Social Factors in Incidence And survival from childhood cancer (SOFIA)

Previous research indicates that socioeconomic differences in childhood cancer risk and survival may occur in Sweden and other Nordic countries, but the findings are inconsistent, as they are based on small numbers, and several specific cancer types have not been analyzed at all.

The overall aim of this research project is to assess how socioeconomic position and other social and family factors are related to childhood cancer in the Nordic countries (Sweden, Denmark, and Finland), in terms of both disease risk and survival after diagnosis. The goal is to determine if socioeconomic differences in disease risk and outcome exist, and if so, elucidate causal pathways as potential targets for preventive measures to reduce cancer incidence to the lowest level possible, and to give all children an equal chance to a continued life after childhood cancer diagnosis.

To evaluate the effect of different socioeconomic factors on childhood cancer risk and survival, a case-control study based on all childhood cancer cases diagnosed in Sweden, Denmark, and Finland will be created. Data from the high-quality cancer registers and other health care registers from these Nordics countries, together with childhood cancer registers and administrative registers on socioeconomic factors from Statistics Denmark, Finland and Sweden will be used for this Nordic collaborative project.

Collaborators

Ole Raaschou-Nielsen: Work, Environment and Cancer Research Group, Danish Cancer Society Research Center, Copenhagen, Denmark

Friederike Erdmann: Division of Childhood Cancer Epidemiology, Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center of the Johannes Gutenberg University Mainz, Germany, former at the Danish Cancer Society Research Center

Nea Malila: the Finnish Cancer Registry, Helsinki, Finland

Financing

FORTE

The Danish Childhood Cancer Foundation

Giorgio Tettamanti

Forskarassistent