Preventing age-related illness

It is becoming increasingly evident that our actions throughout life not only influence our lifespan but also significantly impact the aging process itself. Identifying which factors hold the greatest sway and are amenable to change constitutes an important aspect of our research.

Drawing from extensive data gathered from large population cohorts, our researchers have compiled comprehensive databases encompassing medical, social, psychological, functional, and biological dimensions. These invaluable resources enable us to delve deeper into the intricacies of the aging process, discerning both the risk factors predisposing individuals to age-related diseases and the protective factors that promote healthy aging. A seminal study conducted at Karolinska Institutet recently demonstrated the real potential for preventing memory disorders through a multifaceted approach integrating dietary guidance, physical activity, cognitive training, and the management of key risk factors such as blood pressure and lipid levels.

KI houses a robust research cluster specializing in the biological underpinnings of dementia-related illnesses. Here, scientists employ sophisticated techniques to monitor the progression of Alzheimer's disease, with the ultimate goal of developing efficacious treatments capable of halting or preventing its advancement. Additionally, our research endeavors extend to the development of tools aimed at enhancing quality of life amidst declining physical functions and escalating care needs.

Meeting the multifaceted challenges of aging demands interdisciplinary collaboration, incorporating psychosocial perspectives into medical research, and tackling the complexities of multimorbidity. Moreover, our efforts are dedicated to spearheading technological innovations aimed at mitigating age-related functional impairments.

The fruits of our ongoing research efforts hold immediate relevance for patients and public health initiatives alike. Through the concerted amalgamation of our collective expertise, we are poised to usher in an era where individuals can enjoy a better quality of life well into their later years. As we witness unprecedented strides in longevity and health, the prospect of aging free from dementia is no longer merely aspirational but increasingly within reach.


Rapidly changing demographics with steadily rising life-expectancy present a huge challenge to society in many respects. Age-related diseases and functional losses, such as physical disability, memory loss and dementia, affect not only patients but also their families. Today, some 25,000 people in Sweden develop dementia every year.

At the same time, people expect to maintain a high quality of life into very old age and that the functional losses that occur will have minimal consequences for individuals and society.