Kardiovaskulär Epidemiologi – Karin Leander forskargrupp

Vår forskning är inom området kardiovaskulär epidemiologi, med ett generellt syfte att öka kunskapen om kardiovaskulära riskfaktorer för att förbättra den vetenskapliga grunden för primär och sekundär prevention hos kvinnor och män. Vi studerar kardiometabolt relaterade faktorer såsom låggradig inflammation, blodfettsrubbningar, högt blodtryck och diabetes samt betydelsen av livsstilsfaktorer, såsom kostvanor, för den kardiovaskulära hälsan. Kvinnospecifika riskfaktorer ges särskilt fokus.

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Utvalda publikationer

Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2025;45(3):443-451
Circulating ANGPTL3/8 Concentrations Are Associated With an Atherogenic Lipoprotein Profile and Increased CHD Risk in Swedish Population-Based Studies
Leander K; Chen YQ; Vikstrom M; Silveira A; Fisher RM; Konrad RJ; van 't Hooft FM
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2024;13(17):e033648
Menopausal Vasomotor Symptoms and Subclinical Atherosclerotic Cardiovascular Disease: A Population-Based Study
Nilsson S; Qvick A; Henriksson M; Lawesson SS; Holm A-CS; Leander K
Article: CIRCULATION. 2024;149(4):305-316
Role of Polyunsaturated Fat in Modifying Cardiovascular Risk Associated With Family History of Cardiovascular Disease: Pooled De Novo Results From 15 Observational Studies
Laguzzi F; Akesson A; Marklund M; Qian F; Gigante B; Bartz TM; Bassett JK; Birukov A; Campos H; Hirakawa Y; Imamura F; Jaeger S; Lankinen M; Murphy RA; Senn M; Tanaka T; Tintle N; Virtanen JK; Yamagishi K; Allison M; Brouwer IA; De Faire U; Eiriksdottir G; Ferrucci L; Forouhi NG; Geleijnse JM; Hodge AM; Kimura H; Laakso M; Riserus U; van Westing AC; Bandinelli S; Baylin A; Giles GG; Gudnason V; Iso H; Lemaitre RN; Ninomiya T; Post WS; Psaty BM; Salonen JT; Schulze MB; Tsai MY; Uusitupa M; Wareham NJ; Oh S-W; Wood AC; Harris WS; Siscovick D; Mozaffarian D; Leander K
Article: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2023;16(3):236-247
Cross-Sectional Gene-Smoking Interaction Analysis in Relation to Subclinical Atherosclerosis-Results From the IMPROVE Study
Maitusong B; Laguzzi FJ; Strawbridge R; Baldassarre D; Veglia FE; Humphries S; Savonen K; Kurl S; Pirro MJ; Smit A; Giral P; Silveira A; Tremoli E; Hamsten A; de Faire U; Gigante B; Leander K
Article: EUROPEAN JOURNAL OF NUTRITION. 2021;60(1):123-134
Alcohol consumption in relation to carotid subclinical atherosclerosis and its progression: results from a European longitudinal multicentre study
Laguzzi F; Baldassarre D; Veglia F; Strawbridge RJ; Humphries SE; Rauramaa R; Smit AJ; Giral P; Silveira A; Tremoli E; Hamsten A; de Faire U; Frumento P; Leander K
Article: PLOS MEDICINE. 2017;14(11):e1002445
Postmenopausal hormone therapy and risk of stroke: A pooled analysis of data from population-based cohort studies
Carrasquilla GD; Frumento P; Berglund A; Borgfeldt C; Bottai M; Chiavenna C; Eliasson M; Engstrom G; Hallmans G; Jansson J-H; Magnusson PK; Nilsson PM; Pedersen NL; Wolk A; Leander K
Article: CIRCULATION. 2016;133(13):1230-1239
Circulating Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Predicts Future Risk of Cardiovascular Events Independently of Established Risk Factors
Leander K; Malarstig A; van't Hooft FM; Hyde C; Hellenius M-L; Troutt JS; Konrad RJ; Ohrvik J; Hamsten A; de Faire U