SRP Diabetes supported Spatial Transcriptomics
SRP Diabetes has, together with three other strategic research areas (SFOs) funded instruments for spatial transcriptomics at existing core facilities. One is the Vizgen MERSCOPE at BIC, KI Solna.
Vizgen MERSCOPE Spatial transcriptomics
MERSCOPE from Vizgen is a specialized imaging system designed for spatial transcriptomics imaging, driven by MERFISH (Multiplexed Error-Robust Fluorescence in situ Hybridization) technology. MERFISH technology is built upon an RNA imaging-based technique called single molecule FISH and combinatorial barcoding scheme. This technique identifies nucleic acids in their native tissue environment with sub-cellular resolution.