Postdoc Fellowships 2024 - Project 1
Project title: Early-onset type 2 diabetes, nationwide investigation of etiology and prognosis.
Summary
A rise in early-onset (age <40) type 2 diabetes has raised concerns due to its aggressive nature and poor prognosis. This project will address critical knowledge gaps regarding the causes and consequences of early-onset type 2 diabetes. It is based on a cohort consisting of the entire Swedish population with linkages between relatives and information from nationwide registers covering a 30-year time span together with biobank data for a subset. The project combines traditional cohort designs with family-based designs to minimize confounding and for familial aggregation and heritability studies. The goal is to be able to identify high risk individuals and key factors contributing to poor prognosis to improve primary and secondary prevention. To our knowledge, this is the most comprehensive research effort on early-onset type 2 diabetes to date and the post doc will play a key role in its realisation.