Unit of Molecular Toxicology

Publications

Selected publications

• Article: ACS NANO. 2025;19(20):19057-19079

  Nanodiamonds Interact with Primary Human Macrophages and Dendritic Cells Evoking a Vigorous Interferon Response

  Malina T; Kaur J; Martin S; Gallud A; Katayama S; Gazzi A; Orecchioni M; Petr M; Srejber M; Haag L; Hamawandi B; Toprak MS; Kere J; Delogu LG; Fadeel B
• Article: NANO TODAY. 2024;54:102084

  Immune profiling and tracking of two-dimensional transition metal dichalcogenides in cells and tissues

  Gazzi A; Fusco L; Orecchioni M; Keshavan S; Shin Y; Grivel J-C; Rinchai D; Ahmed EI; Elhanani O; Furesi G; Rauner M; Keren L; Ley K; Casiraghi C; Bedognetti D; Fadeel B; Delogu LG
• Article: MATTER. 2024;7(1):191-215

  Tuning the transformation and cellular signaling of 2D titanium carbide MXenes using a natural antioxidant

  Malina T; Hamawandi B; Toprak MS; Chen L; Bjork J; Zhou J; Rosen J; Fadeel B
• Article: ACS NANO. 2023;17(17):17451-17467

  Exploiting Mass Spectrometry to Unlock the Mechanism of Nanoparticle-Induced Inflammasome Activation

  Gupta G; Kaur J; Bhattacharya K; Chambers BJ; Gazzi A; Furesi G; Rauner M; Fuoco C; Orecchioni M; Delogu LG; Haag L; Stehr JE; Thomen A; Bordes R; Malmberg P; Seisenbaeva GA; Kessler VG; Persson M; Fadeel B
• Article: NATURE NANOTECHNOLOGY. 2023;18(1):42-48

  Graphene oxide elicits microbiome-dependent type 2 immune responses via the aryl hydrocarbon receptor

  Peng G; Sinkko HM; Alenius H; Lozano N; Kostarelos K; Brautigam L; Fadeel B
• Article: NATURE COMMUNICATIONS. 2022;13(1):3798

  Biomarkers of nanomaterials hazard from multi-layer data

  Fortino V; Kinaret PAS; Fratello M; Serra A; Saarimaki LA; Gallud A; Gupta G; Vales G; Correia M; Rasool O; Ytterberg J; Monopoli M; Skoog T; Ritchie P; Moya S; Vazquez-Campos S; Handy R; Grafstrom R; Tran L; Zubarev R; Lahesmaa R; Dawson K; Loeschner K; Larsen EH; Krombach F; Norppa H; Kere J; Savolainen K; Alenius H; Fadeel B; Greco D
• Article: NATURE NANOTECHNOLOGY. 2018;13(7):537-543

  Advanced tools for the safety assessment of nanomaterials

  Fadeel B; Farcal L; Hardy B; Vazquez-Campos S; Hristozov D; Marcomini A; Lynch I; Valsami-Jones E; Alenius H; Savolainen K
• Article: CHEM. 2018;4(2):334-358

  Graphene Oxide Elicits Membrane Lipid Changes and Neutrophil Extracellular Trap Formation

  Mukherjee SP; Lazzaretto B; Hultenby K; Newman L; Rodrigues AF; Lozano N; Kostarelos K; Malmberg P; Fadeel B
• Article: SCIENCE SIGNALING. 2015;8(395):ra95

  Dichotomous roles for externalized cardiolipin in extracellular signaling: Promotion of phagocytosis and attenuation of innate immunity

  Balasubramanian K; Maeda A; Lee JS; Mohammadyani D; Dar HH; Jiang JF; Croix CMS; Watkins S; Tyurin VA; Tyurina YY; Kloeditz K; Polimova A; Kapralova VI; Xiong Z; Ray P; Klein-Seetharaman J; Mallampalli RK; Bayir H; Fadeel B; Kagan VE
• Article: NATURE NANOTECHNOLOGY. 2010;5(5):354-359

  Carbon nanotubes degraded by neutrophil myeloperoxidase induce less pulmonary inflammation

  Kagan VE; Konduru NV; Feng W; Allen BL; Conroy J; Volkov Y; Vlasova II; Belikova NA; Yanamala N; Kapralov A; Tyurina YY; Shi J; Kisin ER; Murray AR; Franks J; Stolz D; Gou P; Klein-Seetharaman J; Fadeel B; Star A; Shvedova AA

Funding

Grants

• BACTERADIX: Advanced Nanomaterials to Target Genomic and Z-DNA for Bacterial Biofilm Eradication

  European Commission

  1 December 2024 - 30 November 2028
• PERSEUS: Multi-Functional 2D Nanocrystal-Based Oncotherapy triggered by Computed Tomography

  European Commission

  1 March 2023 - 28 February 2027
• Beyond Graphene: Exploring Biological Interactions of Transition Metal Dichalcogenides and MXenes

  Swedish Research Council

  1 January 2022 - 31 December 2025
• MISTRA Environmental Nanosafety

  Swedish Foundation for Strategic Environmental Research

  1 January 2014 - 30 September 2023
• Graphene Flagship

  European Commission

  1 October 2013 - 30 September 2023

Staff and contact

Head of Unit

• 

  Bengt Fadeel

  E-mail bengt.fadeel@ki.se

All members of the group

• 

  Vivek Gohel

  E-mail vivek.gohel@ki.se
• 

  Jasreen Kaur

  E-mail jasreen.kaur@ki.se
• 

  Pragati More

  E-mail pragati.more@ki.se
• 

  Zhiqi Yao

  E-mail zhiqi.yao@ki.se

Visiting address

Karolinska Institutet, Institute of Environmental Medicine, Nobels väg 13, Stockholm, 171 77, Sweden

Postal address

Karolinska Institutet, Institute of Environmental Medicine, Nobels väg 13, Stockholm, 171 77, Sweden

Other activities