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Animal experimental core facilities

At Karolinska Institutet, the managing organisation for all aspects of animal experimentation in research is Comparative Medicine. Our scientists also have access to animal facilities managed by the Karolinska University Hospital.

KI professor Abdel El Manira at the Zebrafish facility, credit: Stefan Zimmerman.
KI professor Abdel El Manira at the Zebrafish facility. Credit: Stefan Zimmerman.

Animal Behavior Core Facility (ABCF)

The Animal Behavior Core Facility (ABCF) is the new core facility at Karolinska Institutet for behavioral studies in mice and rats. ABCF is designed to provide optimal environment, state-of-the-art instrumentation and technical/educational support to perform behavioral tests ranging from basic phenotype characterization to advanced analyses.

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Import Portal

The KIMM Import Portal (Portalen in Swedish) is the animal quarantine core facility within the Karolinska Institutet Mouse Models (KIMM) organisation.

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Infinigene

Manipulation of gene expression during mouse development is a powerful tool for querying the role of specific genes in development and disease. Infinigene is a facility which utilizes ultrasound-guided nano-injection to introduce DNA-modifying agents during embryonic development, or in adult mice.

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Karolinska Experimental Research and Imaging Centre

Karolinska Experimental Research and Imaging Centre (KERIC) conducts Imaging analyses in experimental systems in combination with experimental surgery in large animals like swine as well as in rodents. This facility is managed by the Karolinska University Hospital in Solna (North Campus area).

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Karolinska Institutet Mouse Models

The Karolinska Institutet Mouse Models (KIMM) is a core facility umbrella offering production, phenotype analyses, archiving of mouse mutants and experimental platforms to understand the role of genes and the microbiota. The KIMM umbrella facility includes the KCTT facility, the Germ-free facility and an import portal.

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Morphological Phenotype Analysis

Morphological Phenotype Analysis (FENO) facility specialises in the pathology of genetically engineered mice. This core facility is managed by the Karolinska University Hospital in Flemingsberg (South Campus area).

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Preclinical Laboratory Portal

The Preclinical Laboratory (PKL) offers cryopreservation techniques and re-derivation services. Managed by the Karolinska University Hospital in Huddinge (South Campus area).

More about the PKL

Transgene Technologies

The Karolinska Center for Transgene Technologies (KCTT) offers generation and storage of genetically modified mice and related techniques. The KCTT facility is a part of Karolinska Institutet Mouse Models (KIMM).

More about the KCTT

Zebrafish Core Facility

The Zebrafish Core Facility provides researchers with fish from wildtype lines, as well as offer the possibility of bringing in mutant/transgenic fish lines of interest from other laboratories.

More about the Zebrafish facility

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