Klinisk fysiologi – Marcus Carlssons forskargrupp

Vår forskning fokuserar på att förstå kardiovaskulär patofysiologi genom en kombination av kardiovaskulär avbildning och fysiologiska experiment, med särskilt fokus på magnetresonansavbildning (MRI) av hjärt‑kärlsystemet. Vi består av en mycket tvärvetenskaplig grupp av läkare, fysiker och ingenjörer. Vi leder samt deltar i ett brett spektrum av fysiologiska studier, från grundläggande metodutveckling och translationella avbildningsstudier, hela vägen till aktiva kliniska prövningar.

En del av:
Tre personer vid en MR utrustning
Research group leader
Porträtt av man i mörkblå kavaj. Foto: Erik Flyg

Research group leader

Professor Marcus Carlsson is research group leader of the Clinical Physiology group at the Department of Molecular Medicine and Surgery.

Calendar Clinical Physiology

News Clinical Physiology

Our research

Our research is centred on the study of cardiac and cardiovascular physiology, focussing in particular on physiological measurement methods to better understanding, diagnose, and predict cardiovascular and cardiopulmonary disorders. The advanced imaging and methodological research performed within the group, together with the direct integration and close proximity to the clinical unit of Clinical Physiology, creates a unique foundation for impacting translational science and rapid integration of novel techniques into ongoing clinical trials and assessments.  

The group is headed by Professor Marcus Carlsson and belongs to the Department of Molecular Medicine and Surgery, and is also the main research team at the clinical unit of Clinical Physiology at the Karolinska University Hospital in Solna. We have ongoing collaboration with other research groups at several other institutions at KI Nord, KI Syd and KI Solna, and have current involvement in a number of clinical trials on the role of cardiovascular MRI.

Research teams and project leaders 

The work in our group is made possible by the multidisciplinary collaboration between medical doctors, medical physicists, and engineers, working in synergy to enhance our understanding of the cardiovascular system. Spread across a number of research teams and project leaders, individual efforts enhance group impact.  

Clinical physiology
Porträtt av man i mörkblå kavaj. Foto: Erik Flyg
Group leader: Marcus Carlsson

Clinical physiology

Our research focuses on understanding cardiovascular pathophysiology through a combination of cardiovascular imaging and physiological experimentation, with a particular focus on cardiovascular magnetic resonance imaging (MRI). Consisting of a highly multidisciplinary group of medical doctors, physicists, and engineers, we lead and participate in a wide range of physiological studies, ranging from fundamental method developments and translational imaging studies, all the way to active clinical trials. 

Translational cardiovascular imaging
Porträtt av man i blå jeansjacka. Foto: Ulf Sirborn
Team leader: David Marlevi

Translational cardiovascular imaging

The translational cardiovascular imaging team combines advanced medical imaging with bioengineering-driven image analysis to address urgent clinical challenges in cardiovascular care, as well as use novel imaging techniques to advance our understanding of cardiovascular disease.

Quantitative cardiovascular physiology
Jannike Nickander Foto: Fredrik Nickander
Team leader: Jannike Nickander

Quantitative cardiovascular physiology

The quantitative cardiovascular physiology team employs experimental methods for increased physiological insights, with a particular focus on non-invasive mapping of microvascular dysfunction. Utilizing a variety of techniques, cardiac MRI is a focus area, with perfusion mapping providing novel inisghts into microvascular behaviour.  

Project leaders

PI: Andreas Sigfridsson

  • Advanced CMR acquisition strategies

PI: Felicia Seemann

  • Cardiopulmonary imaging

PI: Alexander Fyrdahl

  • Computational and quantitative MRI

PI: Björn Wieslander

  • Cardiorespiratory hemodynamics

Publikationer

Alla gruppmedlemmars publikationer

Medarbetare och kontakt

Gruppledare

Alla medarbetare i gruppen

Contact and visit us

Postal address

K1 Molekylär medicin och kirurgi 
K1 MMK Klinisk fysiologi
SE-171 76 Stockholm

Visiting address

Eugeniavägen 3, Karolinska University Hospital, A8:01, 17176 Stockholm