NextGenNK
NextGenNK is a Competence Center for the development of next generation NK cell-based cancer immunotherapies. The Center is coordinated by Karolinska Institutet and collaborates with the Karolinska University Hospital and prominent national and international industrial partners. The Center was launched in 2020, and is jointly funded by Vinnova, KI, and the Industrial partners.
News
Upcoming events
Sweden’s Minister of Higher Education and Research visits KI
On February 1, 2023, Sweden’s new Minister of Higher Eduction and Research, Mats Persson, visted KI. During the visit, NextGenNK’s Director Hans-Gustaf Ljunggren presented the NextGenNK Competence Center and discussed the importance of interactions between academia, health care and industry in the development of new cellular therapies against cancer.
”Stem-cell-a-thon” Seminar Series
The Center for Hematology and Regenerative Medicine (HERM) is organizing a seminar series by distinguished national and international speakers from the field of Stem Cell Biology and Regenerative Medicine.
The seminars are supported by SFO- Strategic research area in stem cells and regenerative medicine and NextGenNK.
Podcast: NK cell-based cancer immunotherapies
A podcast about NK cell-based cancer immunotherapies with Evren Alici and Hans-Gustaf Ljunggren.
Awards and recognitions
Arnika Wagner - KID funding
Arnika Wagner, assistant professor at Karolinska Institutet, was granted KID funding for a new PhD student.
Nutsa Burduli - Best Oral Presentation
Nutsa Burduli, PhD student at Karolinska Institutet was awarded Best Oral Presentation at Tissue & Motion Conference 2022, Djurönäset, Sweden.
Katharina Susek - Best Oral Presentation
Katharina Susek, PhD student at Karolinska Institutet was awarded Best Oral Presentation at Collaboration in Science 2022, Flemingsberg, Sweden.
Selected Publications
Adaptive single-KIR+NKG2C+ NK cells expanded from select superdonors show potent missing-self reactivity and efficiently control HLA-mismatched acute myeloid leukemia
Haroun-Izquierdo A. et al, J Immunother Cancer, 2022
Generation of NK cells with chimeric-switch receptors to overcome PD1-mediated inhibition in cancer immunotherapy
Susek KH et al, Cancer Immunol Immunother, 2022
A tractable microscopy- and flow cytometry-based method to measure natural killer cell-mediated killing and infiltration of tumor spheroids
Schwietzer et al, Methods in Cell Biology, 2022