CRISPR Functional Genomics
We specialize in harnessing the power of CRISPR technology to accelerate scientific discovery. Our expertise spans a diverse range of applications, from precise genome engineering in cell lines to high-throughput genetic perturbations for screening and unbiased discovery. As a SciLifeLab National Infrastructure unit, we are accessible to the entire Swedish research community and are dedicated to delivering cutting-edge services to push the boundaries of technological innovation.
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Photo: Mikael Wallerstedt.CRISPR Functional Genomics
CFG offers massively parallel genetic perturbations and genetic screening for unbiased discovery. Examples of our toolbox include genome-wide or custom CRISPR-based loss- and gain-of-function screens, small screens coupled with single cell transcriptomics as a readout, base-editing tiling mutagenesis screens and other modalities.
Photo: Mikael Wallerstedt.Precision Genome Engineering
CFG provides flexible and affordable gene-editing services in cells. We offer knock-outs knock-ins, and point mutations in your cell type of choice.
Photo: Lotte BrandtFacts about our core facility
Location: Biomedicum, quarter 9B
Director: Bernhard Schmierer
Key words: CRISPR/Cas, pooled screening, precision editing, knock-out, knock-in, base editing, prime editing
Department: Medical Biochemistry and Biophysics (MBB)
Funding: Karolinska Institutet and SciLifeLab
External website: CRISPR Functional Genomics Infrastructure Unit
Photo: Lasse Skog