Unit of Molecular Toxicology

Publications

Selected publications

• Article: NANO TODAY. 2024;54:102084

  Immune profiling and tracking of two-dimensional transition metal dichalcogenides in cells and tissues

  Gazzi A; Fusco L; Orecchioni M; Keshavan S; Shin Y; Grivel J-C; Rinchai D; Ahmed EI; Elhanani O; Furesi G; Rauner M; Keren L; Ley K; Casiraghi C; Bedognetti D; Fadeel B; Delogu LG
• Article: MATTER. 2024;7(1):191-215

  Tuning the transformation and cellular signaling of 2D titanium carbide MXenes using a natural antioxidant

  Malina T; Hamawandi B; Toprak MS; Chen L; Bjork J; Zhou J; Rosen J; Fadeel B
• Article: ACS NANO. 2023;17(17):17451-17467

  Exploiting Mass Spectrometry to Unlock the Mechanism of Nanoparticle-Induced Inflammasome Activation.

  Gupta G; Kaur J; Bhattacharya K; Chambers BJ; Gazzi A; Furesi G; Rauner M; Fuoco C; Orecchioni M; Delogu LG; Haag L; Stehr JE; Thomen A; Bordes R; Malmberg P; Seisenbaeva GA; Kessler VG; Persson M; Fadeel B
• Article: NATURE NANOTECHNOLOGY. 2023;18(1):42-48

  Graphene oxide elicits microbiome-dependent type 2 immune responses via the aryl hydrocarbon receptor.

  Peng G; Sinkko HM; Alenius H; Lozano N; Kostarelos K; Bräutigam L; Fadeel B
• Article: NATURE COMMUNICATIONS. 2022;13(1):3798

  Biomarkers of nanomaterials hazard from multi-layer data.

  Fortino V; Kinaret PAS; Fratello M; Serra A; Saarimäki LA; Gallud A; Gupta G; Vales G; Correia M; Rasool O; Ytterberg J; Monopoli M; Skoog T; Ritchie P; Moya S; Vázquez-Campos S; Handy R; Grafström R; Tran L; Zubarev R; Lahesmaa R; Dawson K; Loeschner K; Larsen EH; Krombach F; Norppa H; Kere J; Savolainen K; Alenius H; Fadeel B; Greco D
• Article: SMALL. 2022;18(20):e2107816

  Two-Dimensional Transition Metal Dichalcogenides Trigger Trained Immunity in Human Macrophages through Epigenetic and Metabolic Pathways.

  Peng G; Keshavan S; Delogu L; Shin Y; Casiraghi C; Fadeel B
• Article: SMALL. 2020;16(21):e1907686

  Next-Generation Sequencing Reveals Differential Responses to Acute versus Long-Term Exposures to Graphene Oxide in Human Lung Cells.

  Mukherjee SP; Gupta G; Klöditz K; Wang J; Rodrigues AF; Kostarelos K; Fadeel B
• Article: CHEM. 2018;4(2):334-358

  Graphene Oxide Elicits Membrane Lipid Changes and Neutrophil Extracellular Trap Formation

  Mukherjee SP; Lazzaretto B; Hultenby K; Newman L; Rodrigues AF; Lozano N; Kostarelos K; Malmberg P; Fadeel B
• Article: SCIENCE SIGNALING. 2015;8(395):ra95

  Dichotomous roles for externalized cardiolipin in extracellular signaling: Promotion of phagocytosis and attenuation of innate immunity.

  Balasubramanian K; Maeda A; Lee JS; Mohammadyani D; Dar HH; Jiang JF; St Croix CM; Watkins S; Tyurin VA; Tyurina YY; Klöditz K; Polimova A; Kapralova VI; Xiong Z; Ray P; Klein-Seetharaman J; Mallampalli RK; Bayir H; Fadeel B; Kagan VE
• Article: NATURE NANOTECHNOLOGY. 2010;5(5):354-359

  Carbon nanotubes degraded by neutrophil myeloperoxidase induce less pulmonary inflammation.

  Kagan VE; Konduru NV; Feng W; Allen BL; Conroy J; Volkov Y; Vlasova II; Belikova NA; Yanamala N; Kapralov A; Tyurina YY; Shi J; Kisin ER; Murray AR; Franks J; Stolz D; Gou P; Klein-Seetharaman J; Fadeel B; Star A; Shvedova AA

Funding

Funders

• PERSEUS: Multi-Functional 2D Nanocrystal-Based Oncotherapy triggered by Computed Tomography

  European Commission
• Beyond Graphene: Exploring Biological Interactions of Transition Metal Dichalcogenides and MXenes

  Swedish Research Council
• MISTRA Environmental Nanosafety

  Swedish Foundation for Strategic Environmental Research
• Graphene Flagship

  European Commission
• Recognition and Degradation of Carbon Nanotubes and other Carbon-Based Nanomaterials: Implications for Human Health and the Environment

  Swedish Research Council for Environment Agricultural Sciences and Spatial Planning

Staff and contact

Head of Unit

• 

  Bengt Fadeel

  Professor | Docent

  Telephone +46852487737

  E-mail bengt.fadeel@ki.se

All members of the group

• 

  Bengt Fadeel

  Professor | Docent

  Telephone +46852487737

  E-mail bengt.fadeel@ki.se
• 

  Jasreen Kaur

  Postdoctoral Researcher

  E-mail jasreen.kaur@ki.se
• 

  Apiwit Sae-Fung

  Affiliated to Research

  E-mail apiwit.saefung@ki.se

Visiting address

Karolinska Institutet, Institute of Environmental Medicine, Nobels väg 13, Stockholm, 171 77, Sweden

Postal address

Karolinska Institutet, Institute of Environmental Medicine, Nobels väg 13, Stockholm, 171 77, Sweden