Gallery, articles and testimonies

Enjoy the LCI art gallery!

Xiaoyan Sun - Nerves and hair follicles in skin

Growing hair crosssection Growing hair bulb Dividing cell in tissue  
Eduarde Rohner - Hair follicle Hui Gao - Lipid droplets NADPH and TMRI imaging using 2 photon microscopy
Tomas McKenna Tomas McKenna Stephanie Wood-NK tumourcell
Mikaela Wiking-Differentiated cells Rudger Shutten Tripple division Pablo Hernandez Varas-Migrating H1299
Tomas McKenna Karl Annusver-Mouse skin Tomas McKenna
WT mouse hippocampal slice showing CA1 neurons intracellular injected with Lucifer yellow (green) and stained with DAPI (blue)  

                                                                        

Selected Publications

Publications 2018

Unique Phenotypic Characteristics of Recently Transmitted HIV-1 Subtype C Envelope Glycoprotein gp120: Use of CXCR6 Coreceptor by Transmitted Founder Viruses.
Ashokkumar M, Aralaguppe S, Tripathy S, Hanna L, Neogi U
J. Virol. 2018 05;92(9):
Neuronal Aβ42 is enriched in small vesicles at the presynaptic side of synapses.
Yu Y, Jans D, Winblad B, Tjernberg L, Schedin-Weiss S
Life Sci Alliance 2018 Jun;1(3):e201800028
Brief Exposure of Skin to Near-Infrared Laser Modulates Mast Cell Function and Augments the Immune Response.
Kimizuka Y, Katagiri W, Locascio J, Shigeta A, Sasaki Y, Shibata M, et al
J. Immunol. 2018 Dec;201(12):3587-3603
27-Hydroxycholesterol Induces Aberrant Morphology and Synaptic Dysfunction in Hippocampal Neurons.
Merino-Serrais P, Loera-Valencia R, Rodriguez-Rodriguez P, Parrado-Fernandez C, Ismail M, Maioli S, et al
Cereb. Cortex 2018 Nov;():
Reticular adhesions are a distinct class of cell-matrix adhesions that mediate attachment during mitosis.
Lock J, Jones M, Askari J, Gong X, Oddone A, Olofsson H, et al
Nat. Cell Biol. 2018 Nov;20(11):1290-1302
Characterization of Inducible Transcription and Translation-Competent HIV-1 Using the RNAscope ISH Technology at a Single-Cell Resolution.
Zhang W, Svensson Akusjärvi S, Sönnerborg A, Neogi U
Front Microbiol 2018 ;9():2358
Single-Cell Transcriptomics of Traced Epidermal and Hair Follicle Stem Cells Reveals Rapid Adaptations during Wound Healing.
Joost S, Jacob T, Sun X, Annusver K, La Manno G, Sur I, et al
Cell Rep 2018 Oct;25(3):585-597.e7
KIF13A-regulated RhoB plasma membrane localization governs membrane blebbing and blebby amoeboid cell migration.
Gong X, Didan Y, Lock J, Strömblad S
EMBO J. 2018 Sep;37(17):
Distinct roles of mesenchymal stem and progenitor cells during the development of acute myeloid leukemia in mice.
Xiao P, Sandhow L, Heshmati Y, Kondo M, Bouderlique T, Dolinska M, et al
Blood Adv 2018 Jun;2(12):1480-1494
Active and inactive β1 integrins segregate into distinct nanoclusters in focal adhesions.
Spiess M, Hernandez-Varas P, Oddone A, Olofsson H, Blom H, Waithe D, et al
J. Cell Biol. 2018 Jun;217(6):1929-1940
Somatic mutagenesis in satellite cells associates with human skeletal muscle aging.
Franco I, Johansson A, Olsson K, Vrtačnik P, Lundin P, Helgadottir H, et al
Nat Commun 2018 02;9(1):800
TOM70 Sustains Cell Bioenergetics by Promoting IP3R3-Mediated ER to Mitochondria Ca Transfer.
Filadi R, Leal N, Schreiner B, Rossi A, Dentoni G, Pinho C, et al
Curr. Biol. 2018 Feb;28(3):369-382.e6

Publications 2017

Publications 2016

Publications 2015

Publications 2014

Publications 2013

Publications 2012

Publications 2011

 

Testimonies

Training and usage of the facility

"The training was very good. It was the first time in my career I had such a personalized and complete training on microscopy. It is very useful to spend several hours with someone from the LCI staff during the training and learn how to image our samples in the best way possible"
"The theory component of the training is invaluable!"
"I never had such a thorough introduction to microscopy anywhere else and I found what one learned very valuable for my experiments"
"It's great that those extensive trainings exist! It really helps to get most out of your samples"
"Best imaging place ever!"
"The staff of the facility are available to help troubleshoot at short notice and they are constantly bringing new technologies and techniques to the facility to improve results."

" I really like that the microscopes are maintained well and LCI is very helpful with any questions, trouble-shooting or even bouncing ideas"

" LCI staff are all very helpful and willing to help and interested!"

"The LCI imaging facility is the best imaging facility I encountered during my career regarding equipment (keeping up with new developments), training and support"

Microscopy courses

Vintage 2017:
"I think it's a great course that covers the basic knowledge all people working with any type of microscopy should know about!"
"The whole course is excellent already. Highly recommended!"
"The engagement of the teachers was amazing! The lectures, the workshops, and the student challenges were all very relevant and I enjoyed attending them."
"Very helpful to understand the limitation of the microscope and how the relation between the objective parameters and the subjective imperission of an image"
"I love best: Lecture contents, invited lectures and workshops. Practical information and something I can apply to my research."
"I think the course has covered a lot of the knowledge concerning imaging with microscopy. Beside the content described in the intended learning outcomes, there were also some very good lectures given by invited lecturers to cover extended and relevant knowledge."
"A very good course that cover both the basics and advanced topics about microscopy. Workshops were a very good idea"
"The course was done wholeheartedly by teachers experienced in microscopy, the mood was always good and the students felt free to ask questions and take part in the teaching."
"Student image challenge helped to understand how we should approach to our scientific question. Sylvie and Gabis lectures about sample preparation, microscope setup etc, were very valuable to understand the big picture. I also liked the repetitions of the information to make sure that we remember the most important things. Weekly quizzes also helped to put our knowledge into the context. Homework was also very good, because that forced us to really look at our machine and understand its capabilities. And of course the cinnamon buns were excellent :)"

 

Vintage 2016:
"Most of the lectures and all the workshops had excellent content, perfectly organized and structured, with a lot of effort from the teachers to ensure that each student follows and understands the subject, and to put the most practically important aspects into focus. And the opportunity to bring and work with "my very own" sample was invaluable for me."
"I really liked how things evolved from very basic to a more complex level. Sylvie was making sure in each step that we understood everything. The quiz sessions were very helpful to digest the knowledge.The student sample workshop, sample preparation workshop were very helpful."
"I found extremely useful the student challenge workshop as I could practically identify the drawbacks of my sample design and decide for strategies to improve it. I appreciate a lot how devoted the course teachers were, many times spending much more time with all the students out of the scheduled time, in order to ensure that all of us understood and learnt a lot. I also liked the quizz part which helped me understand to a great extent the content of the lectures."
"It was very good that we had the opportunity to get advice regarding our own sample, in that way we would definitely learn things that will improve our future experiments.'
'Workshop and student challenge offered a valuable chance to put in perspective the lectures."
"I think that every lecture/workshop gave new insights in my research."

 

Vintage 2015:
"The LCI staff was motivating us and was very patient with us, always super energetic and ready to help despite the super intense program!"
'The focus on fundamental knowledge and practical workshops are very good."
"In general the course was excellent.'
"The course is one of the best I have had in my 4 years at KI."

Microscopy