Epigenetisk reglering av leukemi och normal blodutveckling – Andreas Lennartssons forskargrupp

Vi identifierar nyckelmekanismer som orsakar epigenetisk och transkriptionell störning i AML (akut myeloisk leukemi) för att kunna hitta nya sätt att behandla sjukdomen.

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För detaljerad information om vår forskning, se vår engelska sida.

Publikationer

Utvalda publikationer

  • Article: LEUKEMIA. 2023;37(9):1830-1841
    Palau A; Segerberg F; Lidschreiber M; Lidschreiber K; Naughton AJ; Needhamsen M; Jung LA; Jagodic M; Cramer P; Lehmann S; Carlsten M; Lennartsson A
  • Article: NUCLEIC ACIDS RESEARCH. 2023;51(D1):D564-D570
    Marakulina D; Vorontsov IE; Kulakovskiy IV; Lennartsson A; Drablos F; Medvedeva YA
  • Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022;23(19):11413
    Romanova EI; Zubritskiy AV; Lioznova AV; Ogunleye AJ; Golotin VA; Guts AA; Lennartsson A; Demidov ON; Medvedeva YA
  • Article: BLOOD ADVANCES. 2021;5(4):1003-1016
    Mareschal S; Palau A; Lindberg J; Ruminy P; Nilsson C; Bengtzen S; Engvall M; Eriksson A; Neddermeyer A; Marchand V; Jansson M; Bjorklund M; Jardin F; Rantalainen M; Lennartsson A; Cavelier L; Gronberg H; Lehmann S
  • Journal article: GENOME RESEARCH. 2020;30(9):1377
    Ramilowski JA; Yip CW; Agrawal S; Chang J-C; Ciani Y; Kulakovskiy IV; Mendez M; Ooi JLC; Ouyang JF; Parkinson N; Petri A; Roos L; Severin J; Yasuzawa K; Abugessaisa I; Akalin A; Antonov IV; Arner E; Bonetti A; Bono H; Borsari B; Brombacher F; Cameron CJF; Cannistraci CV; Cardenas R; Cardon M; Chang H; Dostie J; Ducoli L; Favorov A; Fort A; Garrido D; Gil N; Gimenez J; Guler R; Handoko L; Harshbarger J; Hasegawa A; Hasegawa Y; Hashimoto K; Hayatsu N; Heutink P; Hirose T; Imada EL; Itoh M; Kaczkowski B; Kanhere A; Kawabata E; Kawaji H; Kawashima T; Kelly ST; Kojima M; Kondo N; Koseki H; Kouno T; Kratz A; Kurowska-Stolarska M; Kwon ATJ; Leek J; Lennartsson A; Lizio M; Lopez-Redondo F; Luginbuhl J; Maeda S; Makeev VJ; Marchionni L; Medvedeva YA; Minoda A; Muller F; Munoz-Aguirre M; Murata M; Nishiyori H; Nitta KR; Noguchi S; Noro Y; Nurtdinov R; Okazaki Y; Orlando V; Paquette D; Parr CJC; Rackham OJL; Rizzu P; Martinez DFS; Sandelin A; Sanjana P; Semple CAM; Shibayama Y; Sivaraman DM; Suzuki T; Szumowski SC; Tagami M; Taylor MS; Terao C; Thodberg M; Thongjuea S; Tripathi V; Ulitsky I; Verardo R; Vorontsov IE; Yamamoto C; Young RS; Baillie JK; Forrest ARR; Guigo R; Hoffman MM; Hon CC; Kasukawa T; Kauppinen S; Kere J; Lenhard B; Schneider C; Suzuki H; Yagi K; de Hoon MJL; Shin JW; Carninci P
  • Article: BLOOD. 2020;136(3):339-352
    Mujahed H; Miliara S; Neddermeyer A; Bengtzen S; Nilsson C; Deneberg S; Cordeddu L; Ekwall K; Lennartsson A; Lehmann S
  • Article: EPIGENETICS. 2020;15(6-7):702-714
    Varnoosfaderani FS; Palau A; Dong W; Persson J; Durand-Dubief M; Svensson JP; Lennartsson A
  • Article: EXPERIMENTAL HEMATOLOGY. 2019;79:35-46.e1
    Scialdone A; Khazaei S; Hasni MS; Lennartsson A; Gullberg U; Drott K
  • Article: BLOOD. 2017;129(7):e13-e25
    Qu Y; Siggens L; Cordeddu L; Gaidzik VI; Karlsson K; Bullinger L; Doehner K; Ekwall K; Lehmann S; Lennartsson A
  • Article: EXPERIMENTAL HEMATOLOGY. 2015;43(8):609-624
    Eriksson A; Lennartsson A; Lehmann S
  • Article: SCIENCE. 2015;347(6225):1010-1014
    Arner E; Daub CO; Vitting-Seerup K; Andersson R; Lilje B; Drablos F; Lennartsson A; Roennerblad M; Hrydziuszko O; Vitezic M; Freeman TC; Alhendi AMN; Arner P; Axton R; Baillie JK; Beckhouse A; Bodega B; Briggs J; Brombacher F; Davis M; Detmar M; Ehrlund A; Endoh M; Eslami A; Fagiolini M; Fairbairn L; Faulkner GJ; Ferrai C; Fisher ME; Forrester L; Goldowitz D; Guler R; Ha T; Hara M; Herlyn M; Ikawa T; Kai C; Kawamoto H; Khachigian LM; Klinken SP; Kojima S; Koseki H; Klein S; Mejhert N; Miyaguchi K; Mizuno Y; Morimoto M; Morris KJ; Mummery C; Nakachi Y; Ogishima S; Okada-Hatakeyama M; Okazaki Y; Orlando V; Ovchinnikov D; Passier R; Patrikakis M; Pombo A; Qin X-Y; Roy S; Sato H; Savvi S; Saxena A; Schwegmann A; Sugiyama D; Swoboda R; Tanaka H; Tomoiu A; Winteringham LN; Wolvetang E; Yanagi-Mizuochi C; Yoneda M; Zabierowski S; Zhang P; Abugessaisa I; Bertin N; Diehl AD; Fukuda S; Furuno M; Harshbarger J; Hasegawa A; Hori F; Ishikawa-Kato S; Ishizu Y; Itoh M; Kawashima T; Kojima M; Kondo N; Lizio M; Meehan TF; Mungall CJ; Murata M; Nishiyori-Sueki H; Sahin S; Nagao-Sato S; Severin J; de Hoon MJL; Kawai J; Kasukawa T; Lassmann T; Suzuki H; Kawaji H; Summers KM; Wells C; Hume DA; Forrest ARR; Sandelin A; Carninci P; Hayashizaki Y
  • Article: EPIGENETICS & CHROMATIN. 2015;8(1):4
    Siggens L; Cordeddu L; Rnnerblad M; Lennartsson A; Ekwall K
  • Article: EPIGENETICS. 2014;9(8):1108-1119
    Qu Y; Lennartsson A; Gaidzik VI; Deneberg S; Karimi M; Bengtzen S; Hoglund M; Bullinger L; Doehner K; Lehmann S
  • Article: BLOOD. 2014;123(17):e79-e89
    Ronnerblad M; Andersson R; Olofsson T; Douagi I; Karimi M; Lehmann S; Hoof I; de Hoon M; Itoh M; Nagao-Sato S; Kawaji H; Lassmann T; Carninci P; Hayashizaki Y; Forrest ARR; Sandelin A; Ekwall K; Arner E; Lennartsson A
  • Article: BLOOD. 2014;123(17):e46-e57
    Prasad P; Ronnerblad M; Arner E; Itoh M; Kawaji H; Lassmann T; Daub CO; Forrest ARR; Lennartsson A; Ekwall K
  • Article: NATURE. 2014;507(7493):462-470
    Forrest ARR; Kawaji H; Rehli M; Baillie JK; de Hoon MJL; Haberle V; Lassmann T; Kulakovskiy IV; Lizio M; Itoh M; Andersson R; Mungall CJ; Meehan TF; Schmeier S; Bertin N; Jorgensen M; Dimont E; Arner E; Schmidl C; Schaefer U; Medvedeva YA; Plessy C; Vitezic M; Severin J; Semple CA; Ishizu Y; Young RS; Francescatto M; Alam I; Albanese D; Altschuler GM; Arakawa T; Archer JAC; Arner P; Babina M; Rennie S; Balwierz PJ; Beckhouse AG; Pradhan-Bhatt S; Blake JA; Blumenthal A; Bodega B; Bonetti A; Briggs J; Brombacher F; Burroughs AM; Califano A; Cannistraci CV; Carbajo D; Chen Y; Chierici M; Ciani Y; Clevers HC; Dalla E; Davis CA; Detmar M; Diehl AD; Dohi T; Drablos F; Edge ASB; Edinger M; Ekwall K; Endoh M; Enomoto H; Fagiolini M; Fairbairn L; Fang H; Farach-Carson MC; Faulkner GJ; Favorov AV; Fisher ME; Frith MC; Fujita R; Fukuda S; Furlanello C; Furuno M; Furusawa J-I; Geijtenbeek TB; Gibson AP; Gingeras T; Goldowitz D; Gough J; Guhl S; Guler R; Gustincich S; Ha TJ; Hamaguchi M; Hara M; Harbers M; Harshbarger J; Hasegawa A; Hasegawa Y; Hashimoto T; Herlyn M; Hitchens KJ; Sui SJH; Hofmann OM; Hoof I; Hori F; Huminiecki L; Iida K; Ikawa T; Jankovic BR; Jia H; Joshi A; Jurman G; Kaczkowski B; Kai C; Kaida K; Kaiho A; Kajiyama K; Kanamori-Katayama M; Kasianov A; Kasukawa T; Katayama S; Kato S; Kawaguchi S; Kawamoto H; Kawamura YI; Kawashima T; Kempfle JS; Kenna TJ; Kere J; Khachigian LM; Kitamura T; Klinken SP; Knox AJ; Kojima M; Kojima S; Kondo N; Koseki H; Koyasu S; Krampitz S; Kubosaki A; Kwon AT; Laros JFJ; Lee W; Lennartsson A; Li K; Lilje B; Lipovich L; Mackay-sim A; Manabe R-I; Mar JC; Marchand B; Mathelier A; Mejhert N; Meynert A; Mizuno Y; Morais DADL; Morikawa H; Morimoto M; Moro K; Motakis E; Motohashi H; Mummery CL; Murata M; Nagao-Sato S; Nakachi Y; Nakahara F; Nakamura T; Nakamura Y; Nakazato K; Van Nimwegen E; Ninomiya N; Nishiyori H; Noma S; Nozaki T; Ogishima S; Ohkura N; Ohmiya H; Ohno H; Ohshima M; Okada-Hatakeyama M; Okazaki Y; Orlando V; Ovchinnikov DA; Pain A; Passier R; Patrikakis M; Persson H; Piazza S; Prendergast JGD; Rackham OJL; Ramilowski JA; Rashid M; Ravasi T; Rizzu P; Roncador M; Roy S; Rye MB; Saijyo E; Sajantila A; Saka A; Sakaguchi S; Sakai M; Sato H; Satoh H; Savvi S; Saxena A; Schneider C; Schultes EA; Schulze-Tanzil GG; Schwegmann A; Sengstag T; Sheng G; Shimoji H; Shimoni Y; Shin JW; Simon C; Sugiyama D; Sugiyama T; Suzuki M; Suzuki N; Swoboda RK; 't Hoen PAC; Tagami M; Takahashi N; Takai J; Tanaka H; Tatsukawa H; Tatum Z; Thompson M; Toyoda H; Toyoda T; Valen E; van de Wetering M; van den Berg LM; Verardo R; Vijayan D; Vorontsov IE; Wasserman WW; Watanabe S; Wells CA; Winteringham LN; Wolvetang E; Wood EJ; Yamaguchi Y; Yamamoto M; Yoneda M; Yonekura Y; Yoshida S; Zabierowski SE; Zhang PG; Zhao X; Zucchelli S; Summers KM; Suzuki H; Daub CO; Kawai J; Heutink P; Hide W; Freeman TC; Lenhard B; Bajic VB; Taylor MS; Makeev VJ; Sandelin A; Hume DA; Carninci P; Hayashizaki Y
  • Article: NATURE. 2014;507(7493):455-461
    Andersson R; Gebhard C; Miguel-Escalada I; Hoof I; Bornholdt J; Boyd M; Chen Y; Zhao X; Schmidl C; Suzuki T; Ntini E; Arner E; Valen E; Li K; Schwarzfischer L; Glatz D; Raithel J; Lilje B; Rapin N; Bagger FO; Jorgensen M; Andersen PR; Bertin N; Rackham O; Burroughs AM; Baillie JK; Ishizu Y; Shimizu Y; Furuhata E; Maeda S; Negishi Y; Mungall CJ; Meehan TF; Lassmann T; Itoh M; Kawaji H; Kondo N; Kawai J; Lennartsson A; Daub CO; Heutink P; Hume DA; Jensen TH; Suzuki H; Hayashizaki Y; Mueller F; Forrest ARR; Carninci P; Rehli M; Sandelin A

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