Michael Ratz

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About me

CV
2023-present: Group Leader, Karolinska Institute
2023: Visiting Scholar, Deisseroth lab (Stanford University, USA)
2021-2023: Researcher, Lundeberg lab (KTH, Sweden)
2016-2021: Postdoc, Frisén lab (Karolinska Institute, Sweden)
2012-2016: PhD, Jakobs Lab (Max Planck Institute for Biophysical Chemistry, Germany)

Articles

Article: NATURE COMMUNICATIONS. 2024;15(1):3475
High clonal diversity and spatial genetic admixture in early prostate cancer and surrounding normal tissue
Zhang N; Harbers L; Simonetti M; Diekmann C; Verron Q; Berrino E; Bellomo SE; Longo GMC; Ratz M; Schultz N; Tarish F; Su P; Han B; Wang W; Onorato S; Grassini D; Ballarino R; Giordano S; Yang Q; Sapino A; Frisen J; Alkass K; Druid H; Roukos V; Helleday T; Marchio C; Bienko M; Crosetto N
Article: CELL SYSTEMS. 2024;15(2):149-165.e10
Clonally heritable gene expression imparts a layer of diversity within cell types
Mold JE; Weissman MH; Ratz M; Hagemann-Jensen M; Hard J; Eriksson C-J; Toosi H; Berghenstrahle J; Ziegenhain C; von Berlin L; Martin M; Blom K; Lagergren J; Lundeberg J; Sandberg R; Michaeeurolsson J; Frisen J
Journal article: JOURNAL OF HEPATOLOGY. 2023;78:s439
SAT-365 Lineage tracing of hepatic stellate cells with ultrasound-guided in utero nano-injection
He J; Belicova L; De Haan S; Van Hul NKM; Verhulst S; Ratz M; Andersson E
Article: HIPPOCAMPUS. 2023;33(4):391-401
Early fate bias in neuroepithelial progenitors of hippocampal neurogenesis
von Berlin L; Westholm JO; Ratz M; Frisen J
Article: NATURE NEUROSCIENCE. 2022;25(3):285-294
Clonal relations in the mouse brain revealed by single-cell and spatial transcriptomics
Ratz M; von Berlin L; Larsson L; Martin M; Westholm JO; La Manno G; Lundeberg J; Frisen J
Article: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 2021;1506(1):74-97
Single cell biology-a Keystone Symposia report
Cable J; Elowitz MB; Domingos AI; Habib N; Itzkovitz S; Hamidzada H; Balzer MS; Yanai I; Liberali P; Whited J; Streets A; Cai L; Stergachis AB; Hong CKY; Keren L; Guilliams M; Alon U; Shalek AK; Hamel R; Pfau SJ; Raj A; Quake SR; Zhang NR; Fan J; Trapnell C; Wang B; Greenwald NF; Vento-Tormo R; Santos SDM; Spencer SL; Garcia HG; Arekatla G; Gaiti F; Arbel-Goren R; Rulands S; Junker JP; Klein AM; Morris SA; Murray JI; Galloway KE; Ratz M; Romeike M
Article: NATURE GENETICS. 2021;53(5):694-706
Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin
Kameneva P; Artemov AV; Kastriti ME; Faure L; Olsen TK; Otte J; Erickson A; Semsch B; Andersson ER; Ratz M; Frisen J; Tischler AS; de Krijger RR; Bouderlique T; Akkuratova N; Vorontsova M; Gusev O; Fried K; Sundstrom E; Mei S; Kogner P; Baryawno N; Kharchenko PV; Adameyko I
Article: NATURE BIOTECHNOLOGY. 2021;39(5):609-618
Volumetric live cell imaging with three-dimensional parallelized RESOLFT microscopy
Boden A; Pennacchietti F; Coceano G; Damenti M; Ratz M; Testa I
Article: NATURE COMMUNICATIONS. 2018;9(1):3281
Enhanced photon collection enables four dimensional fluorescence nanoscopy of living systems
Masullo LA; Boden A; Pennacchietti F; Coceano G; Ratz M; Testa I
Article: ACS CHEMICAL BIOLOGY. 2018;13(2):475-480
Two-Color 810 nm STED Nanoscopy of Living Cells with Endogenous SNAP-Tagged Fusion Proteins
Butkevich AN; Ta H; Ratz M; Stoldt S; Jakobs S; Belov VN; Hell SW
Article: SCIENTIFIC REPORTS. 2017;7(1):16327
STRT-seq-2i: dual-index 5′ single cell and nucleus RNA-seq on an addressable microwell array
Hochgerner H; Lonnerberg P; Hodge R; Mikes J; Heskol A; Hubschle H; Lin P; Picelli S; La Manno G; Ratz M; Dunne J; Husain S; Lein E; Srinivasan M; Zeisel A; Linnarsson S
Article: SCIENTIFIC REPORTS. 2015;5:9592
CRISPR/Cas9-mediated endogenous protein tagging for RESOLFT super-resolution microscopy of living human cells
Ratz M; Testa I; Hell SW; Jakobs S
Article: NATURE METHODS. 2013;10(8):737-740
Nanoscopy with more than 100,000 'doughnuts'
Chmyrov A; Keller J; Grotjohann T; Ratz M; d'Este E; Jakobs S; Eggeling C; Hell SW

All other publications

Preprint: BIORXIV. 2024
In-situ architecture of the human prohibitin complex
Lange F; Ratz M; Dohrke J-N; Wenzel D; Ilgen P; Riedel D; Jakobs S
Preprint: BIORXIV. 2023
High clonal diversity and spatial genetic admixture in early prostate cancer and surrounding normal tissue
Zhang N; Harbers L; Simonetti M; Diekmann C; Verron Q; Berrino E; Bellomo SE; Longo GMC; Ratz M; Schultz N; Tarish F; Su P; Han B; Wang W; Onorato S; Giordano S; Yang Q; Sapino A; Frisén J; Alkass K; Druid H; Roukos V; Helleday T; Marchiò C; Bienko M; Crosetto N
Conference publication: JOURNAL OF HEPATOLOGY. 2023;78:S439
Lineage tracing of hepatic stellate cells with ultrasound-guided in utero nano-injection
He J; Belicova L; De Haan S; Van Hul NKM; Verhulst S; Ratz M; Andersson E
Preprint: BIORXIV. 2022
Clonally heritable gene expression imparts a layer of diversity within cell types
Mold J; Weissman M; Ratz M; Hagemann-Jensen M; Hård J; Eriksson C-J; Toosi H; Berghenstråhle J; von Berlin L; Martin M; Blom K; Lagergren J; Lundeberg J; Sandberg R; Michaëlsson J; Frisén J
Preprint: BIORXIV. 2021
Cell types and clonal relations in the mouse brain revealed by single-cell and spatial transcriptomics
Ratz M; von Berlin L; Larsson L; Martin M; Westholm JO; La Manno G; Lundeberg J; Frisén J
Preprint: BIORXIV. 2018
Enhanced photon collection enables four dimensional fluorescence nanoscopy of living systems
Masullo L; Bodén A; Pennacchietti F; Coceano G; Ratz M; Testa I
Preprint: BIORXIV. 2017
STRT-seq-2i: dual-index 5′ single cell and nucleus RNA-seq on an addressable microwell array
Hochgerner H; Lönnerberg P; Hodge R; Mikes J; Heskol A; Hubschle H; Lin P; Picelli S; Manno GL; Ratz M; Dunne J; Husain S; Lein E; Srinivasan M; Zeisel A; Linnarsson S

Grants

Molecular dissection of neural circuit assembly
Swedish Research Council
1 January 2023 - 31 December 2026
Deciphering the molecular networks that govern the neurogenic potential of astrocytes in the adult mouse brain
Deutsche Forschungsgemeinschaft
1 January 2017 - 31 December 2019

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