Sijie Chen

Dr. Sijie Chen is an Assistant Professor at Ming Wai Lau Centre for Reparative Medicine, KI, in Hong Kong.

Dr. Sijie Chen

Biographical

Dr. Sijie Chen received her BSc in Biology from Wuhan University in 2009 and PhD in Bioengineering from Hong Kong University of Science and Technology (HKUST) in 2013, under the supervision of Prof Ben Zhong Tang. She worked as a Postdoctoral Fellow in HKUST and then as an Endeavour Fellow in University of Melbourne and a visiting scientist in Walter and Eliza Hall Institute of Medical Research. She joined Prof Ana Teixeira’s group as a Postdoc in the Division of Biomaterials and Regenerative Medicine at the Department of Medical Biochemistry and Biophysics in Karolinska Institutet (KI) since late 2015.

Dr Chen was earlier working on fluorescent biosensors, fluorescence imaging and nanomaterials. She has published 55 scientific papers, more than ten of which were published after she joined MWLC and with the Centre’s support.

 

Research

Dr. Sijie Chen's current research interests focus on the development of new luminescent materials and novel methods for studying the biological events, especially fluorescent tools for mechanobiology research.

 

Group Members

Lab members
Name Title/Position
Sijie Chen Assistant Professor
Fei Wang Postdoctoral Researcher
Quanzhi Yang Postdoctoral Researcher
Steven Zhao Postdoctoral Researcher
Chuen Kam Research Officer
Xueli Zhang Research Assistant
Alex Wong PhD Student

Previous lab members

  • Dr Hui Gao, 2017-2019; Ph.D., Queen Mary University of London, UK; before join KI: The University of Leeds. Recipient of Thousand Young Talents Program (2018). 2019-now, Professor, Beihang University. 
  • Dr Fei Li,  2017-2019, Co-supervised with Dr Linxian Li, MWLC, KI; Ph.D., Nanjing University, China. 2019-now, Associate Professor, China Pharmaceutical University.   
  • Dr Sheng Xie, 2017-2019; Ph.D., Royal Institute of Technology, Sweden; before join KI: HKUST. Recipient of International Postdoc Grant (2018-2019). 2020-now, Professor, Hunan University. 
  • Ms Chloe Lee, Research Assistant, 2018-2020; MSc, The University of Manchester, UK. 2020.10-now, Research Associate, Lee's Pharm Genomics Lab Limited, Hong Kong
  • Dr Yupeng Shi, Postdoctoral Researcher, 2020; Ph.D., Sorbonne University, France; 2021-now, Research associate professor, Zhengzhou University.
  • Dr Mingyu Wu, Postdoctoral Researcher, 2018-2021.
  • Mr Miller Leung, Research Assistant, 2018-2021.
  • Ms Renee Chou, Research Assistant, 2019-2021.
  • Dr Blake Ho, Postdoctoral Researcher, 2019-2021.

Selected Publications

Full list: Google Scholar

Wu, M.-Y., Wong, A. Y. H., Leung, J.-K., Kam, C., Wu, K. L.-K., Chan, Y.-S., Liu, K., Ip, N. Y., & Chen, S. (2021). A near-infrared AIE fluorescent probe for myelin imaging: From sciatic nerve to the optically cleared brain tissue in 3D. Proceedings of the National Academy of Sciences, 118 (45) e2106143118.
https://doi.org/10.1073/pnas.2106143118

Wu, M.-Y., Gu, M., Leung, J.-K., Li, X., Yuan, Y., Shen, C., Wang, L., Zhao, E., & Chen, S. (2021). A Membrane-Targeting Photosensitizer with Aggregation-Induced Emission Characteristics for Highly Efficient Photodynamic Combat of Human Coronaviruses. Small, 17(30), 2101770.
https://doi.org/10.1002/smll.202101770

Ho, P.-Y., Lee, S.-Y., Kam, C., Zhu, J., Shan, G.-G., Hong, Y., Wong, W.-Y., & Chen, S., (2021). Fluorescence Imaging and Photodynamic Inactivation of Bacteria Based on Cationic Cyclometalated Iridium(III) Complexes with Aggregation-Induced Emission Properties. Adv. Healthcare Mater. 2100706. 
https://doi.org/10.1002/adhm.202100706

Zhao, E., Kam, C., Wu, M., Wang, E., Wang, J., Tang, B. Z., & Chen, S. (2021). An Aggregation-Induced Emission Optical Highlighter for the Studies of Endoplasmic Reticulum-Lipid Droplet Content Dynamics. CCS Chemistry.
https://doi.org/10.31635/ccschem.021.202101143

Wu, M., Leung, J., Liu, L., Kam, C., Chan, K. Y. K., Li, R. A., Feng, S., & Chen, S. (2020). A Small‐Molecule AIE Chromosome Periphery Probe for Cytogenetic Studies. Angewandte Chemie International Edition, 59(26), 10327–10331. 
https://doi.org/10.1002/anie.201916718