Rongrong Fan

Lab page:
https://ki.se/en/bionut/liver-and-monocyte-remodelling-in-non-alcoholic-fatty-liver-disease-and-cardiovascular

Research grants:

Swedish research council (Vetenskapsrådet)

EFSD / Novo Nordisk Future Leaders Award 

The Rolf Luft Grant for Instrumentation 

My research combines the phenotypic/clinical analysis with multi-OMICs approaches to understand the fundamental question of how over-nutritional
signals alter chromatin remodelling to promote metabolic disease development. We have so far analyzed different patient samples in the transcriptomic, cistromic and epigenomic levels and identified a group of interesting candidates involved in species-conserved and disease-relevant regulation of glucose and lipid metabolism. Of particular interest is the transcription factor coregulator GPS2, the dysregulation of which is associated with de-repressed inflammation and impaired lipid oxidation pathways, leading to type 2 diabetes and liver disease progression.
The ongoing research activity involves further investigation of the coregulator-based mechanisms in the genomic and epigenomic level in various
disease contexts. Understanding such pathways is crucial for better deciphering disease mechanisms which is ultimately required for identifying
novel targets with diagnostic and intervention potential.

Main supervisor of 3 ongoing PhD student and 1 postdoc
Cosupervisor of 1 ongoing PhD student and 2 completed PhD students
Project supervisor of 5 bachelor students and 2 Master student
More than 200 teaching hours in Bachelor, Master and PhD courses

Master level course director
Professional university pedagogy training (equivalent to more than 5 weeks)