Neurobiologi vid stress och behandlingsreaktioner – Juan Pablo Lopez forskargrupp

Publikationer

Utvalda publikationer

• Article: CELL REPORTS. 2023;42(8):112874

  Sex shapes cell-type-specific transcriptional signatures of stress exposure in the mouse hypothalamus

  Brivio E; Kos A; Ulivi AF; Karamihalev S; Ressle A; Stoffel R; Hirsch D; Stelzer G; Schmidt MV; Lopez JP; Chen A
• Article: STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS. 2023;26(1):2186141

  Increasing resolution in stress neurobiology: from single cells to complex group behaviors

  Miranda L; Bordes J; Gasperoni S; Lopez JP
• Article: NEURON. 2022;110(14):2283-2298.e9

  Ketamine exerts its sustained antidepressant effects via cell-type-specific regulation of Kcnq2

  Lopez JP; Luecken MD; Brivio E; Karamihalev S; Kos A; De Donno C; Benjamin A; Yang H; Dick ALW; Stoffel R; Flachskamm C; Ressle A; Roeh S; Huettl R-E; Parl A; Eggert C; Novak B; Yan Y; Yeoh K; Holzapfel M; Hauger B; Harbich D; Schmid B; Di Giaimo R; Turck CW; Schmidt MV; Deussing JM; Eder M; Dine J; Theis FJ; Chen A
• Article: SCIENCE ADVANCES. 2021;7(5):eabe4497

  Single-cell molecular profiling of all three components of the HPA axis reveals adrenal ABCB1 as a regulator of stress adaptation

  Lopez JP; Brivio E; Santambrogio A; De Donno C; Kos A; Peters M; Rost N; Czamara D; Brueckl TM; Roeh S; Poehlmann ML; Engelhardt C; Ressle A; Stoffel R; Tontsch A; Villamizar JM; Reincke M; Riester A; Sbiera S; Fassnacht M; Mayberg HS; Craighead WE; Dunlop BW; Nemeroff CB; Schmidt MV; Binder EB; Theis FJ; Beuschlein F; Andoniadou CL; Chen A
• Review: GENES BRAIN AND BEHAVIOR. 2020;19(3):e12643

  Sex differences: Transcriptional signatures of stress exposure in male and female brains

  Brivio E; Lopez JP; Chen A
• Editorial: STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS. 2018;21(5):384-388

  Preclinical stress research: where are we headed? An early career investigator's perspective

  Gururajan A; Kos A; Lopez JP
• Review: CURRENT OPINION IN PSYCHIATRY. 2018;31(1):7-16

  Major depression and its treatment: microRNAs as peripheral biomarkers of diagnosis and treatment response

  Lopez JP; Kos A; Turecki G
• Letter: MOLECULAR PSYCHIATRY. 2017;22(9):1228-1229

  Dysregulation of the glutamatergic receptors after antidepressant treatment in human neural progenitor cells

  Cruceanu C; Lopez JP; Tsai W-T; Turecki G
• Article: NEUROPSYCHOPHARMACOLOGY. 2017;42(10):2043-2051

  Co-Variation of Peripheral Levels of miR-1202 and Brain Activity and Connectivity During Antidepressant Treatment

  Lopez JP; Pereira F; Richard-Devantoy S; Berlim M; Chachamovich E; Fiori LM; Niola P; Turecki G; Jollant F
• Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2017;20(8):619-623

  Investigation of miR-1202, miR-135a, and miR-16 in Major Depressive Disorder and Antidepressant Response

  Fiori LM; Lopez JP; Richard-Devantoy S; Berlim M; Chachamovich E; Jollant F; Foster J; Rotzinger S; Kennedy SH; Turecki G
• Article: NATURE COMMUNICATIONS. 2017;8:15497

  MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes

  Lopez JP; Fiori LM; Cruceanu C; Lin R; Labonte B; Cates HM; Heller EA; Vialou V; Ku SM; Gerald C; Han M-H; Foster J; Frey BN; Soares CN; Muller DJ; Farzan F; Leri F; MacQueen GM; Feilotter H; Tyryshkin K; Evans KR; Giacobbe P; Blier P; Lam RW; Milev R; Parikh SV; Rotzinger S; Strother SC; Lewis CM; Aitchison KJ; Wittenberg GM; Mechawar N; Nestler EJ; Uher R; Kennedy SH; Turecki G
• Article: BIOLOGICAL PSYCHIATRY. 2017;81(4):306-315

  DCC Confers Susceptibility to Depression-like Behaviors in Humans and Mice and Is Regulated by miR-218

  Torres-Berrio A; Lopez JP; Bagot RC; Nouel D; Dal Bo G; Cuesta S; Zhu L; Manitt C; Eng C; Cooper HM; Storch K-F; Turecki G; Nestler EJ; Flores C
• Article: BMC MEDICAL GENOMICS. 2015;8:35

  Biomarker discovery: quantification of microRNAs and other small non-coding RNAs using next generation sequencing

  Lopez JP; Diallo A; Cruceanu C; Fiori LM; Laboissiere S; Guillet I; Fontaine J; Ragoussis J; Benes V; Turecki G; Ernst C
• Article: NATURE MEDICINE. 2014;20(7):764-768

  miR-1202 is a primate-specific and brain-enriched microRNA involved in major depression and antidepressant treatment

  Lopez JP; Lim R; Cruceanu C; Crapper L; Fasano C; Labonte B; Maussion G; Yang JP; Yerko V; Vigneault E; El Mestikawy S; Mechawar N; Pavlidis P; Turecki G
• Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2014;17(1):23-32

  Regulatory role of miRNAs in polyamine gene expression in the prefrontal cortex of depressed suicide completers

  Lopez JP; Fiori LM; Gross JA; Labonte B; Yerko V; Mechawar N; Turecki G
• Letter: MOLECULAR PSYCHIATRY. 2013;18(4):398-399

  Epigenetic regulation of BDNF expression according to antidepressant response

  Lopez JP; Mamdani F; Labonte B; Beaulieu M-M; Yang JP; Berlim MT; Ernst C; Turecki G

Medarbetare och kontakt

Gruppledare

• 

  Juan Pablo Lopez

  Biträdande Lektor

  E-postadress jpablo.lopez@ki.se

Alla medarbetare i gruppen

• Tommaso Biagini

  Postdoktorala Studier

  E-postadress tommaso.biagini@ki.se
• 

  Paula Aldana Fontanet

  Forskningsspecialist

  E-postadress paula.fontanet@ki.se
• 

  Serena Gasperoni

  Doktorand

  E-postadress serena.gasperoni@ki.se
• 

  Xiuqi Ji

  Doktorand

  E-postadress xiuqi.ji@ki.se
• 

  Nicole Sabouné

  Doktorand

  E-postadress nicole.saboune@ki.se
• 

  Kelli Somelar-Duracz

  Postdoktor

  E-postadress kelli.somelarduracz@ki.se
• 

  Kristian Verdhi

  Forskningsassistent

  E-postadress kristian.verdhi@ki.se