Susanna Brighenti

About me
Publications
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Public outreach and news

About me

Immunologist with a research focus on tuberculosis (TB) infection and disease who has a large interest in basic and clinical research.

Research

My group study immunopathogenesis in TB and how immune responses that are suppressed by M. tuberculosis can be restored to support antibiotic treatment and prevent the mergence of antimicrobial resistance.

Teaching

Extensive experience of teaching and education including supervision of PhD students at Karolinska Institutet.

Articles

Journal article: SCIENTIFIC REPORTS. 2024;14(1):28150
Sirtuin inhibitors reduce intracellular growth of M. tuberculosis in human macrophages via modulation of host cell immunity.
Kalsum S; Akber M; Loreti MG; Andersson B; Danielson E; Lerm M; Brighenti S
Article: JOURNAL OF INFECTIOUS DISEASES. 2024;230(2):e318-e326
Type I Interferon Autoantibodies Correlate With Cellular Immune Alterations in Severe COVID-19
Strunz B; Maucourant C; Mehta A; Wan H; Du L; Sun D; Chen P; Nordlander A; Gao Y; Cornillet M; Bister J; Kvedaraite E; Christ W; Klingstrom J; Geanon D; Parke A; Ekwall-Larson A; Rivino L; MacAry PA; Aleman S; Buggert M; Ljunggren H-G; Pan-Hammarstrom Q; Lund-Johansen F; Stralin K; Bjorkstrom NK
Article: IMMUNOBIOLOGY. 2023;228(2):152350
Immune cell landscape in symptomatic and asymptomatic SARS-CoV-2 infected adults and children in urban Dhaka, Bangladesh
Akhtar E; Mily A; Sarker P; Chanda BC; Haque F; Kuddusi RU; Haq MA; Lourda M; Brighenti S; Raqib R
Article: RESPIRATORY RESEARCH. 2023;24(1):62
Targeted plasma proteomics reveals signatures discriminating COVID-19 from sepsis with pneumonia
Palma Medina LM; Babacic H; Dzidic M; Parke A; Garcia M; Maleki KT; Unge C; Lourda M; Kvedaraite E; Chen P; Muvva JR; Cornillet M; Emgard J; Moll K; Michaelsson J; Flodstrom-Tullberg M; Brighenti S; Buggert M; Mjosberg J; Malmberg K-JK; Sandberg J; Gredmark-Russ S; Rooyackers O; Svensson MJ; Chambers BI; Eriksson L; Pernemalm MK; Bjorkstrom N; Aleman S; Ljunggren H-G; Klingstrom J; Stralin K; Norrby-Teglund A
Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1296501
Inflammatory immune profiles associated with disease severity in pulmonary tuberculosis patients with moderate to severe clinical TB or anemia
Ashenafi S; Loreti MG; Bekele A; Aseffa G; Amogne W; Kassa E; Aderaye G; Brighenti S
Article: MBIO. 2022;13(5):e0108622-e01022
High Glucose and Carbonyl Stress Impair HIF-1-Regulated Responses and the Control of Mycobacterium tuberculosis in Macrophages
Teran G; Li H; Catrina S-B; Liu R; Brighenti S; Zheng X; Grunler J; Nylen S; Carow B; Rottenberg ME
Article: NUTRIENTS. 2022;14(16):3318
Anemia Is a Strong Predictor of Wasting, Disease Severity, and Progression, in Clinical Tuberculosis (TB)
Ashenafi S; Bekele A; Aseffa G; Amogne W; Kassa E; Aderaye G; Worku A; Bergman P; Brighenti S
Article: AMERICAN JOURNAL OF PATHOLOGY. 2022;192(4):653-670
Immunosuppressive Features of the Microenvironment in Lymph Nodes Granulomas from Tuberculosis and HIV-Co-Infected Patients
Ashenafi S; Muvva JR; Mily A; Snall J; Zewdie M; Chanyalew M; Rehn A; Rahman S; Aseffa G; Bekele A; Aderaye G; Lema B; Svensson M; Brighenti S
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(40):e2109123118
High-dimensional profiling reveals phenotypic heterogeneity and disease-specific alterations of in COVID-19
Lourda M; Dzidic M; Hertwig L; Bergsten H; Medina LMP; Sinha I; Kvedaraite E; Chen P; Muvva JR; Gorin J-B; Cornillet M; Emgard J; Moll K; Garcia M; Maleki KT; Klingstrom J; Michaelsson J; Flodstrom-Tullberg M; Brighenti S; Buggert M; Mjosberg J; Malmberg K-J; Sandberg JK; Henter J-I; Folkesson E; Gredmark-Russ S; Sonnerborg A; Eriksson LI; Rooyackers O; Aleman S; Stralin K; Ljunggren H-G; Bjorkstrom NK; Svensson M; Ponzetta A; Norrby-Teglund A; Chambers BJ
Article: JOURNAL OF INFECTIOUS DISEASES. 2021;224(2):332-344
Immunomodulatory Agents Combat Multidrug-Resistant Tuberculosis by Improving Antimicrobial Immunity
Muvva JR; Ahmed S; Rekha RS; Kalsum S; Groenheit R; Schon T; Agerberth B; Bergman P; Brighenti S
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(6):e2018587118
Major alterations in the mononuclear phagocyte landscape associated with COVID-19 severity
Kvedaraite E; Hertwig L; Sinha I; Ponzetta A; Myrberg IH; Lourda M; Dzidic M; Akber M; Klingstrom J; Folkesson E; Muvva JR; Chen P; Gredmark-Russ S; Brighenti S; Norrby-Teglund A; Eriksson LI; Rooyackers O; Aleman S; Stralin K; Ljunggren H-G; Ginhoux F; Bjorkstrom NK; Henter J-I; Svensson M
Article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2021;10(7):e1306
SARS-CoV-2-specific humoral and cellular immunity persists through 9 months irrespective of COVID-19 severity at hospitalisation
Sandberg JT; Varnaite R; Christ W; Chen P; Muvva JR; Maleki KT; Garcia M; Dzidic M; Folkesson E; Skagerberg M; Ahlen G; Frelin L; Sallberg M; Eriksson LI; Rooyackers O; Sonnerborg A; Buggert M; Bjorkstrom NK; Aleman S; Stralin K; Klingstrom J; Ljunggren H-G; Blom K; Gredmark-Russ S
Article: BMC INFECTIOUS DISEASES. 2020;20(1):933
Slow radiological improvement and persistent low-grade inflammation after chemotherapy in tuberculosis patients with type 2 diabetes
Mily A; Sarker P; Taznin I; Hossain D; Haq MA; Kamal SMM; Agerberth B; Brighenti S; Raqib R
Article: CELL. 2020;183(1):158-168.e14
Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19
Sekine T; Perez-Potti A; Rivera-Ballesteros O; Stralin K; Gorin J-B; Olsson A; Llewellyn-Lacey S; Kamal H; Bogdanovic G; Muschiol S; Wullimann DJ; Kammann T; Emgard J; Parrot T; Folkesson E; Rooyackers O; Eriksson LI; Henter J-I; Sonnerborg A; Allander T; Albert J; Nielsen M; Klingstrom J; Gredmark-Russ S; Bjorkstrom NK; Sandberg JK; Price DA; Ljunggren H-G; Aleman S; Buggert M
Article: SCIENCE IMMUNOLOGY. 2020;5(51):eabe1670
MAIT cell activation and dynamics associated with COVID-19 disease severity
Parrot T; Gorin J-B; Ponzetta A; Maleki KT; Kammann T; Emgard J; Perez-Potti A; Sekine T; Rivera-Ballesteros O; Gredmark-Russ S; Rooyackers O; Folkesson E; Eriksson LI; Norrby-Teglund A; Ljunggren H-G; Bjorkstrom NK; Aleman S; Buggert M; Klingstrom J; Stralin K; Sandberg JK
Journal article: JOURNAL OF VISUALIZED EXPERIMENTS. 2020;(163)
Polarization of M1 and M2 Human Monocyte-Derived Cells and Analysis with Flow Cytometry upon Mycobacterium tuberculosis Infection
Mily A; Kalsum S; Loreti MG; Rekha RS; Muvva JR; Lourda M; Brighenti S
Article: JOURNAL OF VISUALIZED EXPERIMENTS. 2020;(163)
Polarization of M1 and M2 Human Monocyte-Derived Cells and Analysis with Flow Cytometry upon Mycobacterium tuberculosis Infection
Mily A; Kalsum S; Loreti MG; Rekha RS; Muvva JR; Lourda M; Brighenti S
Article: SCIENCE IMMUNOLOGY. 2020;5(50):eabd6832
Natural killer cell immunotypes related to COVID-19 disease severity
Maucourant C; Filipovic I; Ponzetta A; Aleman S; Cornillet M; Hertwig L; Strunz B; Lentini A; Reinius B; Brownlie D; Cuapio A; Ask EH; Hull RM; Haroun-Izquierdo A; Schaffer M; Klingstrom J; Folkesson E; Buggert M; Sandberg JK; Eriksson LI; Rooyackers O; Ljunggren H-G; Malmberg K-J; Michaelsson J; Marquardt N; Hammer Q; Stralin K; Bjorkstrom NK
Article: NUTRIENTS. 2019;11(7):E1675-1675
Vitamin D and Phenylbutyrate Supplementation Does Not Modulate Gut Derived Immune Activation in HIV-1
Missailidis C; Sorensen N; Ashenafi S; Amogne W; Kassa E; Bekele A; Getachew M; Gebreselassie N; Aseffa A; Aderaye G; Andersson J; Brighenti S; Bergman P
Article: NUTRIENTS. 2019;11(1):E133-133
Daily Nutritional Supplementation with Vitamin D₃ and Phenylbutyrate to Treatment-Naive HIV Patients Tested in a Randomized Placebo-Controlled Trial
Ashenafi S; Amogne W; Kassa E; Gebreselassie N; Bekele A; Aseffa G; Getachew M; Aseffa A; Worku A; Hammar U; Bergman P; Aderaye G; Andersson J; Brighenti S
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:3157
Polarization of Human Monocyte-Derived Cells With Vitamin D Promotes Control of Mycobacterium tuberculosis Infection
Rao Muvva J; Parasa VR; Lerm M; Svensson M; Brighenti S
Article: JOURNAL OF INTERNAL MEDICINE. 2018;284(3):292-306
Daily adjunctive therapy with vitamin D₃ and phenylbutyrate supports clinical recovery from pulmonary tuberculosis: a randomized controlled trial in Ethiopia
Bekele A; Gebreselassie N; Ashenafi S; Kassa E; Aseffa G; Amogne W; Getachew M; Aseffa A; Worku A; Raqib R; Agerberth B; Hammar U; Bergman P; Aderaye G; Andersson J; Brighenti S
Article: NUTRIENTS. 2018;10(6):E721-721
Vitamin D₃ Status and the Association with Human Cathelicidin Expression in Patients with Different Clinical Forms of Active Tuberculosis
Ashenafi S; Mazurek J; Rehn A; Lemma B; Aderaye G; Bekele A; Assefa G; Chanyalew M; Aseffa A; Andersson J; Bergman P; Brighenti S
Article: RESPIRATORY MEDICINE. 2018;138:S38-S44
Enhanced CD8⁺ cytolytic T cell responses in the peripheral circulation of patients with sarcoidosis and non-Lofgren's disease
Parasa VR; Forsslund H; Enger T; Lorenz D; Kullberg S; Eklund A; Skold M; Wahlstrom J; Grunewald J; Brighenti S
Article: THE FASEB JOURNAL. 2018;32(5):2827-2840
Prostaglandin E₂ suppresses hCAP18/LL-37 expression in human macrophages via EP2/EP4: implications for treatment of Mycobacterium tuberculosis infection
Wan M; Tang X; Rekha RS; Muvva SSVJR; Brighenti S; Agerberth B; Haeggstrom JZ
Article: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES. 2017;59:29-36
IL-7δ5 protein is expressed in human tissues and induces expression of the oxidized low density lipoprotein receptor 1 (OLR1) in CD14+monocytes
Rane L; Rahman S; Magalhaes I; Ambati A; Andersson J; Zumla A; Brighenti S; Maeurer MJ
Article: VACCINE. 2017;35(12):1652-1661
Safety and immunogenicity of the novel H4:IC31 tuberculosis vaccine candidate in BCG-vaccinated adults: Two phase I dose escalation trials
Norrby M; Vesikari T; Lindqvist L; Maeurer M; Ahmed R; Mandavifar S; Bennett S; McClain JB; Shepherd BM; Li D; Hokey DA; Kromann I; Hoff ST; Andersen P; de Visser AW; Joosten SA; Ottenhoff THM; Andersson J; Brighenti S
Article: FRONTIERS IN MICROBIOLOGY. 2017;8:2370
Inhibition of Tissue Matrix Metalloproteinases Interferes with Mycobacterium tuberculosis-Induced Granuloma Formation and Reduces Bacterial Load in a Human Lung Tissue Model
Parasa VR; Muvva JR; Rose JF; Braian C; Brighenti S; Lerm M
Article: MICROBIOLOGY SPECTRUM. 2016;4(6):10.1128/microbiolspec.tbt
Regulation of Immunity to Tuberculosis
Brighenti S; Ordway DJ
Article: ETHIOPIAN MEDICAL JOURNAL. 2016;54(4):181-188
LATENT TUBERCULOSIS AMONG ADULT ETHIOPIAN PATIENTS AT CHEST CLINIC, TIKURANBESSA SPECIALIZED HOSPITAL, ADDIS ABABA, ETHIOPIA.
Bekele A; Ashenafi S; Aderay G; Assefa G; Aseffa A; Anderssen J; Brighenti S
Article: CLINICAL INFECTIOUS DISEASES. 2015;61(Suppl 3):S225-S234
B in TB: B Cells as Mediators of Clinically Relevant Immune Responses in Tuberculosis
Rao M; Valentini D; Poiret T; Dodoo E; Parida S; Zumla A; Brighenti S; Maeurer M
Article: JOURNAL OF VISUALIZED EXPERIMENTS. 2015;(104):53084
A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
Braian C; Svensson M; Brighenti S; Lerm M; Parasa VR
Article: AUTOPHAGY. 2015;11(9):1688-1699
Phenylbutyrate induces LL-37-dependent autophagy and intracellular killing of Mycobacterium tuberculosis in human macrophages
Rekha RS; Muvva SSVJR; Wan M; Raqib R; Bergman P; Brighenti S; Gudmundsson GH; Agerberth B
Article: CLINICAL IMMUNOLOGY. 2015;156(2):85-97
Pulmonary tuberculosis patients with a Vitamin D deficiency demonstrate low local expression of the antimicrobial peptide LL-37 but enhanced FoxP3⁺ regulatory T cells and IgG-secreting cells
Rahman S; Rehn A; Rahman J; Andersson J; Svensson M; Brighenti S
Article: PLOS ONE. 2015;10(9):e0138340
Significant Effects of Oral Phenylbutyrate and Vitamin D3 Adjunctive Therapy in Pulmonary Tuberculosis: A Randomized Controlled Trial
Mily A; Rekha RS; Kamal SMM; Arifuzzaman ASM; Rahim Z; Khan L; Haq MA; Zaman K; Bergman P; Brighenti S; Gudmundsson GH; Agerberth B; Raqib R
Article: CLINICAL IMMUNOLOGY. 2014;151(2):84-99
Progression of clinical tuberculosis is associated with a Th2 immune response signature in combination with elevated levels of SOCS3
Ashenafi S; Aderaye G; Bekele A; Zewdie M; Aseffa G; Anh TNH; Carow B; Habtamu M; Wijkander M; Rottenberg M; Aseffa A; Andersson J; Svensson M; Brighenti S
Article: DISEASE MODELS & MECHANISMS. 2014;7(2):281-288
Modeling Mycobacterium tuberculosis early granuloma formation in experimental human lung tissue
Parasa VR; Rahman MJ; Anh TNH; Svensson M; Brighenti S; Lerm M
Article: THORAX. 2013;68(3):269-276
BCG-specific IgG-secreting peripheral plasmablasts as a potential biomarker of active tuberculosis in HIV negative and HIV positive patients
Ashenafi S; Aderaye G; Zewdie M; Raqib R; Bekele A; Magalhaes I; Lema B; Habtamu M; Rekha RS; Aseffa G; Maeurer M; Aseffa A; Svensson M; Andersson J; Brighenti S
Article: JOURNAL OF INFECTIOUS DISEASES. 2012;205:S316-S324
Local Immune Responses in Human Tuberculosis: Learning From the Site of Infection
Brighenti S; Andersson J
Article: MOLECULAR MEDICINE. 2012;18(4):647-658
Prime-Boost Vaccination with rBCG/rAd35 Enhances CD8⁺ Cytolytic T-Cell Responses in Lesions from Mycobacterium Tuberculosis-Infected Primates
Rahman S; Magalhaes I; Rahman J; Ahmed RK; Sizemore DR; Scanga CA; Weichold F; Verreck F; Kondova I; Sadoff J; Thorstensson R; Spangberg M; Svensson M; Andersson J; Maeurer M; Brighenti S
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2012;132(1):114-123
Plasmacytoid Dendritic Cells Infiltrate the Skin in Positive Tuberculin Skin Test Indurations
Bond E; Liang F; Sandgren KJ; Smed-Sorensen A; Bergman P; Brighenti S; Adams WC; Betemariam SA; Rangaka MX; Lange C; Wilkinson RJ; Andersson J; Lore K
Article: GENES AND IMMUNITY. 2011;12(7):513-522
Increased (6 exon) interleukin-7 production after M. tuberculosis infection and soluble interleukin-7 receptor expression in lung tissue
Rane L; Rahman S; Magalhaes I; Ahmed R; Spangberg M; Kondova I; Verreck F; Andersson J; Brighenti S; Maeurer MJ
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2010;396(1):50-57
Induction and regulation of CD8+cytolytic T cells in human tuberculosis and HIV infection
Brighenti S; Andersson J
Article: AMERICAN JOURNAL OF PATHOLOGY. 2009;174(6):2211-2224
Compartmentalization of Immune Responses in Human Tuberculosis Few CD8 + Effector T Cells but Elevated Levels of FbxP3 + Regulatory T Cells in the Granulomatous Lesions
Rahman S; Gudetta B; Fink J; Granath A; Ashenafi S; Aseffa A; Derbew M; Svensson M; Andersson J; Brighenti SG
Article: INFECTION AND IMMUNITY. 2007;75(11):5210-5222
Impaired expression of perforin and granulysin in CD8⁺ T cells at the site of infection in human chronic pulmonary tuberculosis
Andersson J; Samarina A; Fink J; Rahman S; Grundstroem S
Article: MICROBES AND INFECTION. 2006;8(8):1985-1993
Enhanced susceptibility of multidrug resistant strains of Mycobacterium tuberculosis to granulysin peptides correlates with a reduced fitness phenotype
Toro JC; Hoffner S; Linde C; Andersson M; Andersson J; Grundstrom S
Article: INFECTION AND IMMUNITY. 2005;73(10):6332-6339
Conserved structure and function in the granulysin and NK-lysin peptide family
Linde CMA; Grundström S; Nordling E; Refai E; Brennan PJ; Andersson M
Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2005;302(1-2):13-25
Detection of human perforin by ELISpot and ELISA:: Ex vivo identification of virus-specific cells
Zuber B; Levitsky V; Jönsson G; Paulie S; Samarina A; Grundström S; Metkar S; Norell H; Callender GG; Froelich C; Ahlborg N
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2004;279(9):8460-8468
Bcl-3 and NFκB p50-p50 homodimers act as transcriptional repressors in tolerant CD4⁺ T cells
Grundström S; Anderson P; Scheipers P; Sundstedt A
Article: JOURNAL OF IMMUNOLOGY. 2003;170(10):5008-5017
Superantigen-induced regulatory T cells display different suppressive functions in the presence or absence of natural CD4⁺CD25⁺ regulatory T cells in vivo
Grundström S; Cederbom L; Sundstedt A; Scheipers P; Ivars F
Article: JOURNAL OF IMMUNOLOGY. 2000;164(3):1175-1184
IL-2 unresponsiveness in anergic CD4⁺ T cells is due to defective signaling through the common γ-chain of the IL-2 receptor
Grundström S; Dohlsten M; Sundstedt A
Article: IMMUNOLOGY. 1998;95(1):76-82
T cell- and perforin-dependent depletion of B cells in vivo by staphylococcal enterotoxin A
Sundstedt A; Grundström S; Dohlsten M
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All other publications

Review: FRONTIERS IN IMMUNOLOGY. 2022;13:1059725
Reinventing the human tuberculosis (TB) granuloma: Learning from the cancer field
Ashenafi S; Brighenti S
Corrigendum: JOURNAL OF VISUALIZED EXPERIMENTS. 2020;(164)
Polarization of M1 and M2 Human Monocyte-Derived Cells and Analysis with Flow Cytometry upon Mycobacterium tuberculosis Infection (Sep, 10.3791/61807, 2020)
Mily A; Kalsum S; Loreti MG; Rekha RS; Muvva JR; Lourda M; Brighenti S
Editorial comment: NUTRIENTS. 2020;12(6):E1682-1682
Targeted Nutrition in Chronic Disease
Bergman P; Brighenti S
Review: FRONTIERS IN MEDICINE. 2020;7:537
Host and Pathogen Communication in the Respiratory Tract: Mechanisms and Models of a Complex Signaling Microenvironment
Berry SB; Haack AJ; Theberge AB; Brighenti S; Svensson M
Editorial comment: JOURNAL OF INTERNAL MEDICINE. 2018;284(2):113-115
Toward the understanding of human tuberculosis
Brighenti S; Lerm M
Review: JOURNAL OF INTERNAL MEDICINE. 2018;284(2):163-188
Perspectives for personalized therapy for patients with multidrug-resistant tuberculosis
Lange C; Alghamdi WA; Al-Shaer MH; Brighenti S; Diacon AH; DiNardo AR; Grobbel HP; Groschel MI; von Groote-Bidlingmaier F; Hauptmann M; Heyckendorf J; Kohler N; Kohl TA; Merker M; Niemann S; Peloquin CA; Reimann M; Schaible UE; Schaub D; Schleusener V; Thye T; Schon T
Review: JOURNAL OF INTERNAL MEDICINE. 2018;284(2):145-162
Vitamin D and tuberculosis: where next?
Brighenti S; Bergman P; Martineau AR
Review: JOURNAL OF INTERNAL MEDICINE. 2018;284(2):125-144
Friends and foes of tuberculosis: modulation of protective immunity
Brighenti S; Joosten SA
Book chapter: TUBERCULOSIS AND THE TUBERCLE BACILLUS. 2017;p. 73-93
Regulation of Immunity to Tuberculosis
Brighenti S; Ordway DJ
Review: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES. 2017;56:140-154
Peptide microarray-based characterization of antibody responses to host proteins after bacille Calmette-Guerin vaccination
Valentini D; Rao M; Rane L; Rahman S; Axelsson-Robertson R; Heuchel R; Lohr M; Hoft D; Brighenti S; Zumla A; Maeurer M
Review: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES. 2017;56:167-175
Humoral immune profiling of mycobacterial antigen recognition in sarcoidosis and Lofgren's syndrome using high-content peptide microarrays
Ferrara G; Valentini D; Rao M; Wahlstrom J; Grunewald J; Larsson L-O; Brighenti S; Dodoo E; Zumla A; Maeurer M
Letter: THORAX. 2011;66(8):727-729
A new potential biomarker for childhood tuberculosis
Thomas T; Brighenti S; Andersson J; Sack D; Raqib R
Review: CURRENT HIV/AIDS REPORTS. 2006;3(1):32-38
Studies of HIV-associated immune responses in lymphoid compartments.
Grundström S; Andersson J

Grants

Immune profiling and immune checkpoint modulation of multidrug-resistant tuberculosis infection (IPIM)
Swedish Research Council
1 January 2023 - 31 December 2026
Discovery of epigenetic modulators designed to treat and cure different tuberculosis endotypes by improving antimicrobial cellular immunity
Swedish Research Council
1 December 2022 - 30 November 2025
Towards two-step combination treatment with epigenetic- and immune-modulating drugs to promote cure and prevent antibiotic resistance in tuberculosis
Swedish Research Council
1 January 2020 - 31 December 2022
Exploring epigenetic alterations of cellular immunity in multidrug-resistant tuberculosis with relevance for new therapy using epigenetic- and immune-modulating drugs
Swedish Research Council
1 January 2020 - 31 December 2022
Mot två-stegs kombinationsbehandling med preparat som har epigenetiska- och immunmodulerande egenskaper som kan stödja utläkning av samt förhindra utveckling av antibiotika resistent tuberkulos
Swedish Heart-Lung Foundation
1 January 2020 - 31 December 2022
Mot två-stegs kombinationsbehandling med preparat som har epigenetiska- och immunmodulerandeegenskaper som kan stödja utläkning av samt förhindra utveckling av antibiotika resistent tuberkulos
Swedish Heart-Lung Foundation
1 January 2020 - 31 December 2022
10th International Conference on the Pathogenesis of Mycobacterial Infections
Swedish Research Council
1 November 2016 - 30 November 2016
An innovative human lung tissue model for tuberculosis research
Swedish Research Council
1 January 2015 - 31 December 2017
Discovery of immunopathogenesis in human tuberculosis: new concepts for diagnosis and treatment
Swedish Research Council
1 January 2015 - 31 December 2017
The role of diabetes-associated pathology in the development of clinical tuberculosis: a collaborative project between Sweden and Bangladesh
Swedish Research Council
1 January 2015 - 31 December 2018
Innovative human lung tissue model for tuberculosis research
Swedish Research Council
1 January 2013 - 31 December 2014
Novel treatment of infectious diseases via induction of mucosal immunity
Swedish Research Council
1 January 2013 - 31 December 2015
Discovery of pathogenesis in human tuberculosis with novel implications for clinical practise
Swedish Research Council
1 January 2012 - 31 December 2014
8th International Conference on the Pathogenesis of Mycobacterial Infections
Swedish Research Council
1 July 2010 - 31 December 2010
Studies of dysfunctional immunity in HIV disease with implications for immune reconstitution and vaccine development
Swedish Research Council
1 January 2010 - 31 December 2012

Employments

Principal Researcher, Immunology of tuberculosis (TB), Department of Medicine, Huddinge, Karolinska Institutet, 2014-

Degrees and Education

Docent, Karolinska Institutet, 2014

About me

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Degrees and Education

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