Sebastian Ols

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Publikationer
CV
Populärvetenskap och samverkan

Om mig

Civilingenjör i bioteknik, Kungliga Tekniska högskolan (KTH), Stockholm

Artiklar

Article: NPJ VACCINES. 2024;9(1):17
Three immunizations with Novavax's protein vaccines increase antibody breadth and provide durable protection from SARS-CoV-2
Lenart K; Cerveira RA; Hellgren F; Ols S; Sheward DJ; Kim C; Cagigi A; Gagne M; Davis B; Germosen D; Roy V; Alter G; Letscher H; Van Wassenhove J; Gros W; Gallouet A-S; Le Grand R; Kleanthous H; Guebre-Xabier M; Murrell B; Patel N; Glenn G; Smith G; Lore K
Article: IMMUNITY. 2023;56(10):2425-2441.e14
Multivalent antigen display on nanoparticle immunogens increases B cell clonotype diversity and neutralization breadth to pneumoviruses
Ols S; Lenart K; Cerveira RA; Miranda MC; Brunette N; Kochmann J; Corcoran M; Skotheim R; Philomin A; Cagigi A; Fiala B; Wrenn S; Marcandalli J; Hellgren F; Thompson EA; Lin A; Gegenfurtner F; Kumar A; Chen M; Phad GE; Graham BS; Perez L; Borst AJ; Hedestam GBK; Ruckwardt TJ; King NP; Lore K
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2023;80(7):189
Cell targeting and immunostimulatory properties of a novel Fcγ-receptor-independent agonistic anti-CD40 antibody in rhesus macaques
Yan X; Ols S; Arcoverde Cerveira R; Lenart K; Hellgren F; Ye K; Cagigi A; Buggert M; Nimmerjahn F; Hojen JF; Parera D; Pessara U; Fischer S; Lore K
Article: NATURE COMMUNICATIONS. 2023;14(1):3713
Unmodified rabies mRNA vaccine elicits high cross-neutralizing antibody titers and diverse B cell memory responses
Hellgren F; Cagigi A; Cerveira RA; Ols S; Kern T; Lin A; Eriksson B; Dodds MG; Jasny E; Schwendt K; Freuling C; Mueller T; Corcoran M; Hedestam GBK; Petsch B; Lore K
Article: NATURE COMMUNICATIONS. 2023;14(1):2164
Delayed generation of functional virus-specific circulating T follicular helper cells correlates with severe COVID-19
Yu M; Charles A; Cagigi A; Christ W; osterberg B; Falck-Jones S; Azizmohammadi L; ahlberg E; Falck-Jones R; Svensson J; Nie M; Warnqvist A; Hellgren F; Lenart K; Arcoverde Cerveira R; Ols S; Lindgren G; Lin A; Maecker H; Bell M; Johansson N; Albert J; Sundling C; Czarnewski P; Klingstroem J; Faernert A; Lore K; Smed-Soerensen A
Article: MOLECULAR THERAPY: METHODS & CLINICAL DEVELOPMENT. 2022;27:309-323
A third dose of the unmodified COVID-19 mRNA vaccine CVnCoV enhances quality and quantity of immune responses
Lenart K; Hellgren F; Ols S; Yan X; Cagigi A; Cerveira RA; Winge I; Hanczak J; Mueller SO; Jasny E; Schwendt K; Rauch S; Petsch B; Lore K
Article: JCI INSIGHT. 2021;6(22):e151463
Airway antibodies emerge according to COVID-19 severity and wane rapidly but reappear after SARS-CoV-2 vaccination
Cagigi A; Yu M; Osterberg B; Svensson J; Falck-Jones S; Vangeti S; Ahlberg E; Azizmohammadi L; Warnqvist A; Falck-Jones R; Gubisch PC; Odemis M; Ghafoor F; Eisele M; Lenart K; Bell M; Johansson N; Albert J; Salde J; Pettie DD; Murphy MP; Carter L; King NP; Ols S; Normark J; Ahlm C; Forsell MN; Farnert A; Lore K; Smed-Sorensen A
Article: IMMUNITY. 2021;54(9):2005-2023.e10
Limited access to antigen drives generation of early B cell memory while restraining the plasmablast response
Glaros V; Rauschmeier R; Artemov AV; Reinhardt A; Ols S; Emmanouilidi A; Gustafsson C; You Y; Mirabello C; Bjorklund AK; Perez L; King NP; Mansson R; Angeletti D; Lore K; Adameyko I; Busslinger M; Kreslavsky T
Article: JOURNAL OF IMMUNOLOGY. 2021;207(4):1033-1043
Activation and Kinetics of Circulating T Follicular Helper Cells, Specific Plasmablast Response, and Development of Neutralizing Antibodies following Yellow Fever Virus Vaccination
Sandberg JT; Ols S; Lofling M; Varnait R; Lindgren G; Nilsson O; Rombo L; Kale M; Lore K; Blom K; Ljunggren H-G; Lindgren G; Nilsson O; Rombo L; Kale M
Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2020;481:112792
Stabilization of blood for long-term storage can affect antibody-based recognition of cell surface markers
Silva MH; Lepzien R; Ols S; Dahlberg B; Grunewald J; Lore K; Smed-Sorensen A; Correia-Neves M; Empadinhas N; Farnert A; Kallenius G; Sundling C
Article: JOURNAL OF CLINICAL INVESTIGATION. 2020;130(5):2332-2346
Live attenuated pertussis vaccine BPZE1 induces a broad antibody response in humans
Lin A; Apostolovic D; Jahnmatz M; Liang F; Ols S; Tecleab T; Wu C; van Hage M; Solovay K; Rubin K; Locht C; Thorstensson R; Thalen M; Lore K
Article: CELL REPORTS. 2020;30(12):3964-3971.e7
Route of Vaccine Administration Alters Antigen Trafficking but Not Innate or Adaptive Immunity
Ols S; Yang L; Thompson EA; Pushparaj P; Tran K; Liang F; Lin A; Eriksson B; Hedestam GBK; Wyatt RT; Lore K
Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2019;472:16-24
Comparative analysis of the germinal center response by flow cytometry and immunohistology
Lindgren G; Ols S; Thompson EA; Lore K
Article: CELL. 2019;176(6):1420-1431.e17
Induction of Potent Neutralizing Antibody Responses by a Designed Protein Nanoparticle Vaccine for Respiratory Syncytial Virus
Marcandalli J; Fiala B; Ols S; Perotti M; de van der Schueren W; Snijder J; Hodge E; Benhaim M; Ravichandran R; Carter L; Sheffler W; Brunner L; Lawrenz M; Dubois P; Lanzavecchia A; Sallusto F; Lee KK; Veesler D; Correnti CE; Stewart LJ; Baker D; Lore K; Perez L; King NP
Article: JCI INSIGHT. 2018;3(10):120692
TLR-adjuvanted nanoparticle vaccines differentially influence the quality and longevity of responses to malaria antigen Pfs25
Thompson EA; Ols S; Miura K; Rausch K; Narum DL; Spangberg M; Juraska M; Wille-Reece U; Weiner A; Howard RF; Long CA; Duffy PE; Johnston L; O'neil CP; Lore K
Article: JOURNAL OF IMMUNOLOGY. 2018;200(1):286-294
Rhesus Macaque Myeloid-Derived Suppressor Cells Demonstrate T Cell Inhibitory Functions and Are Transiently Increased after Vaccination
Lin A; Liang F; Thompson EA; Vono M; Ols S; Lindgren G; Hassett K; Salter H; Ciaramella G; Lore K
Article: MOLECULAR THERAPY. 2017;25(12):2635-2647
Efficient Targeting and Activation of Antigen Presenting Cells In Vivo after Modified mRNA Vaccine Administration in Rhesus Macaques
Liang F; Lindgren G; Lin A; Thompson EA; Ols S; Rohss J; John S; Hassett K; Yuzhakov O; Bahl K; Brito LA; Salter H; Ciaramella G; Lore K
Article: FRONTIERS IN IMMUNOLOGY. 2017;8:1539
Induction of Robust B Cell Responses after Influenza mRNA Vaccination Is Accompanied by Circulating Hemagglutinin-Specific ICOS+ PD-1+CXCR3+T Follicular Helper Cells
Lindgren G; Ols S; Liang F; Thompson EA; Lin A; Hellgren F; Bahl K; John S; Yuzhakov O; Hassett KJ; Brito LA; Salter H; Ciaramella G; Lore K

Alla övriga publikationer

Corrigendum: NATURE COMMUNICATIONS. 2023;14(1):4080
Unmodified rabies mRNA vaccine elicits high cross-neutralizing antibody titers and diverse B cell memory responses (vol 14, 3713, 2023)
Hellgren F; Cagigi A; Cerveira RA; Ols S; Kern T; Lin A; Eriksson B; Dodds MG; Jasny E; Schwendt K; Freuling C; Mueller T; Corcoran M; Hedestam GKB; Petsch B; Lore K; Usa C
Thesis / dissertation: 2022
Cellular and molecular mechanisms for induction of broad anti-viral B cell responses through vaccination
Ols, Sebastian
Review: JOURNAL OF INTERNAL MEDICINE. 2022;291(1):32-50
Immunity to SARS-CoV-2 induced by infection or vaccination
Castro Dopico X; Ols S; Lore K; Karlsson Hedestam GB
Editorial comment: NATURE BIOMEDICAL ENGINEERING. 2019;3(5):331-332
Imaging the early fate of mRNA vaccines
Ols S; Lore K
Corrigendum: FRONTIERS IN IMMUNOLOGY. 2019;10:614
Induction of Robust B Cell Responses After Influenza mRNA Vaccination Is Accompanied by Circulating Hemagglutinin-Specific ICOS+ PD-1+ CXCR3+ T Follicular Helper Cells (vol 8, 1539, 2017)
Lindgren G; Ols S; Liang F; Thompson EA; Lin A; Hellgren F; Bahl K; John S; Yuzhakov O; Hassett KJ; Brito LA; Salter H; Ciaramella G; Lore K

Anställningar

Postdoktor, Medicin, Solna, Karolinska Institutet, 2023-2025

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Medicine Doktorsexamen, Institutionen för medicin, Solna, Karolinska Institutet, 2022

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