ; Elinav E; Huber S; Heeren J; Gagliani N
- Article: EBIOMEDICINE. 2023;94:104691Devarakonda S; Thorsell A; Hedenstrom P; Rezapour A; Heden L; Banerjee S; Johansson MEV; Birchenough G; Moren AT; Gustavsson K; Skokic V; Pettersson VL; Sjoberg F; Kalm M; Al Masri M; Ekh M; Fagman H; Wolving M; Perkins R; Morales RA; Castillo F; Villablanca E; Yrlid U; Bergmark K; Steineck G; Bull C
- Journal article: JOURNAL OF HEPATOLOGY. 2023;78:s65Krause J; Casar C; Haenzelmann S; Hausmann F; Khatri R; Engblom C; Das S; Kylies D; Poch T; Schwinge D; Muscate F; Cortesi F; Heumann A; Ghadban T; Fischer L; Clauditz T; Krebs CF; Puelles V; Villablanca E; Huber S; Bonn S; Schramm C; Gagliani N
- Article: CELL REPORTS MEDICINE. 2023;4(5):101038Kokkinou E; Soini T; Pandey RV; van Acker A; Theorell J; Czarnewski P; Kvedaraite E; Vandamme N; Lourda M; Sorini C; Weigel W; Carrasco A; Tibbitt CA; Schlums H; Lindforss U; Nordenvall C; Ljunggren M; Idestrom M; Svensson M; Henter J-I; Villablanca EJ; Bryceson YT; Rolandsdotter H; Mjosberg J
- Article: JCI INSIGHT. 2023;8(4):e161042Sorini C; Tripathi KP; Wu S; Higdon SM; Wang J; Cheng L; Banerjee S; Reinhardt A; Kreslavsky T; Thorell A; Engstrand L; Du J; Villablanca EJ
- Article: NATURE BIOTECHNOLOGY. 2023;41(2):222-231Borm LE; Albiach AM; Mannens CCA; Janusauskas J; Ozgun C; Fernandez-Garcia D; Hodge R; Castillo F; Hedin CRH; Villablanca EJ; Uhlen P; Lein ES; Codeluppi S; Linnarsson S
- Article: IMMUNITY. 2022;55(12):2336-2351.e12Frede A; Czarnewski P; Monasterio G; Tripathi KP; Bejarano DA; Flores ROR; Sorini C; Larsson L; Luo X; Geerlings L; Novella-Rausell C; Zagami C; Kuiper R; Morales RA; Castillo F; Hunt M; Mariano LL; Hu YOO; Engblom C; Lennon-Dumenil A-M; Mittenzwei R; Westendorf AM; Hoevelmeyer N; Lundeberg J; Saez-Rodriguez J; Schlitzer A; Das S; Villablanca EJ
- Article: CANCER RESEARCH COMMUNICATIONS. 2022;2(9):1075-1088Ingelshed K; Spiegelberg D; Kannan P; Pavenius L; Hacheney J; Jiang L; Eisinger S; Lianoudaki D; Lama D; Castillo F; Bosdotter C; Kretzschmar WW; Al-Radi O; Fritz N; Villablanca EJ; Karlsson MCI; Wermeling F; Nestor M; Lane DP; Sedimbi SK
- Article: MUCOSAL IMMUNOLOGY. 2022;15(5):940-951Morales RA; Rabahi S; Diaz OE; Salloum Y; Kern BC; Westling M; Luo X; Parigi SM; Monasterio G; Das S; Hernandez PP; Villablanca EJ
- Article: MUCOSAL IMMUNOLOGY. 2022;15(3):443-458Melhem H; Kaya B; Kaymak T; Wuggenig P; Flint E; Roux J; Oost KC; Cavelti-Weder C; Balmer ML; Walser J-C; Morales RA; Riedel CU; Liberali P; Villablanca EJ; Niess JH
- Article: NATURE COMMUNICATIONS. 2022;13(1):828Parigi SM; Larsson L; Das S; Flores ROR; Frede A; Tripathi KP; Diaz OE; Selin K; Morales RA; Luo X; Monasterio G; Engblom C; Gagliani N; Saez-Rodriguez J; Lundeberg J; Villablanca EJ
- Article: MUCOSAL IMMUNOLOGY. 2022;15(2):257-267Classon CH; Li M; Clavero AL; Ma J; Feng X; Tibbitt CA; Stark JM; Cardoso R; Ringqvist E; Boon L; Villablanca EJ; Rothfuchs AG; Eidsmo L; Coquet JM; Nylen S
- Article: IMMUNITY. 2022;55(1):129-144.e8Rivera CA; Randrian V; Richer W; Gerber-Ferder Y; Delgado M-G; Chikina AS; Frede A; Sorini C; Maurin M; Kammoun-Chaari H; Parigi SM; Goudot C; Cabeza-Cabrerizo M; Baulande S; Lameiras S; Guermonprez P; Reis e Sousa C; Lecuit M; Moreau HD; Helft J; Vignjevic DM; Villablanca EJ; Lennon-Dumenil A-M
- Article: DISEASE MODELS & MECHANISMS. 2021;14(12):dmm049104Diaz OE; Sorini C; Morales RA; Luo X; Frede A; Krais AM; Chavez MN; Wincent E; Das S; Villablanca EJ
- Article: MUCOSAL IMMUNOLOGY. 2021;14(2):411-419Parigi SM; Das S; Frede A; Cardoso RF; Tripathi KP; Donas C; Hu YOO; Antonson P; Engstrand L; Gustafsson J-A; Villablanca EJ
- Article: IMMUNITY. 2021;54(2):259-275.e7Evren E; Ringqvist E; Tripathi KP; Sleiers N; Rives IC; Alisjahbana A; Gao Y; Sarhan D; Halle T; Sorini C; Lepzien R; Marquardt N; Michaelsson J; Smed-Sorensen A; Botling J; Karlsson MCI; Villablanca EJ; Willinger T
- Article: SCIENTIFIC REPORTS. 2020;10(1):22190de Campos Fraga-Silva TF; Nishiyama Mimura LA; Cardoso de Oliveira LR; dos Santos Toledo JH; Borim PA; Goncalvez Zorzella-Pezavento SF; Alonso DP; Martins Ribolla PE; Ferreira de Oliveira CA; da Fonseca DM; Villablanca EJ; Sartori A
- Article: JOURNAL OF CROHNS & COLITIS. 2020;14(12):1748-1758Stakenborg M; Verstockt B; Meroni E; Goverse G; De Simone V; Verstockt S; Di Matteo M; Czarnewski P; Villablanca EJ; Ferrante M; Boeckxstaens GE; Mazzone M; Vermeire S; Matteoli G
- Article: FRONTIERS IN IMMUNOLOGY. 2020;11:591240Monasterio G; Castillo F; Astorga J; Hoare A; Terraza-Aguirre C; Cafferata EA; Villablanca EJ; Vernal R
- Article: CELL REPORTS. 2020;32(5):107979Kaya B; Donas C; Wuggenig P; Diaz OE; Morales RA; Melhem H; Hernandez PP; Kaymak T; Das S; Hruz P; Franc Y; Geier F; Ayata CK; Villablanca EJ; Niess JH
- Article: NATURE COMMUNICATIONS. 2020;11(1):2049Rao A; Strauss O; Kokkinou E; Bruchard M; Tripathi KP; Schlums H; Carrasco A; Mazzurana L; Konya V; Villablanca EJ; Bjorkstrom NK; Lindforss U; Spits H; Mjosberg J
- Article: REPRODUCTIVE TOXICOLOGY. 2020;93:163-168Diaz OE; Xue S; Luo X; Nava J; Appelblom A; Morales RA; Das S; Villablanca EJ
- Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2020;217(2):e20191155Phad GE; Pushparaj P; Tran K; Dubrovskaya V; Adori M; Martinez-Murillo P; Bernat NV; Singh S; Dionne G; O'Dell S; Bhullar K; Narang S; Sorini C; Villablanca EJ; Sundling C; Murrell B; Mascola JR; Shapiro L; Pancera M; Martin M; Corcoran M; Wyatt RT; Hedestam GBK
- Journal article: JOURNAL OF CROHNS & COLITIS. 2020;14(Supplement_1):s641-s642Kulmala K; Diaz OE; Huber S; Hedin C; Villablanca EJ
- Article: NATURE COMMUNICATIONS. 2019;10(1):2892Czarnewski P; Parigi SM; Sorini C; Diaz OE; Das S; Gagliani N; Villablanca EJ
- Article: JOURNAL OF AUTOIMMUNITY. 2019;98:86-94Seitz C; Liu S; Klocke K; Joly A-L; Czarnewski PV; Tibbitt CA; Parigi SM; Westerberg LS; Coquet JM; Villablanca EJ; Wing K; Andersson J
- Article: NATURE COMMUNICATIONS. 2018;9(1):5457Brockmann L; Soukou S; Steglich B; Czarnewski P; Zhao L; Wende S; Bedke T; Ergen C; Manthey C; Agalioti T; Geffken M; Seiz O; Parigi SM; Sorini C; Geginat J; Fujio K; Jacobs T; Roesch T; Izbicki JR; Lohse AW; Flavell RA; Krebs C; Gustafsson J-A; Antonson P; Roncarolo MG; Villablanca EJ; Gagliani N; Huber S
- Article: JOURNAL OF THE ENDOCRINE SOCIETY. 2018;2(12):1363-1380Lindheim L; Manti M; Fornes R; Bashir M; Czarnewski P; Diaz OE; Seifert M; Engstrand L; Villablanca EJ; Obermayer-Pietsch B; Stener-Victorin E
- Article: DISEASE MODELS & MECHANISMS. 2018;11(11):dmm034876Parada-Kusz M; Penaranda C; Hagedorn EJ; Clatworthy A; Nair AV; Henninger JE; Ernst C; Li B; Riquelme R; Jijon H; Villablanca EJ; Zon LI; Hung D; Allende ML
- Article: PLOS ONE. 2018;13(9):e0204181Das S; Donas C; Akeus P; Quiding-Jarbrink M; Mora JR; Villablanca EJ
- Article: MUCOSAL IMMUNOLOGY. 2018;11(3):703-715Jijon HB; Suarez-Lopez L; Diaz OE; Das S; De Calisto J; Yaffe MB; Pittet MJ; Mora JR; Belkaid Y; Xavier RJ; Villablanca EJ
- Article: IMMUNITY. 2018;48(1):120-132.e8Emgard J; Kammoun H; Garcia-Cassani B; Chesne J; Parigi SM; Jacob J-M; Cheng H-W; Evren E; Das S; Czarnewski P; Sleiers N; Melo-Gonzalez F; Kvedaraite E; Svensson M; Scandella E; Hepworth MR; Huber S; Ludewig B; Peduto L; Villablanca EJ; Veiga-Fernandes H; Pereira JOP; Flavell RA; Willinger T
- Article: SCIENTIFIC REPORTS. 2018;8(1):154Parigi SM; Czarnewski P; Das S; Steeg C; Brockmann L; Fernandez-Gaitero S; Yman V; Forkel M; Hoog C; Mjosberg J; Westerberg L; Farnert A; Huber S; Jacobs T; Villablanca EJ
- Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2018;141(1):279-292Konya V; Czarnewski P; Forkel M; Rao A; Kokkinou E; Villablanca EJ; Almer S; Lindforss U; Friberg D; Hoeoeg C; Bergman P; Mjoesberg J
- Journal article: MOLECULAR & CELLULAR PROTEOMICS. 2017;16(8):1547Larssen P; Wik L; Czarnewski P; Eldh M; Lof L; Ronquist KG; Dubois L; Freyhult E; Gallant CJ; Oelrich J; Larsson A; Ronquist G; Villablanca EJ; Landegren U; Gabrielsson S; Kamali-Moghaddam M
- Article: MUCOSAL IMMUNOLOGY. 2017;10(4):884-886Das S; Villablanca EJ
- Article: MOLECULAR & CELLULAR PROTEOMICS. 2017;16(3):502-511Larssen P; Wik L; Czarnewski P; Eldh M; Lof L; Ronquist KG; Dubois L; Freyhult E; Gallant CJ; Oelrich J; Larsson A; Ronquist G; Villablanca EJ; Landegren U; Gabrielsson S; Kamali-Moghaddam M
- Article: IMMUNITY. 2016;44(6):1392-1405Lassen KG; McKenzie CI; Mari M; Murano T; Begun J; Baxt LA; Goel G; Villablanca EJ; Kuo S-Y; Huang H; Macia L; Bhan AK; Batten M; Daly MJ; Reggiori F; Mackay CR; Xavier RJ
- Article: NATURE COMMUNICATIONS. 2015;6:7838Graham DB; Becker CE; Doan A; Goel G; Villablanca EJ; Knights D; Mok A; Ng ACY; Doench JG; Root DE; Clish CB; Xavier RJ
- Article: CELL REPORTS. 2015;11(12):1905-1918Begun J; Lassen KG; Jijon HB; Baxt LA; Goel G; Heath RJ; Ng A; Tam JM; Kuo S-Y; Villablanca EJ; Fagbami L; Oosting M; Kumar V; Schenone M; Carr SA; Joosten LAB; Vyas JM; Daly MJ; Netea MG; Brown GD; Wijmenga C; Xavier RJ
- Article: GUT. 2014;63(9):1431-1440Villablanca EJ; De Calisto J; Paredes PT; Cassani B; Nguyen DD; Gabrielsson S; Mora JR
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2014;111(21):7741-7746Lassen KG; Kuballa P; Conway KL; Patel KK; Becker CE; Peloquin JM; Villablanca EJ; Norman JM; Liu T-C; Heath RJ; Becker ML; Fagbami L; Horn H; Mercer J; Yilmaz OH; Jaffe JD; Shamji AF; Bhan AK; Carr SA; Daly MJ; Virgin HW; Schreiber SL; Stappenbeck TS; Xavier RJ
- Article: GASTROENTEROLOGY. 2013;145(6):1347-1357Conway KL; Kuballa P; Song J-H; Patel KK; Castoreno AB; Yilmaz OH; Jijon HB; Zhang M; Aldrich LN; Villablanca EJ; Peloquin JM; Goel G; Lee I-A; Mizoguchi E; Shi HN; Bhan AK; Shaw SY; Schreiber SL; Virgin HW; Shamji AF; Stappenbeck TS; Reinecker H-C; Xavier RJ
- Article: GASTROENTEROLOGY. 2013;145(3):591-601.e3Sokol H; Conway KL; Zhang M; Choi M; Morin B; Cao Z; Villablanca EJ; Li C; Wijmenga C; Yun SH; Shi HN; Xavier RJ
- Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2013;210(9):1711-1728Raccosta L; Fontana R; Maggioni D; Lanterna C; Villablanca EJ; Paniccia A; Musumeci A; Chiricozzi E; Trincavelli ML; Daniele S; Martini C; Gustafsson J-A; Doglioni C; Feo SG; Leiva A; Ciampa MG; Mauri L; Sensi C; Prinetti A; Eberini I; Mora JR; Bordignon C; Steffensen KR; Sonnino S; Sozzani S; Traversari C; Russo V
- Article: GASTROENTEROLOGY. 2012;143(3):719-729.e2Nguyen DD; Wurbel M-A; Goettel JA; Eston MA; Ahmed OS; Marin R; Boden EK; Villablanca EJ; Paidassi H; Ahuja V; Reinecker H-C; Fiebiger E; Lacy-Hulbert A; Horwitz BH; Mora JR; Snapper SB
- Article: CELL. 2012;149(7):1578-1593Chung H; Pamp SJ; Hill JA; Surana NK; Edelman SM; Troy EB; Reading NC; Villablanca EJ; Wang S; Mora JR; Umesaki Y; Mathis D; Benoist C; Relman DA; Kasper DL
- Journal article: JOURNAL OF IMMUNOLOGY. 2012;188(1_Supplement):120.4Villablanca E; Torregrosa-Paredes P; Cassani B; Wagers A; Mora R
- Article: METHODS IN MOLECULAR BIOLOGY. 2012;757:411-434De Calisto J; Villablanca EJ; Wang S; Bono MR; Rosemblatt M; Mora JR
- Article: GASTROENTEROLOGY. 2011;141(6):2109-2118Cassani B; Villablanca EJ; Quintana FJ; Love PE; Lacy-Hulbert A; Blaner WS; Sparwasser T; Snapper SB; Weiner HL; Mora JR
- Article: JOURNAL OF IMMUNOLOGY. 2011;187(4):1877-1883Kaufman DR; De Calisto J; Simmons NL; Cruz AN; Villablanca EJ; Mora JR; Barouch DH
- Article: JOURNAL OF IMMUNOLOGY. 2011;187(1):141-150Wang S; Villablanca EJ; De Calisto J; Gomes DCO; Nguyen DD; Mizoguchi E; Kagan JC; Reinecker H-C; Hacohen N; Nagler C; Xavier RJ; Rossi-Bergmann B; Chen Y-B; Blomhoff R; Snapper SB; Mora JR
- Article: GASTROENTEROLOGY. 2011;141(1):176-185Villablanca EJ; Wang S; de Calisto J; Gomes DCO; Kane MA; Napoli JL; Blaner WS; Kagechika H; Blomhoff R; Rosemblatt M; Bono MR; von Andrian UH; Mora JR
- Article: GASTROENTEROLOGY. 2011;140(6):1776-1784Villablanca EJ; Cassani B; von Andrian UH; Mora JR
- Journal article: JOURNAL OF IMMUNOLOGY. 2011;186(1_Supplement):161.2Wang S; Villablanca E; Gomes D; Nguyen D; Mizoguchi E; Kagan J; Reinecker H-C; Hacohen N; Nagler C; Xavier R; Rossi-Bergmann B; Chen Y-B; Blomhoff R; Snapper S; Mora R
- Journal article: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2011;(49)Villablanca EJ; Mora JR
- Article: BMC DEVELOPMENTAL BIOLOGY. 2010;10:120Gallardo VE; Liang J; Behra M; Elkahloun A; Villablanca EJ; Russo V; Allende ML; Burgess SM
- Article: NATURE MEDICINE. 2010;16(1):98-105Villablanca EJ; Raccosta L; Zhou D; Fontana R; Maggioni D; Negro A; Sanvito F; Ponzoni M; Valentinis B; Bregni M; Prinetti A; Steffensen KR; Sonnino S; Gustafsson J-A; Doglioni C; Bordignon C; Traversari C; Russo V
- Article: BMC DEVELOPMENTAL BIOLOGY. 2009;9:58Pistocchi A; Feijoo CG; Cabrera P; Villablanca EJ; Allende ML; Cotelli F
- Article: GASTROENTEROLOGY. 2009;137(1):320-329Eksteen B; Mora JR; Haughton EL; Henderson NC; Lee-Turner L; Villablanca EJ; Curbishley SM; Aspinall AI; von Andrian UH; Adams DH
- Article: JOURNAL OF LEUKOCYTE BIOLOGY. 2008;84(3):871-879Villablanca EJ; Zhou D; Valentinis B; Negro A; Raccosta L; Mauri L; Prinetti A; Sonnino S; Bordignon C; Traversari C; Russo V
- Article: JOURNAL OF IMMUNOLOGY. 2007;179(1):357-364Villablanca EJ; Pistocchi A; Court FA; Cotelli F; Bordignon C; Allende ML; Traversari C; Russo V
- Article: DEVELOPMENTAL BIOLOGY. 2006;295(2):534-545Sarrazin AF; Villablanca EJ; Nunez VA; Sandoval PC; Ghysen A; Allende ML
- Article: DEVELOPMENTAL DYNAMICS. 2006;235(6):1578-1588Villablanca EJ; Renucci A; Sapede D; Lec V; Soubiran F; Sandoval PC; Dambly-Chaudiere C; Ghysen A; Allende ML
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All other publications
- Conference publication: EUROPEAN JOURNAL OF IMMUNOLOGY. 2024;54:1344Luo X; Das S; Parigi SM; Castillo F; Villablanca E
- Conference publication: EUROPEAN JOURNAL OF IMMUNOLOGY. 2024;54:1331Monasterio G; Castillo F; van de Ven J; Olmedo V; Larsson L; Frede A; Fransson J; Pietrzak D; Das S; Villablanca E
- Review: NATURE IMMUNOLOGY. 2024;25(3):405-417Schaefer PSL; Dimitrov D; Villablanca EJ; Saez-Rodriguez J
- Conference publication: JOURNAL OF CROHNS & COLITIS. 2024;18:I445-I446Kilian C; Ulrich H; Zouboulis V; Sprezyna P; Buettner M; Biton M; Villablanca EJ; Huber S; Adlung L
- Conference publication: JOURNAL OF CROHNS & COLITIS. 2024;18:I328Castillo F; Selin K; Fransson J; Sorini C; Hedin C; Villablanca E
- Conference publication: JOURNAL OF CROHNS & COLITIS. 2024;18:I2254Monasterio G; Villablanca E
- Preprint: BIORXIV. 2023Kilian C; Ulrich H; Zouboulis V; Sprezyna P; Schreiber J; Landsberger T; Büttner M; Biton M; Villablanca EJ; Huber S; Adlung L
- Conference publication: GLIA. 2023;71:E810Lukoseviciute M; Monasterio G; Llorens-Bobadilla E; Villablanca EJ; Frisen J
- Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2023Ingelshed K; Spiegelberg D; Kannan P; Påvénius L; Hacheney J; Jiang L; Eisinger S; Lianoudaki D; Lama D; Castillo F; Bosdotter C; Kretzschmar WW; Al-Radi O; Fritz N; Villablanca EJ; Karlsson MCI; Wermeling F; Nestor M; Lane DP; Sedimbi SK
- Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2023Ingelshed K; Spiegelberg D; Kannan P; Påvénius L; Hacheney J; Jiang L; Eisinger S; Lianoudaki D; Lama D; Castillo F; Bosdotter C; Kretzschmar WW; Al-Radi O; Fritz N; Villablanca EJ; Karlsson MCI; Wermeling F; Nestor M; Lane DP; Sedimbi SK
- Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2023Ingelshed K; Spiegelberg D; Kannan P; Påvénius L; Hacheney J; Jiang L; Eisinger S; Lianoudaki D; Lama D; Castillo F; Bosdotter C; Kretzschmar WW; Al-Radi O; Fritz N; Villablanca EJ; Karlsson MCI; Wermeling F; Nestor M; Lane DP; Sedimbi SK
- Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2023Ingelshed K; Spiegelberg D; Kannan P; Påvénius L; Hacheney J; Jiang L; Eisinger S; Lianoudaki D; Lama D; Castillo F; Bosdotter C; Kretzschmar WW; Al-Radi O; Fritz N; Villablanca EJ; Karlsson MCI; Wermeling F; Nestor M; Lane DP; Sedimbi SK
- Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2023Ingelshed K; Spiegelberg D; Kannan P; Påvénius L; Hacheney J; Jiang L; Eisinger S; Lianoudaki D; Lama D; Castillo F; Bosdotter C; Kretzschmar WW; Al-Radi O; Fritz N; Villablanca EJ; Karlsson MCI; Wermeling F; Nestor M; Lane DP; Sedimbi SK
- Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2023Ingelshed K; Spiegelberg D; Kannan P; Påvénius L; Hacheney J; Jiang L; Eisinger S; Lianoudaki D; Lama D; Castillo F; Bosdotter C; Kretzschmar WW; Al-Radi O; Fritz N; Villablanca EJ; Karlsson MCI; Wermeling F; Nestor M; Lane DP; Sedimbi SK
- Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2023Ingelshed K; Spiegelberg D; Kannan P; Påvénius L; Hacheney J; Jiang L; Eisinger S; Lianoudaki D; Lama D; Castillo F; Bosdotter C; Kretzschmar WW; Al-Radi O; Fritz N; Villablanca EJ; Karlsson MCI; Wermeling F; Nestor M; Lane DP; Sedimbi SK
- Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2023Ingelshed K; Spiegelberg D; Kannan P; Påvénius L; Hacheney J; Jiang L; Eisinger S; Lianoudaki D; Lama D; Castillo F; Bosdotter C; Kretzschmar WW; Al-Radi O; Fritz N; Villablanca EJ; Karlsson MCI; Wermeling F; Nestor M; Lane DP; Sedimbi SK
- Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2023Ingelshed K; Spiegelberg D; Kannan P; Påvénius L; Hacheney J; Jiang L; Eisinger S; Lianoudaki D; Lama D; Castillo F; Bosdotter C; Kretzschmar WW; Al-Radi O; Fritz N; Villablanca EJ; Karlsson MCI; Wermeling F; Nestor M; Lane DP; Sedimbi SK
- Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2023Ingelshed K; Spiegelberg D; Kannan P; Påvénius L; Hacheney J; Jiang L; Eisinger S; Lianoudaki D; Lama D; Castillo F; Bosdotter C; Kretzschmar WW; Al-Radi O; Fritz N; Villablanca EJ; Karlsson MCI; Wermeling F; Nestor M; Lane DP; Sedimbi SK
- Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2023Ingelshed K; Spiegelberg D; Kannan P; Påvénius L; Hacheney J; Jiang L; Eisinger S; Lianoudaki D; Lama D; Castillo F; Bosdotter C; Kretzschmar WW; Al-Radi O; Fritz N; Villablanca EJ; Karlsson MCI; Wermeling F; Nestor M; Lane DP; Sedimbi SK
- Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2023Ingelshed K; Spiegelberg D; Kannan P; Påvénius L; Hacheney J; Jiang L; Eisinger S; Lianoudaki D; Lama D; Castillo F; Bosdotter C; Kretzschmar WW; Al-Radi O; Fritz N; Villablanca EJ; Karlsson MCI; Wermeling F; Nestor M; Lane DP; Sedimbi SK
- Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2023Ingelshed K; Spiegelberg D; Kannan P; Påvénius L; Hacheney J; Jiang L; Eisinger S; Lianoudaki D; Lama D; Castillo F; Bosdotter C; Kretzschmar WW; Al-Radi O; Fritz N; Villablanca EJ; Karlsson MCI; Wermeling F; Nestor M; Lane DP; Sedimbi SK
- Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2023Ingelshed K; Spiegelberg D; Kannan P; Påvénius L; Hacheney J; Jiang L; Eisinger S; Lianoudaki D; Lama D; Castillo F; Bosdotter C; Kretzschmar WW; Al-Radi O; Fritz N; Villablanca EJ; Karlsson MCI; Wermeling F; Nestor M; Lane DP; Sedimbi SK
- Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2023Ingelshed K; Spiegelberg D; Kannan P; Påvénius L; Hacheney J; Jiang L; Eisinger S; Lianoudaki D; Lama D; Castillo F; Bosdotter C; Kretzschmar WW; Al-Radi O; Fritz N; Villablanca EJ; Karlsson MCI; Wermeling F; Nestor M; Lane DP; Sedimbi SK
- Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2023Ingelshed K; Spiegelberg D; Kannan P; Påvénius L; Hacheney J; Jiang L; Eisinger S; Lianoudaki D; Lama D; Castillo F; Bosdotter C; Kretzschmar WW; Al-Radi O; Fritz N; Villablanca EJ; Karlsson MCI; Wermeling F; Nestor M; Lane DP; Sedimbi SK
- Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2023Ingelshed K; Spiegelberg D; Kannan P; Påvénius L; Hacheney J; Jiang L; Eisinger S; Lianoudaki D; Lama D; Castillo F; Bosdotter C; Kretzschmar WW; Al-Radi O; Fritz N; Villablanca EJ; Karlsson MCI; Wermeling F; Nestor M; Lane DP; Sedimbi SK
- Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2023Ingelshed K; Spiegelberg D; Kannan P; Påvénius L; Hacheney J; Jiang L; Eisinger S; Lianoudaki D; Lama D; Castillo F; Bosdotter C; Kretzschmar WW; Al-Radi O; Fritz N; Villablanca EJ; Karlsson MCI; Wermeling F; Nestor M; Lane DP; Sedimbi SK
- Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2023Ingelshed K; Spiegelberg D; Kannan P; Påvénius L; Hacheney J; Jiang L; Eisinger S; Lianoudaki D; Lama D; Castillo F; Bosdotter C; Kretzschmar WW; Al-Radi O; Fritz N; Villablanca EJ; Karlsson MCI; Wermeling F; Nestor M; Lane DP; Sedimbi SK
- Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2023Ingelshed K; Spiegelberg D; Kannan P; Påvénius L; Hacheney J; Jiang L; Eisinger S; Lianoudaki D; Lama D; Castillo F; Bosdotter C; Kretzschmar WW; Al-Radi O; Fritz N; Villablanca EJ; Karlsson MCI; Wermeling F; Nestor M; Lane DP; Sedimbi SK
- Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2023Ingelshed K; Spiegelberg D; Kannan P; Påvénius L; Hacheney J; Jiang L; Eisinger S; Lianoudaki D; Lama D; Castillo F; Bosdotter C; Kretzschmar WW; Al-Radi O; Fritz N; Villablanca EJ; Karlsson MCI; Wermeling F; Nestor M; Lane DP; Sedimbi SK
- Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2023Ingelshed K; Spiegelberg D; Kannan P; Påvénius L; Hacheney J; Jiang L; Eisinger S; Lianoudaki D; Lama D; Castillo F; Bosdotter C; Kretzschmar WW; Al-Radi O; Fritz N; Villablanca EJ; Karlsson MCI; Wermeling F; Nestor M; Lane DP; Sedimbi SK
- Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2023Ingelshed K; Spiegelberg D; Kannan P; Påvénius L; Hacheney J; Jiang L; Eisinger S; Lianoudaki D; Lama D; Castillo F; Bosdotter C; Kretzschmar WW; Al-Radi O; Fritz N; Villablanca EJ; Karlsson MCI; Wermeling F; Nestor M; Lane DP; Sedimbi SK
- Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2023Ingelshed K; Spiegelberg D; Kannan P; Påvénius L; Hacheney J; Jiang L; Eisinger S; Lianoudaki D; Lama D; Castillo F; Bosdotter C; Kretzschmar WW; Al-Radi O; Fritz N; Villablanca EJ; Karlsson MCI; Wermeling F; Nestor M; Lane DP; Sedimbi SK
- Preprint: BIORXIV. 2023;BIORXIVScharaw S; Sola-Carvajal A; Belevich I; Webb AT; Das S; Andersson S; Pentinmikko N; Villablanca EJ; Goldenring JR; Jokitalo E; Coffey RJ; Katajisto P
- Review: NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY. 2022;19(8):493-507Villablanca EJ; Selin K; Hedin CRH
- Book chapter: CELL MOVEMENT IN HEALTH AND DISEASE. 2022;p.Monasterio Ocares GA; Castillo F; Villablanca E
- Book chapter: CELL MOVEMENT IN HEALTH AND DISEASE. 2022;p. 203-235Monasterio G; Castillo FA; Villablanca EJ
- Preprint: MEDRXIV. 2021Sorini C; Tripathi K; Wu S; Higdon S; Wang J; Cheng L; Banerjee S; Reinhardt A; Kreslavsky T; Thorell A; Engstrand L; Du J; Villablanca E
- Review: JOURNAL OF CROHNS & COLITIS. 2021;15(11):1959-1973Selin KA; Hedin CRH; Villablanca EJ
- Review: BIOCHEMICAL SOCIETY TRANSACTIONS. 2021;49(5):2371-2380Luo X; Villablanca EJ
- Conference publication: SWISS MEDICAL WEEKLY. 2021;151:2Melhem H; Kaya B; Kaymak T; Wuggenig P; Niess JH
- Conference publication: EUROPEAN JOURNAL OF IMMUNOLOGY. 2021;51:35Evren E; Ringqvist E; Tripathi KP; Sleiers N; Rives IC; Alisjahbana A; Michaelsson J; Sorensen AS; Botling J; Karlsson MCI; Villablanca EJ; Willinger T
- Conference publication: EUROPEAN JOURNAL OF IMMUNOLOGY. 2021;51:89Das S; Parigi SM; Scharaw S; Luo X; Diaz OE; Webb A; Zagami C; Pelczar P; De La Fuente M; Czarnewski P; Lopez Kostner F; Nylen S; Antonson P; Hermoso MA; Huber S; Gustafsson JA; Katajisto P; Villablanca EJ
- Preprint: BIORXIV. 2021Parigi S; Larsson L; Das S; Ramirez Flores R; Frede A; Tripathi K; Diaz O; Selin K; Morales R; Luo X; Monasterio G; Engblom C; Gagliani N; Saez-Rodriguez J; Lundeberg J; Villablanca E
- Editorial comment: IMMUNITY. 2021;54(6):1097-1099Sorini C; Villablanca EJ
- Preprint: BIORXIV. 2021Classon CH; Li M; Ma J; Clavero L; Feng X; Tibbitt CA; Stark JM; Cardoso R; Ringqvist E; Boon L; Villablanca EJ; Rothfuchs G; Eidsmo L; Coquet JM; Nylén S
- Preprint: BIORXIV. 2021Melhem H; Kaya B; Kaymak T; Wuggenig P; Flint E; Roux J; Cavelti-Weder C; Balmer M; Walser J-C; Morales R; Riedel C; Liberali P; Villablanca E; Niess JH
- Preprint: SSRN ELECTRONIC JOURNAL. 2021Frede A; Tripathi KP; Czarnewski P; Monasterio G; Flores ROR; Sorini C; larsson L; Luo X; Novella-Rausell C; Zagami C; Hu YOO; Engblom C; Mittenzwei R; Hövelmeyer N; Lundeberg J; Das S; Saez-Rodriguez J; Villablanca EJ
- Other: GASTROENTEROLOGY. 2020;158(5):1506-1508Perez-Jeldres T; Alvarez-Lobos M; Rivera Nieves J; Villablanca EJ
- Preprint: BIORXIV. 2020Kaya B; Cuadra CD; Wuggenig P; Diaz O; Morales R; Melhem H; Swiss IBD Cohort Investigators; Hernández P; Kaymak T; Das S; Hruz P; Ayata K; Villablanca E; Niess JH
- Conference publication: JOURNAL OF CROHNS & COLITIS. 2020;14:S641-S642Kulmala K; Diaz OE; Huber S; Hedin C; Villablanca EJ
- Preprint: BIORXIV. 2019Parigi S; Das S; Frede A; Cardoso R; Tripathi KP; Doñas C; Hu Y; Antonson P; Engstrand L; Gustafsson J-Å; Villablanca E
- Conference publication: SWISS MEDICAL WEEKLY. 2019;:3SKaya B; Cuadra CD; Wuggenig P; Melhem H; Kaymak T; Ayata K; Hruz P; Villablanca EJ; Niess JH
- Conference publication: SHOCK. 2019;51(6):41-42Suarez-Lopez L; De la Rosa X; Sriram G; Kong YW; Morandell S; Merrick KA; Hernandez Y; Villablanca EJ; Haigis KM; Yaffe MB
- Corrigendum: MUCOSAL IMMUNOLOGY. 2019;12(2):580Jijon HB; Suarez-Lopez L; Diaz OE; Das S; De Calisto J; Parada-Kusz M; Yaffe MB; Pittet MJ; Mora JR; Belkaid Y; Xavier RJ; Villablanca EJ; Parada-kusz M
- Conference publication: JOURNAL OF CROHNS & COLITIS. 2019;13:S123Czarnewski P; Parigi M; Diaz O; Das S; Sorini C; Gagliani N; Villablanca EJ
- Preprint: BIORXIV. 2019Czarnewski P; Parigi S; Sorini C; Diaz O; Das S; Gagliani N; Villablanca E
- Review: FRONTIERS IN IMMUNOLOGY. 2019;9:3177Siracusa F; Schaltenberg N; Villablanca EJ; Huber S; Gagliani N
- Book chapter: MOLECULAR GENETICS OF INFLAMMATORY BOWEL DISEASE. 2019;p. 47-76Diaz OE; Morales RA; Das S; Villablanca EJ
- Preprint: SSRN ELECTRONIC JOURNAL. 2019Randrian V; Rivera CA; Chikina A; Richer W; Parigi SM; Maurin M; Goudot C; Krndija D; Czarnewski P; Baulande S; Lameiras S; Helft J; Guermonprez P; Moreau HD; Vignjevic DM; Villablanca EJ; Lennon-Duménil A-M
- Review: FRONTIERS IN IMMUNOLOGY. 2018;9:2667Sorini C; Cardoso RF; Gagliani N; Villablanca EJ
- Review: JOURNAL OF AUTOIMMUNITY. 2018;87:50-60Agalioti T; Villablanca EJ; Huber S; Gagliani N
- Preprint: BIORXIV. 2017Parada-Kusz M; Clatworthy A; Hagedorn E; Penaranda C; Nair A; Henninger J; Ernst C; Li B; Riquelme R; Jijon H; Villablanca E; Zon L; Hung D; Allende M
- Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):288Larssen P; Eldh M; Veerman R; Villablanca E; Gabrielsson S
- Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):271Immunomodulatory effects of perfluoroalkyl substances during chemically induced colitis in zebrafishAppelblom A; Diaz OE; Das S; Wincent E; Villablanca EJ
- Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):291-292Czarnewski P; Parigi M; Diaz O; Villablanca EJ
- Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):269Parigi SM; Czarnewski P; Villablanca EJ
- Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):293Parigi SM; Das S; Barenco PVC; Sorini C; Perez OD; Antonson P; Gustafsson J-A; Villablanca EJ
- Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):268Sorini C; Parigi SM; Das S; Czarnewski P; Garimella M; Karlsson M; Villablanca EJ
- Review: NUTRIENTS. 2017;9(1):E68-68Czarnewski P; Das S; Parigi SM; Villablanca EJ
- Review: ANNUAL REVIEW OF IMMUNOLOGY. 2016;34:31-64Peloquin JM; Goel G; Villablanca EJ; Xavier RJ
- Review: FRONTIERS IN IMMUNOLOGY. 2015;6:415Parigi SM; Eldh M; Larssen P; Gabrielsson S; Villablanca EJ
- Conference publication: CANCER RESEARCH. 2013;73(8):lb-346-lb-346Russo V; Raccosta L; Fontana R; Maggioni D; Lanterna C; Paniccia A; Musumeci A; Doglioni C; Leiva A; Villablanca EJ; Mora R; Chiricozzi E; Ciampa MG; Mauri L; Prinetti A; Sonino S; Trincavelli ML; Daniele S; Martini C; Steffensen K; Gustafsson J-A; Feo SG; Bordignon C; Traversari C; Sozzani S
- Editorial comment: ONCOIMMUNOLOGY. 2013;2(2):e22987Villablanca EJ
- Editorial comment: EUROPEAN JOURNAL OF IMMUNOLOGY. 2012;42(12):3136-3140De Calisto J; Villablanca EJ; Mora JR
- Review: MOLECULAR ASPECTS OF MEDICINE. 2012;33(1):63-76Cassani B; Villablanca EJ; De Calisto J; Wang S; Mora JR
- Editorial comment: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2011;(49):2619Villablanca EJ; Mora JR
- Editorial comment: EUROPEAN JOURNAL OF IMMUNOLOGY. 2008;38(11):2975-2980Villablanca EJ; Mora JR
- Review: HISTOLOGY AND HISTOPATHOLOGY. 2008;23(7):897-910Villablanca EJ; Russo V; Mora JR
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Grants
- Swedish Research Council for Environment Agricultural Sciences and Spatial Planning1 January 2023 - 31 December 2025Perfluoroalkyl substances (PFAS), such as perfluorooctane sulfonic acid (PFOS), perfluorooctanoic acid (PFOA), and perfluoro hexane sulfonic acid (PFHxS) are a widespread class of man-made persistent, mobile and bioaccumulating pollutants that have been detected in humans, wildlife, and the environment. PFAS are high-risk chemicals causing detrimental health effects and have been linked to many metabolic, developmental, and immunological alterations. Among immunological alterations, PFAS has been associated with intestinal inflammatory diseases and poor responses to COVID-19 vaccination. Our recent FORMAS-supported findings indicate that PFOS disrupts the intestinal barrier function leading to exacerbated inflammation (Diaz et al., DMM, 2021). However, how PFAS affects immune responses that may lead to immune-mediated diseases and poor response to vaccination is yet to be fully understood. Here, using experimental models and systems immunology approaches, we will follow up on our studies to understand the immunotoxic effects of PFAS in intestinal autoimmune diseases and vaccine outcomes. This research will drive novel insights on the role of environmental factors in the etiology of immune-mediated inflammatory diseases and response to vaccines and will provide much-needed knowledge to enable citizens and policymakers to make informed decisions to protect the society at risk of high PFAS exposure.
- Characterization of UC1 and UC2 patients; towards precision medicine in UCCrohn's and Colitis Foundation1 July 2022 - 30 June 2023
- Swedish Research Council1 December 2021 - 30 November 2025Harnessing the power of tissue regeneration to promote resolution in chronic autoimmune diseases such as ulcerative colitis (UC) is a promising approach, as mucosal healing predicts sustained remission. However, uncontrolled regeneration may lead to tumor growth, highlighting the need to identify pathways unlinking regeneration and tumorigenesis. My lab has identified liver X receptor (LXR) pathway whose activation promotes intestinal regeneration while inhibiting tumorigenesis in vivo. How LXR unlinks regeneration and tumorigenesis is not known. Using pharmacological tools and genetically engineered mouse models, we will first investigate the mechanisms how LXR activation promotes mucosal healing and inhibits tumor growth. Additionally, we have stratified UC patients into two novel subtypes namely UC1 and UC2. Since the UC1 profile is associated with increased tissue injury and poor response to therapies, we will test whether the stratification into UC1 and UC2 depends on the degree of tissue damage and capacity to heal. Using single-cell transcriptomics, we will generate an atlas of tissue regeneration in UC1 and UC2 patients and test if organoids from UC1 patients display signs of mucosal healing upon LXR activation. We will complement our studies with organoid-immune/stromal co-culture to test the positively identified pathways (eg LXR). This will pave the way towards personalized medicine in UC by identifying novel targets for boosting safer regeneration in UC patients.
- Swedish Research Council1 January 2019 - 31 December 2021
- Swedish Research Council for Environment Agricultural Sciences and Spatial Planning1 January 2017 - 31 December 2019
- Deutsche Forschungsgemeinschaft1 January 2017 - 31 December 2019
- Swedish Research Council1 January 2015 - 31 December 2018
- Role of retinoic acid in dendritic cell 'education' in the gut: Implications for tolerogenic mucosaCrohn's and Colitis Foundation1 July 2010 - 30 June 2013
Employments
- Professor, Department of Medicine, Karolinska Institutet, 2025-
- Principal Researcher, Department of Medicine, Karolinska Institutet, 2022-2024
Degrees and Education
- Docent, Karolinska Institutet, 2018