MWLC Publications
The publications from Ming Wai Lau Centre for Reparative Medicine reflect collaborative efforts both within and outside of KI. The selected publications are sorted by researchers.
Bioinformatics Platform
Cheng, S., Brenière-Letuffe, D., Ahola, V., Wong, A. O. T., Keung, H. Y., Gurung, B., Zheng, Z., Costa, K. D., Lieu, D. K., Keung, W., & Li, R. A. (2023). Single-cell RNA sequencing reveals maturation trajectory in human pluripotent stem cell-derived cardiomyocytes in engineered tissues. IScience, 26(4), 106302.
https://doi.org/10.1016/j.isci.2023.106302
Gonçalo Castelo-Branco
Deng, Y., Bartosovic, M., Kukanja, P., Zhang, D., Liu, Y., Su, G., Enninful, A., Bai, Z., Castelo-Branco, G., & Fan, R. (2022). Spatial-CUT&Tag: Spatially resolved chromatin modification profiling at the cellular level. Science, 375(6581), 681–686.
https://doi.org/10.1126/science.abg7216
Meijer, M., Agirre, E., Kabbe, M., van Tuijn, C. A., Heskol, A., Zheng, C., Mendanha Falcão, A., Bartosovic, M., Kirby, L., Calini, D., Johnson, M. R., Corces, M. R., Montine, T. J., Chen, X., Chang, H. Y., Malhotra, D., & Castelo-Branco, G. (2022). Epigenomic priming of immune genes implicates oligodendroglia in multiple sclerosis susceptibility. Neuron.
https://doi.org/10.1016/j.neuron.2021.12.034
Bonetti, A., Agostini, F., Suzuki, A. M., Hashimoto, K., Pascarella, G., Gimenez, J., Roos, L., Nash, A. J., Ghilotti, M., Cameron, C. J. F., Valentine, M., Medvedeva, Y. A., Noguchi, S., Agirre, E., Kashi, K., Samudyata, Luginbühl, J., Cazzoli, R., Agrawal, S., … Carninci, P. (2020). RADICL-seq identifies general and cell type–specific principles of genome-wide RNA-chromatin interactions. Nature Communications, 11(1), 1018.
https://doi.org/10.1038/s41467-020-14337-6
Marisca, R., Hoche, T., Agirre, E., Hoodless, L. J., Barkey, W., Auer, F., Castelo-Branco, G., & Czopka, T. (2020). Functionally distinct subgroups of oligodendrocyte precursor cells integrate neural activity and execute myelin formation. Nature Neuroscience, 23(3), 363–374.
https://doi.org/10.1038/s41593-019-0581-2
Samudyata, Castelo-Branco, G., & Liu, J. (2020). Epigenetic regulation of oligodendrocyte differentiation: From development to demyelinating disorders. GLIA, 68(8), 1619–1630.
https://doi.org/10.1002/glia.23820
Falcão, A. M., Meijer, M., Scaglione, A., Rinwa, P., Agirre, E., Liang, J., Larsen, S. C., Heskol, A., Frawley, R., Klingener, M., Varas-Godoy, M., Raposo, A. A. S. F., Ernfors, P., Castro, D. S., Nielsen, M. L., Casaccia, P., & Castelo-Branco, G. (2019). PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination. Cell Reports, 27(4), 1090-1102.e10.
https://doi.org/10.1016/j.celrep.2019.03.108
Floriddia, E. M., & Castelo-Branco, G. (2019). Ancestry Tracing: Uncovering a Gliomagenesis Master Regulator. Cell Stem Cell, 24(5), 677–679.
https://doi.org/10.1016/j.stem.2019.04.006
Jäkel, S., Agirre, E., Mendanha Falcão, A., van Bruggen, D., Lee, K. W., Knuesel, I., Malhotra, D., Ffrench-Constant, C., Williams, A., & Castelo-Branco, G. (2019). Altered human oligodendrocyte heterogeneity in multiple sclerosis. Nature, 566(7745), 543–547.
https://doi.org/10.1038/s41586-019-0903-2
Kupari, J., Häring, M., Agirre, E., Castelo-Branco, G., & Ernfors, P. (2019). An Atlas of Vagal Sensory Neurons and Their Molecular Specialization. Cell Reports, 27(8), 2508-2523.e4.
https://doi.org/10.1016/j.celrep.2019.04.096
Marques, S., van Bruggen, D., & Castelo-Branco, G. (2019). Single-Cell RNA Sequencing of Oligodendrocyte Lineage Cells from the Mouse Central Nervous System. Methods in Molecular Biology (Clifton, N.J.), 1936, 1–21.
https://doi.org/10.1007/978-1-4939-9072-6_1
Samudyata, Amaral, P. P., Engström, P. G., Robson, S. C., Nielsen, M. L., Kouzarides, T., & Castelo-Branco, G. (2019). Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells. Experimental Cell Research, 381(1), 129–138.
https://doi.org/10.1016/j.yexcr.2019.05.006
Falcão, A. M., van Bruggen, D., Marques, S., Meijer, M., Jäkel, S., Agirre, E., Samudyata, Floriddia, E. M., Vanichkina, D. P., Ffrench-Constant, C., Williams, A., Guerreiro-Cacais, A. O., & Castelo-Branco, G. (2018). Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis. Nature Medicine, 24(12), 1837–1844.
https://doi.org/10.1038/s41591-018-0236-y
La Manno, G., Soldatov, R., Zeisel, A., Braun, E., Hochgerner, H., Petukhov, V., Lidschreiber, K., Kastriti, M. E., Lönnerberg, P., Furlan, A., Fan, J., Borm, L. E., Liu, Z., van Bruggen, D., Guo, J., He, X., Barker, R., Sundström, E., Castelo-Branco, G., … Kharchenko, P. V. (2018). RNA velocity of single cells. Nature, 560(7719), 494–498.
https://doi.org/10.1038/s41586-018-0414-6
Marques, S., van Bruggen, D., Vanichkina, D. P., Floriddia, E. M., Munguba, H., Väremo, L., Giacomello, S., Falcão, A. M., Meijer, M., Björklund, Å. K., Hjerling-Leffler, J., Taft, R. J., & Castelo-Branco, G. (2018). Transcriptional Convergence of Oligodendrocyte Lineage Progenitors during Development. Developmental Cell, 46(4), 504-517.e7.
https://doi.org/10.1016/j.devcel.2018.07.005
Samudyata, Castelo-Branco, G., & Bonetti, A. (2018). Birth, coming of age and death: The intriguing life of long noncoding RNAs. Seminars in Cell & Developmental Biology, 79, 143–152.
https://doi.org/10.1016/j.semcdb.2017.11.012
Sijie Chen
Ho, P.-Y., Chou, T. Y., Kam, C., Huang, W., He, Z., Ngan, A. H. W., & Chen, S. (2023). A dual organelle-targeting mechanosensitive probe. Science Advances, 9(2), eabn5390.
https://doi.org/10.1126/sciadv.abn5390
Wu, M.-Y., Wong, A. Y. H., Leung, J.-K., Kam, C., Wu, K. L.-K., Chan, Y.-S., Liu, K., Ip, N. Y., & Chen, S. (2021). A near-infrared AIE fluorescent probe for myelin imaging: From sciatic nerve to the optically cleared brain tissue in 3D. Proceedings of the National Academy of Sciences, 118 (45) e2106143118.
https://doi.org/10.1073/pnas.2106143118
Ho, P.-Y., Lee, S.-Y., Kam, C., Zhu, J., Shan, G.-G., Hong, Y., Wong, W.-Y., & Chen, S. (2021). Fluorescence Imaging and Photodynamic Inactivation of Bacteria Based on Cationic Cyclometalated Iridium(III) Complexes with Aggregation‐Induced Emission Properties (Adv. Healthcare Mater. 24/2021). Advanced Healthcare Materials, 10(24), 2170116.
https://doi.org/10.1002/adhm.202170116
Song, F., Zhang, C., Dong, H., Fan, Y., Wu, M.-Y., Shan, G., Lai, P., Gao, H., Zhao, Y. S., & Chen, S. (2021). A switchable multimode microlaser based on an AIE microsphere. J. Mater. Chem. C.
https://doi.org/10.1039/D1TC00604E
Wu, M.-Y., Gu, M., Leung, J.-K., Li, X., Yuan, Y., Shen, C., Wang, L., Zhao, E., & Chen, S. (2021). A Membrane-Targeting Photosensitizer with Aggregation-Induced Emission Characteristics for Highly Efficient Photodynamic Combat of Human Coronaviruses. Small, 17(30), 2101770.
https://doi.org/10.1002/smll.202101770
Huang, L., Xu, S., Wang, Z., Xue, K., Su, J., Song, Y., Chen, S., Zhu, C., Tang, B. Z., & Ye, R. (2020). Self-Reporting and Photothermally Enhanced Rapid Bacterial Killing on a Laser-Induced Graphene Mask. ACS Nano, 14(9), 12045–12053.
https://doi.org/10.1021/acsnano.0c05330
OwYong, T. C., Ding, S., Wu, N., Fellowes, T., Chen, S., White, J. M., Wong, W. W. H., & Hong, Y. (2020). Optimising molecular rotors to AIE fluorophores for mitochondria uptake and retention. Chemical Communications, 56(94), 14853–14856. https://doi.org/10.1039/D0CC06411D
Liu, C., Wang, X., Liu, J., Yue, Q., Chen, S., Lam, J. W. Y., Luo, L., & Tang, B. Z. (2020). Near-Infrared AIE Dots with Chemiluminescence for Deep-Tissue Imaging. Advanced Materials, 32(43), 2004685.
https://doi.org/https://doi.org/10.1002/adma.202004685
Xu, W., Zhang, Z., Kang, M., Guo, H., Li, Y., Wen, H., Lee, M. M. S., Wang, Z., Kwok, R. T. K., Lam, J. W. Y., Li, K., Xi, L., Chen, S., Wang, D., & Tang, B. Z. (2020). Making the Best Use of Excited-State Energy: Multimodality Theranostic Systems Based on Second Near-Infrared (NIR-II) Aggregation-Induced Emission Luminogens (AIEgens). ACS Materials Letters, 2(8), 1033–1040.
https://doi.org/10.1021/acsmaterialslett.0c00263
Lv, W., Long, K., Yang, Y., Chen, S., Zhan, C., & Wang, W. (2020). A Red Light-Triggered Drug Release System Based on One-Photon Upconversion-Like Photolysis. Advanced Healthcare Materials, 9(21), 2001118.
https://doi.org/https://doi.org/10.1002/adhm.202001118
Gao, H., Zhao, X., & Chen, S. (2018). AIEgen-Based Fluorescent Nanomaterials: Fabrication and Biological Applications. Molecules, 23(2), 419.
https://doi.org/10.3390/molecules23020419
Hoffecker, I. T., Chen, S., Gådin, A., Bosco, A., Teixeira, A. I., & Högberg, B. (2019). Solution-Controlled Conformational Switching of an Anchored Wireframe DNA Nanostructure. Small, 15(1), 1803628.
https://doi.org/10.1002/smll.201803628
Tu, Y., Yu, Y., Zhou, Z., Xie, S., Yao, B., Guan, S., Situ, B., Liu, Y., Kwok, R. T. K., Lam, J. W. Y., Chen, S., Huang, X., Zeng, Z., & Tang, B. Z. (2019). Specific and Quantitative Detection of Albumin in Biological Fluids by Tetrazolate-Functionalized Water-Soluble AIEgens. ACS Applied Materials & Interfaces, 11(33), 29619–29629.
https://doi.org/10.1021/acsami.9b10359
Li, F., Han, J., Cao, T., Lam, W., Fan, B., Tang, W., Chen, S., Fok, K. L., & Li, L. (2019). Design of self-assembly dipeptide hydrogels and machine learning via their chemical features. Proceedings of the National Academy of Sciences, 116(23), 11259–11264.
https://doi.org/10.1073/pnas.1903376116
Xie, S., Wong, A. Y. H., Chen, S., & Tang, B. Z. (2019). Fluorogenic Detection and Characterization of Proteins by Aggregation-Induced Emission Methods. Chemistry (Weinheim an Der Bergstrasse, Germany), 25(23), 5824–5847.
https://doi.org/10.1002/chem.201805297
Wong, A. Y. H., Xie, S., Tang, B. Z., & Chen, S. (2019). Fluorescent Silver Staining of Proteins in Polyacrylamide Gels. Journal of Visualized Experiments, 146.
https://doi.org/10.3791/58669
Chen, S., Liu, J., Zhang, S., Zhao, E., Yu, C. Y. Y., Hushiarian, R., Hong, Y., & Tang, B. Z. (2018). Biochromic silole derivatives: a single dye for differentiation, quantitation and imaging of live/
Liu, L., Zou, Q., Leung, J.-K., Wang, J.-L., Kam, C., Chen, S., Feng, S., & Wu, M.-Y. (2019). Ultrafast labeling and high-fidelity imaging of mitochondria in cancer cells using an aggregation-enhanced emission fluorescent probe. Chemical Communications, 55(97), 14681–14684.
https://doi.org/10.1039/C9CC07775H
Zhao, E., Lai, P., Xu, Y., Zhang, G., & Chen, S. (2020). Fluorescent Materials With Aggregation-Induced Emission Characteristics for Array-Based Sensing Assay. Frontiers in Chemistry, 8, 288.
https://doi.org/10.3389/fchem.2020.00288
Gu, M., Zeng, Z., Wu, M., Leung, J., Zhao, E., Wang, S., & Chen, S. (2019). Imaging Macrophage Phagocytosis Using AIE Luminogen‐Labeled E. coli. Chemistry – An Asian Journal, 14(6), 775–780.
https://doi.org/10.1002/asia.201801859
Wu, M., Leung, J., Liu, L., Kam, C., Chan, K. Y. K., Li, R. A., Feng, S., & Chen, S. (2020). A Small‐Molecule AIE Chromosome Periphery Probe for Cytogenetic Studies. Angewandte Chemie International Edition, 59(26), 10327–10331.
https://doi.org/10.1002/anie.201916718
Gao, H., Kam, C., Chou, T. Y., Wu, M.-Y., Zhao, X., & Chen, S. (2020). A simple yet effective AIE-based fluorescent nano-thermometer for temperature mapping in living cells using fluorescence lifetime imaging microscopy. Nanoscale Horizons, 5(3), 488–494.
https://doi.org/10.1039/C9NH00693A
Xie, S., Wong, A. Y. H., Kwok, R. T. K., Li, Y., Su, H., Lam, J. W. Y., Chen, S., & Tang, B. Z. (2018). Fluorogenic Ag + -Tetrazolate Aggregation Enables Efficient Fluorescent Biological Silver Staining. Angewandte Chemie International Edition, 57(20), 5750–5753.
https://doi.org/10.1002/anie.201801653
Simon Elsässer
Lafranchi, L., Schlesinger, D., Kimler, K. J., & Elsässer, S. J. (2020). Universal Single-Residue Terminal Labels for Fluorescent Live Cell Imaging of Microproteins. Journal of the American Chemical Society, jacs.0c09574.
https://doi.org/10.1021/jacs.0c09574
Meineke, B., Heimgärtner, J., Eirich, J., Landreh, M., & Elsässer, S. J. (2020). Site-Specific Incorporation of Two ncAAs for Two-Color Bioorthogonal Labeling and Crosslinking of Proteins on Live Mammalian Cells. Cell Reports, 31(12), 107811.
https://doi.org/10.1016/j.celrep.2020.107811
Navarro, C., Lyu, J., Katsori, A.-M., Caridha, R., & Elsässer, S. J. (2020). An embryonic stem cell-specific heterochromatin state promotes core histone exchange in the absence of DNA accessibility. Nature Communications, 11(1), 5095.
https://doi.org/10.1038/s41467-020-18863-1
Pesic, M., Egamberdieva, D., Kolodziejczyk, B., Elsässer, S. J., Neergheen, V. S., & Kagansky, A. (2020). Towards policies that capture the expected value of biomolecular diversity for drug discovery, human health, and well-being. Biologia Futura.
https://doi.org/10.1007/s42977-020-00043-3
Kumar, B., & Elsässer, S. (2019). Quantitative multiplexed ChIP reveals global alterations that shape promoter bivalency in ground state embryonic stem cells. Cell Reports.
https://doi.org/10.1101/557082
van Husen, L. S., Schedin-Weiss, S., Trung, M. N., Kazmi, M. A., Winblad, B., Sakmar, T. P., Elsässer, S. J., & Tjernberg, L. O. (2019). Dual Bioorthogonal Labeling of the Amyloid-β Protein Precursor Facilitates Simultaneous Visualization of the Protein and Its Cleavage Products. Journal of Alzheimer’s Disease, 72(2), 537–548.
https://doi.org/10.3233/JAD-190898
Elsässer, S. J. (2018). Generation of Stable Amber Suppression Cell Lines. In Methods in Molecular Biology (pp. 237–245).
https://doi.org/10.1007/978-1-4939-7574-7_15
Meineke, B., Heimgärtner, J., Lafranchi, L., & Elsässer, S. J. (2018). Methanomethylophilus alvus Mx1201 Provides Basis for Mutual Orthogonal Pyrrolysyl tRNA/Aminoacyl-tRNA Synthetase Pairs in Mammalian Cells. ACS Chemical Biology, 13(11), 3087–3096.
https://doi.org/10.1021/acschembio.8b00571
Neergheen-Bhujun, V., Awan, A. T., Baran, Y., Bunnefeld, N., Chan, K., dela Cruz, T. E., Egamberdieva, D., Elsässer, S., Johnson, M. V., Komai, S., Konevega, A. L., Malone, J. H., Mason, P., Nguon, R., Piper, R., Shrestha, U. B., Pešić, M., & Kagansky, A. (2017). Biodiversity, drug discovery, and the future of global health: Introducing the biodiversity to biomedicine consortium, a call to action. Journal of Global Health, 7(2).
https://doi.org/10.7189/jogh.07.020304
Christian Göritz
Dias, D. O., Kalkitsas, J., Kelahmetoglu, Y., Estrada, C. P., Tatarishvili, J., Holl, D., Jansson, L., Banitalebi, S., Amiry-Moghaddam, M., Ernst, A., Huttner, H. B., Kokaia, Z., Lindvall, O., Brundin, L., Frisén, J., & Göritz, C. (2021). Pericyte-derived fibrotic scarring is conserved across diverse central nervous system lesions. Nature Communications, 12(1), 5501.
https://doi.org/10.1038/s41467-021-25585-5
Dorst, M. C., Díaz-Moreno, M., Dias, D. O., Guimarães, E. L., Holl, D., Kalkitsas, J., Silberberg, G., & Göritz, C. (2021). Astrocyte-derived neurons provide excitatory input to the adult striatal circuitry. Proceedings of the National Academy of Sciences, 118(33), e2104119118.
https://doi.org/10.1073/pnas.2104119118
Dias, D. O., & Göritz, C. (2018). Fibrotic scarring following lesions to the central nervous system. Matrix Biology, 68–69, 561–570.
https://doi.org/10.1016/j.matbio.2018.02.009
Dias, D. O., Kim, H., Holl, D., Werne Solnestam, B., Lundeberg, J., Carlén, M., Göritz, C., & Frisén, J. (2018). Reducing Pericyte-Derived Scarring Promotes Recovery after Spinal Cord Injury. Cell, 173(1), 153-165.e22.
https://doi.org/10.1016/j.cell.2018.02.004
Reichenbach, B., Classon, J., Aida, T., Tanaka, K., Genander, M., & Göritz, C. (2018). Glutamate transporter Slc1a3 mediates inter‐niche stem cell activation during skin growth. The EMBO Journal, 37(9).
https://doi.org/10.15252/embj.201798280
Francois Lallemend
Faure, L., Wang, Y., Kastriti, M. E., Fontanet, P., Cheung, K. K. Y., Petitpré, C., Wu, H., Sun, L. L., Runge, K., Croci, L., Landy, M. A., Lai, H. C., Consalez, G. G., de Chevigny, A., Lallemend, F., Adameyko, I., & Hadjab, S. (2020). Single cell RNA sequencing identifies early diversity of sensory neurons forming via bi-potential intermediates. Nature Communications, 11(1), 4175.
https://doi.org/10.1038/s41467-020-17929-4
Romanov, R. A., Tretiakov, E. O., Kastriti, M. E., Zupancic, M., Häring, M., Korchynska, S., Popadin, K., Benevento, M., Rebernik, P., Lallemend, F., Nishimori, K., Clotman, F., Andrews, W. D., Parnavelas, J. G., Farlik, M., Bock, C., Adameyko, I., Hökfelt, T., Keimpema, E., & Harkany, T. (2020). Molecular design of hypothalamus development. Nature, 582(7811), 246–252.
https://doi.org/10.1038/s41586-020-2266-0
Bartesaghi, L., Wang, Y., Fontanet, P., Wanderoy, S., Berger, F., Wu, H., Akkuratova, N., Bouçanova, F., Médard, J. J., Petitpré, C., Landy, M. A., Zhang, M. D., Harrer, P., Stendel, C., Stucka, R., Dusl, M., Kastriti, M. E., Croci, L., Lai, H. C., … Chrast, R. (2019). PRDM12 Is Required for Initiation of the Nociceptive Neuron Lineage during Neurogenesis. Cell Reports, 26(13), 3484-3492.e4.
https://doi.org/10.1016/j.celrep.2019.02.098
Wang, Y., Wu, H., Fontanet, P., Codeluppi, S., Akkuratova, N., Petitpré, C., Xue-Franzén, Y., Niederreither, K., Sharma, A., Da Silva, F., Comai, G., Agirman, G., Palumberi, D., Linnarsson, S., Adameyko, I., Moqrich, A., Schedl, A., La Manno, G., Hadjab, S., & Lallemend, F. (2019). A cell fitness selection model for neuronal survival during development. Nature Communications, 10(1), 4137.
https://doi.org/10.1038/s41467-019-12119-3
Wang, Y., Wu, H., Zelenin, P., Fontanet, P., Wanderoy, S., Petitpré, C., Comai, G., Bellardita, C., Xue-Franzén, Y., Huettl, R. E., Huber, A. B., Tajbakhsh, S., Kiehn, O., Ernfors, P., Deliagina, T. G., Lallemend, F., & Hadjab, S. (2019). Muscle-selective RUNX3 dependence of sensorimotor circuit development. Development (Cambridge), 146(20).
https://doi.org/10.1242/dev.181750
Petitpré, C., Wu, H., Sharma, A., Tokarska, A., Fontanet, P., Wang, Y., Helmbacher, F., Yackle, K., Silberberg, G., Hadjab, S., & Lallemend, F. (2018). Neuronal heterogeneity and stereotyped connectivity in the auditory afferent system. Nature Communications, 9(1), 3691.
https://doi.org/10.1038/s41467-018-06033-3
Furlan, A., Dyachuk, V., Kastriti, M. E., Calvo-Enrique, L., Abdo, H., Hadjab, S., Chontorotzea, T., Akkuratova, N., Usoskin, D., Kamenev, D., Petersen, J., Sunadome, K., Memic, F., Marklund, U., Fried, K., Topilko, P., Lallemend, F., Kharchenko, P. V., Ernfors, P., & Adameyko, I. (2017). Multipotent peripheral glial cells generate neuroendocrine cells of the adrenal medulla. Science, 357, 6346.
https://doi.org/10.1126/science.aal3753
Peng, C., Li, L., Zhang, M. D., Gonzales, C. B., Parisien, M., Belfer, I., Usoskin, D., Abdo, H., Furlan, A., Häring, M., Lallemend, F., Harkany, T., Diatchenko, L., Hökfelt, T., Hjerling-Leffler, J., & Ernfors, P. (2017). MIR-183 cluster scales mechanical pain sensitivity by regulating basal and neuropathic pain genes. Science, 356(6343), 1168–1171.
https://doi.org/10.1126/science.aam7671
Ning Xu Landén
Li D, Peng H, Qu L, Sommar P, Wang A, Chu T, Li X, Bi X, Liu Q, Sérézal IG, Rollman O, Lohcharoenkal W, Zheng X, Angelstig SE, Grünler J, Pivarcsi A, Sonkoly E, Catrina S-B, Xiao C, Ståhle M, Mi Q-S, Zhou L&Landén, N. X. (2020). miR-19a/b and miR-20a promote wound healing by regulating the inflammatory response of keratinocytes. Journal of Investigative Dermatology.
https://doi.org/10.1016/j.jid.2020.06.037
Wang, A., Toma, M. A., Ma, J., Li, D., Vij, M., Chu, T., Wang, J., Li, X., & Xu Landén, N. (2020). Circular RNA hsa_circ_0084443 Is Upregulated in Diabetic Foot Ulcer and Modulates Keratinocyte Migration and Proliferation. Advances in Wound Care, 9(4), 145–160.
https://doi.org/10.1089/wound.2019.0956
Wu, J., & Landén, N. X. (2020). Investigation of Skin Using a Mouse Model. In Methods in molecular biology (Clifton, N.J.) (Vol. 2154, pp. 239–247).
https://doi.org/10.1007/978-1-0716-0648-3_20
Wu, J., Li, X., Li, D., Ren, X., Li, Y., Herter, E. K., Qian, M., Toma, M.-A., Wintler, A.-M., Sérézal, I. G., Rollman, O., Ståhle, M., Wikstrom, J. D., Ye, X., & Landén, N. X. (2020). MicroRNA-34 Family Enhances Wound Inflammation by Targeting LGR4. Journal of Investigative Dermatology, 140(2), 465-476.e11.
https://doi.org/10.1016/j.jid.2019.07.694
Herter, E. K., Li, D., Toma, M. A., Vij, M., Li, X., Visscher, D., Wang, A., Chu, T., Sommar, P., Blomqvist, L., Berglund, D., Ståhle, M., Wikstrom, J. D., & Xu Landén, N. (2019). WAKMAR2, a Long Noncoding RNA Downregulated in Human Chronic Wounds, Modulates Keratinocyte Motility and Production of Inflammatory Chemokines. Journal of Investigative Dermatology, 139(6), 1373–1384.
https://doi.org/10.1016/j.jid.2018.11.033
Li, D., Kular, L., Vij, M., Herter, E. K., Li, X., Wang, A., Chu, T., Toma, M.-A., Zhang, L., Liapi, E., Mota, A., Blomqvist, L., Sérézal, I. G., Rollman, O., Wikstrom, J. D., Bienko, M., Berglund, D., Ståhle, M., Sommar, P., … Landén, N. X. (2019). Human skin long noncoding RNA WAKMAR1 regulates wound healing by enhancing keratinocyte migration. Proceedings of the National Academy of Sciences, 116(19), 9443–9452.
https://doi.org/10.1073/pnas.1814097116
Herter, E. K., & Xu Landén, N. (2017). Non-Coding RNAs: New Players in Skin Wound Healing. Advances in Wound Care, 6(3), 93–107.
https://doi.org/10.1089/wound.2016.0711
Li, D., & Landén, N. X. (2017). MicroRNAs in skin wound healing. European Journal of Dermatology : EJD, 27(S1), 12–14.
https://doi.org/10.1684/ejd.2017.3040
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