Karolinska Experimental Research and Imaging Centre (KERIC)

KERIC is a core facility offering different imaging analyses in experimental systems in combination with experimental surgery in large animals like swine as well as in rodents. The unit belongs to the department of comparative medicine (AKM) and is situated at Karolinska University Hospital, Solna. The core facility is financed by Karolinska University Hospital and user fees.

We offer a fully equipped facility for experimental surgery with four full size operation units equipped with ventilators and monitors for physiological functions, and two laboratories for small animal surgery. We provide tools for angiography (Philips XD20), MRI (Varian 9.4T), microPET (Focus 120 camera) and a combined nano PET-MRI/CT (Mediso nanoScan), and offer our resources to both academic research, training courses and for external clients to develop and test new equipment.


The unit for angiography provides a monoplane Philips XD20 including 3D angiography and XperCT. It is a joint project with Philips Healthcare offering possibilities for advanced endovascular research, device development and courses in endovascular treatment. The equipment is continuously upgraded and used in activities like:

  • Research in endovascular devices
  • Experimental stroke research, combined
  • Radiation reduction in angiography
  • Development of direct puncture devices
  • Superselective stem cell installation
  • Courses in endovascular stroke treatment



Michael Söderman

Telefon: 51774037
Enhet: Neuro Holmin
E-post: Michael.Soderman@ki.se


The microPET Focus 120 (Siemens, CTI) is a stand-alone rodent camera for performing dynamic (every second for minutes up to hours) studies of molecules labeled with positron-emitting nuclides. It has a high sensitivity, resolution of 1.3 mm, axial field-of-view 7.6 - 22 cm (CBM) and a removable bed for repositioning in other imaging modalities. It is used in (but not limited to) evaluations of:

  • Novel imaging molecules, from small
  • Longitudinal studies of normo- and
  • New biomarkers of disease processes
  • Novel administration routes
  • Efficacy of experimental vs. conventional


nanoScan PET-MRI/CT

The unit is equipped with a state-of-the-art Mediso nanoScan® PET-MRI/CT multimodal small animal imaging system, comprising a 1T static MRI modul (spatial resolution <100 µm), a pet modul (spatial resolution 0.8mm) and a ct modul (voxel size: 10-34 µm). < /p>

The unit can offer multimodal (PET, CT, MRI) quantitative imaging measurements on small animals for studies related to for example:

  • Radioligand development
  • Molecular imaging biomarker development
  • Drug development (microdosing, occupancy, etc.)
  • Various molecular imaging experiments in translational animal model


Senior lab manager

Miklós Tóth

E-post: Miklos.Toth@ki.se


The MRI platform has a 9.4 T Varian scanner with a 30 cm bore. It is a well equipped state-of-the-art system, which is ideal for characterizing different rat and mouse models for various diseases and translational research. We can offer support to research groups from academia and industry with different applications such as:

  • Anatomical imaging of brain and whole body (2 and 3-D)
  • Functional imaging (fMRI, pharmacological MRI and cardiac imaging)
  • Magnetic Resonance Spectroscopy (1H MRS)



Peter Damberg

Telefon: 08-517 765 13
E-post: peter.damberg@ki.se

Contact KERIC