Vivek Gohel | Karolinska Institutet

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Articles

Journal article: PHARMACOLOGICAL RESEARCH - REPORTS. 2025;4:100050
In human knee articular chondrocytic-spheroids, Orthogrit modulates TNF-α and IL-1β induced inflammation, oxidative stress, ECM catabolism, and improves locomotory behaviour in Caenorhabditis elegans
Balkrishna A; Gohel V; Pathak N; Tomer M; Dev R; Varshney A
Journal article: BIOMEDICINE & PHARMACOTHERAPY. 2025;187:118122
Polystyrene microplastic induced airway hyper-responsiveness, and pulmonary inflammation are mitigated by bronchom treatment in murine model of lung disease.
Balkrishna A; Tiwari A; Sinha S; Kumari A; Gohel V; Dev R; Bhattacharya K; Varshney A
Journal article: CNS NEUROSCIENCE & THERAPEUTICS. 2025;31(5):e70401
Neurogrit Gold Attenuates 6-OHDA-Induced Dopaminergic Neurodegeneration in Parkinson's Model of Caenorhabditis elegans by Reducing α-Synuclein Accumulation and Pink/Pdr-1 Driven Mitochondrial Dysfunction.
Balkrishna A; Pathak N; Singh R; Gohel V; Varshney Y; Dev R; Varshney A
Journal article: ANIMAL MODELS AND EXPERIMENTAL MEDICINE. 2025;8(4):728-738
Fevogrit, a polyherbal medicine, mitigates endotoxin (lipopolysaccharide)-induced fever in Wistar rats by regulating pro-inflammatory cytokine levels
Balkrishna A; Sharma S; Gohel V; Singh R; Tomer M; Dev R; Sinha S; Varshney A
Journal article: HELIYON. 2025;11(3):e41855
Livogrit mitigates ANIT-induced cholestasis-like symptoms in an in vivo model by curbing hepatic inflammation and regulating BAX, TGF-β, MMP-9 and α-SMA gene expression.
Balkrishna A; Paliwal R; Singh S; Singh R; Gohel V; Dev R; Bhattacharya K; Sinha S; Varshney A
Journal article: PHYTOCHEMICAL ANALYSIS. 2025;36(1):218-233
Comprehensive phytochemical profiling of Phyllanthus emblica L. flowers on UHPLC/MS quadrupole time of flight, HPTLC, HPLC, and NMR analytical platforms reveals functional metabolites with potent anti-inflammatory effects in human (THP-1) macrophages
Balkrishna A; Verma S; Rani MP; Joshi M; Tomer M; Gohel V; Nain P; Dev R; Varshney A
Journal article: BMC COMPLEMENTARY MEDICINE AND THERAPIES. 2024;24(1):386
Herbo-vitamin medicine Livogrit Vital ameliorates isoniazid induced liver injury (IILI) in human liver (HepG2) cells by decreasing isoniazid accumulation and oxidative stress driven hepatotoxicity
Balkrishna A; Gohel V; Tomer M; Dev R; Varshney A
Journal article: DRUG AND CHEMICAL TOXICOLOGY. 2024;47(6):987-1003
Livogrit prevents Amiodarone-induced toxicity in experimental model of human liver (HepG2) cells and Caenorhabditis elegans by regulating redox homeostasis
Balkrishna A; Gohel V; Pathak N; Bhattacharya K; Dev R; Varshney A
Journal article: DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY. 2024;50(11):938-951
Co-administration of Ayurvedic medicines Arshogrit and Jatyadi Ghrit, attenuate croton oil-induced hemorrhoids in rat model of recto-anal inflammation by modulating TNF-α and IL-1β levels
Balkrishna A; Tiwari A; Maity M; Tomer M; Varshney Y; Dev R; Sinha S; Varshney A
Journal article: SCIENTIFIC REPORTS. 2024;14(1):19443
Renogrit selectively protects against cisplatin-induced injury in human renal tubular cells and in Caenorhabditis elegans by harmonizing apoptosis and mitophagy
Balkrishna A; Gohel V; Pathak N; Joshi M; Singh R; Kumari A; Dev R; Varshney A
Journal article: PLOS ONE. 2023;18(11):e0293605
Renogrit attenuates Vancomycin-induced nephrotoxicity in human renal spheroids and in Sprague-Dawley rats by regulating kidney injury biomarkers and creatinine/urea clearance
Balkrishna A; Sharma S; Gohel V; Kumari A; Rawat M; Maity M; Sinha S; Dev R; Varshney A
Journal article: BIOMEDICINE & PHARMACOTHERAPY. 2023;163:114785
Divya-WeightGo combined with moderate aerobic exercise remediates adiposopathy, insulin resistance, serum biomarkers, and hepatic lipid accumulation in high-fat diet-induced obese mice
Balkrishna A; Sharma S; Maity M; Tomer M; Singh R; Gohel V; Dev R; Sinha S; Varshney A
Journal article: BIOMEDICINE & PHARMACOTHERAPY. 2023;160:114309
Anti-oxidant response of lipidom modulates lipid metabolism in Caenorhabditis elegans and in OxLDL-induced human macrophages by tuning inflammatory mediators
Balkrishna A; Gohel V; Pathak N; Singh R; Tomer M; Rawat M; Dev R; Varshney A
Journal article: PHARMACEUTICALS. 2022;16(1):63
Enteric-Coated Cologrit Tablet Exhibit Robust Anti-Inflammatory Response in Ulcerative Colitis-like In-Vitro Models by Attuning NFκB-Centric Signaling Axis
Balkrishna A; Singh R; Gohel V; Arora S; Dev R; Bhattacharya K; Varshney A
Journal article: FRONTIERS IN ENDOCRINOLOGY. 2022;13:1064532
Anti-hyperglycemic contours of Madhugrit are robustly translated in the Caenorhabditis elegans model of lipid accumulation by regulating oxidative stress and inflammatory response
Balkrishna A; Gohel V; Pathak N; Tomer M; Rawat M; Dev R; Varshney A
Journal article: FRONTIERS IN PHARMACOLOGY. 2022;13:1024830
Herbo-mineral formulation, Divya-Swasari-Vati averts SARS-CoV-2 pseudovirus entry into human alveolar epithelial cells by interfering with spike protein-ACE 2 interaction and IL-6/TNF-α/NF-κB signaling
Balkrishna A; Goswami S; Singh H; Gohel V; Dev R; Haldar S; Varshney A
Journal article: BIOENGINEERED. 2022;13(4):10811-10826
Livogrit Prevents Methionine-Cystine Deficiency Induced Nonalcoholic Steatohepatitis by Modulation of Steatosis and Oxidative Stress in Human Hepatocyte-Derived Spheroid and in Primary Rat Hepatocytes
Balkrishna A; Gohel V; Kumari P; Manik M; Bhattacharya K; Dev R; Varshney A
Journal article: PHYTOMEDICINE PLUS. 2021;1(3):100067
Livogrit ameliorates acetaldehyde-induced steatosis in HepG2 cells through modulation of lipogenesis and β-oxidation pathways
Balkrishna A; Gohel V; Singh R; Bhattacharya K; Varshney A
Journal article: MOLECULES. 2020;25(20):4849
Tri-Herbal Medicine Divya Sarva-Kalp-Kwath (Livogrit) Regulates Fatty Acid-Induced Steatosis in Human HepG2 Cells through Inhibition of Intracellular Triglycerides and Extracellular Glycerol Levels
Balkrishna A; Gohel V; Singh R; Joshi M; Varshney Y; Srivastava J; Bhattacharya K; Varshney A
Journal article: EXPERT OPINION ON DRUG DISCOVERY. 2020;15(7):823-832
Synthetic lethality on drug discovery: an update on cancer therapy
Yar MS; Haider K; Gohel V; Siddiqui NA; Kamal A
Journal article: CURRENT TOPICS IN MEDICINAL CHEMISTRY. 2019;19(17):1491-1511
Peptides as Potential Anticancer Agents
Aaghaz S; Gohel V; Kamal A
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All other publications

Preprint: BIORXIV. 2022
Anti-oxidant Response of Lipidom Modulates Lipid Metabolism in Caenorhabditis elegans and in OxLDL-Induced Human Macrophages by Tuning Inflammatory Mediators
Balkrishna A; Gohel V; Pathak N; Singh R; Tomer M; Rawat M; Dev R; Varshney A

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