Prevention, Intervention and Mechanisms in Public Health (PRIME Health) – Cecilia Magnusson's research group

The PRIME Health research group is a multidisciplinary team dedicated to addressing threats to population health and health equity. Our research broadly spans the interrelated areas of climate extremes, physical inactivity and cardiometabolic risk factors, and maternal and child health.

Illustration of health

Our network

PRIME Health maintains a close collaboration with the Centre for Epidemiology and Community Medicine (CES) in Region Stockholm, as well as the recently established Swedish Center for Impacts of Climate Extremes. Our international network encompasses scholars from various countries, including the United States, the United Kingdom, and Spain.

Our methods

We use a range of methods and data sources to forge interdisciplinary approaches to public health research. PRIME hosts the total population record-linkage “The Developmental Origins of Health and Disease-study” and are lead investigators of cohorts run by CES: The Stockholm Public Health CohortThe Stockholm Diabetes Preventive Program, the Increasing Children's Physical Activity by Policy, along with The Health Meter.

Our Projects

Climate Extremes:

We investigate vulnerability and adaptation to climate extremes to inform sustainable transformation and future scenarios. This encompasses analyzing a broad spectrum of climate extremes, including temperature fluctuations, floods, droughts, and storms. We utilize individual and aggregated level data at the national level from multiple countries and employ interdisciplinary approaches such as storylines and system dynamics models.

Funding: Formas, Forte, VR

Physical Activity, Obesity, and Cardiometabolic Diseases:

Following precision public health principles, we utilize biological samples and accelerometers alongside survey and health data registers for research within this domain. Our work includes observational and experimental studies examining the impact of outdoor school environments, risk stratification for cardiometabolic diseases, and the effectiveness of healthcare interventions.

Funding: Region Stockholm, Formas, Cancerfonden, Forte

Maternal and Child Health:

This theme focuses on uncovering the developmental origins of health and evaluating the performance of maternal and child health systems. We investigate the perinatal health effects of infections, smokeless nicotine, drug use, and other healthcare interventions during pregnancy. Additionally, we assess the longer-term impacts of reproductive and child health care and early life conditions on population health and welfare. Our methodology involves employing a variety of quantitative methods for causal inference, such as target trial emulation and genetically informative study designs.

Funding: NIH, VR

 

SNPVAL 

A research study conducted to determine the effectiveness of questions about snus use asked to pregnant women. This is achieved by retrieving the answers to the questions from the Medical Birth Register, which is maintained by the National Board of Health and Welfare, and matching them with blood samples analysed for the presence of cotinine. Cotinine is found in the blood if a person has used a product containing nicotine. It can also be found in the blood if a person has inhaled cigarette smoke from someone else. The blood samples are taken from biobanks, where they are stored after being collected by maternal healthcare services. Biobanks are places where blood samples and other biological material are stored for research purposes. When the sample was taken by maternal health care, it was to ensure that the pregnant woman had antibodies against rubella (German measles).

Information for research participants in the SNPVAL study (Swedish)

Research news and activities

Keywords:
Cardiometabolic Risk Factors Childbirth and Maternity care Epidemiology Obesity Psychiatry Public Health Public Health, Global Health and Social Medicine Sport and Fitness Sciences Tobacco Use Show all
Content reviewer:
05-11-2024