Signal Transduction

We focus on Signal transduction in the pancreatic beta-cell. Pancreatic beta-cell signal transduction is complex and involves a well-regulated interaction of a number of signals generated by the metabolism of glucose and the activation of a variety of receptor-operated pathways. Our future research will tell to what extent these various signalling pathways are really regulatory pathways under in vivo conditions, or rather serve as signalling pathways maintaining normal beta-cell function.