Animal experimental core facilities

Animal Behavior Core Facility

The Animal Behavior Core Facility (ABCF) is the new core facility at Karolinska Institutet for behavioral studies in mice and rats. ABCF is designed to provide optimal environment, state-of-the-art instrumentation and technical/educational support to perform behavioral tests ranging from basic phenotype characterization to advanced analyses. 

Import Portal

Generally, laboratory animals imported to animal facilities have to go through quarantine first due to unsure or unsatisfactory health status. The Import Portal – Portalen is a quarantine core-facility managed by Comparative Medicine (KM). 

Infinigene

Manipulation of gene expression during mouse development is a powerful tool for querying the role of specific genes in development and disease. The Infinigene core facility utilizes ultrasound-guided nano-injection to introduce DNA-modifying agents during embryonic development, or in adult mice. 

Karolinska Experimental Research and Imaging Centre

Karolinska Experimental Research and Imaging Centre (KERIC) conducts imaging analyses in experimental systems in combination with experimental surgery in large animals like swine as well as in rodents. This facility is managed by the Karolinska University Hospital in Solna (North Campus area). 

Morphological Phenotype Analysis Core Facility (FENO)

Morphological Phenotype Analysis Core Facility (FENO) facility specialises in the pathology of genetically engineered mice. This core facility is managed by the Karolinska University Hospital in Flemingsberg (South Campus area). 

Preclinical Laboratory (PKL) Portal South

Preclinical Laboratory (PKL) Portal South offers cryopreservation techniques and rederivation services in mouse lines, as well as support when it comes to arranging transport, various certificates and contacts with authorities of different countries to facilitate import and export. The facility is managed by the Preclinical Laboratory (PKL) at the Karolinska University Hospital, Huddinge (South Campus area). 

Transgene Technologies

The KCTT mouse transgenic core facility  offers generation and storage of genetically modified mice and related techniques. The KCTT facility is managed by Comparative Medicine (KM). 

X-ray Irradiation Core Facility – nodes KM

The X-ray Irradiation Core Facility – nodes KM is an X-ray cabinet for irradiation of small animals managed by Comparative Medicine, Karolinska Institutet. The cabinets can be used for whole body irradiation or focal irradiation. 

Zebrafish Core Facility

The Zebrafish Core Facility at Karolinska Institutet is the largest zebrafish facility in the Nordic countries. The core facility offers everything from the provision of animals, technical training to the running of complex research projects, and welcome both internal and external academic research groups, as well as non-academic customers. No previous experience with the zebrafish model needed.