Rongrong Fan

Rongrong Fan

Principal Researcher | Docent
Visiting address: Blickagången 16, 14152 Flemingsberg
Postal address: H7 Medicin, Huddinge, H7 BioNut Fan, 171 77 Stockholm

About me

  • Lab page:
    https://ki.se/en/bionut/liver-and-monocyte-remodelling-in-non-alcoholic-fatty-liver-disease-and-cardiovascular

    Research grants:

    Swedish research council (Vetenskapsrådet)

    EFSD / Novo Nordisk Future Leaders Award 


  • Cancerfonden

    The Rolf Luft Grant for Instrumentation 


  • SRP diabetes 

  • KI faculty-funded senior researcher 

  • CIMED
    NOVO NORDISK Foundation
    KI Doctoral funding
    Åke Wibergs Stiftelse
    Diabetes Wellness Sverige Foundation
    EFSD / Lilly research fellowship
    KI foundation

    Commission of trust:
    Editorial board: Frontiers in Endocrinology 2021-.
    Guest editor: Frontiers in Endocrinology 2020-2021.
    Steering Committee: lipoprotein research networks in KI south campus
    (supported by CIMED).
    Grant evaluation task for: ANR, VR, FWF, KID, etc
    Invited reviewer in: Nat Com, JCI, eLife, JBC, FASEB J, Diabetologia, etc.
    Organizing committee and chairs for domestic and international conferences.

Research

  • My research combines the phenotypic/clinical analysis with multi-OMICs approaches to understand the fundamental question of how over-nutritional
    signals alter chromatin remodelling to promote metabolic disease development. We have so far analyzed different patient samples in the transcriptomic, cistromic and epigenomic levels and identified a group of interesting candidates involved in species-conserved and disease-relevant regulation of glucose and lipid metabolism. Of particular interest is the transcription factor coregulator GPS2, the dysregulation of which is associated with de-repressed inflammation and impaired lipid oxidation pathways, leading to type 2 diabetes and liver disease progression.
    The ongoing research activity involves further investigation of the coregulator-based mechanisms in the genomic and epigenomic level in various
    disease contexts. Understanding such pathways is crucial for better deciphering disease mechanisms which is ultimately required for identifying
    novel targets with diagnostic and intervention potential.

Teaching

  • Main supervisor of 3 ongoing PhD student and 1 postdoc
    Cosupervisor of 1 ongoing PhD student and 2 completed PhD students
    Project supervisor of 5 bachelor students and 2 Master student
    More than 200 teaching hours in Bachelor, Master and PhD courses

    Master level course director
    Professional university pedagogy training (equivalent to more than 5 weeks)

Articles

All other publications

Grants

Employments

  • Principal Researcher, Department of Medicine, Huddinge, Karolinska Institutet, 2024-
  • Principal Researcher, Department of Biosciences and Nutrition, Karolinska Institutet, 2024-2024

Degrees and Education

  • Docent, Karolinska Institutet, 2022

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