MWLC Publications

The publications from Ming Wai Lau Centre for Reparative Medicine reflect collaborative efforts both within and outside of KI. The selected publications are sorted by researchers.

Gonçalo Castelo-Branco

Bonetti, A., Agostini, F., Suzuki, A. M., Hashimoto, K., Pascarella, G., Gimenez, J., Roos, L., Nash, A. J., Ghilotti, M., Cameron, C. J. F., Valentine, M., Medvedeva, Y. A., Noguchi, S., Agirre, E., Kashi, K., Samudyata, Luginbühl, J., Cazzoli, R., Agrawal, S., … Carninci, P. (2020). RADICL-seq identifies general and cell type–specific principles of genome-wide RNA-chromatin interactions. Nature Communications, 11(1), 1018.
https://doi.org/10.1038/s41467-020-14337-6

Marisca, R., Hoche, T., Agirre, E., Hoodless, L. J., Barkey, W., Auer, F., Castelo-Branco, G., & Czopka, T. (2020). Functionally distinct subgroups of oligodendrocyte precursor cells integrate neural activity and execute myelin formation. Nature Neuroscience, 23(3), 363–374.
https://doi.org/10.1038/s41593-019-0581-2

Samudyata, Castelo-Branco, G., & Liu, J. (2020). Epigenetic regulation of oligodendrocyte differentiation: From development to demyelinating disorders. GLIA, 68(8), 1619–1630.
https://doi.org/10.1002/glia.23820

Falcão, A. M., Meijer, M., Scaglione, A., Rinwa, P., Agirre, E., Liang, J., Larsen, S. C., Heskol, A., Frawley, R., Klingener, M., Varas-Godoy, M., Raposo, A. A. S. F., Ernfors, P., Castro, D. S., Nielsen, M. L., Casaccia, P., & Castelo-Branco, G. (2019). PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination. Cell Reports, 27(4), 1090-1102.e10.
https://doi.org/10.1016/j.celrep.2019.03.108

Floriddia, E. M., & Castelo-Branco, G. (2019). Ancestry Tracing: Uncovering a Gliomagenesis Master Regulator. Cell Stem Cell, 24(5), 677–679.
https://doi.org/10.1016/j.stem.2019.04.006

Jäkel, S., Agirre, E., Mendanha Falcão, A., van Bruggen, D., Lee, K. W., Knuesel, I., Malhotra, D., Ffrench-Constant, C., Williams, A., & Castelo-Branco, G. (2019). Altered human oligodendrocyte heterogeneity in multiple sclerosis. Nature, 566(7745), 543–547.
https://doi.org/10.1038/s41586-019-0903-2

Kupari, J., Häring, M., Agirre, E., Castelo-Branco, G., & Ernfors, P. (2019). An Atlas of Vagal Sensory Neurons and Their Molecular Specialization. Cell Reports, 27(8), 2508-2523.e4.
https://doi.org/10.1016/j.celrep.2019.04.096

Marques, S., van Bruggen, D., & Castelo-Branco, G. (2019). Single-Cell RNA Sequencing of Oligodendrocyte Lineage Cells from the Mouse Central Nervous System. Methods in Molecular Biology (Clifton, N.J.), 1936, 1–21.
https://doi.org/10.1007/978-1-4939-9072-6_1

Samudyata, Amaral, P. P., Engström, P. G., Robson, S. C., Nielsen, M. L., Kouzarides, T., & Castelo-Branco, G. (2019). Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells. Experimental Cell Research, 381(1), 129–138.
https://doi.org/10.1016/j.yexcr.2019.05.006

Falcão, A. M., van Bruggen, D., Marques, S., Meijer, M., Jäkel, S., Agirre, E., Samudyata, Floriddia, E. M., Vanichkina, D. P., Ffrench-Constant, C., Williams, A., Guerreiro-Cacais, A. O., & Castelo-Branco, G. (2018). Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis. Nature Medicine, 24(12), 1837–1844.
https://doi.org/10.1038/s41591-018-0236-y

La Manno, G., Soldatov, R., Zeisel, A., Braun, E., Hochgerner, H., Petukhov, V., Lidschreiber, K., Kastriti, M. E., Lönnerberg, P., Furlan, A., Fan, J., Borm, L. E., Liu, Z., van Bruggen, D., Guo, J., He, X., Barker, R., Sundström, E., Castelo-Branco, G., … Kharchenko, P. V. (2018). RNA velocity of single cells. Nature, 560(7719), 494–498.
https://doi.org/10.1038/s41586-018-0414-6

Marques, S., van Bruggen, D., Vanichkina, D. P., Floriddia, E. M., Munguba, H., Väremo, L., Giacomello, S., Falcão, A. M., Meijer, M., Björklund, Å. K., Hjerling-Leffler, J., Taft, R. J., & Castelo-Branco, G. (2018). Transcriptional Convergence of Oligodendrocyte Lineage Progenitors during Development. Developmental Cell, 46(4), 504-517.e7.
https://doi.org/10.1016/j.devcel.2018.07.005

Samudyata, Castelo-Branco, G., & Bonetti, A. (2018). Birth, coming of age and death: The intriguing life of long noncoding RNAs. Seminars in Cell & Developmental Biology, 79, 143–152.
https://doi.org/10.1016/j.semcdb.2017.11.012

 

Sijie Chen

Gao, H., Kam, C., Chou, T. Y., Wu, M.-Y., Zhao, X., & Chen, S. (2020). A simple yet effective AIE-based fluorescent nano-thermometer for temperature mapping in living cells using fluorescence lifetime imaging microscopy. Nanoscale Horizons5(3), 488–494.
https://doi.org/10.1039/C9NH00693A

Huang, L., Xu, S., Wang, Z., Xue, K., Su, J., Song, Y., Chen, S., Zhu, C., Tang, B. Z., & Ye, R. (2020). Self-Reporting and Photothermally Enhanced Rapid Bacterial Killing on a  Laser-Induced Graphene Mask. ACS Nano, 14(9), 12045–12053.
https://doi.org/10.1021/acsnano.0c05330

Liu, C., Wang, X., Liu, J., Yue, Q., Chen, S., Lam, J. W. Y., Luo, L., & Tang, B. Z. (2020). Near-Infrared AIE Dots with Chemiluminescence for Deep-Tissue Imaging. Advanced Materials, 32(43), 2004685.
https://doi.org/https://doi.org/10.1002/adma.202004685

Lv, W., Long, K., Yang, Y., Chen, S., Zhan, C., & Wang, W. (2020). A Red Light-Triggered Drug Release System Based on One-Photon Upconversion-Like Photolysis. Advanced Healthcare Materials, 9(21), 2001118.
https://doi.org/https://doi.org/10.1002/adhm.202001118

OwYong, T. C., Ding, S., Wu, N., Fellowes, T., Chen, S., White, J. M., Wong, W. W. H., & Hong, Y. (2020). Optimising molecular rotors to AIE fluorophores for mitochondria uptake and retention. Chemical Communications, 56(94), 14853–14856.
https://doi.org/10.1039/D0CC06411D

Wu, M., Leung, J., Liu, L., Kam, C., Chan, K. Y. K., Li, R. A., Feng, S., & Chen, S. (2020). A Small‐Molecule AIE Chromosome Periphery Probe for Cytogenetic Studies. Angewandte Chemie International Edition59(26), 10327–10331.
https://doi.org/10.1002/anie.201916718

Xu, W., Zhang, Z., Kang, M., Guo, H., Li, Y., Wen, H., Lee, M. M. S., Wang, Z., Kwok, R. T. K., Lam, J. W. Y., Li, K., Xi, L., Chen, S., Wang, D., & Tang, B. Z. (2020). Making the Best Use of Excited-State Energy: Multimodality Theranostic Systems Based on Second Near-Infrared (NIR-II) Aggregation-Induced Emission Luminogens (AIEgens). ACS Materials Letters, 2(8), 1033–1040.
https://doi.org/10.1021/acsmaterialslett.0c00263

Zhao, E., Lai, P., Xu, Y., Zhang, G., & Chen, S. (2020). Fluorescent Materials With Aggregation-Induced Emission Characteristics for Array-Based Sensing Assay. Frontiers in Chemistry8, 288.
https://doi.org/10.3389/fchem.2020.00288

Gu, M., Zeng, Z., Wu, M., Leung, J., Zhao, E., Wang, S., & Chen, S. (2019). Imaging Macrophage Phagocytosis Using AIE Luminogen‐Labeled E. coli. Chemistry – An Asian Journal, 14(6), 775–780.
https://doi.org/10.1002/asia.201801859

Hoffecker, I. T., Chen, S., Gådin, A., Bosco, A., Teixeira, A. I., & Högberg, B. (2019). Solution-Controlled Conformational Switching of an Anchored Wireframe DNA Nanostructure. Small, 15(1), 1803628.
https://doi.org/10.1002/smll.201803628

Li, F., Han, J., Cao, T., Lam, W., Fan, B., Tang, W., Chen, S., Fok, K. L., & Li, L. (2019). Design of self-assembly dipeptide hydrogels and machine learning via their chemical features. Proceedings of the National Academy of Sciences, 116(23), 11259–11264.
https://doi.org/10.1073/pnas.1903376116

Liu, L., Zou, Q., Leung, J.-K., Wang, J.-L., Kam, C., Chen, S., Feng, S., & Wu, M.-Y. (2019). Ultrafast labeling and high-fidelity imaging of mitochondria in cancer cells using an aggregation-enhanced emission fluorescent probe. Chemical Communications, 55(97), 14681–14684.
https://doi.org/10.1039/C9CC07775H

Tu, Y., Yu, Y., Zhou, Z., Xie, S., Yao, B., Guan, S., Situ, B., Liu, Y., Kwok, R. T. K., Lam, J. W. Y., Chen, S., Huang, X., Zeng, Z., & Tang, B. Z. (2019). Specific and Quantitative Detection of Albumin in Biological Fluids by Tetrazolate-Functionalized Water-Soluble AIEgens. ACS Applied Materials & Interfaces, 11(33), 29619–29629.
https://doi.org/10.1021/acsami.9b10359

Wong, A. Y. H., Xie, S., Tang, B. Z., & Chen, S. (2019). Fluorescent Silver Staining of Proteins in Polyacrylamide Gels. Journal of Visualized Experiments, 146.
https://doi.org/10.3791/58669

Xie, S., Wong, A. Y. H., Chen, S., & Tang, B. Z. (2019). Fluorogenic Detection and Characterization of Proteins by Aggregation-Induced Emission Methods. Chemistry (Weinheim an Der Bergstrasse, Germany), 25(23), 5824–5847.
https://doi.org/10.1002/chem.201805297

Chen, S., Liu, J., Zhang, S., Zhao, E., Yu, C. Y. Y., Hushiarian, R., Hong, Y., & Tang, B. Z. (2018). Biochromic silole derivatives: a single dye for differentiation, quantitation and imaging of live/dead cells. Materials Horizons, 5(5), 969–978.
https://doi.org/10.1039/C8MH00799C

Gao, H., Zhao, X., & Chen, S. (2018). AIEgen-Based Fluorescent Nanomaterials: Fabrication and Biological Applications. Molecules, 23(2), 419.
https://doi.org/10.3390/molecules23020419

Xie, S., Wong, A. Y. H., Kwok, R. T. K., Li, Y., Su, H., Lam, J. W. Y., Chen, S., & Tang, B. Z. (2018). Fluorogenic Ag + -Tetrazolate Aggregation Enables Efficient Fluorescent Biological Silver Staining. Angewandte Chemie International Edition, 57(20), 5750–5753.
https://doi.org/10.1002/anie.201801653

 

Simon Elsässer

Lafranchi, L., Schlesinger, D., Kimler, K. J., & Elsässer, S. J. (2020). Universal Single-Residue Terminal Labels for Fluorescent Live Cell Imaging of Microproteins. Journal of the American Chemical Society, jacs.0c09574.
https://doi.org/10.1021/jacs.0c09574

Meineke, B., Heimgärtner, J., Eirich, J., Landreh, M., & Elsässer, S. J. (2020). Site-Specific Incorporation of Two ncAAs for Two-Color Bioorthogonal Labeling and Crosslinking of Proteins on Live Mammalian Cells. Cell Reports, 31(12), 107811.
https://doi.org/10.1016/j.celrep.2020.107811

Navarro, C., Lyu, J., Katsori, A.-M., Caridha, R., & Elsässer, S. J. (2020). An embryonic stem cell-specific heterochromatin state promotes core histone exchange in the absence of DNA accessibility. Nature Communications, 11(1), 5095.
https://doi.org/10.1038/s41467-020-18863-1

Pesic, M., Egamberdieva, D., Kolodziejczyk, B., Elsässer, S. J., Neergheen, V. S., & Kagansky, A. (2020). Towards policies that capture the expected value of biomolecular diversity for drug discovery, human health, and well-being. Biologia Futura.
https://doi.org/10.1007/s42977-020-00043-3

Kumar, B., & Elsässer, S. (2019). Quantitative multiplexed ChIP reveals global alterations that shape promoter bivalency in ground state embryonic stem cells. Cell Reports.
https://doi.org/10.1101/557082

van Husen, L. S., Schedin-Weiss, S., Trung, M. N., Kazmi, M. A., Winblad, B., Sakmar, T. P., Elsässer, S. J., & Tjernberg, L. O. (2019). Dual Bioorthogonal Labeling of the Amyloid-β Protein Precursor Facilitates Simultaneous Visualization of the Protein and Its Cleavage Products. Journal of Alzheimer’s Disease, 72(2), 537–548.
https://doi.org/10.3233/JAD-190898

Elsässer, S. J. (2018). Generation of Stable Amber Suppression Cell Lines. In Methods in Molecular Biology (pp. 237–245).
https://doi.org/10.1007/978-1-4939-7574-7_15

Meineke, B., Heimgärtner, J., Lafranchi, L., & Elsässer, S. J. (2018). Methanomethylophilus alvus Mx1201 Provides Basis for Mutual Orthogonal Pyrrolysyl tRNA/Aminoacyl-tRNA Synthetase Pairs in Mammalian Cells. ACS Chemical Biology, 13(11), 3087–3096.
https://doi.org/10.1021/acschembio.8b00571

Neergheen-Bhujun, V., Awan, A. T., Baran, Y., Bunnefeld, N., Chan, K., dela Cruz, T. E., Egamberdieva, D., Elsässer, S., Johnson, M. V., Komai, S., Konevega, A. L., Malone, J. H., Mason, P., Nguon, R., Piper, R., Shrestha, U. B., Pešić, M., & Kagansky, A. (2017). Biodiversity, drug discovery, and the future of global health: Introducing the biodiversity to biomedicine consortium, a call to action. Journal of Global Health, 7(2).
https://doi.org/10.7189/jogh.07.020304

 

Christian Göritz

Dias, D. O., & Göritz, C. (2018). Fibrotic scarring following lesions to the central nervous system. Matrix Biology, 6869, 561–570.
https://doi.org/10.1016/j.matbio.2018.02.009

Dias, D. O., Kim, H., Holl, D., Werne Solnestam, B., Lundeberg, J., Carlén, M., Göritz, C., & Frisén, J. (2018). Reducing Pericyte-Derived Scarring Promotes Recovery after Spinal Cord Injury. Cell, 173(1), 153-165.e22.
https://doi.org/10.1016/j.cell.2018.02.004

Reichenbach, B., Classon, J., Aida, T., Tanaka, K., Genander, M., & Göritz, C. (2018). Glutamate transporter Slc1a3 mediates inter‐niche stem cell activation during skin growth. The EMBO Journal, 37(9).
https://doi.org/10.15252/embj.201798280

 

Francois Lallemend

Faure, L., Wang, Y., Kastriti, M. E., Fontanet, P., Cheung, K. K. Y., Petitpré, C., Wu, H., Sun, L. L., Runge, K., Croci, L., Landy, M. A., Lai, H. C., Consalez, G. G., de Chevigny, A., Lallemend, F., Adameyko, I., & Hadjab, S. (2020). Single cell RNA sequencing identifies early diversity of sensory neurons forming via bi-potential intermediates. Nature Communications, 11(1), 4175.
https://doi.org/10.1038/s41467-020-17929-4

Romanov, R. A., Tretiakov, E. O., Kastriti, M. E., Zupancic, M., Häring, M., Korchynska, S., Popadin, K., Benevento, M., Rebernik, P., Lallemend, F., Nishimori, K., Clotman, F., Andrews, W. D., Parnavelas, J. G., Farlik, M., Bock, C., Adameyko, I., Hökfelt, T., Keimpema, E., & Harkany, T. (2020). Molecular design of hypothalamus development. Nature, 582(7811), 246–252.
https://doi.org/10.1038/s41586-020-2266-0

Bartesaghi, L., Wang, Y., Fontanet, P., Wanderoy, S., Berger, F., Wu, H., Akkuratova, N., Bouçanova, F., Médard, J. J., Petitpré, C., Landy, M. A., Zhang, M. D., Harrer, P., Stendel, C., Stucka, R., Dusl, M., Kastriti, M. E., Croci, L., Lai, H. C., … Chrast, R. (2019). PRDM12 Is Required for Initiation of the Nociceptive Neuron Lineage during Neurogenesis. Cell Reports, 26(13), 3484-3492.e4.
https://doi.org/10.1016/j.celrep.2019.02.098

Wang, Y., Wu, H., Fontanet, P., Codeluppi, S., Akkuratova, N., Petitpré, C., Xue-Franzén, Y., Niederreither, K., Sharma, A., Da Silva, F., Comai, G., Agirman, G., Palumberi, D., Linnarsson, S., Adameyko, I., Moqrich, A., Schedl, A., La Manno, G., Hadjab, S., & Lallemend, F. (2019). A cell fitness selection model for neuronal survival during development. Nature Communications, 10(1), 4137.
https://doi.org/10.1038/s41467-019-12119-3

Wang, Y., Wu, H., Zelenin, P., Fontanet, P., Wanderoy, S., Petitpré, C., Comai, G., Bellardita, C., Xue-Franzén, Y., Huettl, R. E., Huber, A. B., Tajbakhsh, S., Kiehn, O., Ernfors, P., Deliagina, T. G., Lallemend, F., & Hadjab, S. (2019). Muscle-selective RUNX3 dependence of sensorimotor circuit development. Development (Cambridge), 146(20).
https://doi.org/10.1242/dev.181750

Petitpré, C., Wu, H., Sharma, A., Tokarska, A., Fontanet, P., Wang, Y., Helmbacher, F., Yackle, K., Silberberg, G., Hadjab, S., & Lallemend, F. (2018). Neuronal heterogeneity and stereotyped connectivity in the auditory afferent system. Nature Communications, 9(1), 3691.
https://doi.org/10.1038/s41467-018-06033-3

Furlan, A., Dyachuk, V., Kastriti, M. E., Calvo-Enrique, L., Abdo, H., Hadjab, S., Chontorotzea, T., Akkuratova, N., Usoskin, D., Kamenev, D., Petersen, J., Sunadome, K., Memic, F., Marklund, U., Fried, K., Topilko, P., Lallemend, F., Kharchenko, P. V., Ernfors, P., & Adameyko, I. (2017). Multipotent peripheral glial cells generate neuroendocrine cells of the adrenal medulla. Science, 357, 6346.
https://doi.org/10.1126/science.aal3753

Peng, C., Li, L., Zhang, M. D., Gonzales, C. B., Parisien, M., Belfer, I., Usoskin, D., Abdo, H., Furlan, A., Häring, M., Lallemend, F., Harkany, T., Diatchenko, L., Hökfelt, T., Hjerling-Leffler, J., & Ernfors, P. (2017). MIR-183 cluster scales mechanical pain sensitivity by regulating basal and neuropathic pain genes. Science, 356(6343), 1168–1171.
https://doi.org/10.1126/science.aam7671

 

Ning Xu Landén

Li D, Peng H, Qu L, Sommar P, Wang A, Chu T, Li X, Bi X, Liu Q, Sérézal IG, Rollman O, Lohcharoenkal W, Zheng X, Angelstig SE, Grünler J, Pivarcsi A, Sonkoly E, Catrina S-B, Xiao C, Ståhle M, Mi Q-S, Zhou L&Landén, N. X. (2020). miR-19a/b and miR-20a promote wound healing by regulating the inflammatory response of keratinocytes. Journal of Investigative Dermatology.
https://doi.org/10.1016/j.jid.2020.06.037

Wang, A., Toma, M. A., Ma, J., Li, D., Vij, M., Chu, T., Wang, J., Li, X., & Xu Landén, N. (2020). Circular RNA hsa_circ_0084443 Is Upregulated in Diabetic Foot Ulcer and Modulates Keratinocyte Migration and Proliferation. Advances in Wound Care, 9(4), 145–160.
https://doi.org/10.1089/wound.2019.0956

Wu, J., & Landén, N. X. (2020). Investigation of Skin Using a Mouse Model. In Methods in molecular biology (Clifton, N.J.) (Vol. 2154, pp. 239–247).
https://doi.org/10.1007/978-1-0716-0648-3_20

Wu, J., Li, X., Li, D., Ren, X., Li, Y., Herter, E. K., Qian, M., Toma, M.-A., Wintler, A.-M., Sérézal, I. G., Rollman, O., Ståhle, M., Wikstrom, J. D., Ye, X., & Landén, N. X. (2020). MicroRNA-34 Family Enhances Wound Inflammation by Targeting LGR4. Journal of Investigative Dermatology, 140(2), 465-476.e11.
https://doi.org/10.1016/j.jid.2019.07.694

Herter, E. K., Li, D., Toma, M. A., Vij, M., Li, X., Visscher, D., Wang, A., Chu, T., Sommar, P., Blomqvist, L., Berglund, D., Ståhle, M., Wikstrom, J. D., & Xu Landén, N. (2019). WAKMAR2, a Long Noncoding RNA Downregulated in Human Chronic Wounds, Modulates Keratinocyte Motility and Production of Inflammatory Chemokines. Journal of Investigative Dermatology, 139(6), 1373–1384.
https://doi.org/10.1016/j.jid.2018.11.033

Li, D., Kular, L., Vij, M., Herter, E. K., Li, X., Wang, A., Chu, T., Toma, M.-A., Zhang, L., Liapi, E., Mota, A., Blomqvist, L., Sérézal, I. G., Rollman, O., Wikstrom, J. D., Bienko, M., Berglund, D., Ståhle, M., Sommar, P., … Landén, N. X. (2019). Human skin long noncoding RNA WAKMAR1 regulates wound healing by enhancing keratinocyte migration. Proceedings of the National Academy of Sciences, 116(19), 9443–9452.
https://doi.org/10.1073/pnas.1814097116

Herter, E. K., & Xu Landén, N. (2017). Non-Coding RNAs: New Players in Skin Wound Healing. Advances in Wound Care, 6(3), 93–107.
https://doi.org/10.1089/wound.2016.0711

Li, D., & Landén, N. X. (2017). MicroRNAs in skin wound healing. European Journal of Dermatology : EJD, 27(S1), 12–14.
https://doi.org/10.1684/ejd.2017.3040

Li, X., Li, D., Wang, A., Chu, T., Lohcharoenkal, W., Zheng, X., Grünler, J., Narayanan, S., Eliasson, S., Herter, E. K., Wang, Y., Ma, Y., Ehrström, M., Eidsmo, L., Kasper, M., Pivarcsi, A., Sonkoly, E., Catrina, S.-B., Ståhle, M., & Xu Landén, N. (2017). MicroRNA-132 with Therapeutic Potential in Chronic Wounds. Journal of Investigative Dermatology, 137(12), 2630–2638.
https://doi.org/10.1016/j.jid.2017.08.003

Li, X., Li, D., Wikstrom, J. D., Pivarcsi, A., Sonkoly, E., Ståhle, M., & Landén, N. X. (2017). MicroRNA-132 promotes fibroblast migration via regulating RAS p21 protein activator 1 in skin wound healing. Scientific Reports, 7(1), 7797.
https://doi.org/10.1038/s41598-017-07513-0

 

Fredrik Lanner

Petrus-Reurer, S., Kumar, P., Padrell Sánchez, S., Aronsson, M., André, H., Bartuma, H., Plaza Reyes, A., Nandrot, E. F., Kvanta, A., & Lanner, F. (2020). Preclinical safety studies of human embryonic stem cell-derived retinal pigment epithelial cells for the treatment of age-related macular degeneration. Stem Cells Translational Medicine, 9(8), 936–953.
https://doi.org/10.1002/sctm.19-0396

Petrus-Reurer, S., Winblad, N., Kumar, P., Gorchs, L., Chrobok, M., Wagner, A. K., Bartuma, H., Lardner, E., Aronsson, M., Plaza Reyes, Á., André, H., Alici, E., Kaipe, H., Kvanta, A., & Lanner, F. (2020). Generation of Retinal Pigment Epithelial Cells Derived from Human Embryonic Stem Cells Lacking Human Leukocyte Antigen Class I and II. Stem Cell Reports, 14(4), 648–662.
https://doi.org/10.1016/j.stemcr.2020.02.006

Plaza Reyes, A., Petrus-Reurer, S., Padrell Sánchez, S., Kumar, P., Douagi, I., Bartuma, H., Aronsson, M., Westman, S., Lardner, E., André, H., Falk, A., Nandrot, E. F., Kvanta, A., & Lanner, F. (2020). Identification of cell surface markers and establishment of monolayer differentiation to retinal pigment epithelial cells. Nature Communications, 11, 1609.
https://doi.org/10.1038/s41467-020-15326-5

Wagner, M., Yoshihara, M., Douagi, I., Damdimopoulos, A., Panula, S., Petropoulos, S., Lu, H., Pettersson, K., Palm, K., Katayama, S., Hovatta, O., Kere, J., Lanner, F., & Damdimopoulou, P. (2020). Single-cell analysis of human ovarian cortex identifies distinct cell populations but no oogonial stem cells. Nature Communications, 11(1), 1147.
https://doi.org/10.1038/s41467-020-14936-3

Gelali, E., Girelli, G., Matsumoto, M., Wernersson, E., Custodio, J., Mota, A., Schweitzer, M., Ferenc, K., Li, X., Mirzazadeh, R., Agostini, F., Schell, J. P., Lanner, F., Crosetto, N., & Bienko, M. (2019). iFISH is a publically available resource enabling versatile DNA FISH to study genome architecture. Nature Communications, 10(1), 1636.
https://doi.org/10.1038/s41467-019-09616-w

Wagner, M., Yoshihara, M., Douagi, I., Damdimopoulos, A., Panula, S., Petropoulos, S., Lu, H., Pettersson, K., Palm, K., Katayama, S., Hovatta, O., Kere, J., Lanner, F., & Damdimopoulou, P. (2019). Single cell map of the human ovarian cortex. BioRxiv.
https://doi.org/10.1101/791343

Ortega, N. M., Winblad, N., Plaza Reyes, A., & Lanner, F. (2018). Functional genetics of early human development. Current Opinion in Genetics and Development, 52, 1–6.
https://doi.org/10.1016/j.gde.2018.04.005

Petrus-Reurer, S., Bartuma, H., Aronsson, M., Westman, S., Lanner, F., & Kvanta, A. (2018). Subretinal transplantation of human embryonic stem cell derived-retinal pigment epithelial cells into a large-eyed model of geographic atrophy. Journal of Visualized Experiments, 131.
https://doi.org/10.3791/56702

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Linxian Li

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Ronald Li

Chow, M. Z.-Y., Sadrian, S. N., Keung, W., Geng, L., Ren, L., Kong, C.-W., Wong, A. O.-T., Hulot, J.-S., Chen, C. S., Costa, K. D., Hajjar, R. J., & Li, R. A. (2019). Modulation of chromatin remodeling proteins SMYD1 and SMARCD1 promotes contractile function of human pluripotent stem cell-derived ventricular cardiomyocyte in 3D-engineered cardiac tissues. Scientific Reports, 9(1), 7502.
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Dongan Wang

Dong, Z., Meng, X., Yang, W., Zhang, J., Sun, P., Zhang, H., Fang, X., Wang, D.-A., & Fan, C. (2021). Progress of gelatin-based microspheres (GMSs) as delivery vehicles of drug and cell. Materials Science and Engineering: C, 122, 111949.
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Zongli Zheng

Wan, Y. C. E., Leung, T. C. S., Ding, D., Sun, X., Liu, J., Zhu, L., Kang, T. Z. E., Yang, D., Zhang, Y., Zhang, J., Qian, C., Huen, M. S. Y., Li, Q., Chow, M. Z. Y., Zheng, Z., Han, J., Goel, A., Wang, X., Ishibashi, T., & Chan, K. M. (2020). Cancer-associated histone mutation H2BG53D disrupts DNA–histone octamer interaction and promotes oncogenic phenotypes. Signal Transduction and Targeted Therapy, 5(1), 27.
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Choi, G. C. G., Zhou, P., Yuen, C. T. L., Chan, B. K. C., Xu, F., Bao, S., Chu, H. Y., Thean, D., Tan, K., Wong, K. H., Zheng, Z., & Wong, A. S. L. (2019). Combinatorial mutagenesis en masse optimizes the genome editing activities of SpCas9. Nature Methods, 16(8), 722–730.
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