NextGenNK
NextGenNK is a Competence Center for the development of next generation NK cell-based cancer immunotherapies. The Center is coordinated by Karolinska Institutet and collaborates with the Karolinska University Hospital and prominent national and international industrial partners. The Center was launched in 2020, and is jointly funded by Vinnova, KI, and the Industrial partners.
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Awards and recognitions
Awards and recognitions
NextGenNK congratulates
Katharina Susek on the IMS Young Investigator Award
Maria Karvouni on the IMS Young Investigator Award
Arnika Wagner on the EHA Research Grant
NextGenNK researchers at InCheck kick-off
NextGenNK researchers at InCheck kick-off
In early July, three NextGenNK researchers participated in the kick-off retreat for InCheck “Innate Immune Checkpoints in Cancer and Tissue Damage" in Heidelberg, Germany. InCheck’s focus is to uncover checkpoints in innate immune cells at the transcriptional, post- transcriptional, metabolic and cell-surface receptor levels, and to validate their functions in cancer and conditions of tissue damage.
New method for high-content screening of drug and immune cell sensitivity of cancer cells
New method for high-content screening of drug and immune cell sensitivity of cancer cells
The lab of Björn Önfelt has developed a miniaturized method for high-content screening of drug and immune cell sensitivity of cancer cells. The miniaturized format allowing long-term cell culture, efficient screening, and high-quality imaging of small sample volumes makes this methodology promising for individualized cytotoxicity tests for precision medicine.
Awards and recognitions
Arnika Wagner - Topic-in-Focus Advanced Research Grant, EHA grant
Arnika Wagner - Topic-in-Focus Advanced Research Grant, EHA grant
Arnika Wagner, assistant professor at Karolinska Institutet, was awarded the Topic-in-Focus Advanced Research Grant.
Katharina Susek - IMS Young Investigator Award for Exemplary Abstract
Katharina Susek - IMS Young Investigator Award for Exemplary Abstract
Katharina Susek, PhD student at Karolinska Institutet was awarded the IMS Young Investigator Award for Exemplary Abstract.
Maria Karvouni - IMS Young Investigator Award for Exemplary Abstract
Maria Karvouni - IMS Young Investigator Award for Exemplary Abstract
Maria Karvouni, PhD student at Karolinska Institutet was awarded the IMS Young Investigator Award for Exemplary Abstract.
Selected Publications
A tractable microscopy- and flow cytometry-based method to measure natural killer cell-mediated killing and infiltration of tumor spheroids
Schwietzer et al, Methods in Cell Biology, 2022
Miniaturized and multiplexed high-content screening of drug and immune sensitivity in a multichambered microwell chip
Sandström et al. Cell Rep Methods. 2022
Autologous NK cells as consolidation therapy following stem cell transplantation in multiple myeloma
Nahi et al. Cell Rep Med. 2022