Susanna Brighenti

Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Artiklar

Journal article: SCIENTIFIC REPORTS. 2024;14(1):28150
Sirtuin inhibitors reduce intracellular growth of M. tuberculosis in human macrophages via modulation of host cell immunity
Kalsum S; Akber M; Loreti MG; Andersson B; Danielson E; Lerm M; Brighenti S
Article: JOURNAL OF INFECTIOUS DISEASES. 2024;230(2):e318-e326
Type I Interferon Autoantibodies Correlate With Cellular Immune Alterations in Severe COVID-19
Strunz B; Maucourant C; Mehta A; Wan H; Du L; Sun D; Chen P; Nordlander A; Gao Y; Cornillet M; Bister J; Kvedaraite E; Christ W; Klingstrom J; Geanon D; Parke A; Ekwall-Larson A; Rivino L; MacAry PA; Aleman S; Buggert M; Ljunggren H-G; Pan-Hammarstrom Q; Lund-Johansen F; Stralin K; Bjorkstrom NK
Article: IMMUNOBIOLOGY. 2023;228(2):152350
Immune cell landscape in symptomatic and asymptomatic SARS-CoV-2 infected adults and children in urban Dhaka, Bangladesh
Akhtar E; Mily A; Sarker P; Chanda BC; Haque F; Kuddusi RU; Haq MA; Lourda M; Brighenti S; Raqib R
Article: RESPIRATORY RESEARCH. 2023;24(1):62
Targeted plasma proteomics reveals signatures discriminating COVID-19 from sepsis with pneumonia
Palma Medina LM; Babacic H; Dzidic M; Parke A; Garcia M; Maleki KT; Unge C; Lourda M; Kvedaraite E; Chen P; Muvva JR; Cornillet M; Emgard J; Moll K; Michaelsson J; Flodstrom-Tullberg M; Brighenti S; Buggert M; Mjosberg J; Malmberg K-JK; Sandberg J; Gredmark-Russ S; Rooyackers O; Svensson MJ; Chambers BI; Eriksson L; Pernemalm MK; Bjorkstrom N; Aleman S; Ljunggren H-G; Klingstrom J; Stralin K; Norrby-Teglund A
Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1296501
Inflammatory immune profiles associated with disease severity in pulmonary tuberculosis patients with moderate to severe clinical TB or anemia
Ashenafi S; Loreti MG; Bekele A; Aseffa G; Amogne W; Kassa E; Aderaye G; Brighenti S
Article: MBIO. 2022;13(5):e0108622-e01022
High Glucose and Carbonyl Stress Impair HIF-1-Regulated Responses and the Control of Mycobacterium tuberculosis in Macrophages
Teran G; Li H; Catrina S-B; Liu R; Brighenti S; Zheng X; Grunler J; Nylen S; Carow B; Rottenberg ME
Article: NUTRIENTS. 2022;14(16):3318
Anemia Is a Strong Predictor of Wasting, Disease Severity, and Progression, in Clinical Tuberculosis (TB)
Ashenafi S; Bekele A; Aseffa G; Amogne W; Kassa E; Aderaye G; Worku A; Bergman P; Brighenti S
Article: AMERICAN JOURNAL OF PATHOLOGY. 2022;192(4):653-670
Immunosuppressive Features of the Microenvironment in Lymph Nodes Granulomas from Tuberculosis and HIV-Co-Infected Patients
Ashenafi S; Muvva JR; Mily A; Snall J; Zewdie M; Chanyalew M; Rehn A; Rahman S; Aseffa G; Bekele A; Aderaye G; Lema B; Svensson M; Brighenti S
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(40):e2109123118
High-dimensional profiling reveals phenotypic heterogeneity and disease-specific alterations of in COVID-19
Lourda M; Dzidic M; Hertwig L; Bergsten H; Medina LMP; Sinha I; Kvedaraite E; Chen P; Muvva JR; Gorin J-B; Cornillet M; Emgard J; Moll K; Garcia M; Maleki KT; Klingstrom J; Michaelsson J; Flodstrom-Tullberg M; Brighenti S; Buggert M; Mjosberg J; Malmberg K-J; Sandberg JK; Henter J-I; Folkesson E; Gredmark-Russ S; Sonnerborg A; Eriksson LI; Rooyackers O; Aleman S; Stralin K; Ljunggren H-G; Bjorkstrom NK; Svensson M; Ponzetta A; Norrby-Teglund A; Chambers BJ
Article: JOURNAL OF INFECTIOUS DISEASES. 2021;224(2):332-344
Immunomodulatory Agents Combat Multidrug-Resistant Tuberculosis by Improving Antimicrobial Immunity
Muvva JR; Ahmed S; Rekha RS; Kalsum S; Groenheit R; Schon T; Agerberth B; Bergman P; Brighenti S
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(6):e2018587118
Major alterations in the mononuclear phagocyte landscape associated with COVID-19 severity
Kvedaraite E; Hertwig L; Sinha I; Ponzetta A; Myrberg IH; Lourda M; Dzidic M; Akber M; Klingstrom J; Folkesson E; Muvva JR; Chen P; Gredmark-Russ S; Brighenti S; Norrby-Teglund A; Eriksson LI; Rooyackers O; Aleman S; Stralin K; Ljunggren H-G; Ginhoux F; Bjorkstrom NK; Henter J-I; Svensson M
Article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2021;10(7):e1306
SARS-CoV-2-specific humoral and cellular immunity persists through 9 months irrespective of COVID-19 severity at hospitalisation
Sandberg JT; Varnaite R; Christ W; Chen P; Muvva JR; Maleki KT; Garcia M; Dzidic M; Folkesson E; Skagerberg M; Ahlen G; Frelin L; Sallberg M; Eriksson LI; Rooyackers O; Sonnerborg A; Buggert M; Bjorkstrom NK; Aleman S; Stralin K; Klingstrom J; Ljunggren H-G; Blom K; Gredmark-Russ S
Article: BMC INFECTIOUS DISEASES. 2020;20(1):933
Slow radiological improvement and persistent low-grade inflammation after chemotherapy in tuberculosis patients with type 2 diabetes
Mily A; Sarker P; Taznin I; Hossain D; Haq MA; Kamal SMM; Agerberth B; Brighenti S; Raqib R
Article: CELL. 2020;183(1):158-168.e14
Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19
Sekine T; Perez-Potti A; Rivera-Ballesteros O; Stralin K; Gorin J-B; Olsson A; Llewellyn-Lacey S; Kamal H; Bogdanovic G; Muschiol S; Wullimann DJ; Kammann T; Emgard J; Parrot T; Folkesson E; Rooyackers O; Eriksson LI; Henter J-I; Sonnerborg A; Allander T; Albert J; Nielsen M; Klingstrom J; Gredmark-Russ S; Bjorkstrom NK; Sandberg JK; Price DA; Ljunggren H-G; Aleman S; Buggert M
Article: SCIENCE IMMUNOLOGY. 2020;5(51):eabe1670
MAIT cell activation and dynamics associated with COVID-19 disease severity
Parrot T; Gorin J-B; Ponzetta A; Maleki KT; Kammann T; Emgard J; Perez-Potti A; Sekine T; Rivera-Ballesteros O; Gredmark-Russ S; Rooyackers O; Folkesson E; Eriksson LI; Norrby-Teglund A; Ljunggren H-G; Bjorkstrom NK; Aleman S; Buggert M; Klingstrom J; Stralin K; Sandberg JK
Journal article: JOURNAL OF VISUALIZED EXPERIMENTS. 2020;(163)
Polarization of M1 and M2 Human Monocyte-Derived Cells and Analysis with Flow Cytometry upon Mycobacterium tuberculosis Infection
Mily A; Kalsum S; Loreti MG; Rekha RS; Muvva JR; Lourda M; Brighenti S
Article: JOURNAL OF VISUALIZED EXPERIMENTS. 2020;(163)
Polarization of M1 and M2 Human Monocyte-Derived Cells and Analysis with Flow Cytometry upon Mycobacterium tuberculosis Infection
Mily A; Kalsum S; Loreti MG; Rekha RS; Muvva JR; Lourda M; Brighenti S
Article: SCIENCE IMMUNOLOGY. 2020;5(50):eabd6832
Natural killer cell immunotypes related to COVID-19 disease severity
Maucourant C; Filipovic I; Ponzetta A; Aleman S; Cornillet M; Hertwig L; Strunz B; Lentini A; Reinius B; Brownlie D; Cuapio A; Ask EH; Hull RM; Haroun-Izquierdo A; Schaffer M; Klingstrom J; Folkesson E; Buggert M; Sandberg JK; Eriksson LI; Rooyackers O; Ljunggren H-G; Malmberg K-J; Michaelsson J; Marquardt N; Hammer Q; Stralin K; Bjorkstrom NK
Article: NUTRIENTS. 2019;11(7):E1675-1675
Vitamin D and Phenylbutyrate Supplementation Does Not Modulate Gut Derived Immune Activation in HIV-1
Missailidis C; Sorensen N; Ashenafi S; Amogne W; Kassa E; Bekele A; Getachew M; Gebreselassie N; Aseffa A; Aderaye G; Andersson J; Brighenti S; Bergman P
Article: NUTRIENTS. 2019;11(1):E133-133
Daily Nutritional Supplementation with Vitamin D₃ and Phenylbutyrate to Treatment-Naive HIV Patients Tested in a Randomized Placebo-Controlled Trial
Ashenafi S; Amogne W; Kassa E; Gebreselassie N; Bekele A; Aseffa G; Getachew M; Aseffa A; Worku A; Hammar U; Bergman P; Aderaye G; Andersson J; Brighenti S
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:3157
Polarization of Human Monocyte-Derived Cells With Vitamin D Promotes Control of Mycobacterium tuberculosis Infection
Rao Muvva J; Parasa VR; Lerm M; Svensson M; Brighenti S
Article: JOURNAL OF INTERNAL MEDICINE. 2018;284(3):292-306
Daily adjunctive therapy with vitamin D₃ and phenylbutyrate supports clinical recovery from pulmonary tuberculosis: a randomized controlled trial in Ethiopia
Bekele A; Gebreselassie N; Ashenafi S; Kassa E; Aseffa G; Amogne W; Getachew M; Aseffa A; Worku A; Raqib R; Agerberth B; Hammar U; Bergman P; Aderaye G; Andersson J; Brighenti S
Article: NUTRIENTS. 2018;10(6):E721-721
Vitamin D₃ Status and the Association with Human Cathelicidin Expression in Patients with Different Clinical Forms of Active Tuberculosis
Ashenafi S; Mazurek J; Rehn A; Lemma B; Aderaye G; Bekele A; Assefa G; Chanyalew M; Aseffa A; Andersson J; Bergman P; Brighenti S
Article: THE FASEB JOURNAL. 2018;32(5):2827-2840
Prostaglandin E₂ suppresses hCAP18/LL-37 expression in human macrophages via EP2/EP4: implications for treatment of Mycobacterium tuberculosis infection
Wan M; Tang X; Rekha RS; Muvva SSVJR; Brighenti S; Agerberth B; Haeggstrom JZ
Article: RESPIRATORY MEDICINE. 2018;138:S38-S44
Enhanced CD8⁺ cytolytic T cell responses in the peripheral circulation of patients with sarcoidosis and non-Lofgren's disease
Parasa VR; Forsslund H; Enger T; Lorenz D; Kullberg S; Eklund A; Skold M; Wahlstrom J; Grunewald J; Brighenti S
Article: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES. 2017;59:29-36
IL-7δ5 protein is expressed in human tissues and induces expression of the oxidized low density lipoprotein receptor 1 (OLR1) in CD14+monocytes
Rane L; Rahman S; Magalhaes I; Ambati A; Andersson J; Zumla A; Brighenti S; Maeurer MJ
Article: VACCINE. 2017;35(12):1652-1661
Safety and immunogenicity of the novel H4:IC31 tuberculosis vaccine candidate in BCG-vaccinated adults: Two phase I dose escalation trials
Norrby M; Vesikari T; Lindqvist L; Maeurer M; Ahmed R; Mandavifar S; Bennett S; McClain JB; Shepherd BM; Li D; Hokey DA; Kromann I; Hoff ST; Andersen P; de Visser AW; Joosten SA; Ottenhoff THM; Andersson J; Brighenti S
Article: FRONTIERS IN MICROBIOLOGY. 2017;8:2370
Inhibition of Tissue Matrix Metalloproteinases Interferes with Mycobacterium tuberculosis-Induced Granuloma Formation and Reduces Bacterial Load in a Human Lung Tissue Model
Parasa VR; Muvva JR; Rose JF; Braian C; Brighenti S; Lerm M
Article: MICROBIOLOGY SPECTRUM. 2016;4(6):10.1128/microbiolspec.tbt
Regulation of Immunity to Tuberculosis
Brighenti S; Ordway DJ
Article: ETHIOPIAN MEDICAL JOURNAL. 2016;54(4):181-188
LATENT TUBERCULOSIS AMONG ADULT ETHIOPIAN PATIENTS AT CHEST CLINIC, TIKURANBESSA SPECIALIZED HOSPITAL, ADDIS ABABA, ETHIOPIA.
Bekele A; Ashenafi S; Aderay G; Assefa G; Aseffa A; Anderssen J; Brighenti S
Article: CLINICAL INFECTIOUS DISEASES. 2015;61(Suppl 3):S225-S234
B in TB: B Cells as Mediators of Clinically Relevant Immune Responses in Tuberculosis
Rao M; Valentini D; Poiret T; Dodoo E; Parida S; Zumla A; Brighenti S; Maeurer M
Article: JOURNAL OF VISUALIZED EXPERIMENTS. 2015;(104):53084
A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
Braian C; Svensson M; Brighenti S; Lerm M; Parasa VR
Article: AUTOPHAGY. 2015;11(9):1688-1699
Phenylbutyrate induces LL-37-dependent autophagy and intracellular killing of Mycobacterium tuberculosis in human macrophages
Rekha RS; Muvva SSVJR; Wan M; Raqib R; Bergman P; Brighenti S; Gudmundsson GH; Agerberth B
Article: CLINICAL IMMUNOLOGY. 2015;156(2):85-97
Pulmonary tuberculosis patients with a Vitamin D deficiency demonstrate low local expression of the antimicrobial peptide LL-37 but enhanced FoxP3⁺ regulatory T cells and IgG-secreting cells
Rahman S; Rehn A; Rahman J; Andersson J; Svensson M; Brighenti S
Article: PLOS ONE. 2015;10(9):e0138340
Significant Effects of Oral Phenylbutyrate and Vitamin D3 Adjunctive Therapy in Pulmonary Tuberculosis: A Randomized Controlled Trial
Mily A; Rekha RS; Kamal SMM; Arifuzzaman ASM; Rahim Z; Khan L; Haq MA; Zaman K; Bergman P; Brighenti S; Gudmundsson GH; Agerberth B; Raqib R
Article: CLINICAL IMMUNOLOGY. 2014;151(2):84-99
Progression of clinical tuberculosis is associated with a Th2 immune response signature in combination with elevated levels of SOCS3
Ashenafi S; Aderaye G; Bekele A; Zewdie M; Aseffa G; Anh TNH; Carow B; Habtamu M; Wijkander M; Rottenberg M; Aseffa A; Andersson J; Svensson M; Brighenti S
Article: DISEASE MODELS & MECHANISMS. 2014;7(2):281-288
Modeling Mycobacterium tuberculosis early granuloma formation in experimental human lung tissue
Parasa VR; Rahman MJ; Anh TNH; Svensson M; Brighenti S; Lerm M
Article: THORAX. 2013;68(3):269-276
BCG-specific IgG-secreting peripheral plasmablasts as a potential biomarker of active tuberculosis in HIV negative and HIV positive patients
Ashenafi S; Aderaye G; Zewdie M; Raqib R; Bekele A; Magalhaes I; Lema B; Habtamu M; Rekha RS; Aseffa G; Maeurer M; Aseffa A; Svensson M; Andersson J; Brighenti S
Article: JOURNAL OF INFECTIOUS DISEASES. 2012;205:S316-S324
Local Immune Responses in Human Tuberculosis: Learning From the Site of Infection
Brighenti S; Andersson J
Article: MOLECULAR MEDICINE. 2012;18(4):647-658
Prime-Boost Vaccination with rBCG/rAd35 Enhances CD8⁺ Cytolytic T-Cell Responses in Lesions from Mycobacterium Tuberculosis-Infected Primates
Rahman S; Magalhaes I; Rahman J; Ahmed RK; Sizemore DR; Scanga CA; Weichold F; Verreck F; Kondova I; Sadoff J; Thorstensson R; Spangberg M; Svensson M; Andersson J; Maeurer M; Brighenti S
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2012;132(1):114-123
Plasmacytoid Dendritic Cells Infiltrate the Skin in Positive Tuberculin Skin Test Indurations
Bond E; Liang F; Sandgren KJ; Smed-Sorensen A; Bergman P; Brighenti S; Adams WC; Betemariam SA; Rangaka MX; Lange C; Wilkinson RJ; Andersson J; Lore K
Article: GENES AND IMMUNITY. 2011;12(7):513-522
Increased (6 exon) interleukin-7 production after M. tuberculosis infection and soluble interleukin-7 receptor expression in lung tissue
Rane L; Rahman S; Magalhaes I; Ahmed R; Spangberg M; Kondova I; Verreck F; Andersson J; Brighenti S; Maeurer MJ
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2010;396(1):50-57
Induction and regulation of CD8+cytolytic T cells in human tuberculosis and HIV infection
Brighenti S; Andersson J
Article: AMERICAN JOURNAL OF PATHOLOGY. 2009;174(6):2211-2224
Compartmentalization of Immune Responses in Human Tuberculosis Few CD8 + Effector T Cells but Elevated Levels of FbxP3 + Regulatory T Cells in the Granulomatous Lesions
Rahman S; Gudetta B; Fink J; Granath A; Ashenafi S; Aseffa A; Derbew M; Svensson M; Andersson J; Brighenti SG
Article: INFECTION AND IMMUNITY. 2007;75(11):5210-5222
Impaired expression of perforin and granulysin in CD8⁺ T cells at the site of infection in human chronic pulmonary tuberculosis
Andersson J; Samarina A; Fink J; Rahman S; Grundstroem S
Article: MICROBES AND INFECTION. 2006;8(8):1985-1993
Enhanced susceptibility of multidrug resistant strains of Mycobacterium tuberculosis to granulysin peptides correlates with a reduced fitness phenotype
Toro JC; Hoffner S; Linde C; Andersson M; Andersson J; Grundstrom S
Article: INFECTION AND IMMUNITY. 2005;73(10):6332-6339
Conserved structure and function in the granulysin and NK-lysin peptide family
Linde CMA; Grundström S; Nordling E; Refai E; Brennan PJ; Andersson M
Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2005;302(1-2):13-25
Detection of human perforin by ELISpot and ELISA:: Ex vivo identification of virus-specific cells
Zuber B; Levitsky V; Jönsson G; Paulie S; Samarina A; Grundström S; Metkar S; Norell H; Callender GG; Froelich C; Ahlborg N
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2004;279(9):8460-8468
Bcl-3 and NFκB p50-p50 homodimers act as transcriptional repressors in tolerant CD4⁺ T cells
Grundström S; Anderson P; Scheipers P; Sundstedt A
Article: JOURNAL OF IMMUNOLOGY. 2003;170(10):5008-5017
Superantigen-induced regulatory T cells display different suppressive functions in the presence or absence of natural CD4⁺CD25⁺ regulatory T cells in vivo
Grundström S; Cederbom L; Sundstedt A; Scheipers P; Ivars F
Article: JOURNAL OF IMMUNOLOGY. 2000;164(3):1175-1184
IL-2 unresponsiveness in anergic CD4⁺ T cells is due to defective signaling through the common γ-chain of the IL-2 receptor
Grundström S; Dohlsten M; Sundstedt A
Article: IMMUNOLOGY. 1998;95(1):76-82
T cell- and perforin-dependent depletion of B cells in vivo by staphylococcal enterotoxin A
Sundstedt A; Grundström S; Dohlsten M
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Alla övriga publikationer

Review: FRONTIERS IN IMMUNOLOGY. 2022;13:1059725
Reinventing the human tuberculosis (TB) granuloma: Learning from the cancer field
Ashenafi S; Brighenti S
Corrigendum: JOURNAL OF VISUALIZED EXPERIMENTS. 2020;(164)
Polarization of M1 and M2 Human Monocyte-Derived Cells and Analysis with Flow Cytometry upon Mycobacterium tuberculosis Infection (Sep, 10.3791/61807, 2020)
Mily A; Kalsum S; Loreti MG; Rekha RS; Muvva JR; Lourda M; Brighenti S
Editorial comment: NUTRIENTS. 2020;12(6):E1682-1682
Targeted Nutrition in Chronic Disease
Bergman P; Brighenti S
Review: FRONTIERS IN MEDICINE. 2020;7:537
Host and Pathogen Communication in the Respiratory Tract: Mechanisms and Models of a Complex Signaling Microenvironment
Berry SB; Haack AJ; Theberge AB; Brighenti S; Svensson M
Editorial comment: JOURNAL OF INTERNAL MEDICINE. 2018;284(2):113-115
Toward the understanding of human tuberculosis
Brighenti S; Lerm M
Review: JOURNAL OF INTERNAL MEDICINE. 2018;284(2):163-188
Perspectives for personalized therapy for patients with multidrug-resistant tuberculosis
Lange C; Alghamdi WA; Al-Shaer MH; Brighenti S; Diacon AH; DiNardo AR; Grobbel HP; Groschel MI; von Groote-Bidlingmaier F; Hauptmann M; Heyckendorf J; Kohler N; Kohl TA; Merker M; Niemann S; Peloquin CA; Reimann M; Schaible UE; Schaub D; Schleusener V; Thye T; Schon T
Review: JOURNAL OF INTERNAL MEDICINE. 2018;284(2):145-162
Vitamin D and tuberculosis: where next?
Brighenti S; Bergman P; Martineau AR
Review: JOURNAL OF INTERNAL MEDICINE. 2018;284(2):125-144
Friends and foes of tuberculosis: modulation of protective immunity
Brighenti S; Joosten SA
Book chapter: TUBERCULOSIS AND THE TUBERCLE BACILLUS. 2017;p. 73-93
Regulation of Immunity to Tuberculosis
Brighenti S; Ordway DJ
Review: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES. 2017;56:140-154
Peptide microarray-based characterization of antibody responses to host proteins after bacille Calmette-Guerin vaccination
Valentini D; Rao M; Rane L; Rahman S; Axelsson-Robertson R; Heuchel R; Lohr M; Hoft D; Brighenti S; Zumla A; Maeurer M
Review: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES. 2017;56:167-175
Humoral immune profiling of mycobacterial antigen recognition in sarcoidosis and Lofgren's syndrome using high-content peptide microarrays
Ferrara G; Valentini D; Rao M; Wahlstrom J; Grunewald J; Larsson L-O; Brighenti S; Dodoo E; Zumla A; Maeurer M
Letter: THORAX. 2011;66(8):727-729
A new potential biomarker for childhood tuberculosis
Thomas T; Brighenti S; Andersson J; Sack D; Raqib R
Review: CURRENT HIV/AIDS REPORTS. 2006;3(1):32-38
Studies of HIV-associated immune responses in lymphoid compartments.
Grundström S; Andersson J

Forskningsbidrag

Immune profiling and immune checkpoint modulation of multidrug-resistant tuberculosis infection (IPIM)
Swedish Research Council
1 January 2023 - 31 December 2026
Discovery of epigenetic modulators designed to treat and cure different tuberculosis endotypes by improving antimicrobial cellular immunity
Swedish Research Council
1 December 2022 - 30 November 2025
Towards two-step combination treatment with epigenetic- and immune-modulating drugs to promote cure and prevent antibiotic resistance in tuberculosis
Swedish Research Council
1 January 2020 - 31 December 2022
Exploring epigenetic alterations of cellular immunity in multidrug-resistant tuberculosis with relevance for new therapy using epigenetic- and immune-modulating drugs
Swedish Research Council
1 January 2020 - 31 December 2022
Mot två-stegs kombinationsbehandling med preparat som har epigenetiska- och immunmodulerande egenskaper som kan stödja utläkning av samt förhindra utveckling av antibiotika resistent tuberkulos
Swedish Heart-Lung Foundation
1 January 2020 - 31 December 2022
Mot två-stegs kombinationsbehandling med preparat som har epigenetiska- och immunmodulerandeegenskaper som kan stödja utläkning av samt förhindra utveckling av antibiotika resistent tuberkulos
Swedish Heart-Lung Foundation
1 January 2020 - 31 December 2022
10th International Conference on the Pathogenesis of Mycobacterial Infections
Swedish Research Council
1 November 2016 - 30 November 2016
An innovative human lung tissue model for tuberculosis research
Swedish Research Council
1 January 2015 - 31 December 2017
Discovery of immunopathogenesis in human tuberculosis: new concepts for diagnosis and treatment
Swedish Research Council
1 January 2015 - 31 December 2017
The role of diabetes-associated pathology in the development of clinical tuberculosis: a collaborative project between Sweden and Bangladesh
Swedish Research Council
1 January 2015 - 31 December 2018
Innovative human lung tissue model for tuberculosis research
Swedish Research Council
1 January 2013 - 31 December 2014
Novel treatment of infectious diseases via induction of mucosal immunity
Swedish Research Council
1 January 2013 - 31 December 2015
Discovery of pathogenesis in human tuberculosis with novel implications for clinical practise
Swedish Research Council
1 January 2012 - 31 December 2014
8th International Conference on the Pathogenesis of Mycobacterial Infections
Swedish Research Council
1 July 2010 - 31 December 2010
Studies of dysfunctional immunity in HIV disease with implications for immune reconstitution and vaccine development
Swedish Research Council
1 January 2010 - 31 December 2012

Anställningar

Senior Forskare, Immunsvar vid tuberkulos (TB), Medicin, Huddinge, Karolinska Institutet, 2014-

Examina och utbildning

Docent, Immunologi, Karolinska Institutet, 2014

Artiklar

Alla övriga publikationer

Forskningsbidrag

Anställningar

Examina och utbildning

Nyheter från KI

Kalenderhändelser från KI