Neo-IsoCore - user publications
A selection of recent publications and news articles using our core facility's procedures may be seen on this page. Currently, several manuscripts are under preparation.
Publications
Post mortem validation and mechanistic study of UCB-J in progressive supranuclear palsy patients' brains.
Scarpa M, Vallera E, Ausellé-Bosch S, Rocha FM, Mercan BE, Roy A, Nordberg A, Kumar A
Alzheimers Dement 2025 Feb;21(2):e14409
Mapping reactive astrogliosis in Parkinson's brain with astroglial tracers BU99008 and Deprenyl: New insights from a multi-marker postmortem study.
Rocha FM, Roy A, Varshney M, Kumar A
Alzheimers Dement 2025 Feb;21(2):e14488
Tracing synaptic loss in Alzheimer's brain with SV2A PET-tracer UCB-J.
Kumar A, Scarpa M, Nordberg A
Alzheimers Dement 2024 Apr;20(4):2589-2605
News articles
Photo: UnsplashNew research uncovers brain changes in Parkinson’s Disease
Researchers at Karolinska Institutet have discovered new insights into brain changes in Parkinson’s disease using advanced imaging techniques.
Photo: IllustrationNew study sheds light on Progressive Supranuclear Palsy
Progressive supranuclear palsy (PSP) is a severe and rapidly progressing neurodegenerative disease that affects both motor and cognitive functions. Often misdiagnosed or underdiagnosed due to a lack of specific biomarkers, PSP has posed significant challenges for accurate diagnosis and treatment. However, a new study published in the journal Alzheimer & Dementia: The Journal of the Alzheimer's Associationoffers promising insights into this debilitating condition.
Photo: Getty Images,Getty Images/iStockphotoProgress in spotting early signs of Alzheimer’s disease
Researchers at Karolinska Institutet have made exciting discoveries about Alzheimer's disease, a common form of dementia affecting millions of people around the world. In a study published in Alzheimer's & Dementia: The Journal of the Alzheimer's Association, they have explored the potential of novel synaptic PET-tracer UCB-J as an important early diagnostic biomarker/tool for Alzheimer's disease.