Carl Jorns

About me
Publications
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CV
Public outreach and news

About me

Carl studied medicine at Albert-Ludwigs-Universität Freiburg, Germany and
obtained a doctoral degree at the department of Virology with a thesis on
interferon stimulated genes. He received clinical surgical training in
general and transplantation surgery at Karolinska University Hospital. Carl
obtained his PhD at Karolinska Institutet in 2015 on clinical and
experimental hepatocyte transplantation. Carl is currently the head
of liver transplantation at the Department of Transplantation Surgery,
Karolinska University Hospital.

Research

Carl´s research involves translational research in organ donation and
transplantation as well as regenerative medicine. His research includes organ
donation from neonatal donors, clinical and experimental hepatocyte
transplantation.

Articles

Article: GUT. 2025;74(7):1125-1136
Unlocking novel T cell-based immunotherapy for hepatocellular carcinoma through neoantigen-driven T cell receptor isolation
Maravelia P; Yao H; Cai C; Silva DN; Fransson J; Nilsson OB; Lu Y-CW; Micke P; Botling J; Gatto F; Rovesti G; Carlsten M; Sallberg M; Stal P; Jorns C; Buggert M; Pasetto A
Article: CELL TRANSPLANTATION. 2025;34:9636897241303269
The Potential of Neonatal Organ Donation in Central Sweden
Bluhme E; Henckel E; Hallberg B; Jorns C
Article: LIVER INTERNATIONAL. 2025;45(1):e16214
Outcome of Liver Retransplantation in Patients With Primary Sclerosing Cholangitis
Molinaro A; Engesaeter LK; Jorns C; Nordin A; Rasmussen A; Line P-D; Pall V; Ericzon B-G; Bennet W; Hov JR; Melum E
Article: LIVER TRANSPLANTATION. 2024;30(11):1132-1144
Normothermic regional perfusion in controlled DCD liver procurement: Outcomes of the Swedish national implementation protocol
Bluhme E; Gaebel M; Martinez de la Maza L; Nilsen V; Hildebrand K; Jarsaeter J; Baath C; Proos M; Romano A; Villard C; Oniscu GC; Gustafsson N; Thompson M; Hansson C; Loefstedt M; Andersson Lindholm J; Falk L; Bennet W; Jorns C
Article: SCIENCE IMMUNOLOGY. 2024;9(99):eadn2362
MAIT cell heterogeneity across paired human tissues reveals specialization of distinct regulatory and enhanced effector profiles
Kammann T; Cai C; Sekine T; Mouchtaridi E; Boulouis C; Nilsen V; Ballesteros OR; Mueller TR; Gao Y; Raineri EJM; Mily A; Adamo S; Constantz C; Niessl J; Weigel W; Kokkinou E; Stamper C; Marchalot A; Bassett J; Ferreira S; Rodahl I; Wild N; Brownlie D; Tibbitt C; Mak JYW; Fairlie DP; Leeansyah E; Michaelsson J; Marquardt N; Mjosberg J; Jorns C; Buggert M; Sandberg JK
Article: BMJ OPEN. 2024;14(6):e081933
Incidence, management and outcomes in hepatic artery complications after paediatric liver transplantation: protocol of the retrospective, international, multicentre HEPATIC Registry
Li W; van der Doef HPJ; Wildhaber BE; Marra P; Bravi M; Pinelli D; Minetto J; Dip M; Sierre S; de Santibanes M; Ardiles V; Uno JW; Hardikar W; Bates S; Goh L; Aldrian D; Seisenbacher J; Vogel GF; Neto JS; da Fonseca EA; Costa CM; Ferreira CT; Nader LS; Farina MA; Dajani KZ; Parente A; Bigam DL; Liang T-B; Bai X; Zhang W; Gonsorcikova L; Fronek J; Bohus S; Franchi-Abella S; Gonzales E; Guerin F; Junge N; Baumann U; Richter N; Hartleif S; Sturm E; Rajakannu M; Palaniappan K; Rela M; Pawaria A; Rajakrishnan H; Surendran S; Kumar M; Agarwal S; Gupta S; Asthana S; Bandewar V; Raichurkar K; Spada M; Monti L; Alterio T; Yanagi Y; Uchida H; Komine R; Evans H; Carr-Boyd P; Duncan D; Stefanowicz M; Latka-Grot J; Kolesnik A; Broering DC; Raptis DA; Marquez KAH; Mali V; Aw M; Beretta M; Van der Schyff F; Quintero-Bernabeu J; Mercadal-Hally M; Larrarte K M; Andres AM; Hernandez-Oliveros F; Frauca E; Casswall T; Jorns C; Delle M; Gupte G; Sharif K; McGuirk S; Superina R; Caicedo JC; Jaramillo C; Bitterfeld L; Kastenberg Z; Shah AA; Domenick B; Acord MR; Mazariegos GV; Soltys K; DiNorcia J; Antala S; Florman SS; Buchholz BM; Herden U; Fischer L; Dierckx RAJO; Hartog H; Bokkers RPH
Journal article: EGASTROENTEROLOGY. 2024;2(1):e100045
Treatment of cholangiocarcinoma in patients with primary sclerosing cholangitis: a comprehensive review
Villard C; Jorns C; Bergquist A
Article: NATURE COMMUNICATIONS. 2024;15(1):1752
Intestinal stroma guides monocyte differentiation to macrophages through GM-CSF
Kvedaraite E; Lourda M; Mouratidou N; Duking T; Padhi A; Moll K; Czarnewski P; Sinha I; Xagoraris I; Kokkinou E; Damdimopoulos A; Weigel W; Hartwig O; Santos TE; Soini T; Van Acker A; Rahkonen N; Tullberg MF; Ringqvist E; Buggert M; Jorns C; Lindforss U; Nordenvall C; Stamper CT; Unnersjoe-Jess D; Akber M; Nadisauskaite R; Jansson J; Vandamme N; Sorini C; Grundeken ME; Rolandsdotter H; Rassidakis G; Villablanca EJ; Idestroem M; Eulitz S; Arnell H; Mjoesberg J; Henter J-I; Svensson M
Article: AMERICAN JOURNAL OF CASE REPORTS. 2023;24:e938678
Liver Transplantation for Liver Metastasis of a Pseudopapillary Pancreatic Neoplasm in a Male Patient
Granat RS; Romano A; Villard C; Lissing M; Joneberg J; Danielsson O; Moro CF; Jorns C
Journal article: CYTOTHERAPY. 2023;25(6):s237-s238
1053 Immunotherapy: IDENTIFICATION OF IMMUNOGENIC SIGNATURES IN HEPATOCELLULAR CARCINOMA GUIDES T CELLS AGAINST RELEVANT TARGETS FOR SUCCESSFUL IMMUNOTHERAPY
Maravelia P; Lu Y; Cai C; Nilsson O; Gatto F; Rovesti G; Silva DN; Sallberg M; Jorns C; Buggert M; Pasetto A
Article: EJSO. 2022;48(12):2432-2439
Prediction of survival in patients with colorectal liver metastases-development and validation of a prognostic score model
Villard C; Abdelrafee A; Habib M; Ndegwa N; Jorns C; Sparrelid E; Allard M-A
Article: TRIALS. 2022;23(1):831
SOULMATE: the Swedish study of liver transplantation for isolated colorectal cancer liver metastases not suitable for operation or ablation, compared to best established treatment-a randomized controlled multicenter trial
Reivell V; Hagman H; Haux J; Jorns C; Lindner P; Taflin H
Article: EJSO. 2022;48(7):1656-1663
Prognostic impact of inter-metastatic heterogeneity of viable tumour cells in colorectal liver metastases
Stromberg C; de la Maza LM; Moro CF; Gerling M; Jorns C; Sparrelid E; Lohr MJ; Villard C
Article: HPB. 2022;24(7):1138-1144
Liver transplantation in patients with post-hepatectomy liver failure - A Northern European multicenter cohort study
Sparrelid E; Thorsen T; Sauter C; Jorns C; Stal P; Nordin A; de Boer MT; Buis C; Yaqub S; Schultz NA; Larsen PN; Sallinen V; Line P-D; Gilg S
Journal article: HPB. 2022;24:s167-s168
Liver Transplantation in Patients with Post-Hepatectomy Liver Failure – A Northern European Multicenter Cohort Study
Sparrelid E; Thorsen T; Sauter C; Jorns C; Stål P; Nordin A; de Boer M; Buis C; Yaqub S; Schultz NA; Larsen PN; Sallinen V; Line P-D; Gilg S
Journal article: HPB. 2022;24:s96-s97
The Prognostic Impact of Viable Tumour Cells in Patients with Colorectal Liver Metastases
Strömberg C; de la Maza LM; Jorns C; Sparrelid E; Löhr M; Villard C
Article: CELL TRANSPLANTATION. 2022;31:9636897211069900
Procurement and Evaluation of Hepatocytes for Transplantation From Neonatal Donors After Circulatory Death
Bluhme E; Henckel E; Gramignoli R; Kjellin T; Hammarstedt C; Nowak G; Karadagi A; Johansson H; Jynge O; Soderstrom M; Fischler B; Strom S; Ellis E; Hallberg B; Jorns C
Article: FRONTIERS IN IMMUNOLOGY. 2021;12:752104
CD5 Surface Expression Marks Intravascular Human Innate Lymphoid Cells That Have a Distinct Ontogeny and Migrate to the Lung
Alisjahbana A; Gao Y; Sleiers N; Evren E; Brownlie D; von Kries A; Jorns C; Marquardt N; Michaelsson J; Willinger T
Article: GUT. 2021;70(10):1914-1924
COVID-19 in liver transplant candidates: pretransplant and post-transplant outcomes - an ELITA/ELTR multicentre cohort study
Belli LS; Duvoux C; Cortesi PA; Facchetti R; Iacob S; Perricone G; Radenne S; Conti S; Patrono D; Berlakovich G; Hann A; Pasulo L; Castells L; Faitot F; Detry O; Invernizzi F; Magini G; De Simone P; Kounis I; Morelli MC; Diaz Fontenla F; Ericzon B-G; Loinaz C; Johnston C; Gheorghe L; Lesurtel M; Romagnoli R; Kollmann D; Perera MTPR; Fagiuoli S; Mirza D; Coilly A; Toso C; Zieniewicz K; Elkrief L; Karam V; Adam R; den Hoed C; Merli M; Puoti M; De Carlis L; Oniscu GC; Piano S; Angeli P; Fondevila C; Polak WG
Article: PEDIATRIC TRANSPLANTATION. 2021;25(6):e13993
Comparison of cystatin C, creatinine, and iohexol clearance in pediatric liver transplantation-a retrospective cohort study
Bluhme E; Malenicka S; Fischler B; Nemeth A; Berg UB; Jorns C
Article: CHILDREN-BASEL. 2021;8(9):760
ABO Incompatible Liver Transplantation in Children: A 20 Year Experience from Centres in the TransplantChild European Reference Network
Markiewicz-Kijewska M; Kalicinski P; Torres Canizales J; Di Giorgio A; Baumann U; Jorns C; Baker A; Lopes MF; Frauca Remacha E; Lopez-Granados E; Jara Vega P; Basso M-S; Kowalewski G; Kaminska D; Ferreira S; Liccardo D; Pietrobattista A; Spada M
Article: HEPATOBILIARY SURGERY AND NUTRITION. 2021;10(4):476-485
The potential use of extended criteria donors and eligible recipients in liver transplantation for unresectable colorectal liver metastases in Central Sweden
Villard C; Westman J; Frank J; Jynge O; Sparrelid E; Jorns C
Article: EJSO. 2021;47(8):2038-2045
Conversion therapy in patients with colorectal liver metastases
Villard C; Habib M; Nordenvall C; Nilsson PJ; Jorns C; Sparrelid E
Article: SCIENCE ADVANCES. 2021;7(30):eabg5733
Disorganization and degeneration of liver sympathetic innervations in nonalcoholic fatty liver disease revealed by 3D imaging
Adori C; Daraio T; Kuiper R; Barde S; Horvathova L; Yoshitake T; Ihnatko R; Valladolid-Acebes I; Vercruysse P; Wellendorf AM; Gramignoli R; Bozoky B; Kehr J; Theodorsson E; Cancelas JA; Mravec B; Jorns C; Ellis E; Mulder J; Uhlen M; Bark C; Hokfelt T
Article: MOLECULAR THERAPY. 2021;29(5):1903-1917
Correction of a urea cycle defect after ex vivo gene editing of human hepatocytes
Zabulica M; Srinivasan RC; Akcakaya P; Allegri G; Bestas B; Firth M; Hammarstedt C; Jakobsson T; Jakobsson T; Ellis E; Jorns C; Makris G; Scherer T; Rimann N; van Zuydam NR; Gramignoli R; Forslow A; Engberg S; Maresca M; Rooyackers O; Thony B; Haberle J; Rosen B; Strom SC
Article: FRONTIERS IN ENDOCRINOLOGY. 2021;11:554922
Chenodeoxycholic Acid Modulates Bile Acid Synthesis Independent of Fibroblast Growth Factor 19 in Primary Human Hepatocytes
Johansson H; Sondergaard JN; Jorns C; Kutter C; Ellis ECS
Article: SCIENTIFIC REPORTS. 2020;10(1):7052
Systemic modified messenger RNA for replacement therapy in alpha 1-antitrypsin deficiency
Karadagi A; Cavedon AG; Zemack H; Nowak G; Eybye ME; Zhu X; Guadagnin E; White RA; Rice LM; Frassetto AL; Strom S; Jorns C; Martini PGV; Ellis E
Article: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2020;198:105558
Lipidomic analysis of human primary hepatocytes following LXR activation with GW3965 identifies AGXT2L1 as a main target associated to changes in phosphatidylethanolamine
Santinha D; Klopot A; Marques I; Ellis E; Jorns C; Johansson H; Melo T; Antonson P; Jakobsson T; Felix V; Gustafsson J-A; Domingues MR; Mode A; Helguero LA
Article: JOURNAL OF CLINICAL AND EXPERIMENTAL HEPATOLOGY. 2020;10(2):106-113
Blood Group Antigen Expression in Isolated Human Liver Cells in Preparation for Implementing Clinical ABO-Incompatible Hepatocyte Transplantation
Tokodai K; Kumagai-Braesch M; Karadagi A; Johansson H; Agren N; Jorns C; Ericzon B-G; Ellis E
Article: TRANSPLANTATION. 2020;104(3):522-525
First European Case of Simultaneous Liver and Pancreas Transplantation as Treatment of Wolcott-Rallison Syndrome in a Small Child
Nordstrom J; Lundgren M; Jorns C; Fischler B; Arnell H; Dlugosz R; Sandberg J; Wennberg L; Nowak G
Article: TRANSPLANTATION. 2019;103(3):630-637
Open Randomized Multicenter Study to Evaluate Safety and Efficacy of Low Molecular Weight Sulfated Dextran in Islet Transplantation
von Zur-Muhlen B; Lundgren T; Bayman L; Berne C; Bridges N; Eggerman T; Foss A; Goldstein J; Jenssen T; Jorns C; Morrison Y; Ryden M; Schwieger T; Tufveson G; Nilsson B; Korsgren O
Article: CELL TRANSPLANTATION. 2018;27(11):1692-1704
Ex Vivo Generation of Donor Antigen-Specific Immunomodulatory Cells A Comparison Study of Anti-CD80/86 mAbs and CTLA4-lg Costimulatory Blockade
Watanabe M; Kumagai-Braesch M; Yao M; Thunberg S; Berglund D; Sellberg F; Jorns C; Enoksson SL; Henriksson J; Lundgren T; Uhlin M; Berglund E; Ericzon B-G
Article: JOURNAL OF CLINICAL AND EXPERIMENTAL HEPATOLOGY. 2018;8(2):162-168
Circulating Fibroblast Growth Factor 19 in Portal and Systemic Blood
Johansson H; Mork L-M; Li M; Sandblom AL; Bjorkhem I; Hoijer J; Ericzon B-G; Jorns C; Gilg S; Sparrelid E; Isaksson B; Nowak G; Ellis E
Article: ONCOTARGET. 2017;8(36):60257-60269
Characterization of infiltrating lymphocytes in human benign and malignant prostate tissue
Radestad E; Egevad L; Jorns C; Mattsson J; Sundberg B; Nava S; Ericzon B-G; Henningsohn L; Levitsky V; Uhlin M
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2017;47(8):1280-1294
Composition and functionality of the intrahepatic innate lymphoid cell-compartment in human nonfibrotic and fibrotic livers
Forkel M; Berglin L; Kekalainen E; Carlsson A; Svedin E; Michaelsson J; Nagasawa M; Erjefalt JS; Mori M; Flodstrom-Tullberg M; Bergquist A; Ljunggren H-G; Westgren M; Lindforss U; Friberg D; Jorns C; Ellis E; Bjorkstrom NK; Mjosberg J
Article: PLOS ONE. 2017;12(5):e0177279
Exogenous alpha 1-antitrypsin down-regulates SERPINA1 expression
Karadagi A; Johansson H; Zemack H; Salipalli S; Mork L-M; Kannisto K; Jorns C; Gramignoli R; Strom S; Stokkeland K; Ericzon B-G; Jonigk D; Janciauskiene S; Nowak G; Ellis ECS
Article: MATURITAS. 2017;96:39-44
Differential expression of sex hormone receptors in abdominal aortic aneurysms
Villard C; Eriksson P; Kronqvist M; Lengquist M; Jorns C; Hartman J; Roy J; Hultgren R
Article: PLOS ONE. 2016;11(9):e0161383
Maintenance of Hepatic Functions in Primary Human Hepatocytes Cultured on Xeno-Free and Chemical Defined Human Recombinant Laminins
Watanabe M; Zemack H; Johansson H; Hagbard L; Jorns C; Li M; Ellis E
Journal article: GASTROENTEROLOGY. 2016;150(4):s1036
FGF19 and Bile Acids in Portal and Systemic Serum
Johansson H; Mork L-M; Li M; Zemack H; Sandblom AL; Hoijer J; Jorns C; Gilg S; Sparrelid E; Ericzon B-G; Isaksson B; Nowak G; Ellis E
Article: AMERICAN JOURNAL OF TRANSPLANTATION. 2016;16(3):1021-1030
De Novo Donor-Specific HLA Antibody Formation in Two Patients With Crigler-Najjar Syndrome Type I Following Human Hepatocyte Transplantation With Partial Hepatectomy Preconditioning
Jorns C; Nowak G; Nemeth A; Zemack H; Mork L-M; Johansson H; Gramignoli R; Watanabe M; Karadagi A; Alheim M; Hauzenberger D; van Dijk R; Bosma PJ; Ebbesen F; Szakos A; Fischler B; Strom S; Ellis E; Ericzon B-G
Article: PLOS ONE. 2014;9(8):e105375
In Situ Characterization of Intrahepatic Non-Parenchymal Cells in PSC Reveals Phenotypic Patterns Associated with Disease Severity
Berglin L; Bergquist A; Johansson H; Glaumann H; Jorns C; Lunemann S; Wedemeyer H; Ellis EC; Bjorkstrom NK
Article: CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING. 2014;34(2):109-113
Membrane cut-off does not influence results regarding the measurement of small molecules - a comparative study between 20-and 100-kDa catheters in hepatic microdialysis
D'souza MA; Ravn A; Jorns C; Nowak G; Isaksson B
Article: CELL TRANSPLANTATION. 2014;23(8):1009-1018
Strategies for Short-Term Storage of Hepatocytes for Repeated Clinical Infusions
Jorns C; Gramignoli R; Saliem M; Zemack H; Mork L-M; Isaksson B; Nowak G; Ericzon B-G; Strom S; Ellis E
Article: CELL TRANSPLANTATION. 2014;23(9):1143-1151
Hypothermic Storage of Human Hepatocytes for Transplantation
Gramignoli R; Dorko K; Tahan V; Skvorak KJ; Ellis E; Jorns C; Ericzon B-G; Fox IJ; Strom SC
Article: LIPIDS. 2014;49(1):71-83
LXR Driven Induction of HDL-Cholesterol is Independent of Intestinal Cholesterol Absorption and ABCA1 Protein Expression
Kannisto K; Gafvels M; Jiang Z-Y; Slatis K; Hu X; Jorns C; Steffensen KR; Eggertsen G
Article: PLOS ONE. 2013;8(11):e78550
Mice with Chimeric Livers Are an Improved Model for Human Lipoprotein Metabolism
Ellis ECS; Nauglers S; Parini P; Mork L-M; Jorns C; Zemack H; Sandblom AL; Bjorkhem I; Ericzon B-G; Wilson EM; Strom SC; Grompe M
Article: STEM CELL RESEARCH. 2013;11(1):563-573
New potential cell source for hepatocyte transplantation: Discarded livers from metabolic disease liver transplants
Gramignoli R; Tahan V; Dorko K; Skvorak KJ; Hansel MC; Zhao W; Venkataramanan R; Ellis ECS; Jorns C; Ericzon B-G; Rosenborg S; Kuiper R; Soltys KA; Mazariegos GV; Fox IJ; Wilson EM; Grompe M; Strom SC
Article: JOURNAL OF SURGICAL RESEARCH. 2012;178(2):959-967
Oxygen-charged HTK-F6H8 emulsion reduces ischemia-reperfusion injury in kidneys from brain-dead pigs
Asif S; Sedigh A; Nordstrom J; Brandhorst H; Jorns C; Lorant T; Larsson E; Magnusson PU; Nowak G; Theisinger S; Hoeger S; Wennberg L; Korsgren O; Brandhorst D
Article: WORLD JOURNAL OF HEPATOLOGY. 2012;4(5):176-183
Improved cryopreservation of human hepatocytes using a new xeno free cryoprotectant solution
Saliem M; Holm F; Tengzelius RB; Jorns C; Nilsson L-M; Ericzon B-G; Ellis E; Hovatta O
Article: CELL TRANSPLANTATION. 2009;18(2):183-193
Generation of Hepatocyte-Like Cells From In Vitro Transdifferentiated Human Fetal Pancreas
Sumitran-Holgersson S; Nowak G; Thowfeequ S; Begum S; Joshi M; Jaksch M; Kjaeldgaard A; Jorns C; Ericzon B-G; Tosh D
Article: LIVER TRANSPLANTATION. 2008;14(12):1793-1802
Evidence for No Relevance of Anti-Major Histocompatibility Complex Class I-Related Chain A Antibodies in Liver Transplantation
Uzunel M; Kasimu H; Joshi M; Ge X; Liu J; Xu B; Jaksch M; Jorns C; Nowak G; Sumitran-Holgersson S
Article: JOURNAL OF IMMUNOLOGY. 2008;181(6):4219-4228
Elevated numbers of FcγRIIIA⁺ (CD16⁺) effector CD8 T cells with NK cell-like function in chronic hepatitis C virus infection
Bjorkstrom NK; Gonzalez VD; Malmberg K-J; Falconer K; Alaeus A; Nowak G; Jorns C; Ericzon B-G; Weiland O; Sandberg JK; Ljunggren H-G
Article: JOURNAL OF VIROLOGY. 2007;81(14):7776-7785
Induction of MxA gene expression by influenza A virus requires type I or type III interferon signaling
Holzinger D; Jorns C; Stertz S; Boisson-Dupuis S; Thimme R; Weidmann M; Casanova J-L; Haller O; Kochs G
Article: CARDIOVASCULAR ULTRASOUND. 2007;5:10
Doppler findings in a rare coronary artery fistula.
Jung C; Jorns C; Huhta J
Article: JOURNAL OF MEDICAL VIROLOGY. 2006;78(1):74-82
Rapid and simple detection of IFN-neutralizing antibodies in chronic hepatitis C non-responsive to IFN-α
Jorns C; Holzinger D; Thimme R; Spangenberg HC; Weidmann M; Rasenack J; Blum HE; Haller O; Kochs G
Journal article: HEPATOLOGY. 2003;38:322
337 MXA gene expression as a sensitive marker for IFN bioactivity and neutralizing antibodies in chronic hepatitis C virus infection
Jorns C; Thimme R; Spangenberg H-C; Kersting N; Rasenack J; Weidmann M; Blum HE; Haller O; Kochs G
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All other publications

Letter: LIVER TRANSPLANTATION. 2025;31(3):e14
Reply: Does the utilization of machine perfusion require a boundary for livers donated after circulatory death?
Bluhme E; Jorns C
Review: EGASTROENTEROLOGY. 2024;2(1):e100045
Treatment of cholangiocarcinoma in patients with primary sclerosing cholangitis: a comprehensive review.
Villard C; Jorns C; Bergquist A
Conference publication: CYTOTHERAPY. 2023;25(6):S237-S238
IDENTIFICATION OF IMMUNOGENIC SIGNATURES IN HEPATOCELLULAR CARCINOMA GUIDES T CELLS AGAINST RELEVANT TARGETS FOR SUCCESSFUL IMMUNOTHERAPY
Maravelia P; Lu Y; Cai C; Nilsson O; Gatto F; Rovesti G; Silva DN; Sallberg M; Jorns C; Buggert M; Pasetto A
Review: PEDIATRIC TRANSPLANTATION. 2023;27(3):e14486
Potential of neonatal organ donation and outcome after transplantation
Bluhme E; Henckel E; Jorns C
Conference publication: TRANSPLANTATION. 2022;106(8S):185
Liver transplantation for liver metastasis of pseudopapillary pancreatic neoplasm in a male patient
Granat RS; Romano A; Jorns C
Conference publication: TRANSPLANT INTERNATIONAL. 2021;34:169
QUALITY OF LIFE AFTER LIVER TRANSPLANTATION, A CROSS-SECTIONAL SINGLE CENTRE STUDY
Vidgren M; Jorns C; Lindstrom L
Conference publication: TRANSPLANT INTERNATIONAL. 2021;34:87
COMPARISON OF CYSTATIN C, CREATININE AND IOHEXOL CLEARANCE IN PEDIATRIC LIVER TRANSPLANTATION - A RETROSPECTIVE COHORT STUDY
Bluhme E; Malenicka S; Fischler B; Nemeth A; Berg U; Jorns C
Conference publication: TRANSPLANT INTERNATIONAL. 2021;34:85
MANAGEMENT OF CONGENITAL PORTOSYSTEMIC SHUNTS
de la Maza LM; Casswall T; Magnusson M; Fischler B; Sund M; Dlugosz R; Jorns C; Delle M
Conference publication: EUROPEAN JOURNAL OF IMMUNOLOGY. 2021;51:170
Human CD5+innate lymphoid cells are intravascular precursors that migrate into the lung
Alisjahbana A; Gao Y; Sleiers N; Evren E; Brownlie D; Von Kries A; Jorns C; Michaelsson J; Marquardt N; Willinger T
Conference publication: CYTOTHERAPY. 2021;23(5):S90
IDENTIFICATION OF TARGETS FOR TCR-IMMUNOTHERAPY IN HEPATOCELLULAR CARCINOMA USING A CLINICALLY RELEVANT PLATFORM
Maravelia P; Potti AP; Silva DN; Healy K; Sekine T; Chrobok M; Jorns C; Sallberg M; Buggert M; Pasetto A
Conference publication: ANNALS OF ONCOLOGY. 2020;31:S1426
Methodology for identification of clinically relevant targets for TCR-immunotherapy in hepatocellular carcinoma
Maravelia P; Potti AP; Sekine T; Silva DSN; Healy K; Chrobok M; Jorns C; Sallberg M; Buggert M; Pasetto A
Conference publication: TRANSPLANT INTERNATIONAL. 2019;32:200
THE POTENTIAL OF NEONATAL DCD ORGAN DONATION IN SWEDEN - A POPULATION BASED STUDY
Bluhme E; Hallberg B; Jorns C
Conference publication: TRANSPLANT INTERNATIONAL. 2019;32:191
LIVER TRANSPLANTATION FOR IRRESECTABLE COLORECTAL LIVER METASTASIS: A RETROSPECTIVE ANALYSIS OF POTENTIAL RECIPIENT AS WELL AS POTENTIAL EXTENDED CRITERIA DONORS
Sparrelid E; Westman J; Frank J; Jorns C
Meeting abstract: TRANSPLANTATION. 2019;103(9):S5
Human Hepatocyte Spheroids Show Plasticity-enabling Extended Culture and Pretransplant Conditioning
Karadagi A; Jorns C; Ericzon B-G; Nowak G; Chotteau V; Ellis ECS
Book chapter: PRINCIPLES OF REGENERATIVE MEDICINE. 2019;p. 229-246
Chapter 16 Cell Therapy of Liver Disease From Hepatocytes to Stem Cells
Strom SC; Jorns C
Conference publication: HEPATOLOGY. 2018;68:124A
Graft Derived Cell-Free DNA As a Non-Invasive Biomarker to Track Early Rejection of Transplanted Primary Human Hepatocytes
Lee C; Dhawan A; Mitry RR; Folarin N; Lea N; Jorns C; Ellis E; Gramignoli R; Strom SC; Fitzpatrick E
Meeting abstract: TRANSPLANTATION. 2018;102:S233
Effect of the Isolation Procedure and Inflammatory Cytokines on Blood Group Antigen Expression on Human Hepatocytes in Preparation for Investigating ABO-Incompatible Hepatocyte Transplantation
Tokodai K; Kumagai-Braesch M; Karadagi A; Johansson H; Jorns C; Ericzon B-G; Ellis E
Meeting abstract: TRANSPLANTATION. 2018;102:S1-S2
Evaluation of Enhanced Recovery Program in Liver Transplanted Patients: Can We Beat the Benchmarks in Liver Transplantation?
Wang B; Romano A; Kjaernet F; Jorns C; Soderdahl G; Ericzon B-G; Nowak G
Conference publication: TRANSPLANTATION. 2018;102:155
Enhanced recovery program: an effective tool for post-operative care of liver transplanted patients
Romano A; Wang B; Kjaernet F; Gjertsen H; Dlugosz R; Jorns C; Soderdahl G; Ericzon B-G; Nowak G
Conference publication: TRANSPLANT INTERNATIONAL. 2017;30:332
SIMULTANEOUS PEDIATRIC LIVER AND PANCREAS TRANSPLANTATION IN A PATIENT WITH WOLCOTT-RALLISON SYNDROME
Nordstroem J; Jorns C; Dlugosz R; Wennberg L; Nowak G
Conference publication: EUROPEAN JOURNAL OF IMMUNOLOGY. 2016;46:125
Ex vivo generation of alloantigen-specific T regulatory cells using selective T-cell costimulation blockade
Watanabe M; Kumagai-Braesch M; Thunberg S; Henrikson J; Sellberg F; Lundgren T; Yao MH; Jorns C; Berglund D; Berglund E; Ericzon B-G
Conference publication: TRANSPLANTATION. 2016;100(7):S15
En bloc dual kidney-pancreas transplantation into an adult recipient utilizing very small pediatric donor: No conflict with liver transplantation concerning anatomical division in respect to dividing arteries - all organs can be used
Nordstrom J; Jorns C; Sandberg J; Wennberg L
Conference publication: TRANSPLANTATION. 2016;100(7):S861
Comparison of three transplantation techniques in a mouse model of hepatocyte transplantation
Jorns C; Watanabe M; Kannisto K; Wiklander O; Zemack H; Strom S; Ericzon B-G; Ellis E
Conference publication: TRANSPLANTATION. 2015;99(11):S47
EX VIVO GENERATION OF ALLOANTIGEN-SPECIFIC T REGULATORY CELLS USING SELECTIVE T-CELL CO-STIMULATION BLOCKADE.
Watanabe M; Kumagai-Braesch M; Yao M; Berglund D; Jorns C; Thunberg S; Lind-Enoksson S; Henrikson J; Lundgren T; Sellberg F; Berglund E; Ericzon B-G
Conference publication: TRANSPLANT INTERNATIONAL. 2015;28:219
EX-VIVO GENERATION OF ALLOANTIGEN-SPECIFIC REGULATORY T CELLS USING SELECTIVE T-CELL COSTIMULATION BLOCKADE: A COMPARISON STUDY BETWEEN ANTI-CD80/86 MABS AND CTLA4-IG
Watanabe M; Kumagai-Braesch M; Berglund D; Thunberg S; Jorns C; Henriksson J; Lundgren T; Sellberg F; Berglund E; Ericzon B-G
Conference publication: TRANSPLANTATION. 2015;99(11):S252-S253
THE EFFICACY OF SPHEROIDAL HEPATOCYTE ON HEPATOCYTE TRANSPLANTATION
Watanabe M; Moro S; Jorns C; Mork L-M; Ingelman-Sundberg M; Ellis E
Conference publication: TRANSPLANTATION. 2015;99(11):S219
HEPATOCYTE TRANSPLANTATION NORMALIZES HYPERCHOLESTEROLEMIA AND AORTIC ACCUMULATION OF CHOLESTEROL IN APOLIPOPROTEIN E KNOCKOUT MICE.
Jorns C; Watanabe M; Mork L-M; Larsson L; Zemack H; Kuiper R; Strom S; Ericzon B-G; Parini P; Ellis E
Conference publication: TRANSPLANTATION. 2015;99(11):S71
GMP ISOLATION AND QUALITY ASSESMENT ON HUMAN AMNION EPITHELIAL CELL FOR CLINICAL THERAPIES.
Gramignoli R; Kannisto K; Srinivasan RC; Jorns C; Strom SC
Conference publication: XENOTRANSPLANTATION. 2015;22:S154
The efficacy of spheroidal hepatocyte on hepatocyte transplantation
Watanabe M; Moro S; Jorns C; Mork L-M; Ingelman-Sundberg M; Ellis E
Conference publication: XENOTRANSPLANTATION. 2015;22:S131
Hepatocyte transplantation normalizes hypercholesterolemia and aortic accumulation of cholesterol in apolipoprotein E knockout mice
Jorns C; Watanabe M; Mork L-M; Larsson L; Zemack H; Kuiper R; Strom S; Ericzon B-G; Parini P; Ellis E
Conference publication: XENOTRANSPLANTATION. 2015;22:S44
GMP isolation and quality assesment on human amnion epithelial cell for clinical therapies
Gramignoli R; Kannisto K; Srinivasan RC; Jorns C; Strom SC
Doctoral thesis: 2015
Hepatocyte transplantation : experimental and clinical studies
Jorns C
Corrigendum: PLOS ONE. 2014;9(7):e103870
Mice with Chimeric Livers Are an Improved Model for Human Lipoprotein Metabolism (vol 8, e78550, 2013)
Ellis ECS; Naugler WE; Parini P; Moerk L-M; Jorns C
Conference publication: TRANSPLANTATION. 2014;98:299
Antibody Mediated Rejection After Hepatocyte Transplantation Combined With Partial Hepatectomy in One of Two Patients With Crigler-Najjar Type
Jorns IC; Nemeth A; Nowak G; Zemack H; Mork L; Johansson H; Gramignoli R; Fischler B; Strom S; Ellis E; Ericzon B
Conference publication: AMERICAN JOURNAL OF TRANSPLANTATION. 2014;14:299
Antibody Mediated Rejection After Hepatocyte Transplantation Combined With Partial Hepatectomy in One of Two Patients With Crigler-Najjar Type
Jorns C; Nemeth A; Nowak G; Zemack H; Mork L; Johansson H; Gramignoli R; Fischler B; Strom S; Ellis E; Ericzon B
Meeting abstract: JOURNAL OF HEPATOLOGY. 2014;60(1):S104
EFFECT OF PURIFIED ALPHA 1-ANTITRYPSIN (AAT) ON EXPRESSION OF AAT IN NORMAL (PIMM) AND AAT DEFICIENT (PIZZ) PRIMARY HUMAN HEPATOCYTES
Ellis ECS; Johansson H; Zemack H; Jorns C; Gramignoli R; Strom S; Nowak G; Ericzon B-G
Conference publication: TRANSPLANT INTERNATIONAL. 2013;26:118
IMPROVED SHORT TERM COLD STORAGE OF HUMAN HEPATOCYTES FOR TRANSPLANTATION
Jorns C; Gramignoli R; Saliem M; Zemack H; Mork L-M; Isaksson B; Nowak G; Ericzon B-G; Strom S; Ellis E
Conference publication: HEPATOLOGY. 2013;58:799A
In Situ Characterization of the Intrahepatic Non-Parenchymal Cellular Compartment in PSC-Patients
Berglin L; Bergquist A; Glaumann H; Jorns C; Ellis ECS; Bjorkstrom NK
Conference publication: HEPATOLOGY. 2013;58:370A
Hepatocyte transplantation combined with partial liver resection preconditioning in patients with Crigler-Najjar type I
Jorns C; Nemeth A; Nowak G; Zemack H; Mork L-M; Johansson H; Gramignoli R; Fischler B; Strom S; Ellis ECS; Ericzon B-G
Published conference paper: TRANSPLANTATION PROCEEDINGS. 2013;45(5):1780-1786
Serum Apolipoprotein E as a Marker to Monitor Graft Function After Hepatocyte Transplantation in a Clinically Relevant Mouse Model
Jorns C; Takahashi T; Callaghan E; Zemack H; Larsson L; Nowak G; Parini P; Ericzon B-G; Ellis E
Conference publication: TRANSPLANTATION. 2012;94(10):216
Serum Apoe as a Reliable Marker to Monitor Graft Function after Hepatocyte Transplantation
Jorns C; Callaghan E; Takahashi T; Zemack H; Nilsson L-M; Nowak G; Parini P; Ericzon B-G; Ellis EC
Meeting abstract: TRANSPLANTATION. 2012;94(10):1006
Rapid Assessment of Viability and Function of Human Hepatocytes for Possible Transplantation
Gramignoli R; Dorko K; Tahan V; Skvorak KJ; Geller D; Fox IJ; Jorns C; Ericzon B-G; Ellis EC; Strom SC
Meeting abstract: TRANSPLANTATION. 2012;94(10):1005
Evaluation of Hepatocytes from Explanted-Diseased Livers for Transplantation
Gramignoli R; Tahan V; Dorko K; Skvorak KJ; Hansel MC; Mazariegos G; Soltys K; Fox IJ; Jorns C; Ericzon B-G; Ellis EC; Strom SC
Meeting abstract: TRANSPLANTATION. 2012;94(10):215
Rapid Assessment of Viability and Function of Human Hepatocytes for Possible Transplantation
Gramignoli R; Dorko K; Tahan V; Skvorak KJ; Geller D; Fox IJ; Jorns C; Ericzon B-G; Ellis EC; Strom SC
Meeting abstract: TRANSPLANTATION. 2012;94(10):214
Evaluation of Hepatocytes from Explanted-Diseased Livers for Transplantation
Gramignoli R; Tahan V; Dorko K; Skvorak KJ; Hansel MC; Mazariegos G; Soltys K; Fox IJ; Jorns C; Ericzon B-G; Ellis EC; Strom SC
Conference publication: TRANSPLANTATION. 2012;94(10):1006
Serum Apoe as a Reliable Marker to Monitor Graft Function after Hepatocyte Transplantation
Jorns C; Callaghan E; Takahashi T; Zemack H; Nilsson L-M; Nowak G; Parini P; Ericzon B-G; Ellis EC
Review: JOURNAL OF INTERNAL MEDICINE. 2012;272(3):201-223
Hepatocyte transplantation for inherited metabolic diseases of the liver
Jorns C; Ellis EC; Nowak G; Fischler B; Nemeth A; Strom SC; Ericzon BG
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2008;68(2):238-239
Elevated numbers of FcγRIIIA+ (CD16⁺) effector CD8 T-cells with NK cell-like function in chronic HCV infection
Bjorkstrom N; Gonzalez V; Malmberg K-J; Falconer K; Alaeus A; Nowak G; Jorns C; Ericzon B-G; Weiland O; Sandberg J; Ljunggren H-G
Published conference paper: SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES. 2008;22(4):938-942
Microdialysis monitoring for evaluation of the influence exerted by pneumoperitoneum on the kidney: an experimental study
Iwata T; Gilispie A; Jorns C; Yamamoto S; Nowak G; Ericzon B-G
Conference publication: XENOTRANSPLANTATION. 2007;14(5):437
In Vitro expanded human fetal pancreatic cells differentiate into hepatocytes and cholangiocytes upon treatment with dexamethasone and functionally engraft the liver in a model of toxin-induced liver damage
Jorns C; Nowak G; Thowfeequ S; Begum S; Ericzon B-G; Tosh D; Sumitran-Holgersson S
Conference publication: HEPATOLOGY. 2003;38(4):322A
MxA gene expression as a sensitive marker for IFN bioactivity and neutralizing antibodies in chronic hepatitis C virus infection.
Jorns C; Thimme R; Kersting N; Rasenack J; Weidmann M; Blum HE; Haller O; Kochs G
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Grants

Design of neoantigen-based vaccines against liver cancer
Swedish Research Council
1 January 2023 - 31 December 2025
Cell-based immunotherapy in solid organ transplantation to minimize systemic immunosuppression
Swedish Research Council
1 January 2019 - 31 December 2021

Employments

Affiliated to Research, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, 2025-2028

Degrees and Education

Docent, Karolinska Institutet, 2022
Degree Of Doctor Of Philosophy, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, 2015

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