Division of Transplantation Surgery

The Division of Transplantation Surgery aims to significantly improve quality of life for patients with various disorders, as well as giving new life to those where no other treatment is available.

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The most natural treatment

Health in man is dependent on well-functioning organs. Some organs may fail soon after birth, as in different inherited disorders, others later in life. When losing adequate function, this can be artificially corrected by, for instance, dialysis in end stage renal disease or insulin treatment in diabetes caused by insufficient pancreatic endocrine function. For some organs, such as the liver, no artificial replacement therapy is available and liver failure in an otherwise healthy person will end the life of this person.

Today, we know a great deal about the different functions of our various organs, but far from everything we need to know to be able to artificially replace those functions completely. Organ replacement and repair by transplantation compensates fully for the lost function, i.e. all functions including those yet not discovered, simply because those organs and cells know exactly what to do. Therefore, transplantation is the most natural treatment for a failing organ. Organs have developed over millions of years to possess the knowledge and functions necessary to maintain a good quality of life for the host.

Organisation

Please feel free to contact us!
 

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Gabriel Oniscu

Head of Division, Professor
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Bo Göran Ericzon

Professor, Senior
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Greg Nowak

Adjunct Professor

News and Calendar

Selected news

Calendar for the Division of Transplantation Surgery

Address

Karolinska Institutet
Department of Clinical Sciences, Intervention and Technology
Division of Transplantation Surgery
Karolinska University Hospital, Huddinge
SE-141 86 Stockholm

Publications

All publications from group members

Staff and contact

Head of Division

All members of the group

Research

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Gabriel Oniscu

Professor/Senior Physician

Gabriel has a particular clinical and research interest in novel organ perfusion and preservation technologies to improve transplant outcomes and has been one of the pioneers in the field in the UK. He is also using novel machine perfusion technologies as a platform for better organ assessment prior to transplantation and for the testing and delivery of organ repair therapies such as senolytic drugs or human biliary epithelial cells to induce organ repair and reconditioning. In collaboration with engineering teams his research also focused on the development of real-time non-invasive optical imaging technology to analise the biomolecular composition of liver tissue and bile.

Gabriel's second research interest is access to transplantation and transplant outcomes. He was one of the lead investigators in the NIHR funded study Access to Tranplantation and Transplant Outcome Measures (ATTOM) that explored socio-economic and health literacy factors in renal transplantation in the UK.

More organs for transplantation using gentler techniques

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Bo Göran Ericzon

Professor, Senior

Teaching areas
Organtransplantation. Liver cell transplantation.

Research areas
Liver transplantation. Ischemia-reperfusion studies with microdialysis technique. Domino liver transplantation and liver transplantation of familiar amyloidotic polyneuropathy (FAP). Combined liver- and stemcell transplantation of liver cancer. Liver cell transplantation.

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Erik Berglund

Affiliated to Research

Teaching areas
Current areas: Transplantation Immunology. Transplantation surgery. Biochemistry. Histology.
Previous areas: Physiology. Endocrinology. Anatomy. Basic research in cancer.

Research areas
Current areas: Transplantation tolerance, novel immunosuppression treatments in allo- and xenotransplantation, organ machine perfusion, ischemia-reperfusion injury.
Previous areas: Parathyroid pathology. Basic research in diabetes.

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Ewa Ellis

Affiliated to Research

Research areas
Isolation of Hepatocytes

Helena Maria Genberg

Affiliated to Research

Research areas
Bloodgroup incompatible organtransplantation

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Carl Jorns

Affiliated to Research

Teaching areas
Organ donation,donation after circulatory death, liver transplantation, cell transplantation, transplantation surgery, chirurgia minor, medical student mentoring.

Research areas
Carl Jorns’ research involves translational research in organ donation and transplantation as well as regenerative medicine. Current research projects include neonatal organ donation, experimental and clinical hepatocyte transplantation.

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Makiko Kumagai-Braesch

Affiliated to Research

Teaching areas
Immunology, immunosuppressive drugs, preclinical methods for pancreatic islet isolation characterization

Research areas
Tolerance induction by cell therapy in liver transplantation, preclinical research for pancreatic islet isolation and transplantation.

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Torbjörn Lundgren

Affiliated to Research

Research areas
Pancreas islet and organtransplantation

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Greg Nowak

Adjunct Professor

Research areas
Machine perfusion of liver graft

Lars Wennberg

Affiliated to Research

Teaching areas
Transplantation surgery orientation kidney transplantation. Pancreas transplantation and heart transplantation

Research areas
Kidney transplantation, transplantation immunology, ABO-incompatibility, organ preservation, ischemia-reperfusion, immunosuppression, immunological tolerance, transplantation immunized patients, kidney exchange programs, pediatric transplantation, heart transplantation, patient compliance, renal medicine, xenotransplantation.

Education

We participate in the education of medical students, semester 7, and arrange courses for basic surgical training with transplantation surgery profile, SVK, semester 11, twice per year.  This course contains practical surgical training in the large animal laboratory.