Rongrong Fan

Rongrong Fan

Senior Forskare | Docent
E-postadress: rongrong.fan@ki.se
Besöksadress: Blickagången 16, 14152 Flemingsberg
Postadress: H7 Medicin, Huddinge, H7 BioNut Fan, 171 77 Stockholm

Om mig

  • Lab page:
    https://ki.se/en/bionut/liver-and-monocyte-remodelling-in-non-alcoholic-fatty-liver-disease-and-cardiovascular

    Research grants:
    The Rolf Luft Grant for Instrumentation 2022
    SRP diabetes 2022
    KI faculty-funded senior researcher 2021
    EFSD / Novo Nordisk Future Leaders Award 2021
    Cancerfonden
    Swedish research council (Vetenskapsrådet)
    CIMED
    NOVO NORDISK Foundation
    KI Doctoral funding
    Åke Wibergs Stiftelse
    Diabetes Wellness Sverige Foundation
    EFSD / Lilly research fellowship
    KI foundation

    Commission of trust:
    Editorial board: Frontiers in Endocrinology 2021-.
    Guest editor: Frontiers in Endocrinology 2020-2021.
    Steering Committee: lipoprotein research networks in KI south campus
    (supported by CIMED).
    Grant evaluation task for: French National Research Agency (ANR)
    Grant review panel: Cancerfonden, KID
    Invited reviewer in: Nat Com, JCI, eLife, JBC, FASEB J, Diabetologia, etc.
    Poster assesment committee: Epigenomics, nuclear receptor and diseases summer school. Spetses, 2019.
    Poster assesment committee: 7th Endometrial SRP Diabetes Joint Retreat. Stockholm, 2017.
    Poster assesment committee: Epigenomics, nuclear receptor and diseases summer school. Spetses, 2017.

Forskningsbeskrivning

  • My research combines the phenotypic/clinical analysis with multi-OMICs approaches to understand the fundamental question of how over-nutritional
    signals alter chromatin remodelling to promote metabolic disease development. We have so far analyzed different patient samples in the transcriptomic, cistromic and epigenomic levels and identified a group of interesting candidates involved in species-conserved and disease-relevant regulation of glucose and lipid metabolism. Of particular interest is the transcription factor coregulator GPS2, the dysregulation of which is associated with de-repressed inflammation and impaired lipid oxidation pathways, leading to type 2 diabetes and liver disease progression.
    The ongoing research activity involves further investigation of the coregulator-based mechanisms in the genomic and epigenomic level in various
    disease contexts. Understanding such pathways is crucial for better deciphering disease mechanisms which is ultimately required for identifying
    novel targets with diagnostic and intervention potential.

Undervisning

  • Main supervisor of 2 ongoing PhD student
    Cosupervisor of 1 ongoing PhD student and 2 completed PhD students
    Project supervisor of 5 bachelor students and 2 Master student
    Evaluation of 4 Master theses
    Half-time committee of 5 PhD students
    Mentor of 2 PhD students
    More than 200 teaching hours in Bachelor, Master and PhD courses
    Professional university pedagogy training (equivalent to more than 5 weeks)

Artiklar

Alla övriga publikationer

Forskningsbidrag

Anställningar

  • Senior Forskare, Medicin, Huddinge, Karolinska Institutet, 2024-
  • Senior Forskare, Biovetenskaper och näringslära, Karolinska Institutet, 2024-2024
  • Senior Forskare, Biovetenskaper och näringslära, Karolinska Institutet, 2022-2024

Examina och utbildning

  • Docent, Cell- och molekylärbiologi, Karolinska Institutet, 2022

Nyheter från KI

Kalenderhändelser från KI