Genetiska mekanismer för åldrande – Maria Erikssons forskargrupp

Publikationer

Utvalda publikationer

• Journal article: NATURE AGING. 2026;6(7):1354-1357

  Reaching for the cure as progeria research comes of age at the 12th international scientific workshop

  Eriksson M; Andres V; Kieran MW; Gordon LB
• Article: NATURE AGING. 2025;5(9):1739-1749

  Induced somatic mutation accumulation during skeletal muscle regeneration reduces muscle strength

  Vrtacnik P; Merino LG; Subhash S; Helgadottir HT; Bardin M; Stefani F; Wang D; Chen P; Franco I; Revechon G; Eriksson M
• Article: NATURE AGING. 2025;5(6):1046-1062

  Recurrent somatic mutation and progerin expression in early vascular aging of chronic kidney disease

  Revechon G; Witasp A; Viceconte N; Helgadottir HT; Machtel P; Stefani F; Whisenant D; Sola-Carvajal A; McGuinness D; Abutaleb NO; Artiach G; Arzt EW; Soveri I; Babler A; Ziegler S; Kramann R; Back M; Thorell A; Truskey GA; Wennberg L; Shiels PG; Wernerson A; Stenvinkel P; Eriksson M
• Article: EUROPEAN HEART JOURNAL. 2023;44(40):4208-4210

  Somatic mutations in vascular wall function and age-associated disease.

  Revêchon G; Merino LG; Machtel P; Eriksson M
• Editorial: CIRCULATION. 2023;147(23):1745-1747

  Readily Available Tools to Detect Progerin and Cardiac Disease Progression in Hutchinson-Gilford Progeria Syndrome

  Eriksson M; Haugaa K; Revechon G
• Article: NATURE COMMUNICATIONS. 2022;13(1):6834

  The Heterochromatin protein 1 is a regulator in RNA splicing precision deficient in ulcerative colitis

  Mata-Garrido J; Xiang Y; Chang-Marchand Y; Reisacher C; Ageron E; Guerrera IC; Casafont I; Bruneau A; Cherbuy C; Treton X; Dumay A; Ogier-Denis E; Batsche E; Costallat M; Revechon G; Eriksson M; Muchardt C; Arbibe L
• Editorial: NATURE REVIEWS GENETICS. 2022;23(11):645-646

  Reverting to old theories of ageing with new evidence for the role of somatic mutations

  Franco I; Eriksson M
• Article: NATURE COMMUNICATIONS. 2022;13(1):3068

  Transient expression of an adenine base editor corrects the Hutchinson-Gilford progeria syndrome mutation and improves the skin phenotype in mice

  Whisenant D; Lim K; Revechon G; Yao H; Bergo MO; Machtel P; Kim J-S; Eriksson M
• Editorial: AGING CELL. 2022;21(5):e13613

  Challenges of proving a causal role of somatic mutations in the aging process

  Franco I; Revechon G; Eriksson M
• Editorial: NEW ENGLAND JOURNAL OF MEDICINE. 2021;384(14):1364-1366

  Base Editing in Progeria

  Kim J-S; Eriksson M
• Editorial: NATURE MEDICINE. 2021;27(3):377-379

  Splice-inhibition therapy targets progeria

  Revechon G; Whisenant D; Eriksson M
• Article: GENOME BIOLOGY. 2019;20(1):285

  Whole genome DNA sequencing provides an atlas of somatic mutagenesis in healthy human cells and identifies a tumor-prone cell type

  Franco I; Helgadottir HT; Moggio A; Larsson M; Vrtacnik P; Johansson A; Norgren N; Lundin P; Mas-Ponte D; Nordstrom J; Lundgren T; Stenvinkel P; Wennberg L; Supek F; Eriksson M
• Article: AGING CELL. 2019;18(6):e13010

  Analysis of somatic mutations identifies signs of selection during in vitro aging of primary dermal fibroblasts

  Narisu N; Rothwell R; Vrtacnik P; Rodriguez S; Didion J; Zollner S; Erdos MR; Collins FS; Eriksson M
• Article: NATURE COMMUNICATIONS. 2019;10(1):4990

  Inhibition of DNA damage response at telomeres improves the detrimental phenotypes of Hutchinson-Gilford Progeria Syndrome

  Aguado J; Sola-Carvajal A; Cancila V; Revechon G; Ong PF; Jones-Weinert CW; Arzt EW; Lattanzi G; Dreesen O; Tripodo C; Rossiello F; Eriksson M; di Fagagna FD
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2019;139(11):2272-2280.e12

  Accumulation of Progerin Affects the Symmetry of Cell Division and Is Associated with Impaired Wnt Signaling and the Mislocalization of Nuclear Envelope Proteins

  Sola-Carvajal A; Revechon G; Helgadottir HT; Whisenant D; Hagblom R; Dohla J; Katajisto P; Brodin D; Fagerstrom-Billai F; Viceconte N; Eriksson M
• Article: HUMAN MOLECULAR GENETICS. 2019;28(16):2675-2685

  Somatic mutation that affects transcription factor binding upstream of CD55 in the temporal cortex of a late-onset Alzheimer disease patient

  Helgadottir H; Lundin P; Arzt EW; Lindstrom A-K; Graff C; Eriksson M
• Article: JOURNAL OF CLINICAL INVESTIGATION. 2019;129(2):531-545

  Endothelial progerin expression causes cardiovascular pathology through an impaired mechanoresponse

  Osmanagic-Myers S; Kiss A; Manakanatas C; Hamza O; Sedlmayer F; Szabo PL; Fischer I; Fichtinger P; Podesser BK; Eriksson M; Foisner R
• Article: NATURE COMMUNICATIONS. 2018;9(1):800

  Somatic mutagenesis in satellite cells associates with human skeletal muscle aging

  Franco I; Johansson A; Olsson K; Vrtacnik P; Lundin P; Helgadottir HT; Larsson M; Revechon G; Bosia C; Pagnani A; Provero P; Gustafsson T; Fischer H; Eriksson M
• Review: BIOCHEMICAL SOCIETY TRANSACTIONS. 2017;45(6):1279-1293

  Emerging candidate treatment strategies for Hutchinson-Gilford progeria syndrome

  Strandgren C; Revechon G; Sola-Carvajal A; Eriksson M
• Article: SCIENTIFIC REPORTS. 2017;7(1):4405

  Rare progerin-expressing preadipocytes and adipocytes contribute to tissue depletion over time

  Revechon G; Viceconte N; McKenna T; Sola-Carvajal A; Vrtacnik P; Stenvinkel P; Lundgren T; Hultenby K; Franco I; Eriksson M

Medarbetare och kontakt

Gruppledare

• 

  Maria Eriksson

  Professor | Docent

  E-postadress maria.eriksson.2@ki.se

Alla medarbetare i gruppen

• 

  Matthieu Robert René Bardin

  Postdoktor

  E-postadress matthieu.bardin@ki.se
• 

  Lara Garcia Merino

  Anknuten till Forskning

  E-postadress lara.garcia.merino@ki.se
• 

  Gwladys Revêchon

  Anknuten till Forskning

  E-postadress gwladys.revechon@ki.se
• 

  Fabiana Stefani

  Doktorand

  E-postadress fabiana.stefani@ki.se
• 

  Charlotte Strandgren

  Forskningsspecialist

  E-postadress charlotte.strandgren@ki.se
• Martin Wohlwend

  Biträdande Lektor

  Telefon +46852481239

  E-postadress martin.wohlwend@ki.se
• 

  Yiqi Zhang

  Doktorand

  E-postadress yiqi.zhang@ki.se