Genomic Science and RNA Biology – Vicent Pelechano group
Understanding why identical cells respond differently to the same stimulus is a key challenge in biology. Clonal cells with identical genomes can still exhibit diverse behaviors. To study this, we use advanced genomic technologies to explore gene expression differences in clonal populations, focusing on post-transcriptional RNA regulation and the interplay between RNA decay and translation. Additionally, we are developing new molecular diagnostic tools for infectious diseases.
Vicente Pelechano Garcia
Principal ResearcherQuantitative Biology of the Nucleus – Magda Bienko Group
Our research interest lies in chromosome organization and its influence on gene expression.
Magda Bienko
Principal ResearcherRegulatory Transcriptomics – Kutter group
Research in our group focuses on identifiying and characterizing the regulatory interdependencies of protein-coding and noncoding RNAs (long noncoding, transfer and small RNAs) transcriptome-wide in mammalian somatic tissues and in the germline. Our goal is to gain mechanistic insights into the transcriptional and post-transcriptional regulation and processing of RNAs during organ development, cell differentiation and disease progression.