Welcome to the ESTRID study!
We are a research group at Karolinska Institutet, Stockholm, Sweden. Our goal is to find risk factors for the development of LADA (latent autoimmune diabetes in adults) and type 2 diabetes. We study genetic and lifestyle factors as well as how these interact. The overall aim is to increase the possibilities to prevent diabetes. ESTRID is short for Epidemiological study of risk factors for LADA and type 2 diabetes.
Low birth weight and adult overweight increase the risk of LADA and type 2-diabetes in adults
Low birth weight and adult overweight increase the risk of developing LADA and type 2-diabetes in adults, a new study from Karolinska Institutet has found. The study was conducted using Mendelian Randomization to study the connection between birth weight, adult overweight and the risk of LADA.
Increased risk of LADA in people who smoke or use smokeless tobacco
People who smoke or use smokeless tobacco have an increased risk of developing Latent Autoimmune Diabetes in Adults (LADA) a new study from Karolinska Institute shows. The study investigated how tobacco use and genetic susceptibility affect the risk of developing LADA.
Long-term breastfeeding may reduce the risk of type 1 diabetes in children
Long-term breastfeeding and later introduction to gluten, cow's milk and fruit may reduce the risk of developing type 1 diabetes in children, a new literature review shows. Overall, the existing research suggests that diet in the first year of life may have an impact on children's risk of developing type 1 diabetes.
A healthy lifestyle reduces the risk of LADA and Type 2 diabetes
Findings from a recently published study in Diabetes Research and Clinical Practice show that a healthy lifestyle is associated with a 49% reduction in the risk to develop Latent autoimmune diabetes in adults (LADA). This study was based on data from the ESTRID study and found that the association between a healthy lifestyle and reduced diabetes risk was also seen in individuals with a family history of diabetes and a high genetic risk of developing diabetes.
High dietary fish intake reduces the risk of diabetes among individuals with GAD antibodies
Individuals with GAD antibodies are at increased risk of developing LADA. A new study shows that the risk of diabetes is particularly high among those who also have low fish intake.
High physical activity reduces the risk of LADA and type 2 diabetes
Exercising for 30 minutes three times per week is associated with a 40% reduced risk of Latent Autoimmune Diabetes in Adults (LADA), but only in individuals who do not have a high genetic risk of developing diabetes. High physical activity is also associated with a 50% reduced risk of type 2 diabetes, regardless of genetic susceptibility.
Consumption of processed red meat increases the risk of LADA
Consumption of processed red meat, such as sausage and bacon, is linked to an increased risk of developing LADA. The risk is particularly high in people with high-risk genes for autoimmune diabetes.
Increased body weight does not fully explain the association between sweetened beverages and diabetes
In a new study, Phd student Josefin Löfvenborg further investigates how sweeteend beverage consumption affects the risk of diabetes.
New report about environmental and lifestyle factors related to diabetes
A new report summarizes existing research on the relationship between lifestyle, environmental factors and the development of diabetes. Emphasis is placed on type 2 diabetes, which is the most common form of diabetes, but also type 1 diabetes and LADA are discussed. Sofia Carlsson, responsible researcher for the ESTRID study, has led the work with the report.
ESTRID has received VR and FORTE funding
The two grants totals more than 10 000 000 SEK and should be used for the study of risk factors and prognosis for LADA (latent autoimmune diabetes in adults).
Overweight and genotype interact in the development of LADA
Overweight individuals carrying highrisk genes are at a significantly higher risk of developing LADA shows a new study.