Laboratorium för groddlinjeutveckling och regenerering – João Pedro Alves-Lopes team

Publikationer

Alla gruppmedlemmars publikationer

• Journal article: HUMAN REPRODUCTION OPEN. 2026;:hoag054

  Human iPSCs derived from cryopreserved testicular somatic cells enable germline regeneration in childhood cancer survivors

  Macedo T; De Guidi C; Aodha LN; Boggavarapu NR; Piechocka M; Ye X; Mastropasqua F; Keros V; Nyström UN; Frisk P; Johansson P; Tammimies K; Baert Y; Jahnukainen K; Stukenborg J-B; Alves-Lopes JP
• Letter: LEUKEMIA. 2026;40(5):1044-1048

  Testicular organoids formation from leukaemia-infiltrated prepubertal testicular tissue: implications for fertility preservation

  Cui Y; Lohi J; Lindskog C; Jahnukainen K; Stukenborg J-B
• Article: BLOOD ADVANCES. 2026;10(7):2525-2537

  Allogeneic hematopoietic stem cell transplantation in ERCC6L2 disease

  Hakkarainen M; de Fontbrune FS; Kaaja I; Douglas S; Dalle J-H; Risitano AM; Kulasekararaj A; Alsultan A; Cutler C; Ho VT; Hellstrom-Lindberg E; Mielke S; Myhre AE; Rihani R; Abu Shanap M; Hashem H; Shimamura A; Rowe RG; Auer F; Beier F; Desnica L; Hough R; Jafri SRA; Ayas M; Jardine L; Mellid EF; Corrales I; Richardson D; Ozbek NY; Zaniewska-Tekieli A; Gozdzik J; Ryhanen S; Niinimaki R; Jahnukainen K; Salmenniemi U; Kilpivaara O; Wartiovaara-Kautto U
• Review: HUMAN REPRODUCTION UPDATE. 2026;32(2):129-153

  The road to restore male fertility using in vitro-derived germ cells

  Macedo T; Alves-Lopes JP
• Article: PEDIATRIC HEMATOLOGY AND ONCOLOGY. 2026;43(2):89-102

  Long-Term Health Outcomes in Male Survivors of Childhood Cancer After Hematopoietic Stem Cell Transplantation: A Registry-Based Study

  Koskela M; Korhonen M; Jahnukainen K
• Article: JOURNAL OF CANCER SURVIVORSHIP. 2026;20(1):12-19

  A 12-year overview of fertility preservation practice in Nordic pediatric oncology centers

  Asadi-Azarbaijani B; Oskam IC; Jahnukainen K
• Article: PEDIATRIC HEMATOLOGY AND ONCOLOGY. 2026;43(1):9-20

  Sexual activity in young adult survivors of childhood cancer: a population-based study

  Fagerkvist K; Haavisto A; Jahnukainen K; Axelsson O; Lampic C; Wettergren L
• Article: JOURNAL OF OVARIAN RESEARCH. 2025;19(1):15

  Micro-CT and machine learning: a high-throughput alternative to histology for follicle reserve assessment in cryopreserved ovarian tissue

  Knuus K; Nguyen M; Hannula M; Hassan J; Otala M; Tuuri T; Lundin K; Lahtinen A; Damdimopoulou P; Hyttinen J; Jahnukainen K
• Article: JCO ONCOLOGY PRACTICE. 2025;21(11):1681-1688

  Guidelines, Counseling Practices, and Fertility Preservation Options for Childhood Cancer Patients in the Nordic-Baltic Region

  Grubliauskaite M; Gudleviciene Z; Oskam IC; Asadi-Azarbaijani B; Jahnukainen K
• Article: CLINICAL EPIGENETICS. 2025;17(1):154

  Epigenetic risk stratification in juvenile myelomonocytic leukemia by targeted methylation analysis of the BMP4 locus.

  Ghanjati F; Heck A; Lebrecht D; Nöllke P; Andresen F; Rotari N; Schoof M; Schönung M; Lipka DB; Dworzak M; De Moerloose B; Sukova M; Hasle H; Jahnukainen K; Malone A; Masetti R; Buechner J; Ussowicz M; Catala A; Turkiewicz D; de Haas V; Schmugge M; Erlacher M; Niemeyer CM; Flotho C
• Journal article: MOLECULAR HUMAN REPRODUCTION. 2025;31(4):gaaf055

  An Nlrp5-null mutation leads to attenuated de novo methylation in oocytes, accompanied by a significant reduction in DNMT3L

  Nic Aodha L; Pokhilko A; Rosen LU; Galatidou S; Walewska E; Belton C; Galvao A; Okkenhaug H; Yu L; Nakhuda A; Mansfield B; Khan S; Oxley D; Barragan M; Kelsey G
• Article: BRITISH JOURNAL OF HAEMATOLOGY. 2025;207(4):1454-1463

  Characteristics and prognosis of paediatric normal karyotype acute myeloid leukaemia: A NOPHO-DBH AML study.

  Herlin MK; Kjeldsen E; Abrahamsson J; Arad-Cohen N; Cheuk D; De Moerloose B; Jahnukainen K; Jónsson ÓG; Kaspers GJL; Kovalova Z; Navarro JMF; Noren-Nyström U; Palle J; Pasaulienė R; Saks K; Zeller B; Holmfeldt L; Hasle H; Juul-Dam KL
• Article: ANDROLOGY. 2025;13(6):1575-1591

  Imatinib decreases germ cell survival and germline stem cell proliferation in rodent testis ex vivo and in vitro

  Eggert A; Laasanen S; Nurmio M; Wahlgren A; Jahnukainen K; Eerola K; Nieminen M; Olotu O; Kotaja N; Makela J-A; Toppari J
• Article: BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY. 2025;102:102638

  Is the time right for transplanting immature testicular tissue or cells to restore male fertility? Expert perspectives on clinical implementation of autotransplantation of cryopreserved testicular tissue or cells for fertility restoration

  Safrai M; Goossens E; Mitchell RT; Orwig KE; Mulderf CL; van Pelt AMM; Gookh DA; Feraillej A; Delgouffe E; Ginsberg JP; Stukenborg J-B; Duffin K; Jahnukainen K; Andersen CY; van de Wetering MD; Rimmer MP; Barraud-Lange V; Neuhaus N; Lane S; Sadri-Ardekani H; Rives N; Wyns C
• Review: DEVELOPMENT. 2025;152(17):dev204968

  Emerging principles and models of human primordial germ cell development

  Ramakrishna NB; Alves-Lopes JP; Gruhn WH
• Article: HUMAN REPRODUCTION. 2025;40(8):1467-1475

  Early transcriptional states of spermatogonia and marker expressions in the prepubertal human testis following chemotherapy-induced depletion

  Omar HB; Stevens J; Haavisto A; Cui Y; Harteveld F; Yang Y; Bjarnason R; Romerius P; Sundin M; Nystroem UN; Langenskioeld C; Vogt H; Frisk P; Vepsaelaeinen K; Petersen C; Cui L; Guo J; Jahnukainen K; Stukenborg J-B
• Article: HUMAN REPRODUCTION. 2025;40(8):1391-1431

  ESHRE good practice recommendations on fertility preservation involving testicular tissue cryopreservation in children receiving gonadotoxic therapies†

  Mitchell RT; Eguizabal C; Goossens E; Grynberg M; Jahnukainen K; Le Clef N; Mulder CL; Neuhaus N; Rimmer MP; Stukenborg J-B; van de Wetering MD; van Pelt AMM; Wyns C
• Article: CLINICAL TRANSPLANTATION. 2025;39(8):e70256

  Drug Usage and Risk for Polypharmacy After Pediatric Solid Organ Transplantation-A National Register Study.

  Salonen R; Endén K; Koskela M; Jahnukainen K; Nikkilä A; Jahnukainen T
• Article: BLOOD CANCER JOURNAL. 2025;15(1):121

  Age-dependent phenotypic and molecular evolution of pediatric MDS arising from GATA2 deficiency.

  Kotmayer L; Kozyra EJ; Kang G; Strahm B; Yoshimi A; Sahoo SS; Pastor VB; Attardi E; Voss R; Vinci L; Kaiser M; Dworzak MN; De Moerloose B; Sukova M; Starý J; Hasle H; Jahnukainen K; Polychronopoulou S; Kállay K; Smith OP; Malone A; Barzilai Birenboim S; Masetti R; Buechner J; Ussowicz M; Kjöllerström P; Bodova I; Kavcic M; Català A; Turkiewicz D; Schmugge M; de Haas V; Okhomina VI; Sotomayor C; Catalán P; Wehr C; Salzer U; Germing U; Gattermann N; Bödör C; Gray N; Lewis S; Shimamura A; Giorgetti A; Erlacher M; Niemeyer CM; Wlodarski MW
• Letter: BRITISH JOURNAL OF HAEMATOLOGY. 2025;207(2):636-641

  Impact of CHEK2 germline variants on haematological malignancy risk and outcomes of allogeneic HSCT

  Lahtinen AK; Karu M; Koski JR; Ritari J; Hyvarinen K; Koskela S; Nihtila J; Partanen J; Vettenranta K; Koskenvuo M; Niittyvuopio R; Salmenniemi U; Itala-Remes M; Jahnukainen K; Kilpivaara O; Wartiovaara-Kautto U
• Article: LAKARTIDNINGEN. 2025;122:24124

  [All childhood cancer survivors get at least one visit at follow-up clinics for adults].

  Jarfelt M; Hjorth L; Petersen C; Enskär K; Olsson M; Mattson M; Nath S; Herslow M
• Article: AMERICAN JOURNAL OF TRANSPLANTATION. 2025;25(4):767-779

  Clinical outcomes of pediatric kidney replacement therapy after childhood cancer-An ESPN/ERA Registry study.

  Kaijansinkko H; Bonthuis M; Jahnukainen K; Harambat J; Vidal E; Bakkaloglu SA; Inward C; Sinha MD; Roperto RM; Kuehni CE; Biró E; Kwon T; Mota C; Adams B; Szczepańska M; Bieniaś B; Höcker B; Fomina S; Gjerstad AC; Vondrak K; Alpay H; Plumb LA; Hommel K; Molchanova MS; Hubmann H; Alonso-Melgar A; Jager KJ; Jahnukainen T
• Article: INTERNATIONAL JOURNAL OF CANCER. 2025;156(6):1236-1246

  Influence of therapy exposures on specific late morbidities, prescription drug purchases, and mortality in aging male survivors of childhood cancer: A registry-based study

  Koskela M; Korhonen M; Haavisto A; Jahnukainen K
• Preprint: BIORXIV. 2025

  An Nlrp5-null mutation leads to attenuated de novo methylation in oocytes, accompanied by a significant reduction in DNMT3L

  Aodha LN; Pokhilko A; Rosen LU; Galatidou S; Walewska E; Belton C; Galvao A; Okkenhaug H; Yu L; Nakhuda A; Mansfield B; Khan S; Oxley D; Barragán M; Kelsey G
• Article: CHILD NEUROPSYCHOLOGY. 2025;31(1):53-79

  Generalizability of the Swedish WISC-V to the Finland-Swedish minority - the FinSwed study

  Rosenqvist J; Slama S; Haavisto A
• Article: CANCER. 2025;131(1):e35623

  Longitudinal trends in testicular volume z scores from puberty to adulthood, sperm quality, and paternity outcomes after childhood cancer

  Korhonen M; Jahnukainen K; Koskela M
• Review: CTS-CLINICAL AND TRANSLATIONAL SCIENCE. 2024;17(11):e70075

  Non-alkylating agents-induced gonadotoxicity in pre-pubertal males: Insights on the clinical and pre-clinical front

  Sriram S; Macedo T; Mavinkurve-Groothuis A; van de Wetering M; Looijenga LHJ
• Article: ANDROLOGY. 2024;12(8):1771-1779

  Pubertal testicular volume references for ruler, orchidometer, and ultrasonography measurements based on a longitudinal follow-up

  Koskela M; Virtanen HE; Rodprasert W; Jahnukainen K; Toppari J; Koskenniemi JJ
• Article: GENES CHROMOSOMES & CANCER. 2024;63(11):e70003

  Characterization of Pediatric Acute Myeloid Leukemia With t(7;12)(q36;p13).

  Östlund A; Waraky A; Staffas A; Sjögren H; De Moerloose B; Arad-Cohen N; Cheuk D; Navarro JMF; Jahnukainen K; Kaspers GJL; Kovalova Z; Pasauliene R; Saks K; Zeller B; Norén-Nyström U; Hasle H; Fogelstrand L; Abrahamsson J; Palmqvist L
• Article: REPRODUCTION AND FERTILITY. 2024;5(4):RAF-24-0032

  Factors influencing the timing of ovarian tissue cryopreservation in young girls

  Pampanini V; Sahlin L; Holopainen E; Taskinen M; Koskela M; Vettenranta K; Vettenranta J; Laine T; Anderson C; Jahnukainen K
• Article: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2024;(212)

  Z-Scores for Assessing Ovarian Reserve in Young Patients Undergoing Fertility Preservation

  Hassan J; Damdimopoulou P; Lahtinen A; Jahnukainen K; Knuus K; Acharya G; Bjorvang RD
• Doctoral thesis: 2024

  Towards elucidating the function of the oocyte Subcortical Maternal Complex: A multi-omic analysis of an Nlrp5-null murine model

  Nic Aodha L
• Article: HAEMATOLOGICA. 2024;109(9):2873-2883

  Management of hyperleukocytosis in pediatric acute myeloid leukemia using immediate chemotherapy without leukapheresis: results from the NOPHO-DBH AML 2012 protocol.

  Zeller B; Arad-Cohen N; Cheuk D; De Moerloose B; Navarro JMF; Hasle H; Jahnukainen K; Juul-Dam KL; Kaspers G; Kovalova Z; Jonsson OG; Lausen B; Munthe-Kaas M; Nystrom UN; Palle J; Pasauliene R; Pronk CJ; Saks K; Tierens A; Abrahamsson J
• Article: HUMAN REPRODUCTION OPEN. 2024;2024(3):hoae049

  Prior exposure to alkylating agents negatively impacts testicular organoid formation in cells obtained from childhood cancer patients

  Cui Y; Harteveld F; Omar HAMB; Yang Y; Bjarnason R; Romerius P; Sundin M; Nystrom UN; Langenskiold C; Vogt H; Henningsohn L; Frisk P; Vepsalainen K; Petersen C; Mitchell RT; Guo J; Alves-Lopes JP; Jahnukainen K; Stukenborg J-B
• Article: NATURE COMMUNICATIONS. 2024;15(1):6989

  In-depth analysis of transcriptomes in ovarian cortical follicles from children and adults reveals interfollicular heterogeneity

  Rooda I; Hassan J; Hao J; Wagner M; Moussaud-Lamodiere E; Jaager K; Otala M; Knuus K; Lindskog C; Papaikonomou K; Gidlof S; Langenskiold C; Vogt H; Frisk P; Malmros J; Tuuri T; Salumets A; Jahnukainen K; Velthut-Meikas A; Damdimopoulou P
• Review: HEMASPHERE. 2024;8(8):e145

  How to manage patients with germline DDX41 variants: Recommendations from the Nordic working group on germline predisposition for myeloid neoplasms.

  Baliakas P; Tesi B; Cammenga J; Stray-Pedersen A; Jahnukainen K; Andersen MK; Ågerstam H; Creignou M; Dybedal I; Raaschou-Jensen K; Grønbæk K; Kilpivaara O; Lindberg EH; Wartiovaara-Kautto U
• Review: CTS-CLINICAL AND TRANSLATIONAL SCIENCE. 2024;17(7):e13866

  Alkylating agents-induced gonadotoxicity in prepubertal males: Insights on the clinical and preclinical front

  Sriram S; Macedo T; Mavinkurve-Groothuis A; van de Wetering M; Looijenga LHJ
• Article: BRITISH JOURNAL OF HAEMATOLOGY. 2024;205(1):229-235

  Decreased spermatogonial numbers in boys with severe haematological diseases

  Lahtinen AK; Funke M; Krallmann C; Wyrwoll MJ; Jarisch A; Yang Y; Bjarnason R; Romerius P; Sundin M; Noren-Nystrom U; Langenskiold C; Cremers J-F; Kliesch S; Stukenborg J-B; Neuhaus N; Jahnukainen K
• Letter: AMERICAN JOURNAL OF HEMATOLOGY. 2024;99(7):1403-1406

  Comparison of outcomes of immunosuppressive therapy with rabbit versus horse antithymocyte globulin and cyclosporine a in children with acquired severe aplastic anemia.

  Yoshimi A; Noellke P; Starý J; Kállay K; Smith O; Locatelli F; Buechner J; Bodova I; Sevilla J; Schmugge M; Bierings M; Masmas T; Dworzak M; Labarque V; Pawelec K; Jahnukainen K; Polychronopoulou S; Kjollerstrom P; Kavcic M; Erlacher M; Niemeyer CM; Strahm B
• Article: JOURNAL OF CLINICAL ONCOLOGY. 2024;42(18):2174-2185

  Mitoxantrone Versus Liposomal Daunorubicin in Induction of Pediatric AML With Risk Stratification Based on Flow Cytometry Measurement of Residual Disease.

  Tierens A; Arad-Cohen N; Cheuk D; De Moerloose B; Fernandez Navarro JM; Hasle H; Jahnukainen K; Juul-Dam KL; Kaspers G; Kovalova Z; Lausen B; Norén-Nyström U; Palle J; Pasauliene R; Jan Pronk C; Saks K; Zeller B; Abrahamsson J
• Article: INTERNATIONAL JOURNAL OF CANCER. 2024;154(12):2121-2131

  Reproductive late effects and testosterone replacement therapy in male childhood cancer survivors: A population-based study (the Fex-Can study)

  Haavisto A; Lampic C; Wettergren L; Laehteenmaeki PM; Jahnukainen K
• Article: INTERNET INTERVENTIONS-THE APPLICATION OF INFORMATION TECHNOLOGY IN MENTAL AND BEHAVIOURAL HEALTH. 2024;36:100739

  Efficacy of a web-based psychoeducational intervention, Fex-can sex, for young adult childhood cancer survivors with sexual dysfunction: A randomized controlled trial

  Fagerkvist K; Jahnukainen K; Ljungman L; Lampic C; Wettergren L
• Article: HUMAN REPRODUCTION OPEN. 2024;2024(2):hoae010

  A 20-year overview of fertility preservation in boys: new insights gained through a comprehensive international survey

  Duffin K; Neuhaus N; Andersen CY; Barraud-Lange V; Braye A; Eguizabal C; Feraille A; Ginsberg JP; Gook D; Goossens E; Jahnukainen K; Jayasinghe Y; Keros V; Kliesch S; Lane S; Mulder CL; Orwig KE; van Pelt AMM; Poirot C; Rimmer MP; Rives N; Sadri-Ardekani H; Safrai M; Schlatt S; Stukenborg J-B; van de Wetering MD; Wyns C; Mitchell RT
• Article: NATURE PROTOCOLS. 2024;19(4):1149-1182

  Human primordial germ cell-like cells specified from resetting precursors develop in human hindgut organoids.

  Alves-Lopes JP; Wong FCK; Surani MA
• Article: BRITISH JOURNAL OF HAEMATOLOGY. 2024;204(2):595-605

  Biallelic inactivation of the NF1 tumour suppressor gene in juvenile myelomonocytic leukaemia: Genetic evidence of driver function and implications for diagnostic workup.

  Ramamoorthy S; Lebrecht D; Schanze D; Schanze I; Wieland I; Andrieux G; Metzger P; Hess M; Albert MH; Borkhardt A; Bresters D; Buechner J; Catala A; De Haas V; Dworzak M; Erlacher M; Hasle H; Jahnukainen K; Locatelli F; Masetti R; Stary J; Turkiewicz D; Vinci L; Wlodarski MW; Yoshimi A; Boerries M; Niemeyer CM; Zenker M; Flotho C
• Article: JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY. 2023;29(10):943-952

  A comparison of WPPSI-IV performance between Finland-Swedish minority children and the Scandinavian test norms: Findings from The FinSwed Study

  Salonen J; Slama S; Haavisto A; Rosenqvist J
• Article: CANCER. 2023;129(22):3633-3644

  Therapeutic exposures and pubertal testicular dysfunction are associated with adulthood milestones and paternity after childhood cancer

  Korhonen M; Tainio J; Koskela M; Madanat-Harjuoja L-M; Jahnukainen K
• Article: BLOOD ADVANCES. 2023;7(21):6532-6539

  Survival outcomes of children with relapsed or refractory myeloid leukemia associated with Down syndrome.

  Raghuram N; Hasegawa D; Nakashima K; Rahman S; Antoniou E; Skajaa T; Merli P; Verma A; Rabin KR; Aftandilian C; Kotecha RS; Cheuk D; Jahnukainen K; Kolenova A; Balwierz W; Norton A; O'Brien M; Cellot S; Chopek A; Arad-Cohen N; Goemans B; Rojas-Vasquez M; Ariffin H; Bartram J; Kolb EA; Locatelli F; Klusmann J-H; Hasle H; McGuire B; Hasnain A; Sung L; Hitzler J
• Article: REPRODUCTIVE BIOMEDICINE ONLINE. 2023;47(4):103287

  Reference standards for follicular density in ovarian cortex from birth to sexual maturity

  Hassan J; Knuus K; Lahtinen A; Rooda I; Otala M; Tuuri T; Gidlof S; Edlund E; Menezes J; Malmros J; Bystrom P; Sundin M; Langenskiold C; Vogt H; Frisk P; Petersen C; Damdimopoulou P; Jahnukainen K
• Article: SCANDINAVIAN JOURNAL OF PSYCHOLOGY. 2023;64(4):409-420

  WPPSI-IV and NEPSY-II performance in mono- and bilingual 5-6-year-old children: Findings from The FinSwed Study

  Korpinen E; Slama S; Rosenqvist J; Haavisto A
• Article: INTERNATIONAL JOURNAL OF CANCER. 2023;153(3):644-653

  Premature ovarian insufficiency and chance of pregnancy after childhood cancer: A population-based study (the Fex-Can study)

  Haavisto A; Wettergren L; Lampic C; Lahteenmaki PM; Jahnukainen K
• Article: CHILD NEUROPSYCHOLOGY. 2023;29(5):687-709

  Comparison of WPPSI-IV and WISC-V cognitive profiles in 6-7-year-old Finland-Swedish children - findings from the FinSwed study

  Salonen J; Slama S; Haavisto A; Rosenqvist J
• Article: ACTA PAEDIATRICA. 2023;112(7):1471-1477

  No impact of parental singing during the neonatal period on cognition in preterm-born children at 2-3 years

  Kostilainen K; Hugoson P; Haavisto A; Partanen E; Mikkola K; Huotilainen M; Pakarinen S; Furmark C; Aden U; Fellman V
• Article: BLOOD. 2023;141(23):2853-2866

  The clinical picture of ERCC6L2 disease: from bone marrow failure to acute leukemia

  Hakkarainen M; Kaaja I; Douglas SPM; Vulliamy T; Dokal I; Soulier J; Larcher L; de Latour RP; Leblanc T; de Fontbrune FS; Siitonen T; Lohi O; Hellstrom-Lindberg E; Barbany G; Tesi B; Shimamura A; Beier F; Jackson S; Kuperman AA; Zaccai TF; Tamary H; Mecucci C; Capolsini I; Jahnukainen K; Salmenniemi U; Niinimaki R; Varilo T; Kilpivaara O; Wartiovaara-Kautto U
• Article: LAKARTIDNINGEN. 2023;120:22141

  [Long-term follow up after childhood cancer - during childhood and adult life].

  Petersen C; Óskarsson T; Jarfelt M; Hjorth L
• Letter: BONE MARROW TRANSPLANTATION. 2023;58(5):607-609

  Second allogeneic stem cell transplantation can rescue a significant proportion of patients with JMML relapsing after first allograft.

  Vinci L; Flotho C; Noellke P; Lebrecht D; Masetti R; de Haas V; De Moerloose B; Dworzak M; Hasle H; Güngör T; Starý J; Turkiewicz D; Ussowicz M; de Heredia CD; Buechner J; Jahnukainen K; Kallay K; Bodova I; Smith OP; Zecca M; Bresters D; Lang P; Masmas TN; Meisel R; Pichler H; Erlacher M; Göhring G; Locatelli F; Strahm B; Niemeyer CM; Yoshimi A
• Article: BRITISH JOURNAL OF HAEMATOLOGY. 2023;201(4):757-765

  Characteristics and outcome of primary resistant disease in paediatric acute myeloid leukaemia.

  Karlsson L; Cheuk D; De Moerloose B; Hasle H; Jahnukainen K; Juul-Dam KL; Kaspers G; Kovalova Z; Lausen B; Nyström UN; Palle J; Pronk CJ; Saks K; Tierens A; Zeller B; Abrahamsson J
• Article: AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE. 2023;108(4):851-856

  The Effect of Blood Transfusion on the Survival of Children with Both Severe Anemia and Bacterial Meningitis.

  Pelkonen T; Roine I; Cruzeiro M; Jahnukainen K; Peltola H
• Article: BLOOD ADVANCES. 2023;7(6):1045-1055

  Hypodiploidy has unfavorable impact on survival in pediatric acute myeloid leukemia: an I-BFM Study Group collaboration.

  Hammer ASB; Juul-Dam KL; Sandahl JD; Abrahamsson J; Czogala M; Delabesse E; Haltrich I; Jahnukainen K; Kolb EA; Kovács G; Leverger G; Locatelli F; Masetti R; Noren-Nyström U; Raimondi SC; Rasche M; Reinhardt D; Taki T; Tomizawa D; Zeller B; Hasle H; Kjeldsen E
• Article: HUMAN REPRODUCTION. 2023;38(3):359-370

  Childhood cancer and hematological disorders negatively affect spermatogonial quantity at diagnosis: a retrospective study of a male fertility preservation cohort

  Masliukaite I; Ntemou E; Feijen EAM; van de Wetering M; Meissner A; Soufan AT; Repping S; Kremer LMC; Jahnukainen K; Goossens E; van Pelt AMM
• Article: LEUKEMIA. 2023;37(3):550-559

  Proteogenomic analysis of acute myeloid leukemia associates relapsed disease with reprogrammed energy metabolism both in adults and children

  Stratmann S; Vesterlund M; Umer HM; Eshtad S; Skaftason A; Herlin MK; Sundstrom C; Eriksson A; Hoglund M; Palle J; Abrahamsson J; Jahnukainen K; Munthe-Kaas MC; Zeller B; Tamm KP; Lindskog C; Cavelier L; Lehtio J; Holmfeldt L
• Article: CELL REPORTS. 2023;42(1):111907

  Specification of human germ cell fate with enhanced progression capability supported by hindgut organoids

  Alves-Lopes JP; Wong FCK; Tang WWC; Gruhn WH; Ramakrishna NB; Jowett GM; Jahnukainen K; Surani MA
• Article: SCIENCE ADVANCES. 2023;9(3):eade1257

  Epigenetic resetting in the human germ line entails histone modification remodeling

  Gruhn WH; Tang WWC; Dietmann S; Alves-Lopes JP; Penfold CA; Wong FCK; Ramakrishna NB; Surani MA
• Article: BONE MARROW TRANSPLANTATION. 2023;58(1):39-45

  Clinically relevant germline variants in allogeneic hematopoietic stem cell transplant recipients

  Lahtinen AK; Koski J; Ritari J; Hyvarinen K; Koskela S; Partanen J; Vettenranta K; Koskenvuo M; Niittyvuopio R; Salmenniemi U; Itala-Remes M; Jahnukainen K; Kilpivaara O; Wartiovaara-Kautto U
• Review: EXPERT REVIEW OF ANTICANCER THERAPY. 2022;22(11):1183-1196

  Supportive care in pediatric acute myeloid leukemia:Expert-based recommendations of the NOPHO-DB-SHIP consortium.

  Arad-Cohen N; Zeller B; Abrahamsson J; Fernandez Navarro JM; Cheuk D; Palmu S; Costa V; De Moerloose B; Hasle H; Jahnukainen K; Pronk CJ; Gísli Jónsson Ó; Kovalova Z; Lausen B; Munthe-Kaas M; Noren-Nyström U; Palle J; Pasauliene R; Saks K; Kaspers GJ
• Review: TRANSPLANTATION AND CELLULAR THERAPY. 2022;28(8):503.e1-503.e15

  Male Gonadal Function After Pediatric Hematopoietic Stem Cell Transplantation: A Systematic Review

  Mathiesen S; Andres-Jensen L; Nielsen MM; Sorensen K; Ifversen M; Jahnukainen K; Juul A; Mueller K
• Article: PEDIATRIC INFECTIOUS DISEASE JOURNAL. 2022;41(8):e335-e338

  Bacterial Meningitis in Children With Sickle Cell Disease in Angola.

  Pelkonen T; Roine I; Bernardino L; Jahnukainen K; Peltola H
• Article: NATURE. 2022;607(7919):540-547

  Single-cell roadmap of human gonadal development

  Garcia-Alonso L; Lorenzi V; Mazzeo CI; Alves-Lopes JP; Roberts K; Sancho-Serra C; Engelbert J; Mareckova M; Gruhn WH; Botting RA; Li T; Crespo B; van Dongen S; Kiselev VY; Prigmore E; Herbert M; Moffett A; Chedotal A; Bayraktar OA; Surani A; Haniffa M; Vento-Tormo R
• Article: CANCERS. 2022;14(14):3310

  Physical Fitness and Frailty in Males after Allogeneic Hematopoietic Stem Cell Transplantation in Childhood: A Long-Term Follow-Up Study

  Suominen A; Haavisto A; Mathiesen S; Mejdahl Nielsen M; Lahteenmaki PM; Sorensen K; Ifversen M; Molgaard C; Juul A; Muller K; Jahnukainen K
• Article: SCIENTIFIC REPORTS. 2022;12(1):10670

  Enrichment of cancer-predisposing germline variants in adult and pediatric patients with acute lymphoblastic leukemia

  Douglas SPM; Lahtinen AK; Koski JR; Leimi L; Keranen MAI; Koskenvuo M; Heckman CA; Jahnukainen K; Pitkanen E; Wartiovaara-Kautto U; Kilpivaara O
• Article: BONE MARROW TRANSPLANTATION. 2022;57(5):705-711

  Early vascular toxicity after pediatric allogeneic hematopoietic stem cell transplantation

  Leimi L; Jahnukainen K; Olkinuora H; Meri S; Vettenranta K
• Article: BMJ PAEDIATRICS OPEN. 2022;6(1):e001361

  Latent class growth analysis identified different trajectories in cognitive development of extremely low birthweight children

  Haavisto A; Klenberg L; Tommiska V; Lano A; Mikkola K; Fellman V
• Letter: HAEMATOLOGICA. 2022;107(4):975-979

  Early testicular maturation is sensitive to depletion of spermatogonial pool in sickle cell disease

  Benninghoven-Frey KM; Neuhaus N; Lahtinen AK; Krallmann C; Portela JMD; Jarisch A; Nordhoff V; Soave A; Omar HAMB; Sundin M; Langenskiold C; Kliesch S; Stukenborg J-B; Jahnukainen K
• Article: BMJ OPEN. 2022;12(3):e057285

  Prevalence and significance of anaemia in childhood bacterial meningitis: a secondary analysis of prospectively collected data from clinical trials in Finland, Latin America and Angola.

  Pelkonen T; Roine I; Kallio M; Jahnukainen K; Peltola H
• Article: CANCERS. 2022;14(2):399

  Effect of Previous Alkylating Agent Exposure on Follicle Numbers in Cryopreserved Prepubertal and Young Adult Ovarian Tissue after Long-Term Xenografting

  Nurmio M; Asadi-Azarbaijani B; Hou M; Kivioe R; Toppari J; Tinkanen H; Laine T; Oskam IC; Jahnukainen K
• Article: BLOOD ADVANCES. 2022;6(1):152-164

  Transcriptomic analysis reveals proinflammatory signatures associated with acute myeloid leukemia progression

  Stratmann S; Yones SA; Garbulowski M; Sun J; Skaftason A; Mayrhofer M; Norgren N; Herlin MK; Sundstrom C; Eriksson A; Hoglund M; Palle J; Abrahamsson J; Jahnukainen K; Munthe-Kaas MC; Zeller B; Tamm KP; Cavelier L; Komorowski J; Holmfeldt L
• Article: BLOOD. 2021;138(23):2441-2445

  Association of unbalanced translocation der(1;7) with germline GATA2 mutations

  Kozyra EJ; Goehring G; Hickstein DD; Calvo KR; DiNardo CD; Dworzak M; de Haas V; Stary J; Hasle H; Shimamura A; Fleming MD; Inaba H; Lewis S; Hsu AP; Holland SM; Arnold DE; Mecucci C; Keel SB; Bertuch AA; Tawana K; Barzilai S; Hirabayashi S; Onozawa M; Lei S; Alaiz H; Andrikovics H; Betts D; Beverloo BH; Buechner J; Cermak M; Cervera J; Haus O; Jahnukainen K; Manola KN; Nebral K; Pasquali F; Tchinda J; Turkiewicz D; Van Roy N; Zemanova Z; Pastor VB; Strahm B; Noellke P; Niemeyer CM; Schlegelberger B; Yoshimi A; Wlodarski MW
• Corrigendum: NATURE MEDICINE. 2021;27(12):2248

  Publisher Correction: Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes.

  Sahoo SS; Pastor VB; Goodings C; Voss RK; Kozyra EJ; Szvetnik A; Noellke P; Dworzak M; Starý J; Locatelli F; Masetti R; Schmugge M; De Moerloose B; Catala A; Kállay K; Turkiewicz D; Hasle H; Buechner J; Jahnukainen K; Ussowicz M; Polychronopoulou S; Smith OP; Fabri O; Barzilai S; de Haas V; Baumann I; Schwarz-Furlan S; European Working Group of MDS in Children (EWOG-MD; Niewisch MR; Sauer MG; Burkhardt B; Lang P; Bader P; Beier R; Müller I; Albert MH; Meisel R; Schulz A; Cario G; Panda PK; Wehrle J; Hirabayashi S; Derecka M; Durruthy-Durruthy R; Göhring G; Yoshimi-Noellke A; Ku M; Lebrecht D; Erlacher M; Flotho C; Strahm B; Niemeyer CM; Wlodarski MW
• Article: INTERNATIONAL JOURNAL OF CANCER. 2021;149(11):1863-1876

  Skeletal adverse events in childhood cancer survivors: An Adult Life after Childhood Cancer in Scandinavia cohort study

  Oskarsson T; Duun-Henriksen AK; Bautz A; Montgomery S; Harila-Saari A; Petersen C; Niinimaki R; Madanat-Harjuoja L; Tryggvadottir L; Holmqvist AS; Hasle H; Heyman M; Winther JF
• Article: FAMILIAL CANCER. 2021;20(4):305-316

  Current recommendations for clinical surveillance and genetic testing in rhabdoid tumor predisposition: a report from the SIOPE Host Genome Working Group

  Fruhwald MC; Nemes K; Boztug H; Cornips MCA; Evans DG; Farah R; Glentis S; Jorgensen M; Katsibardi K; Hirsch S; Jahnukainen K; Kventsel I; Kerl K; Kratz CP; Pajtler KW; Kordes U; Ridola V; Stutz E; Bourdeaut F
• Article: NATURE MEDICINE. 2021;27(10):1806-1817

  Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes.

  Sahoo SS; Pastor VB; Goodings C; Voss RK; Kozyra EJ; Szvetnik A; Noellke P; Dworzak M; Starý J; Locatelli F; Masetti R; Schmugge M; De Moerloose B; Catala A; Kállay K; Turkiewicz D; Hasle H; Buechner J; Jahnukainen K; Ussowicz M; Polychronopoulou S; Smith OP; Fabri O; Barzilai S; de Haas V; Baumann I; Schwarz-Furlan S; European Working Group of MDS in Children (EWOG-MD; Niewisch MR; Sauer MG; Burkhardt B; Lang P; Bader P; Beier R; Müller I; Albert MH; Meisel R; Schulz A; Cario G; Panda PK; Wehrle J; Hirabayashi S; Derecka M; Durruthy-Durruthy R; Göhring G; Yoshimi-Noellke A; Ku M; Lebrecht D; Erlacher M; Flotho C; Strahm B; Niemeyer CM; Wlodarski MW
• Article: BMC BIOLOGY. 2021;19(1):212

  Self-organising human gonads generated by a Matrigel-based gradient system

  Oliver E; Alves-Lopes JP; Harteveld F; Mitchell RT; Akesson E; Soder O; Stukenborg J-B
• Article: TRANSPLANTATION AND CELLULAR THERAPY. 2021;27(9):778.e1-778.e8

  Metabolic Syndrome in Male Survivors of Pediatric Allogeneic Hematopoietic Stem Cell Transplantation: Impact of Total Body Irradiation, Low-Grade Inflammation, and Hypogonadism

  Muhic E; Mathiesen S; Nielsen MM; Suominen A; Sorensen K; Ifversen M; Nolsoe RL; Pedersen KM; Lahteenmaki P; Nordestgaard BG; Juul A; Jahnukainen K; Muller K
• Article: FERTILITY AND STERILITY. 2021;116(3):713-720

  Z-scores for comparative analyses of spermatogonial numbers throughout human development

  Funke M; Yang Y; Lahtinen A; Benninghoven-Frey K; Kliesch S; Neuhaus N; Stukenborg J-B; Jahnukainen K
• Article: EUROPEAN JOURNAL OF CANCER. 2021;154:147-156

  Sexual dysfunction in young adult survivors of childhood cancer- A population-based study

  Hoven E; Fagerkvist K; Jahnukainen K; Ljungman L; Lahteenmaki PM; Axelsson O; Lampic C; Wettergren L
• Article: GENES. 2021;12(6):895

  DNA Methylation Signatures Predict Cytogenetic Subtype and Outcome in Pediatric Acute Myeloid Leukemia (AML).

  Krali O; Palle J; Bäcklin CL; Abrahamsson J; Norén-Nyström U; Hasle H; Jahnukainen K; Jónsson ÓG; Hovland R; Lausen B; Larsson R; Palmqvist L; Staffas A; Zeller B; Nordlund J
• Letter: AMERICAN JOURNAL OF HEMATOLOGY. 2021;96(3):E74-E77

  Hospitalizations in long-term survivors of childhood AML treated with allogeneic HCT-An Adult Life after Childhood Cancer in Scandinavia (ALiCCS) study

  Wilhelmsson M; Jahnukainen K; Winiarski J; Abrahamsson J; Bautz A; Gudmundsdottir T; Madanat-Harjuoja L-M; Holmqvist AS; Winther JF; Hasle H
• Article: BLOOD ADVANCES. 2021;5(3):900-912

  Genomic characterization of relapsed acute myeloid leukemia reveals novel putative therapeutic targets

  Stratmann S; Yones SA; Mayrhofer M; Norgren N; Skaftason A; Sun J; Smolinska K; Komorowski J; Herlin MK; Sundstrom C; Eriksson A; Hoglund M; Palle J; Abrahamsson J; Jahnukainen K; Munthe-Kaas MC; Zeller B; Tamm KP; Cavelier L; Holmfeldt L
• Article: LANCET ONCOLOGY. 2021;22(2):e57-e67

  Fertility preservation for male patients with childhood, adolescent, and young adult cancer: recommendations from the PanCareLIFE Consortium and the International Late Effects of Childhood Cancer Guideline Harmonization Group.

  Mulder RL; Font-Gonzalez A; Green DM; Loeffen EAH; Hudson MM; Loonen J; Yu R; Ginsberg JP; Mitchell RT; Byrne J; Skinner R; Anazodo A; Constine LS; de Vries A; Jahnukainen K; Lorenzo A; Meissner A; Nahata L; Dinkelman-Smit M; Tournaye H; Haupt R; van den Heuvel-Eibrink MM; van Santen HM; van Pelt AMM; Dirksen U; den Hartogh J; van Dulmen-den Broeder E; Wallace WH; Levine J; Tissing WJE; Kremer LCM; Kenney LB; van de Wetering MD; PanCareLIFE Consortium
• Article: BONE MARROW TRANSPLANTATION. 2021;56(2):457-460

  Altered body composition in male long-term survivors of paediatric allogeneic haematopoietic stem cell transplantation: impact of conditioning regimen, chronic graft-versus-host disease and hypogonadism

  Mejdahl Nielsen M; Mathiesen S; Suominen A; Sorensen K; Ifversen M; Molgaard C; Lahteenmaki PM; Juul A; Jahnukainen K; Mueller K
• Article: CELLS. 2021;10(2):241

  Spermatogonia Loss Correlates with LAMA 1 Expression in Human Prepubertal Testes Stored for Fertility Preservation

  Kurek M; Akesson E; Yoshihara M; Oliver E; Cui Y; Becker M; Alves-Lopes JP; Bjarnason R; Romerius P; Sundin M; Noren Nystrom U; Langenskiold C; Vogt H; Henningsohn L; Petersen C; Soder O; Guo J; Mitchell RT; Jahnukainen K; Stukenborg J-B
• Article: FRONTIERS IN CARDIOVASCULAR MEDICINE. 2021;8:715953

  Cardiac Function After Cardiotoxic Treatments for Childhood Cancer-Left Ventricular Longitudinal Strain in Screening.

  Niemelä J; Ylänen K; Suominen A; Pushparajah K; Mathur S; Sarkola T; Jahnukainen K; Eerola A; Poutanen T; Vettenranta K; Ojala T
• Article: BMC MEDICINE. 2020;18(1):374

  Cisplatin and carboplatin result in similar gonadotoxicity in immature human testis with implications for fertility preservation in childhood cancer

  Tharmalingam MD; Matilionyte G; Wallace WHB; Stukenborg J-B; Jahnukainen K; Oliver E; Goriely A; Lane S; Guo J; Cairns B; Jorgensen A; Allen CM; Lopes F; Anderson RA; Spears N; Mitchell RT
• Article: JOURNAL OF SEXUAL MEDICINE. 2020;17(10):2104-2107

  Male Sexual Function After Pediatric Kidney Transplantation-A Cross-sectional Nationwide Study.

  Tainio J; Jahnukainen T; Jalanko H; Jahnukainen K
• Article: TRANSPLANTATION AND CELLULAR THERAPY. 2020;26(9):1635-1645

  Male Gonadal Function after Allogeneic Hematopoietic Stem Cell Transplantation in Childhood: A Cross-Sectional, Population-Based Study

  Mathiesen S; Sorensen K; Nielsen MM; Suominen A; Ifversen M; Grell K; Lahteenmaki P; Frederiksen H; Juul A; Mueller K; Jahnukainen K
• Article: PEDIATRIC NEPHROLOGY. 2020;35(9):1719-1728

  Cancer morbidity and mortality after pediatric solid organ transplantation-a nationwide register study.

  Endén K; Tainio J; Nikkilä A; Helanterä I; Nordin A; Pakarinen MP; Jalanko H; Jahnukainen K; Jahnukainen T
• Article: PEDIATRIC BLOOD & CANCER. 2020;67(8):e28209

  Long-term renal prognosis and risk for hypertension after myeloablative therapies in survivors of childhood high-risk neuroblastoma: A nationwide study

  Suominen A; Jahnukainen T; Ojala TH; Sarkola T; Turanlahti M; Saarinen-Pihkala UM; Jahnukainen K
• Article: JOURNAL OF CLINICAL MEDICINE. 2020;9(7):E2208-2208

  Early Arterial Intimal Thickening and Plaque Is Related with Treatment Regime and Cardiovascular Disease Risk Factors in Young Adults Following Childhood Hematopoietic Stem Cell Transplantation

  Sundholm JKM; Suominen A; Sarkola T; Jahnukainen K
• Study protocol: MEDICINE. 2020;99(28):e19919

  Study protocol for the Fex-Can Childhood project An observational study and a randomized controlled trial focusing on sexual dysfunction and fertility-related distress in young adult survivors of childhood cancer

  Ljungman L; Anandavadivelan P; Jahnukainen K; Lampic C; Wettergren L
• Article: CANCERS. 2020;12(7):E1786-1786

  Male Sexual Function after Allogeneic Hematopoietic Stem Cell Transplantation in Childhood: A Multicenter Study

  Haavisto A; Mathiesen S; Suominen A; Lahteenmaki P; Sorensen K; Ifversen M; Juul A; Nielsen MM; Muller K; Jahnukainen K
• Article: BRITISH JOURNAL OF HAEMATOLOGY. 2020;190(2):198-208

  Measurable residual disease assessment by qPCR in peripheral blood is an informative tool for disease surveillance in childhood acute myeloid leukaemia.

  Juul-Dam KL; Ommen HB; Nyvold CG; Walter C; Vålerhaugen H; Kairisto V; Abrahamsson J; Alm SJ; Jahnukainen K; Lausen B; Reinhardt D; Zeller B; von Neuhoff N; Fogelstrand L; Hasle H
• Letter: HUMAN REPRODUCTION. 2020;35(5):1249-1251

  Reply: Impact of first-line cancer treatment on follicle quality in cryopreserved ovarian samples

  Pampanini V; Wagner M; Asadi-Azarbaijani B; Oskam IC; Sheikhi M; Sjodin MOD; Lindberg J; Hovatta O; Sahlin L; Bjorvang RD; Otala M; Damdimopoulou P; Jahnukainen K
• Article: JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY. 2020;146(4):953-960

  Synovial sarcoma disease characteristics and primary tumor sites differ between patient age groups: a report of the Cooperative Weichteilsarkom Studiengruppe (CWS).

  Scheer M; Blank B; Bauer S; Vokuhl C; Stegmaier S; Feuchtgruber S; Henssen A; Sparber-Sauer M; Eggert A; Handgretinger R; Pekrun A; Rossig C; Rutkowski S; Schlegel P-G; Schrappe M; Simon T; Kazanowska B; Niggli F; Ladenstein R; Ljungman G; Jahnukainen K; Fuchs J; Bielack SS; Koscielniak E; Klingebiel T; Cooperative Weichteilsarkom Studiengruppe [CWS]
• Article: HUMAN REPRODUCTION OPEN. 2020;2020(3):hoaa016

  Fertility preservation in boys: recent developments and new insights

  Goossens E; Jahnukainen K; Mitchell RT; van Pelt AMM; Pennings G; Rives N; Poels J; Wyns C; Lane S; Rodriguez-Wallberg KA; Rives A; Valli-Pulaski H; Steimer S; Kliesch S; Braye A; Andres MM; Medrano J; Ramos L; Kristensen SG; Andersen CY; Bjarnason R; Orwig KE; Neuhaus N; Stukenborg JB
• Review: HORMONE RESEARCH IN PAEDIATRICS. 2020;93(11-12):599-608

  Fertility Preservation for Prepubertal Patients at Risk of Infertility: Present Status and Future Perspectives

  Pampanini V; Hassan J; Oliver E; Stukenborg J-B; Damdimopoulou P; Jahnukainen K
• Review: HEMASPHERE. 2019;3(6):e321

  Nordic Guidelines for Germline Predisposition to Myeloid Neoplasms in Adults: Recommendations for Genetic Diagnosis, Clinical Management and Follow-up.

  Baliakas P; Tesi B; Wartiovaara-Kautto U; Stray-Pedersen A; Friis LS; Dybedal I; Hovland R; Jahnukainen K; Raaschou-Jensen K; Ljungman P; Rustad CF; Lautrup CK; Kilpivaara O; Kittang AO; Grønbæk K; Cammenga J; Hellström-Lindberg E; Andersen MK
• Article: PEDIATRIC TRANSPLANTATION. 2019;23(7):e13550

  Telomere length regulators are activated in young men after pediatric kidney transplantation compared to healthy controls and survivors of childhood cancer-A cross-sectional study

  Enden K; Tainio J; Hou M; Suominen A; Pakarinen M; Huang T; Soder O; Jalanko H; Jahnukainen K; Jahnukainen T
• Article: HUMAN REPRODUCTION. 2019;34(9):1674-1685

  Impact of first-line cancer treatment on the follicle quality in cryopreserved ovarian samples from girls and young women

  Pampanini V; Wagner M; Asadi-Azarbaijani B; Oskam IC; Sheikhi M; Sjodin MOD; Lindberg J; Hovatta O; Sahlin L; Bjorvang RD; Otala M; Damdimopoulou P; Jahnukainen K
• Article: FRONTIERS IN ENDOCRINOLOGY. 2019;10:555

  Gonadal Failure Is Common in Long-Term Survivors of Childhood High-Risk Neuroblastoma Treated With High-Dose Chemotherapy and Autologous Stem Cell Rescue

  Utriainen P; Suominen A; Makitie O; Jahnukainen K
• Article: REPRODUCTIVE BIOLOGY. 2019;19(2):133-138

  Imatinib mesylate does not counteract ovarian tissue fibrosis in postnatal rat ovary.

  Asadi-Azarbaijani B; Braber S; van Duursen M; Jahnukainen K; Santos R; Oskam I
• Article: LEUKEMIA & LYMPHOMA. 2019;60(6):1469-1475

  Asparaginase treatment in infants with acute lymphoblastic leukemia; pharmacokinetics and asparaginase hypersensitivity in Interfant-06

  Albertsen BK; Harila-Saari A; Jahnukainen K; Lahteenmaki P; Riikonen P; Mottonen M; Lausen B
• Letter: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2019;98(5):679-680

  National guidelines and multilingual age-adapted patient brochures and videos as decision aids for fertility preservation (FP) of children and teenagers with cancer-A multidisciplinary effort to improve children's information and access to FP in Sweden

  Rodriguez-Wallberg KA; Borgstrom B; Petersen C; Thurin-Kjellberg A; Morse H; Giwercman A; Jarfelt M
• Article: BONE MARROW TRANSPLANTATION. 2019;54(5):726-736

  Long-term health outcomes in survivors of childhood AML treated with allogeneic HSCT: a NOPHO-AML Study

  Wilhelmsson M; Glosli H; Ifversen M; Abrahamsson J; Winiarski J; Jahnukainen K; Hasle H
• Article: EARLY HUMAN DEVELOPMENT. 2019;132:13-17

  Postnatal N‑acetylcysteine does not provide neuroprotection in extremely low birth weight infants: A follow-up of a randomized controlled trial.

  Kiuru A; Ahola T; Klenberg L; Tommiska V; Lano A; Kleemola P; Haavisto A; Fellman V
• Article: CANCER MEDICINE. 2019;8(2):527-542

  Desmoplastic small round cell tumors: Multimodality treatment and new risk factors.

  Scheer M; Vokuhl C; Blank B; Hallmen E; von Kalle T; Münter M; Wessalowski R; Hartwig M; Sparber-Sauer M; Schlegel P-G; Kramm CM; Kontny U; Spriewald B; Kegel T; Bauer S; Kazanowska B; Niggli F; Ladenstein R; Ljungman G; Jahnukainen K; Fuchs J; Bielack SS; Klingebiel T; Koscielniak E; Cooperative Weichteilsarkom Studiengruppe [CWS]
• Article: REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY. 2019;17(1):10

  Impact of uteroplacental insufficiency on ovarian follicular pool in the rat

  Pampanini V; Jahnukainen K; Sahlin L; Germani D; Puglianiello A; Cianfarani S; Soder O
• Article: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY. 2019;41(1):e12-e17

  Hearing Status in Survivors of Childhood Acute Myeloid Leukemia Treated With Chemotherapy Only: A NOPHO-AML Study

  Skou A-S; Olsen SO; Nielsen LH; Glosli H; Jahnukainen K; Jarfelt M; Jonmundsson GK; Malmros J; Nysom K; Hasle H; Rosthoj S; Rechnitzer C; Carlsen N; Wehner P; Hovi L; Perkkio M; Arola M; Harila-Saari A; Wojcik DM; Lund B; Stensvold E; Behrendtz M; Hjorth L; Hjalmars U; Arvidson J; Rinaldo C
• Article: NEURO-ONCOLOGY. 2019;21(1):125-136

  Neurologic disorders in 4858 survivors of central nervous system tumors in childhood-an Adult Life after Childhood Cancer in Scandinavia (ALiCCS) study.

  Kenborg L; Winther JF; Linnet KM; Krøyer A; Albieri V; Holmqvist AS; Tryggvadottir L; Madanat-Harjuoja LM; Stovall M; Hasle H; Olsen JH; ALiCCS study group
• Article: BRITISH JOURNAL OF HAEMATOLOGY. 2018;183(4):618-628

  Complex and monosomal karyotype are distinct cytogenetic entities with an adverse prognostic impact in paediatric acute myeloid leukaemia. A NOPHO-DBH-AML study.

  Bager N; Juul-Dam KL; Sandahl JD; Abrahamsson J; Beverloo B; de Bont ESJM; Ha S-Y; Jahnukainen K; Jónsson ÓG; Kaspers GL; Kovalova Z; Lausen B; De Moerloose B; Noren-Nyström U; Palle J; Saks K; Zeller B; Kjeldsen E; Hasle H
• Article: HUMAN REPRODUCTION. 2018;33(9):1677-1683

  Spermatogonial quantity in human prepubertal testicular tissue collected for fertility preservation prior to potentially sterilizing therapy

  Stukenborg J-B; Alves-Lopes JP; Kurek M; Albalushi H; Reda A; Keros V; Tohonen V; Bjarnason R; Romerius P; Sundin M; Nystrom UN; Langenskiold C; Vogt H; Henningsohn L; Mitchell RT; Soder O; Petersen C; Jahnukainen K
• Article: ORPHANET JOURNAL OF RARE DISEASES. 2018;13(1):139

  Diagnostics of rare disorders: whole-exome sequencing deciphering locus heterogeneity in telomere biology disorders

  Trotta L; Norberg A; Taskinen M; Beziat V; Degerman S; Wartiovaara-Kautto U; Valimaa H; Jahnukainen K; Casanova J-L; Seppanen M; Saarela J; Koskenvuo M; Martelius T
• Doctoral thesis: 2018

  Novel culture systems to model testicular function and organization

  Lopes JP
• Review: GENES CHROMOSOMES & CANCER. 2018;57(7):359-365

  Acute myeloid leukemia (AML) with t(7;12)(q36;p13) is associated with infancy and trisomy 19: Data from Nordic Society for Pediatric Hematology and Oncology (NOPHO-AML) and review of the literature.

  Espersen ADL; Noren-Nyström U; Abrahamsson J; Ha S-Y; Pronk CJ; Jahnukainen K; Jónsson ÓG; Lausen B; Palle J; Zeller B; Palmqvist L; Hasle H
• Review: HUMAN REPRODUCTION UPDATE. 2018;24(2):176-191

  Testicular organoids: a new model to study the testicular microenvironment in vitro?

  Alves-Lopes JP; Stukenborg J-B
• Review: ENDOCRINE CONNECTIONS. 2018;7(2):R69-R87

  Cancer treatment in childhood and testicular function: the importance of the somatic environment

  Stukenborg J-B; Jahnukainen K; Hutka M; Mitchell RT
• Article: TRANSPLANT INTERNATIONAL. 2018;31(2):157-164

  Lower quality of life in young men after pediatric kidney transplantation when compared to healthy controls and survivors of childhood leukemia-a cross-sectional study.

  Endén K; Tainio J; Jalanko H; Jahnukainen K; Jahnukainen T
• Article: NATURE PROTOCOLS. 2018;13(2):248-259

  Use of a three-layer gradient system of cells for rat testicular organoid generation

  Alves-Lopes JP; Soder O; Stukenborg J-B
• Article: PEDIATRIC BLOOD & CANCER. 2017;64(12)

  Extramedullary leukemia in children with acute myeloid leukemia: A population-based cohort study from the Nordic Society of Pediatric Hematology and Oncology (NOPHO).

  Støve HK; Sandahl JD; Abrahamsson J; Asdahl PH; Forestier E; Ha S-Y; Jahnukainen K; Jónsson ÓG; Lausen B; Palle J; Zeller B; Hasle H
• Article: PEDIATRIC BLOOD & CANCER. 2017;64(12)

  Presenting features and imaging in childhood acute myeloid leukemia with central nervous system involvement

  Ranta S; Palomaki M; Levinsen M; Taskinen M; Abrahamsson J; Hasle H; Jahnukainen K; Heyman M; Harila-Saari A
• Article: BONE MARROW TRANSPLANTATION. 2017;52(10):1406-1415

  Fertility preservation issues in pediatric hematopoietic stem cell transplantation: practical approaches from the consensus of the Pediatric Diseases Working Party of the EBMT and the International BFM Study Group.

  Balduzzi A; Dalle J-H; Jahnukainen K; von Wolff M; Lucchini G; Ifversen M; Macklon KT; Poirot C; Diesch T; Jarisch A; Bresters D; Yaniv I; Gibson B; Willasch AM; Fadini R; Ferrari L; Lawitschka A; Ahler A; Sänger N; Corbacioglu S; Ansari M; Moffat R; Dalissier A; Beohou E; Sedlacek P; Lankester A; De Heredia Rubio CD; Vettenranta K; Wachowiak J; Yesilipek A; Trigoso E; Klingebiel T; Peters C; Bader P
• Article: BRITISH JOURNAL OF HAEMATOLOGY. 2017;178(3):448-456

  Hyperleucocytosis in paediatric acute myeloid leukaemia - the challenge of white blood cell counts above 200 × 109 /l. The NOPHO experience 1984-2014.

  Zeller B; Glosli H; Forestier E; Ha S-Y; Jahnukainen K; Jónsson ÓG; Lausen B; Palle J; Hasle H; Abrahamsson J; NOPHO AML working group
• Article: BRITISH JOURNAL OF HAEMATOLOGY. 2017;178(4):592-602

  Outcome after intensive reinduction therapy and allogeneic stem cell transplant in paediatric relapsed acute myeloid leukaemia.

  Karlsson L; Forestier E; Hasle H; Jahnukainen K; Jónsson ÓG; Lausen B; Norén Nyström U; Palle J; Tierens A; Zeller B; Abrahamsson J
• Conference publication: HUMAN REPRODUCTION. 2017;32:8

  Gradient system for testicular organoids generation - a novel system to model germ to somatic cell association in vitro

  Lopes JPA; Soder O; Stukenborg JB
• Article: BONE MARROW TRANSPLANTATION. 2017;52(7):1029-1035

  State-of-the-art fertility preservation in children and adolescents undergoing haematopoietic stem cell transplantation: a report on the expert meeting of the Paediatric Diseases Working Party (PDWP) of the European Society for Blood and Marrow Transplantation (EBMT) in Baden, Austria, 29-30 September 2015

  Dalle J-H; Lucchini G; Balduzzi A; Ifversen M; Jahnukainen K; Macklon KT; Ahler A; Jarisch A; Ansari M; Beohou E; Bresters D; Corbacioglu S; Dalissier A; de Heredia Rubio CD; Diesch T; Gibson B; Klingebiel T; Lankester A; Lawitschka A; Moffat R; Peters C; Poirot C; Saenger N; Sedlacek P; Trigoso E; Vettenranta K; Wachowiak J; Willasch A; von Wolff M; Yaniv I; Yesilipek A; Bader P
• Article: BIOMATERIALS. 2017;130:76-89

  Testicular organoid generation by a novel in vitro three-layer gradient system

  Alves-Lopes JP; Soder O; Stukenborg J-B
• Letter: LEUKEMIA. 2017;31(6):1460-1463

  Decreased spermatogonial quantity in prepubertal boys with leukaemia treated with alkylating agents

  Poganitsch-Korhonen M; Masliukaite I; Nurmio M; Lahteenmaki P; van Wely M; van Pelt AMM; Jahnukainen K; Stukenborg J-B
• Article: BONE MARROW TRANSPLANTATION. 2017;52(5):711-716

  Skeletal outcome in long-term survivors of childhood high-risk neuroblastoma treated with high-dose therapy and autologous stem cell rescue

  Utriainen P; Vatanen A; Toiviainen-Salo S; Saarinen-Pihkala U; Makitie O; Jahnukainen K
• Article: BONE MARROW TRANSPLANTATION. 2017;52(4):600-605

  Clinical and biological markers of premature aging after autologous SCT in childhood cancer

  Vatanen A; Hou M; Huang T; Soder O; Jahnukainen T; Kurimo M; Ojala TH; Sarkola T; Turanlahti M; Saarinen-Pihkala UM; Jahnukainen K
• Article: REPRODUCTIVE BIOLOGY. 2017;17(1):25-33

  Developmental effects of imatinib mesylate on follicle assembly and early activation of primordial follicle pool in postnatal rat ovary

  Asadi-Azarbaijani B; Santos RR; Jahnukainen K; Braber S; van Duursen MBM; Toppari J; Saugstad OD; Nurmio M; Oskam IC
• Review: LANCET ONCOLOGY. 2017;18(2):e75-e90

  Recommendations for gonadotoxicity surveillance in male childhood, adolescent, and young adult cancer survivors: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group in collaboration with the PanCareSurFup Consortium

  Skinner R; Mulder RL; Kremer LC; Hudson MM; Constine LS; Bardi E; Boekhout A; Borgmann-Staudt A; Brown MC; Cohn R; Dirksen U; Giwercman A; Ishiguro H; Jahnukainen K; Kenney LB; Loonen JJ; Meacham L; Neggers S; Nussey S; Petersen C; Shnorhavorian M; van den Heuvel-Eibrink MM; van Santen HM; Wallace WHB; Green DM
• Article: STEM CELL REPORTS. 2017;8(1):30-38

  Primary Human Testicular Cells Self-Organize into Organoids with Testicular Properties

  Baert Y; De Kock J; Alves-Lopes JP; Soder O; Stukenborg J-B; Goossens E
• Review: FERTILITY AND STERILITY. 2016;106(7):1652-1657.e2

  Establishing reference values for age-related spermatogonial quantity in prepubertal human testes: a systematic review and meta-analysis

  Masliukaite I; Hagen JM; Jahnukainen K; Stukenborg J-B; Repping S; van der Veen F; van Wely M; van Pelt AMM
• Article: GENES CHROMOSOMES & CANCER. 2016;55(9):719-726

  Trisomy 8 in pediatric acute myeloid leukemia: A NOPHO-AML study.

  Laursen ACL; Sandahl JD; Kjeldsen E; Abrahamsson J; Asdahl P; Ha S-Y; Heldrup J; Jahnukainen K; Jónsson ÓG; Lausen B; Palle J; Zeller B; Forestier E; Hasle H
• Article: BRITISH JOURNAL OF HAEMATOLOGY. 2016;174(4):600-609

  Residual disease detected by flow cytometry is an independent predictor of survival in childhood acute myeloid leukaemia; results of the NOPHO-AML 2004 study

  Tierens A; Bjorklund E; Siitonen S; Marquart HV; Wulff-Juergensen G; Pelliniemi T-T; Forestier E; Hasle H; Jahnukainen K; Lausen B; Jonsson OG; Palle J; Zeller B; Fogelstrand L; Abrahamsson J
• Article: CANCER. 2016;122(14):2268-2276

  Sexual function in male long-term survivors of childhood acute lymphoblastic leukemia

  Haavisto A; Henriksson M; Heikkinen R; Puukko-Viertomies L-R; Jahnukainen K
• Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2016;97(1):55-62

  Cardiac function in survivors of childhood acute myeloid leukemia treated with chemotherapy only: a NOPHO-AML study

  Jarfelt M; Andersen NH; Glosli H; Jahnukainen K; Onmundsson GKJ; Malmros J; Nysom K; Hasle H
• Letter: BONE MARROW TRANSPLANTATION. 2016;51(6):853-855

  Left ventricular mass and ambulatory blood pressure are increased in long-term survivors of childhood cancer after autologous SCT

  Vatanen A; Ojala TH; Sarkola T; Turanlahti M; Jahnukainen T; Saarinen-Pihkala UM; Jahnukainen K
• Article: LEUKEMIA & LYMPHOMA. 2016;57(3):700-707

  Minimal residual disease of leukemia and the quality of cryopreserved human ovarian tissue in vitro

  Asadi-Azarbaijani B; Sheikhi M; Nurmio M; Tinkanen H; Juvonen V; Dunkel L; Hovatta O; Oskam IC; Jahnukainen K
• Article: PEDIATRIC BLOOD & CANCER. 2016;63(1):83-92

  Acute Myeloid Leukemia in Adolescents and Young Adults Treated in Pediatric and Adult Departments in the Nordic Countries

  Wennstrom L; Edslev PW; Abrahamsson J; Norgaard JM; Floisand Y; Forestier E; Gustafsson G; Heldrup J; Hovi L; Jahnukainen K; Jonsson OG; Lausen B; Palle J; Zeller B; Holmberg E; Juliusson G; Stockelberg D; Hasle H
• Article: HUMAN REPRODUCTION. 2015;30(11):2463-2475

  A European perspective on testicular tissue cryopreservation for fertility preservation in prepubertal and adolescent boys

  Picton HM; Wyns C; Anderson RA; Goossens E; Jahnukainen K; Kliesch S; Mitchell RT; Pennings G; Rives N; Tournaye H; van Pelt AMM; Eichenlaub-Ritter U; Schlatt S
• Article: ACTA PAEDIATRICA. 2015;104(11):1182-1188

  Parents tend to underestimate cognitive deficits in 10- to 13-year-olds born with an extremely low birth weight.

  Koivisto A; Klenberg L; Tommiska V; Lano A; Laine M; Fellman V; Haavisto A; Finnish ELBW Cohort Study Group (FinELBW)
• Article: PEDIATRIC BLOOD & CANCER. 2015;62(11):2000-2006

  Radiotherapy-Related Arterial Intima Thickening and Plaque Formation in Childhood Cancer Survivors Detected With Very-High Resolution Ultrasound During Young Adulthood

  Vatanen A; Sarkola T; Ojala TH; Turanlahti M; Jahnukainen T; Saarinen-Pihkala UM; Jahnukainen K
• Article: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY. 2015;37(7):536-542

  High-dose Thiotepa as Consolidation Therapy With Autologous Hematopoietic Stem Cell Transplantation for High-risk Ewing Family Tumors: Single-institution Experience.

  Jahnukainen K; Kallio P; Koivusalo A; Saarinen-Pihkala UM
• Article: ANDROLOGY. 2015;3(5):947-955

  A detailed protocol for a rapid analysis of testicular cell populations using flow cytometry

  Rotgers E; Cisneros-Montalvo S; Jahnukainen K; Sandholm J; Toppari J; Nurmio M
• Article: PLOS ONE. 2015;10(7):e0133985

  Effect of Previous Chemotherapy on the Quality of Cryopreserved Human Ovarian Tissue In Vitro

  Azarbaijani BA; Sheikhi M; Oskam IC; Nurmio M; Laine T; Tinkanen H; Makinen S; Tanbo TG; Hovatta O; Jahnukainen K
• Article: BRITISH JOURNAL OF HAEMATOLOGY. 2015;169(6):859-867

  The applicability of the WHO classification in paediatric AML. A NOPHO-AML study.

  Sandahl JD; Kjeldsen E; Abrahamsson J; Ha S-Y; Heldrup J; Jahnukainen K; Jónsson ÓG; Lausen B; Palle J; Zeller B; Forestier E; Hasle H
• Review: CURRENT OPINION IN ENDOCRINOLOGY DIABETES AND OBESITY. 2015;22(3):217-223

  Testicular function and fertility preservation after treatment for haematological cancer

  Jahnukainen K; Mitchell RT; Stukenborg J-B
• Article: BONE MARROW TRANSPLANTATION. 2015;50(6):850-857

  Adverse health events and late mortality after pediatric allogeneic hematopoietic SCT-two decades of longitudinal follow-up

  Wilhelmsson M; Vatanen A; Borgstrom B; Gustafsson B; Taskinen M; Saarinen-Pihkala UM; Winiarski J; Jahnukainen K
• Article: ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES. 2015;32(3):522-527

  Repeatability and agreement of real time three-dimensional echocardiography measurements of left ventricular mass and synchrony in young patients.

  Ojala T; Mathur S; Vatanen A; Sinha MD; Jahnukainen K; Simpson J
• Article: HORMONE RESEARCH IN PAEDIATRICS. 2015;84(2):108-115

  Increased Body Adiposity and Serum Leptin Concentrations in Very Long-Term Adult Male Survivors of Childhood Acute Lymphoblastic Leukemia

  Jahnukainen K; Heikkinen R; Henriksson M; Andersson S; Ivaska KK; Puukko-Viertomies L-R; Makitie O
• Article: PEDIATRIC BLOOD & CANCER. 2014;61(12):2199-2202

  Assessment of renal function during high-dose methotrexate treatment in children with acute lymphoblastic leukemia.

  Ylinen E; Jahnukainen K; Saarinen-Pihkala UM; Jahnukainen T
• Article: TRANSPLANTATION. 2014;98(9):987-993

  Testicular function, semen quality, and fertility in young men after renal transplantation during childhood or adolescence.

  Tainio J; Jahnukainen K; Nurmio M; Pakarinen M; Jalanko H; Jahnukainen T
• Article: PEDIATRIC BLOOD & CANCER. 2014;61(9):1638-1643

  Renal, Gastrointestinal, and Hepatic Late Effects in Survivors of Childhood Acute Myeloid Leukemia Treated with Chemotherapy Only-A NOPHO-AML Study

  Skou A-S; Glosli H; Jahnukainen K; Jarfelt M; J'onmundsson GK; Malmros-Svennilson J; Nysom K; Hasle H
• Article: GENES CHROMOSOMES & CANCER. 2014;53(8):667-675

  Ploidy and clinical characteristics of childhood acute myeloid leukemia: A NOPHO-AML study.

  Sandahl JD; Kjeldsen E; Abrahamsson J; Ha S-Y; Heldrup J; Jahnukainen K; Jónsson OG; Lausen B; Palle J; Zeller B; Forestier E; Hasle H
• Article: MOLECULAR CANCER. 2014;13:155

  Bortezomib treatment causes long-term testicular dysfunction in young male mice

  Hou M; Eriksson E; Svechnikov K; Jahnukainen K; Soder O; Meinhardt A; Savendahl L
• Article: PEDIATRIC BLOOD & CANCER. 2014;61(6):1094-1100

  Adult Testicular Volume Predicts Spermatogenetic Recovery After Allogeneic HSCT in Childhood and Adolescence

  Wilhelmsson M; Vatanen A; Borgstrom B; Gustafsson B; Taskinen M; Saarinen-Pihkala UM; Winiarski J; Jahnukainen K
• Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2014;170(2):211-218

  Ovarian function after allogeneic hematopoietic stem cell transplantation in childhood and adolescence

  Vatanen A; Wilhelmsson M; Borgstrom B; Gustafsson B; Taskinen M; Saarinen-Pihkala UM; Winiarski J; Jahnukainen K
• Review: DUODECIM; LAAKETIETEELLINEN AIKAKAUSKIRJA. 2014;130(20):2050-2059

  [Solid tumors in children].

  Lohi O; Jahnukainen K; Huttunen P; Taskinen M; Taskinen S; Pakarinen M; Koivusalo A; Rintala R; Kanerva J; Grönroos M; Heikinheimo M; Vettenranta K
• Article: PEDIATRIC BLOOD & CANCER. 2013;60(12):1988-1995

  Pubertal Development and Fertility in Survivors of Childhood Acute Myeloid Leukemia Treated With Chemotherapy Only: A NOPHO-AML Study

  Molgaard-Hansen L; Skou A-S; Juul A; Glosli H; Jahnukainen K; Jarfelt M; Jonmundsson GK; Malmros J; Nysom K; Hasle H
• Article: BLOOD COAGULATION & FIBRINOLYSIS. 2013;24(7):749-756

  Antithrombin deficiency after prolonged asparaginase treatment in children with acute lymphoblastic leukemia

  Ranta S; Heyman MM; Jahnukainen K; Taskinen M; Saarinen-Pihkala UM; Frisk T; Soderhall S; Petrini P; Makipernaa AM-T
• Article: JOURNAL OF CANCER SURVIVORSHIP. 2013;7(3):404-412

  Potential gonadotoxicity of treatment in relation to quality of life and mental well-being of male survivors of childhood acute lymphoblastic leukemia

  Gunn ME; Lahteenmaki PM; Puukko-Viertomies L-R; Henriksson M; Heikkinen R; Jahnukainen K
• Article: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY. 2013;35(6):e254-e259

  Ultrahigh-risk group within the high-risk neuroblastoma category.

  Saarinen-Pihkala UM; Jahnukainen K; Wikström S; Koivusalo A; Karikoski R; Sariola H; Hovi L
• Article: PEDIATRIC TRANSPLANTATION. 2013;17(3):256-265

  Risk factors for impaired quality of life and psychosocial adjustment after pediatric heart, kidney, and liver transplantation.

  Haavisto A; Korkman M; Sintonen H; Holmberg C; Jalanko H; Lipsanen J; Qvist E
• Letter: LEUKEMIA. 2013;27(5):1183-1185

  Bone marrow remission status predicts leukemia contamination in ovarian biopsies collected for fertility preservation

  Jahnukainen K; Tinkanen H; Wikstrom A; Dunkel L; Saarinen-Pihkala UM; Makinen S; Azarbaijani BA; Oskam IC; Vettenranta K; Laine T; Kairisto V; Juvonen V
• Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2013;90(3):187-194

  Outcome of poor response paediatric AML using early SCT

  Wareham NE; Heilmann C; Abrahamsson J; Forestier E; Gustafsson B; Ha S-Y; Heldrup J; Jahnukainen K; Jonsson OG; Lausen B; Palle J; Zeller B; Hasle H
• Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2013;168(2):281-288

  Long-term skeletal consequences of childhood acute lymphoblastic leukemia in adult males: a cohort study

  Makitie O; Heikkinen R; Toiviainen-Salo S; Henriksson M; Puukko-Viertomies L-R; Jahnukainen K
• Article: PEDIATRIC TRANSPLANTATION. 2013;17(1):73-79

  Outcome of pediatric heart transplantation recipients treated with ventricular assist device.

  Jahnukainen T; Rautiainen P; Mattila IP; Puntila J; Haavisto A; Qvist E; Pihkala J; Peräsaari J; Merenmies J; Sairanen H; Jalanko H; Salminen JT
• Review: DUODECIM; LAAKETIETEELLINEN AIKAKAUSKIRJA. 2013;129(9):939-946

  [Childhood leukemia].

  Lohi O; Kanerva J; Taskinen M; Harila-Saari A; Rounioja S; Jahnukainen K; Lähteenmäki P; Vettenranta K
• Article: JOURNAL OF CLINICAL VIROLOGY. 2013;56(1):77-81

  BK polyomavirus-associated hemorrhagic cystitis among pediatric allogeneic bone marrow transplant recipients: treatment response and evidence for nosocomial transmission.

  Koskenvuo M; Dumoulin A; Lautenschlager I; Auvinen E; Mannonen L; Anttila V-J; Jahnukainen K; Saarinen-Pihkala UM; Hirsch HH
• Article: PEDIATRIC BLOOD & CANCER. 2012;59(7):1190-1197

  Thiotepa and melphalan based single, tandem, and triple high dose therapy and autologous stem cell transplantation for high risk neuroblastoma.

  Saarinen-Pihkala UM; Hovi L; Koivusalo A; Jahnukainen K; Karikoski R; Sariola H; Wikström S
• Review: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2012;97(12):4341-4351

  Present and Future Prospects of Male Fertility Preservation for Children and Adolescents

  Jahnukainen K; Stukenborg J-B
• Article: CANCER RESEARCH. 2012;72(20):5174-5178

  Autologous Ectopic Grafting of Cryopreserved Testicular Tissue Preserves the Fertility of Prepubescent Monkeys That Receive Sterilizing Cytotoxic Therapy

  Jahnukainen K; Ehmcke J; Nurmio M; Schlatt S
• Article: BLOOD. 2012;120(5):978-984

  Gemtuzumab ozogamicin as postconsolidation therapy does not prevent relapse in children with AML: results from NOPHO-AML 2004.

  Hasle H; Abrahamsson J; Forestier E; Ha S-Y; Heldrup J; Jahnukainen K; Jónsson ÓG; Lausen B; Palle J; Zeller B; Nordic Society of Paediatric Haematology and Oncol
• Article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2012;27(6):2594-2601

  Neuropsychological profile of children with kidney transplants.

  Haavisto A; Korkman M; Holmberg C; Jalanko H; Qvist E
• Article: SPERMATOGENESIS. 2012;2(2):79-87

  Peritubular myoid cells have a role in postnatal testicular growth.

  Nurmio M; Kallio J; Adam M; Mayerhofer A; Toppari J; Jahnukainen K
• Article: INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY. 2012;76(3):327-333

  Symptoms at presentation in children with sleep-related disorders.

  Liukkonen K; Virkkula P; Haavisto A; Suomalainen A; Aronen ET; Pitkäranta A; Kirjavainen T
• Letter: BLOOD. 2012;119(4):1087-1088

  High ERG gene expression is an unfavorable prognostic marker in pediatric acute myeloid leukemia Response

  Staffas A; Kanduri M; Hovland R; Rosenquist R; Ommen HB; Abrahamsson J; Forestier E; Jahnukainen K; Jonsson OG; Zeller B; Palle J; Lonnerholm G; Hasle H; Ehrencrona H; Palmqvist L
• Review: DUODECIM; LAAKETIETEELLINEN AIKAKAUSKIRJA. 2012;128(8):858-865

  [Effects of cancer treatments on gonads].

  Jahnukainen K
• Article: TRANSPLANTATION. 2011;92(12):1322-1326

  Quality of life in adult survivors of pediatric kidney transplantation.

  Haavisto A; Jalanko H; Sintonen H; Holmberg C; Qvist E
• Article: PEDIATRIC BLOOD & CANCER. 2011;57(7):1222-1229

  Quality of Health in Survivors of Childhood Acute Myeloid Leukemia Treated With Chemotherapy Only: A NOPHO-AML Study

  Molgaard-Hansen L; Glosli H; Jahnukainen K; Jarfelt M; Jonmundsson GK; Malmros-Svennilson J; Nysom K; Hasle H
• Article: BLOOD. 2011;118(22):5905-5913

  Presence of FLT3-ITD and high BAALC expression are independent prognostic markers in childhood acute myeloid leukemia

  Staffas A; Kanduri M; Hovland R; Rosenquist R; Ommen HB; Abrahamsson J; Forestier E; Jahnukainen K; Jonsson OG; Zeller B; Palle J; Lonnerholm G; Hasle H; Palmqvist L; Ehrencrona H
• Article: REPRODUCTION. 2011;142(5):711-721

  Hedgehog signalling promotes germ cell survival in the rat testis

  Makela J-A; Saario V; Bourguiba-Hachemi S; Nurmio M; Jahnukainen K; Parvinen M; Toppari J
• Article: FERTILITY AND STERILITY. 2011;96(4):837-842

  Semen quality and fertility in adult long-term survivors of childhood acute lymphoblastic leukemia

  Jahnukainen K; Heikkinen R; Henriksson M; Cooper TG; Puukko-Viertomies L-R; Makitie O
• Article: TRANSPLANTATION. 2011;92(4):404-409

  Pubertal development is normal in adolescents after renal transplantation in childhood.

  Tainio J; Qvist E; Vehmas R; Jahnukainen K; Hölttä T; Valta H; Jahnukainen T; Jalanko H
• Article: HUMAN REPRODUCTION. 2011;26(8):1945-1954

  Testicular recovery after irradiation differs in prepubertal and pubertal non-human primates, and can be enhanced by autologous germ cell transplantation

  Jahnukainen K; Ehmcke J; Quader MA; Huq MS; Epperly MW; Hergenrother S; Nurmio M; Schlatt S
• Article: TOXICOLOGY AND APPLIED PHARMACOLOGY. 2011;254(3):267-279

  Receptor tyrosine kinase inhibition causes simultaneous bone loss and excess bone formation within growing bone in rats

  Nurmio M; Joki H; Kallio J; Maatta JA; Vaananen HK; Toppari J; Jahnukainen K; Laitala-Leinonen T
• Meeting abstract: BONE. 2011;48:S255-S256

  Tyrosine kinase inhibition by imatinib mesylate interferes with bone growth and remodellation in rats

  Joki H; Nurmio M; Kallio J; Maatta J; Vaananen K; Toppari J; Jahnukainen K; Laitala-Leinonen T
• Article: BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM. 2011;25(2):287-302

  Testicular function and fertility preservation in male cancer patients

  Jahnukainen K; Ehmcke J; Hou M; Schlatt S
• Article: PEDIATRIC TRANSPLANTATION. 2011;15(2):184-192

  Visuospatial impairment in children and adolescents after liver transplantation.

  Haavisto A; Korkman M; Törmänen J; Holmberg C; Jalanko H; Qvist E
• Article: JOURNAL OF CLINICAL ONCOLOGY. 2011;29(3):310-315

  Response-guided induction therapy in pediatric acute myeloid leukemia with excellent remission rate.

  Abrahamsson J; Forestier E; Heldrup J; Jahnukainen K; Jónsson OG; Lausen B; Palle J; Zeller B; Hasle H
• Article: SEXUAL DEVELOPMENT. 2011;5(4):188-196

  Ontogenesis of Ap-2γ Expression in Rat Testes

  Hou M; Stukenborg J-B; Nurmio M; Andersson M; Toppari J; Soder O; Jahnukainen K
• Article: JOURNAL OF HEART AND LUNG TRANSPLANTATION. 2010;29(7):764-770

  Neurocognitive function of pediatric heart transplant recipients.

  Haavisto A; Korkman M; Jalanko H; Holmberg C; Qvist E
• Published conference paper: PEDIATRIC BLOOD & CANCER. 2009;53(2):274-280

  Testicular stem cells for fertility preservation: preclinical studies on male germ cell transplantation and testicular grafting.

  Schlatt S; Ehmcke J; Jahnukainen K
• Meeting abstract: BONE. 2009;44(2):S448

  Imatinib-treatment disturbs postnatal skeletal development in rats

  Nurmio M; Joki H; Kallio J; Maatta J; Toppari J; Jahnukainen K; Laitala-Leinonen T
• Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2009;94(6):2119-2122

  Effect of Childhood Acute Lymphoblastic Leukemia Therapy on Spermatogonia Populations and Future Fertility

  Nurmio M; Keros V; Lahteenmaki P; Salmi T; Kallajoki M; Jahnukainen K
• Article: JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS. 2009;30(2):107-114

  Mood is associated with snoring in preschool-aged children.

  Aronen ET; Liukkonen K; Simola P; Virkkula P; Uschakoff A; Korkman M; Kirjavainen T; Pitkäranta A
• Article: INTERNATIONAL JOURNAL OF ANDROLOGY. 2009;32(1):66-73

  Immunomagnetic separation of normal rat testicular cells from Roser's T-cell leukaemia cells is ineffective

  Hou M; Andersson M; Zheng C; Sundblad A; Soder O; Jahnukainen K
• Letter: EUROPEAN JOURNAL OF HAEMATOLOGY. 2009;82(1):75-76

  Severe congenital neutropenia and pegfilgrastim

  Lahteenmaki PM; Jahnukainen K; Pelliniemi T-T; Kainulainen L; Salmi TT
• Article: REPRODUCTIVE TOXICOLOGY. 2009;27(1):28-34

  Functional in vitro model to examine cancer therapy cytotoxicity in maturing rat testis

  Nurmio M; Toppari J; Kallio J; Hou M; Soder O; Jahnukainen K
• Article: REPRODUCTIVE TOXICOLOGY. 2008;25(4):442-446

  Adult reproductive functions after early postnatal inhibition by imatinib of the two receptor tyrosine kinases, c-kit and PDGFR, in the rat testis

  Nurmio M; Kallio J; Toppari J; Jahnukainen K
• Article: ENDOCRINOLOGY. 2008;149(6):2917-2922

  Estrogen receptor β selective ligand 5α-androstane-3β, 17β-diol stimulates spermatogonial deoxyribonucleic acid synthesis in rat seminiferous epithelium in vitro

  Wahlgren A; Svechnikov K; Strand M-L; Jahnukainen K; Parvinen M; Gustafsson J-A; Soder O
• Article: REPRODUCTION. 2007;134(6):767-779

  Decontamination of leukemic cells and enrichment of germ cells from testicular samples from rats with Roser's T-cell leukemia by flow cytometric sorting

  Hou M; Andersson M; Zheng C; Sundblad A; Soeder O; Jahnukainen K
• Meeting abstract: BLOOD. 2007;110(11):160B

  Gemtuzumab ozagamicin is well tolerated as post-consolidation therapy in childhood AML

  Hasle H; Abrahamsson J; Clausen N; Forestier E; Gustafsson G; Heldrup J; Hovi L; Jahnukainen K; Jonmundsson G; Palle J; Zeller B
• Article: ENDOCRINOLOGY. 2007;148(11):5459-5469

  Coxsackievirus and adenovirus receptor is up-regulated in migratory germ cells during passage of the blood-testis barrier

  Mirza M; Petersen C; Nordqvist K; Sollerbrant K
• Article: ENDOCRINOLOGY. 2007;148(11):5541-5548

  Irradiation causes acute and long-term spermatogonial depletion in cultured and xenotransplanted testicular tissue from juvenile nonhuman primates

  Jahnukainen K; Ehmcke J; Nurmio M; Schlatt S
• Editorial: INTERNATIONAL JOURNAL OF ANDROLOGY. 2007;30(4):418-419

  Fertility treatment in male cancer survivors -: Panel discussion

  Haugen TB; Schmidt KT; Kvist U; Skakkebaek NE; Jahnukainen K; Krausz C; Alfsen GC
• Published conference paper: INTERNATIONAL JOURNAL OF ANDROLOGY. 2007;30(4):366-376

  Inhibition of tyrosine kinases PDGFR and C-Kit by imatinib mesylate interferes with postnatal testicular development in the rat

  Nurmio M; Toppari J; Zaman F; Andersson A-M; Paranko J; Soeder O; Jahnukainen K
• Article: HUMAN REPRODUCTION. 2007;22(7):1899-1906

  Xenotransplantation of testicular tissue into nude mice can be used for detecting leukemic cell contamination

  Hou M; Andersson M; Eksborg S; Soder O; Jahnukainen K
• Article: HUMAN REPRODUCTION. 2007;22(5):1384-1395

  Methods of cryopreservation of testicular tissue with viable spermatogonia in pre-pubertal boys undergoing gonadotoxic cancer treatment

  Keros V; Hultenby K; Borgstrom B; Fridstrom M; Jahnukainen K; Hovattal O
• Article: HUMAN REPRODUCTION. 2007;22(4):1060-1067

  Effect of cold storage and cryopreservation of immature non-human primate testicular tissue on spermatogonial stem cell potential in xenografts

  Jahnukainen K; Ehmcke J; Hergenrother SD; Schlatt S
• Article: CANCER RESEARCH. 2006;66(7):3813-3818

  Testicular xenografts: A novel approach to study cytotoxic damage in juvenile primate testis

  Jahnukainen K; Ehmcke J; Schlatt S
• Review: PEDIATRIC RESEARCH. 2006;59(4):40R-47R

  Clinical potential and putative risks of fertility preservation in children utilizing gonadal tissue or germline stem cells

  Jahnukainen K; Ehmcke J; Söder O; Schlatt S
• Review: HORMONE RESEARCH IN PAEDIATRICS. 2006;66(4):153-161

  The Sertoli cell -: A hormonal target and "Super" nurse for germ cells that determines testicular size

  Petersen C; Soder O
• Article: CANCER RESEARCH. 2005;65(21):9999-10005

  Doxorubicin induces apoptosis in germ line stem cells in the immature rat testis and amifostine cannot protect against this cytotoxicity

  Hou M; Chrysis D; Nurmio M; Parvinen M; Eksborg S; Söder O; Jahnukainen K
• Article: CYTOKINE. 2005;32(1):51-59

  The p38 MAPK pathway mediates interleukin-1-induced Sertoli cell proliferation

  Petersen C; Svechnikov K; Fröysa B; Söder O
• Review: CURRENT DRUG TARGETS: IMMUNE, ENDOCRINE AND METABOLIC DISORDERS. 2004;4(1):67-74

  The paracrine role played by interleukin-1 alpha in the testis.

  Svechnikov K; Petersen C; Sultana T; Wahlgren A; Zetterström C; Colón E; Bornestaf C; Söder O
• Article: BIOLOGY OF REPRODUCTION. 2004;70(2):290-296

  Increased apoptosis occurring during the first wave of spermatogenesis is stage-specific and primarily affects midpachytene spermatocytes in the rat testis

  Jahnukainen K; Chrysis D; Hou M; Parvinen M; Eksborg S; Söder O
• Article: JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 2004;61(1):13-30

  Endotoxin and proinflammatory cytokines modulate Sertoli cell proliferation in vitro

  Petersen C; Fröysa B; Söder O
• Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2003;201(1-2):39-46

  EGF stimulates rat spermatogonial DNA synthesis in seminiferous tubule segments in vitro

  Wahab-Wahlgren A; Martinelle N; Holst M; Jahnukainen K; Parvinen M; Söder O
• Doctoral thesis: 2003

  Paracrine regulation of Sertoli cell proliferation

  Petersen C
• Review: ENDOCRINE DEVELOPMENT. 2003;5:124-135

  Testicular function after cancer treatment in childhood.

  Jahnukainen K; Söder O
• Article: ORTHODONTICS & CRANIOFACIAL RESEARCH. 2002;5(3):131-139

  Induced leukemia and antineoplastic agent carmustine cause permanent changes in craniofacial growth of immature rats.

  Karsila-Tenovuo S; Jahnukainen K; Peltomäki T; Salmi TT; Rönning O
• Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2002;186(1):37-47

  Interleukin-1 is a potent growth factor for immature rat Sertoli cells

  Petersen C; Boitani C; Fröysa B; Söder O
• Article: ORAL ONCOLOGY. 2001;37(7):586-592

  Disturbances in craniofacial morphology in children treated for solid tumors.

  Karsila-Tenovuo S; Jahnukainen K; Peltomäki T; Minn H; Kulmala J; Salmi TT; Rönning O
• Article: CANCER RESEARCH. 2001;61(17):6423-6427

  Amifostine protects against early but not late toxic effects of doxorubicin in infant rats

  Jahnukainen K; Jahnukainen T; Salmi TT; Svechnikov K; Eksborg S; Söder O
• Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2001;181(1-2):221-227

  Transforming growth factor-α stimulates proliferation of rat sertoli cells

  Petersen C; Boitani C; Fröysa B; Söder O
• Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2001;68(3):590-597

  Spectrum of perforin gene mutations in familial hemophagocytic lymphohistiocytosis.

  Göransdotter Ericson K; Fadeel B; Nilsson-Ardnor S; Söderhäll C; Samuelsson A; Janka G; Schneider M; Gürgey A; Yalman N; Révész T; Egeler R; Jahnukainen K; Storm-Mathiesen I; Haraldsson A; Poole J; de Saint Basile G; Nordenskjöld M; Henter J
• Article: CANCER RESEARCH. 2001;61(2):706-710

  Intratesticular transplantation of testicular cells from leukemic rats causes transmission of leukemia

  Jahnukainen K; Hou M; Petersen C; Setchell B; Söder O
• Article: EUROPEAN JOURNAL OF ORAL SCIENCES. 2000;108(5):426-431

  Catch-up growth and craniofacial dimensions following administration of the antineoplastic agent vincristine to young rats.

  Karsila S; Jahnukainen K; Salmi TT; Rönning O
• Article: BIOLOGY OF REPRODUCTION. 2000;63(2):482-487

  Stage-specific inhibition of deoxyribonucleic acid synthesis and induction of apoptosis by antracyclines in cultured rat spermatogenic cells

  Jahnukainen K; Hou M; Parvinen M; Eksborg S; Söder O
• Published conference paper: ANDROLOGIA. 2000;32(1):62-63

  Transforming growth factor-α stimulates Sertoli cell proliferation in vitro

  Petersen C; Fröysa B; Boitani C; Söder O
• Published conference paper: ANDROLOGIA. 2000;32(1):52-55

  The interleukin-1 system in the testis

  Söder O; Sultana T; Jonsson C; Wahlgren A; Petersen C; Holst M
• Article: DUODECIM; LAAKETIETEELLINEN AIKAKAUSKIRJA. 1999;115(2):131-135

  [Where did the blood cells vanish?].

  Eerola A; Pietilä S; Jahnukainen K; Routi T; Salmi TT
• Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 1998;146(1-2):121-127

  A rapid method of Sertoli cell isolation by DSA lectin, allowing mitotic analyses

  Scarpino S; Morena AR; Petersen C; Fröysa B; Söder O; Boitani C
• Article: ACTA PAEDIATRICA. 1998;87(6):638-643

  The clinical indications for identical pathogenesis of isolated and non-isolated testicular relapses in acute lymphoblastic leukaemia.

  Jahnukainen K; Salmi TT; Kristinsson J; Müller J; Madsen B; Gustafsson G
• Article: JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 1996;31(1-2):65-79

  Autoantigenicity of the basal compartment of seminiferous tubules in the rat.

  Saari T; Jahnukainen K; Pöllänen P
• Article: INTERNATIONAL JOURNAL OF ANDROLOGY. 1995;18(6):313-320

  Incidence of testicular mononuclear cell infiltrates in normal human males and in patients with germ cell neoplasia.

  Jahnukainen K; JørgensenN; Pöllänen P; Giwercman A; Skakkebaek NE
• Article: ANDROLOGIA. 1995;27(5):267-273

  Acute lymphoblastic leukaemia in rats induces pathomorphological changes in germ cells.

  Yagi A; Jahnukainen K; Paranko J
• Article: LEUKEMIA. 1995;9(5):908-914

  Reactions of Leydig cells and blood vessels to lymphoblastic leukemia in the rat testis.

  Jahnukainen K; Saari T; Salmi TT; Pöllänen P; Pelliniemi LJ
• Article: JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 1995;28(3):263-273

  EFFECTS OF TESTICULAR CYTOKINES ON PROLIFERATION OF RAT T-LEUKEMIC LYMPHOBLASTS IN-VITRO

  JAHNUKAINEN K; ATTERMO P; SAARI T; SALMI TT; VONEULER M; POLLANEN P; SODER O
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Gruppledare

• 

  João Pedro Alves-Lopes

  Biträdande Lektor

  E-postadress joao.pedro.lopes@ki.se

Alla medarbetare i gruppen

• Anu Haavisto

  Anknuten till Forskning

  E-postadress anu.haavisto@ki.se
• 

  Kirsi Jahnukainen

  Anknuten till Undervisning/Handledning | Docent

  E-postadress kirsi.jahnukainen@ki.se
• Antti Risto Mikael Koskela

  Postdoktor

  E-postadress mikael.koskela@ki.se
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  Tiago Macedo

  E-postadress tiago.macedo@ki.se
• Leah Nic Aodha

  Postdoktor

  E-postadress leah.nic.aodha@ki.se
• Cecilia Petersen

  Anknuten till Undervisning/Handledning

  E-postadress cecilia.petersen@ki.se
• Xiaoyan Wang

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  E-postadress xiaoyan.wang@ki.se

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