Lemmens Grupp

Publikationer

Utvalda publikationer

• Article: EMBO JOURNAL. 2025;44(23):7263-7294

  Spatial mapping of DNA synthesis reveals dynamics and geometry of human replication nanostructures

  Hawgood M; Urien B; Agostinho A; Thiagarajan P; Giglio G; Yang Y; Zhang X; Quijada G; Fonseca M; Bartek J; Blom H; Lemmens B
• Article: NATURE COMMUNICATIONS. 2025;16(1):8268

  Temporal control of human DNA replication licensing by CDK4/6-RB signalling and chemical genetics

  Sosenko Piscitello A; Nilsson A-S; Hawgood M; Sayyid AH; Dionellis VS; Giglio G; Urien B; Bajgain P; Ntallis SG; Bartek J; Halazonetis TD; Lemmens B
• Preprint: BIORXIV. 2025

  Spatial mapping of DNA synthesis reveals dynamics and geometry of human replication nanostructures

  Hawgood M; Urién González B; Agostinho A; Thiagarajan P; Yang Y; Zhang X; Giglio G; Quijada G; Fonseca M; Bartek J; Blom H; Lemmens B
• Article: JOURNAL OF MEDICINAL CHEMISTRY. 2024;67(11):8609-8629

  Novel Dihydropteridinone Derivatives As Potent Inhibitors of the Understudied Human Kinases Vaccinia-Related Kinase 1 and Casein Kinase 1δ/ε

  Gama FHDS; Dutra LA; Hawgood M; dos Reis CV; Serafim RAM; Ferreira Jr MA; Teodoro BVM; Takarada J; Santiago AS; Balourdas D-I; Nilsson A-S; Urien B; Almeida VM; Gileadi C; Ramos PZ; Salmazo A; Vasconcelos SNS; Cunha MR; Mueller S; Knapp S; Massirer KB; Elkins JM; Gileadi O; Mascarello A; Lemmens BBLG; Guimaraes CRW; Azevedo H; Counago RM
• Article: CELL DEATH AND DIFFERENTIATION. 2023;30(7):1666-1678

  Actionable cancer vulnerability due to translational arrest, p53 aggregation and ribosome biogenesis stress evoked by the disulfiram metabolite CuET

  Kanellis DC; Zisi A; Skrott Z; Lemmens B; Espinoza JA; Kosar M; Bjorkman A; Li X; Arampatzis S; Bartkova J; Andujar-Sanchez M; Fernandez-Capetillo O; Mistrik M; Lindstrom MS; Bartek J
• Article: NUCLEIC ACIDS RESEARCH. 2022;50(11):6235-6250

  THO complex deficiency impairs DNA double-strand break repair via the RNA surveillance kinase SMG-1

  Kamp JA; Lemmens BBLG; Romeijn RJ; Gonzalez-Prieto R; Olsen JV; Vertegaal ACO; van Schendel R; Tijsterman M
• Article: NATURE COMMUNICATIONS. 2021;12(1):7126

  Helicase Q promotes homology-driven DNA double-strand break repair and prevents tandem duplications

  Kamp JA; Lemmens BBLG; Romeijn RJ; Changoer SC; van Schendel R; Tijsterman M
• Review: JOURNAL OF CELL BIOLOGY. 2019;218(12):3892-3902

  DNA replication and mitotic entry: A brake model for cell cycle progression

  Lemmens B; Lindqvist A
• Article: MOLECULAR CELL. 2018;71(1):117-128.e3

  DNA Replication Determines Timing of Mitosis by Restricting CDK1 and PLK1 Activation

  Lemmens B; Hegarat N; Akopyan K; Sala-Gaston J; Bartek J; Hochegger H; Lindqvist A
• Article: NATURE COMMUNICATIONS. 2015;6:8909

  Mutagenic consequences of a single G-quadruplex demonstrate mitotic inheritance of DNA replication fork barriers

  Lemmens B; van Schendel R; Tijsterman M
• Article: PLOS GENETICS. 2013;9(3):e1003339

  A Role for the Malignant Brain Tumour (MBT) Domain Protein LIN-61 in DNA Double-Strand Break Repair by Homologous Recombination

  Johnson NM; Lemmens BBLG; Tijsterman M
• Article: PLOS GENETICS. 2013;9(2):e1003276

  COM-1 Promotes Homologous Recombination during Caenorhabditis elegans Meiosis by Antagonizing Ku-Mediated Non-Homologous End Joining

  Lemmens BBLG; Johnson NM; Tijsterman M
• Review: CHROMOSOMA. 2011;120(1):1-21

  DNA double-strand break repair in Caenorhabditis elegans

  Lemmens BBLG; Tijsterman M
• Article: CURRENT BIOLOGY. 2006;16(19):1950-1955

  Polo-like kinase-1 controls proteasome-dependent degradation of claspin during checkpoint recovery

  Mamely I; van Vugt MATM; Smits VAJ; Semple JI; Lemmens B; Perrakis A; Medema RH; Freire R

Medarbetare och kontakt

Gruppledare

• 

  Bennie Lemmens

  Forskare | Biträdande Lektor

  E-postadress bennie.lemmens@ki.se

Alla medarbetare i gruppen

• 

  Giovanni Giglio

  Doktorand

  E-postadress giovanni.giglio@ki.se
• Sunil Kumar Pradhan

  Postdoktor

  E-postadress sunil.pradhan@ki.se
• Nicole Schilder

  Forskningsassistent

  E-postadress nicole.schilder@ki.se
• Bruno Urien Gonzalez

  Doktorand-L

  E-postadress bruno.urien@ki.se
• Xue Zhang

  Postdoktor

  E-postadress xue.zhang@ki.se

Vår forskargrupp är en del av SciLifeLab

Foto: SciLifeLab

Vår forskargrupp är en del av SciLifeLab

SciLifeLab är ett nationellt samarbete mellan flera svenska lärosäten som samverkar med hälsovård, industri, myndigheter och internationella organisationer. Denna ledande nationella forskningsinfrastruktur och forskningsmiljö inom området molekylär biovetenskap tillhandahåller avancerade teknologier och expertis för grund- och tillämpad livsvetenskap.