Sebastian Ols
Postdoctoral Researcher
E-mail: sebastian.ols@ki.se
Visiting address: BioClinicum J7:20, 17176 Stockholm
Postal address: K2 Medicin, Solna, K2 Infekt Broliden K, 171 77 Stockholm
About me
- Sebastian is currently a Postdoctoral Fellow in the King Lab at the Institute
for Protein Design, University of Washington, Seattle and affiliated to
Karolinska Institutet.
I completed my doctoral studies in the research group of Professor Karin
Loré studying how B cell responses are modulated by nanoparticle vaccine
formulations. In particular, I studied how the breadth and potency of
anti-viral antibody and B cell responses is affected by antigen display. My
thesis was titled: "Cellular and molecular mechanisms for induction of broad
anti-viral B cell responses through vaccination [1]."
2023 Sven Gard Prize for Best Thesis in Virology at Karolinska Institutet in
2022 [2]
2017-2022 PhD in Medical Science, Karolinska Institutet, Stockholm, Sweden.
2014-2016 Master of Science in Medical Biotechnology, KTH Royal Institute of
Technology, Stockholm, Sweden.
2010-2014 Bachelor of Science in Biotechnology, KTH Royal Institute of
Technology, Stockholm, Sweden.
[1] https://openarchive.ki.se/xmlui/handle/10616/48115?_ga=2.55701864.275550828.1678085801-95590212.1661844809&pk_vid=9c47331a68b2c4c71678442012ba3098
[2] https://news.ki.se/katie-healy-and-sebastian-ols-are-the-recipients-of-sven-gards-scholarship-2023
Research
- A better understanding of how the immune system interacts with vaccines will
allow us to rationally select formulations that have the capacity to elicit
stronger immunity and can be advanced into clinical testing. Our studies can
ultimately provide information on vaccine antigen persistence, distribution,
and the immunological steps for the onset of B cell responses to understand
the generation of high-quality and durable antibody responses.
Articles
- Article: NATURE. 2025;638(8050):553-561Dowling QM; Park Y-J; Fries CN; Gerstenmaier NC; Ols S; Yang EC; Wargacki AJ; Dosey A; Hsia Y; Ravichandran R; Walkey CD; Burrell AL; Veesler D; Baker D; King NP
- Article: JCI INSIGHT. 2024;9(9):e175401Hellgren F; Rosdahl A; Cerveira RA; Lenart K; Ols S; Gwon Y-D; Kurt S; Delis AM; Joas G; Evander M; Normark J; Ahlm C; Forsell MNE; Cajander S; Lore K
- Article: NPJ VACCINES. 2024;9(1):17Lenart K; Cerveira RA; Hellgren F; Ols S; Sheward DJ; Kim C; Cagigi A; Gagne M; Davis B; Germosen D; Roy V; Alter G; Letscher H; Van Wassenhove J; Gros W; Gallouet A-S; Le Grand R; Kleanthous H; Guebre-Xabier M; Murrell B; Patel N; Glenn G; Smith G; Lore K
- Article: IMMUNITY. 2023;56(10):2425-2441.e14Ols S; Lenart K; Cerveira RA; Miranda MC; Brunette N; Kochmann J; Corcoran M; Skotheim R; Philomin A; Cagigi A; Fiala B; Wrenn S; Marcandalli J; Hellgren F; Thompson EA; Lin A; Gegenfurtner F; Kumar A; Chen M; Phad GE; Graham BS; Perez L; Borst AJ; Hedestam GBK; Ruckwardt TJ; King NP; Lore K
- Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2023;80(7):189Yan X; Ols S; Arcoverde Cerveira R; Lenart K; Hellgren F; Ye K; Cagigi A; Buggert M; Nimmerjahn F; Hojen JF; Parera D; Pessara U; Fischer S; Lore K
- Article: NATURE COMMUNICATIONS. 2023;14(1):3713Hellgren F; Cagigi A; Cerveira RA; Ols S; Kern T; Lin A; Eriksson B; Dodds MG; Jasny E; Schwendt K; Freuling C; Mueller T; Corcoran M; Hedestam GBK; Petsch B; Lore K
- Article: NATURE COMMUNICATIONS. 2023;14(1):2164Yu M; Charles A; Cagigi A; Christ W; osterberg B; Falck-Jones S; Azizmohammadi L; ahlberg E; Falck-Jones R; Svensson J; Nie M; Warnqvist A; Hellgren F; Lenart K; Arcoverde Cerveira R; Ols S; Lindgren G; Lin A; Maecker H; Bell M; Johansson N; Albert J; Sundling C; Czarnewski P; Klingstroem J; Faernert A; Lore K; Smed-Soerensen A
- Article: MOLECULAR THERAPY METHODS & CLINICAL DEVELOPMENT. 2022;27:309-323Lenart K; Hellgren F; Ols S; Yan X; Cagigi A; Cerveira RA; Winge I; Hanczak J; Mueller SO; Jasny E; Schwendt K; Rauch S; Petsch B; Lore K
- Article: JCI INSIGHT. 2021;6(22):e151463Cagigi A; Yu M; Osterberg B; Svensson J; Falck-Jones S; Vangeti S; Ahlberg E; Azizmohammadi L; Warnqvist A; Falck-Jones R; Gubisch PC; Odemis M; Ghafoor F; Eisele M; Lenart K; Bell M; Johansson N; Albert J; Salde J; Pettie DD; Murphy MP; Carter L; King NP; Ols S; Normark J; Ahlm C; Forsell MN; Farnert A; Lore K; Smed-Sorensen A
- Article: IMMUNITY. 2021;54(9):2005-2023.e10Glaros V; Rauschmeier R; Artemov AV; Reinhardt A; Ols S; Emmanouilidi A; Gustafsson C; You Y; Mirabello C; Bjorklund AK; Perez L; King NP; Mansson R; Angeletti D; Lore K; Adameyko I; Busslinger M; Kreslavsky T
- Article: JOURNAL OF IMMUNOLOGY. 2021;207(4):1033-1043Sandberg JT; Ols S; Lofling M; Varnait R; Lindgren G; Nilsson O; Rombo L; Kale M; Lore K; Blom K; Ljunggren H-G; Lindgren G; Nilsson O; Rombo L; Kale M
- Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2020;481:112792Silva MH; Lepzien R; Ols S; Dahlberg B; Grunewald J; Lore K; Smed-Sorensen A; Correia-Neves M; Empadinhas N; Farnert A; Kallenius G; Sundling C
- Article: JOURNAL OF CLINICAL INVESTIGATION. 2020;130(5):2332-2346Lin A; Apostolovic D; Jahnmatz M; Liang F; Ols S; Tecleab T; Wu C; van Hage M; Solovay K; Rubin K; Locht C; Thorstensson R; Thalen M; Lore K
- Article: CELL REPORTS. 2020;30(12):3964-3971.e7Ols S; Yang L; Thompson EA; Pushparaj P; Tran K; Liang F; Lin A; Eriksson B; Hedestam GBK; Wyatt RT; Lore K
- Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2019;472:16-24Lindgren G; Ols S; Thompson EA; Lore K
- Article: CELL. 2019;176(6):1420-1431.e17Marcandalli J; Fiala B; Ols S; Perotti M; de van der Schueren W; Snijder J; Hodge E; Benhaim M; Ravichandran R; Carter L; Sheffler W; Brunner L; Lawrenz M; Dubois P; Lanzavecchia A; Sallusto F; Lee KK; Veesler D; Correnti CE; Stewart LJ; Baker D; Lore K; Perez L; King NP
- Article: JCI INSIGHT. 2018;3(10):120692Thompson EA; Ols S; Miura K; Rausch K; Narum DL; Spangberg M; Juraska M; Wille-Reece U; Weiner A; Howard RF; Long CA; Duffy PE; Johnston L; O'neil CP; Lore K
- Article: JOURNAL OF IMMUNOLOGY. 2018;200(1):286-294Lin A; Liang F; Thompson EA; Vono M; Ols S; Lindgren G; Hassett K; Salter H; Ciaramella G; Lore K
- Article: MOLECULAR THERAPY. 2017;25(12):2635-2647Liang F; Lindgren G; Lin A; Thompson EA; Ols S; Rohss J; John S; Hassett K; Yuzhakov O; Bahl K; Brito LA; Salter H; Ciaramella G; Lore K
- Article: FRONTIERS IN IMMUNOLOGY. 2017;8:1539Lindgren G; Ols S; Liang F; Thompson EA; Lin A; Hellgren F; Bahl K; John S; Yuzhakov O; Hassett KJ; Brito LA; Salter H; Ciaramella G; Lore K
All other publications
- Corrigendum: NATURE COMMUNICATIONS. 2023;14(1):4080Hellgren F; Cagigi A; Cerveira RA; Ols S; Kern T; Lin A; Eriksson B; Dodds MG; Jasny E; Schwendt K; Freuling C; Mueller T; Corcoran M; Hedestam GKB; Petsch B; Lore K; Usa C
- Doctoral thesis: 2022Ols S
- Review: JOURNAL OF INTERNAL MEDICINE. 2022;291(1):32-50Castro Dopico X; Ols S; Lore K; Karlsson Hedestam GB
- Editorial comment: NATURE BIOMEDICAL ENGINEERING. 2019;3(5):331-332Ols S; Lore K
- Corrigendum: FRONTIERS IN IMMUNOLOGY. 2019;10:614Lindgren G; Ols S; Liang F; Thompson EA; Lin A; Hellgren F; Bahl K; John S; Yuzhakov O; Hassett KJ; Brito LA; Salter H; Ciaramella G; Lore K
Employments
- Postdoctoral Researcher, Department of Medicine, Karolinska Institutet, 2023-2025
Degrees and Education
- Degree Of Doctor Of Philosophy, Department of Medicine, Solna, Karolinska Institutet, 2022