Animal experimental core facilities
At Karolinska Institutet, the managing organisation for all aspects of animal experimentation in research is Comparative Medicine. Our scientists also have access to animal facilities managed by the Karolinska University Hospital.
Animal Behavior Core Facility (ABCF)
The Animal Behavior Core Facility (ABCF) is the new core facility at Karolinska Institutet for behavioral studies in mice and rats. ABCF is designed to provide optimal environment, state-of-the-art instrumentation and technical/educational support to perform behavioral tests ranging from basic phenotype characterization to advanced analyses.
Generally, laboratory animals imported to animal facilities have to go through quarantine first due to unsure or unsatisfactory health status. The Import Portal is a quarantine core-facility managed by Comparative Medicine (KM).
Manipulation of gene expression during mouse development is a powerful tool for querying the role of specific genes in development and disease. Infinigene is a facility which utilizes ultrasound-guided nano-injection to introduce DNA-modifying agents during embryonic development, or in adult mice.
Karolinska Experimental Research and Imaging Centre
Karolinska Experimental Research and Imaging Centre (KERIC) conducts Imaging analyses in experimental systems in combination with experimental surgery in large animals like swine as well as in rodents. This facility is managed by the Karolinska University Hospital in Solna (North Campus area).
KM X-ray irradiation facilities
This is an X-ray cabinet for irradiation of small animals managed by Comparative Medicine, Karolinska Institutet. The cabinets can be used for whole body irradiation or focal irradiation.
Morphological Phenotype Analysis
Morphological Phenotype Analysis (FENO) facility specialises in the pathology of genetically engineered mice. This core facility is managed by the Karolinska University Hospital in Flemingsberg (South Campus area).
Preclinical Laboratory Portal
The Preclinical Laboratory (PKL) offers cryopreservation techniques and re-derivation services. Managed by the Karolinska University Hospital in Huddinge (South Campus area).
Small Animal Molecular Imaging
The unit can offer multimodal (PET, CT, MRI) imaging measurements in rodents for studies related to for example: Radioligand development; Molecular imaging biomarker development; Drug development (microdosing, occupancy, etc.); Various molecular imaging experiments in translational animal models; Tracking of novel administration routes.
The Karolinska Center for Transgene Technologies (KCTT) offers generation and storage of genetically modified mice and related techniques. The KCTT facility is a part of Karolinska Institutet Mouse Models (KIMM).
Zebrafish Core Facility
The Zebrafish Core Facility provides researchers with fish from wildtype lines, as well as offer the possibility of bringing in mutant/transgenic fish lines of interest from other laboratories.
Comparative Medicine deals with all aspects of activities related to animal experimentation in research at Karolinska Institutet.
We also offer some of our services to other educational institutions or research laboratories in Sweden.
Book core-facility services in iLab
Do you know what services you are searching for? Login directly to the startpage of iLab booking system. Not all our core facilities are available in iLab, the system will be fully implemented in December 2021.
Single Point of Contact
Didn't you find what you where looking for or are you unsure about which core facility to contact about a specific tool or analytic method? The SPOC for research infrastructure can be of assistance. Please note: Researchers within KI and Region Stockholm have priority.