Sofia Carlsson
I am an epidemiologist with a strong interest in LADA (latent autoimmune diabetes in adults), adult-onset type 1 diabetes, and early-onset type 2 diabetes. My research aims to expand knowledge on the
About me
My research aims to expand knowledge on the causes and consequences of diabetes, with a particular focus on understudied forms such as LADA (latent autoimmune diabetes in adults), adult-onset type 1 diabetes, and early-onset type 2 diabetes.
Research
My work aims to expand knowledge on causes and consequences of autoimmune diabetes in adults including both LADA and type 1 diabetes and early-onset type 2 diabetes. An important cornerstone of this work is the ESTRID study (epidemiological study of risk factors for LADA-latent autoimmune diabetes in adults and type 2 diabetes) https://ki.se/en/imm/research/units-at-imm/unit-of-epidemiology/estrid, an ongoing multicenter study conducted at IMM. ESTRID is the largest and most detailed study of LADA to date and will provide unique opportunities to study the influence of both environmental and genetic factors on the disease onset and prognosis.
We also use nationwide register data and combine traditional cohort designs with family-based designs to strengthen causal inference. The overall aim of my research is to identify modifiable risk factors that can be used to prevent LADA, type 1 diabetes and early-onset type 2 diabetes and factors contributing to poor prognosis to inform secondary prevention.
Teaching
I have more than 15 years of experience teaching epidemiological methods (over 1, 000 teaching hours) at Karolinska Institutet, at both undergraduate and postgraduate levels. I served as course leader for a five-week course in Epidemiological methods within the Master’s Programme in Public Health at KI from 2013 to 2022.
Articles
- Article: JOURNAL OF AUTOIMMUNITY. 2026;161:103576Sorgjerd EP; Hals IK; Lonnum BEE; Edstorp J; Ahlqvist E; Carlsson S; Grill V
- Article: NPJ PARKINSONS DISEASE. 2026;12(1):127Vincze K; Szwajda A; Ploner A; Karlsson R; Kang X; Tang B; Qin C; Domenighetti C; Sugier P-E; Ashok Kumar Sreelatha A; Schulte C; Portugal B; May P; Bobbili DR; Radivojkov-Blagojevic M; Lichtner P; Singleton AB; Hernandez DG; Edsall C; Mellick GD; Zimprich A; Pirker W; Rogaeva E; Lang AE; Koks S; Taba P; Lesage S; Brice A; Corvol J-C; Chartier-Harlin M-C; Mutez E; Brockmann K; Deutschlander AB; Burbulla LF; Hadjigeorgiou GM; Dardiotis E; Stefanis L; Simitsi AM; Valente EM; Petrucci S; Straniero L; Zecchinelli A; Pezzoli G; Brighina L; Ferrarese C; Annesi G; Quattrone A; Gagliardi M; Matsuo H; Nakayama A; Hattori N; Nishioka K; Chung SJ; Kim YJ; Kolber P; van de Warrenburg BPC; Bloem BR; Toft M; Pihlstrom L; Correia Guedes L; Ferreira JJ; Bardien S; Carr J; Tolosa E; Ezquerra M; Pastor P; Ran C; Belin AC; Puschmann A; Clarke CE; Morrison KE; Tan M; Krainc D; Farrer MJ; Landoulsi Z; Kruger R; Gasser T; Elbaz A; Sharma M; Pedersen NL; Carlsson S; Hagg S; Wirdefeldt K
- Article: DIABETOLOGIA. 2026;69(5):1226-1236Lampousi A-M; Zeng J; Lofvenborg JE; Carlsson S; Ludvigsson J
- Article: CANCERS. 2026;18(9):1428Zhang Z; Carlsson S; Hammar N; Acedo P; Russell B; Kordasti S; Sarker D; Hemelrijck MV; Santaolalla A
- Article: LANCET DIABETES & ENDOCRINOLOGY. 2026;14(3):223-232Bjarko VV; Wolford BN; Haug EB; Stene LC; Carlsson S; Langhammer A; Birkeland KI; Berg TJ; Sorgjerd EP; Lyssenko V; Brumpton BM; Vie GA; Asvold BO
- Article: METABOLOGIA. 2026;2(1):2Keysendal E; Carlsson S; Lampousi A-M; Hampe CS; Huerta JM; Kerrison N; Nilsson PM; Pala V; Schulze MB; Sharp SJ; Rolandsson O; Wareham NJ
- Article: EUROPEAN JOURNAL OF PUBLIC HEALTH. 2025;35(6):1258-1263Carlsson S; Andersson T; Jansson S; Nystrom T; Rolandsson O; Wei Y
- Article: CELL REPORTS MEDICINE. 2025;6(11):102454Zhao A; Wei Y; Kontidou E; Mahdi A; Jannig PR; Torstensson S; Jiang H; Larsson A; Collado A; Humoud R; Grunler J; Ersga D; Esen BO; Zheng X; Lu H; Lindgren E; Risal S; Zhao J; Stener-Victorin E; Sorensen HT; Pedersen L; Pernow J; Zhou Z; Carlsson S; Catrina S-B; Deng Q
- Article: CLINICAL NUTRITION. 2025;54:153-161Lampousi A-M; Ahlqvist E; Alfredsson L; Edstorp J; Di Giuseppe D; Grill V; Lofvenborg JE; Padyukov L; Tuomi T; Asvold BO; Carlsson S
- Article: EUROPEAN HEART JOURNAL. 2025;46(38):3776-3786Wei Y; Andersson T; Tuomi T; Nystrom T; Carlsson S
- Article: DIABETIC MEDICINE. 2025;42(10):e70106Riise HKR; Haugstvedt A; Igland J; Wilhelmsen-Langeland A; Softeland E; Hermann M; Carlsson S; Skinner TC; Asvold BO; Iversen MM
- Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2025;40(7):845-857Amadou C; Wei Y; Tuomi T; Feychting M; Carlsson S
- Article: NATURE COMMUNICATIONS. 2025;16(1):5327Wei Y; Andersson T; Liu S; Feychting M; Kuja-Halkola R; Carlsson S
- Article: NEUROLOGY. 2025;104(5):e213372Tomson T; Andersson T; Carlsson S; Sveinsson O
- Article: DIABETOLOGY & METABOLIC SYNDROME. 2025;17(1):62Riise HKR; Haugstvedt A; Igland J; Graue M; Softeland E; Hermann M; Carlsson S; Skinner TC; Asvold BO; Iversen MM
- Article: DIABETOLOGIA. 2025;68(2):331-341Santoso C; Wei Y; Ahlqvist E; Tuomi T; Carlsson S
- Article: DIABETOLOGIA. 2025;68(1):69-81Edstorp J; Rossides M; Ahlqvist E; Alfredsson L; Askling J; Di Giuseppe D; Grill V; Sorgjerd EP; Tuomi T; Asvold BO; Carlsson S
- Article: EPILEPSY & BEHAVIOR. 2024;161:110106Melin S; Tomson T; Sveinsson O; Andersson T; Carlsson S; Ruck C; Wirdefeldt K
- Article: BMJ OPEN DIABETES RESEARCH & CARE. 2024;12(6):e004493Bjarko VV; Haug EB; Langhammer A; Ruiz PL-D; Carlsson S; Birkeland KI; Berg TJ; Sorgjerd EP; Lyssenko V; Asvold BO
- Article: LANCET REGIONAL HEALTH-EUROPE. 2024;46:101056Sun J; Yao J; Olen O; Halfvarsson J; Bergman D; Ebrahimi F; Carlsson S; Ludvigsson J; Ludvigsson JF
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All other publications
- Review: DIABETOLOGIA. 2026;:1-17Stener-Victorin E; Carlsson S; Hagstrom H; Taebnia N
- Review: SCANDINAVIAN JOURNAL OF PUBLIC HEALTH. 2025;:14034948251391690Carlsson S; Beck M; Bergstrom A; Dreij K; Ganguly K; Kippler M; Laguzzi F; Leander K; Lu D; Palmberg L; Upadhyay S; Zettergren A; Pershagen G
- Conference publication: DIABETOLOGIA. 2025;68:S4Wei Y; Nystrom T; Andersson T; Misra S; Tuomi T; Carlsson S
- Conference publication: DIABETOLOGIA. 2025;68:S186-S187Keysendal E; Ahlqvist E; Asvold BO; Edstorp J; Tuomi T; Bjarko VV; Carlsson S
- Review: ECLINICALMEDICINE. 2025;83:103222Zeng J; Beck M; Barouti AA; Loefvenborg JE; Carlsson S; Lampousi A-M
- Conference publication: EPILEPSIA. 2024;65:22Melin S; Tomson T; Sveinsson O; Carlsson S; Andersson T; Wirdefeldt K
- Conference publication: DIABETOLOGIA. 2024;67:S151-S152Lampousi A-M; Ahlqvist E; Alfredsson L; Askling J; Edstorp J; Di Giuseppe D; Grill V; Lofvenborg JE; Padyukov L; Sorgjerd EP; Tuomi T; Asvold BO; Carlsson S
- Conference publication: DIABETOLOGIA. 2024;67:S48Wei Y; Andersson T; Tuomi T; Nystrom T; Carlsson S
- Review: ADVANCES IN NUTRITION. 2024;15(5):100211Lampousi A-M; Lundberg T; Lofvenborg JE; Carlsson S
- Letter: DIABETOLOGIA. 2024;67(3):567-568Grill V; Sorgjerd E; Hals I; Carlsson S
- Conference publication: DIABETOLOGIA. 2023;66(SUPPL 1):S177-S178Edstorp J; Rossides M; Ahlqvist E; Alfredsson L; Rasouli B; Tuomi T; Carlsson S
- Conference publication: DIABETOLOGIA. 2023;66(SUPPL 1):S174-S175Lampousi A-M; Lundberg T; Lofvenborg JE; Carlsson S
- Conference publication: DIABETOLOGIA. 2023;66(SUPPL 1):S170Wei Y; Carlsson S
- Meeting abstract: LANCET GLOBAL HEALTH. 2023;11:S1Wei Y; Zhan Y; Carlsson S
- Conference publication: EPILEPSIA. 2022;63:151-152Melin S; Wirdefeldt K; Sveinsson O; Andersson T; Carlsson S; Tomson T
- Conference publication: DIABETOLOGIA. 2022;65(SUPPL 1):S114Wei Y; Ahlqvist E; Andersson T; Tuomi T; Carlsson S
- Conference publication: DIABETOLOGIA. 2022;65(SUPPL 1):S153Edstorp J; Ahlqvist E; Alfredsson L; Grill V; Rasouli B; Sorgjerd EP; Tuomi T; Asvold B; Carlsson S
- Conference publication: DIABETOLOGIA. 2022;65(SUPPL 1):S150-S151Lampousi A-M; Carlsson S; Lofvenborg JE
- Review: FRONTIERS IN ENDOCRINOLOGY. 2022;13:917850Carlsson S
- Review: DIABETIC MEDICINE. 2022;39(6):e14830Edstorp J; Lampousi A-M; Carlsson S
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Grants
- Early-onset type 2 diabetes, a growing threat to public health with a strong social gradientSwedish Research Council for Health Working Life and Welfare1 January 2026
- Time trends in the genetic and environmental contributions to type 1 diabetes in Sweden 1982–2020Barndiabetesfondens1 May 2025 - 30 April 2026
- Swedish Research Council1 January 2023 - 31 December 2026Diabetes is a chronic disease affecting 1/5 swedes during their lifetime, associated with CVD and reduced life expectancy. With a finer classification of diabetes, opportunities arise for better assessment of factors influencing onset and prognosis, which may lead to improved prevention. This project involves subtypes within the broad categories T1D and T2DLADA– a common form of autoimmune diabetes, newly proposed subtypes of T2D- including a severe insulin resistant and a severe insulin deficient type, and adult onset T1D. We aim to provide new knowledge on the interplay environmental vs. genetic factors influences in the aetiology of these largely unexplored subtypes of diabetes. To this aim, we are conducting the world´s largest study of LADA, the ESTRID-study, with incident cases of LADA and T2D subtypes and clinical, genetic and environmental information. The Norwegian HUNT-study, European Epic-InterAct and UK biobank, which includes adult onset T1D, will be used for extensions and replication. We will use Mendelian Randomization design for causal inference. ESTRID and HUNT are linked to national registers allowing us to follow patients from diagnosis and assess the prognostic role of clinical, genetic and lifestyle factors. The aim is to identify factors increasing the risk of autoimmune diabetes in adults and different forms of T2D and factors contributing to poor prognosis. Such knowledge is central future efforts to prevent diabetes and its consequences.
- Swedish Research Council for Health Working Life and Welfare1 January 2021 - 31 December 2024
- Infections, antibiotics, tobacco, genetic susceptibility and risk of Latent autoimmune diabetes in adults and type 2 diabetesNovo Nordisk Foundation1 January 2020 - 31 December 2022
- Swedish Research Council1 January 2019 - 31 December 2022
- Swedish Research Council for Health Working Life and Welfare1 January 2019 - 31 December 2022
- LADA-LATENT AUTOIMMUNE DIABETES IN ADULTS, RISK FACTORS AND PROGNOSISNovo Nordisk Foundation1 January 2018 - 31 December 2020
- Swedish Research Council for Health Working Life and Welfare1 October 2017 - 30 September 2021
- INFLUENCE OF DIET ON THE RISK OF LADA (LATENT AUTOIMMUNE DIABETES IN ADULTS) AND TYPE 2 DIABETESNovo Nordisk Foundation1 January 2017 - 1 January 2018
- Swedish Research Council for Health Working Life and Welfare1 December 2015 - 30 September 2016
- Swedish Research Council1 January 2015 - 31 December 2018
- Swedish Research Council for Health Working Life and Welfare1 December 2012 - 31 December 2015
- Swedish Research Council1 January 2010 - 31 December 2012
Employments
- Senior Lecturer, Institute of Environmental Medicine, Karolinska Institutet, 2015-
Degrees and Education
- Docent, Karolinska Institutet, 2008
- Doctor Of Philosophy, Institute of Environmental Medicine, Karolinska Institutet, 2003
- Licentiate Degree, Institute of Environmental Medicine, Karolinska Institutet, 1999