Karin Wirdefeldt

Om mig
Publikationer
CV
Populärvetenskap och samverkan

Om mig

Jag är docent och adjungerad professor i neuroepidemiologi vid
Institutionen för medicinsk epidemiologi och biostatistik [1] och
överläkare vid Medicinsk Enhet Neurologi, Karolinska
Universitetssjukhuset Solna.
[1] https://ki.se/meb

Forskningsbeskrivning

*Handledning av doktorander*
* Xiaoying Kang [1]
[1] https://medarbetare.ki.se/people/xiaoying-kang

Artiklar

Article: NEUROEPIDEMIOLOGY. 2024;58(4):256-263
Associations between Sleep Disorders and Impulsive-Compulsive Behaviors in Parkinson's Disease: A Prospective Cohort Study
Ye M; Kang X; Karlsson IK; Wang Y; Ji Q; Liu Q; Xu X; Hagg S; Fang F; Wirdefeldt K; Zhan Y
Article: PARKINSON'S DISEASE. 2023;2023:1-7
Sex Differences in the Allele Distribution of PGLYRP2 Variant rs892145 in Parkinson's Disease
Ran C; Wirdefeldt K; Sydow O; Svenningsson P; Diaz Heijtz R
Article: EUROPEAN JOURNAL OF NEUROLOGY. 2023;30(11):3430-3439
Gastrointestinal biopsy of normal mucosa or nonspecific inflammation and risk of neurodegenerative disease: Nationwide matched cohort study
Sun J; Ludvigsson JF; Roelstraete B; Pedersen NL; Pawitan Y; Wirdefeldt K; Fang F
Article: ANNALS OF NEUROLOGY. 2023;94(5):911-916
Risk of Parkinson's Disease in Celiac Disease: A Swedish Population-Based Study
Kang X; Ploner A; Roelstraete B; Ludvigsson JF; Wirdefeldt K
Article: ANNALS OF NEUROLOGY. 2023;93(5):1023-1028
β2-Adrenoreceptor Agonists, Montelukast, and Parkinson Disease Risk
Liu B; Svenningsson P; Ludvigsson JF; Lundholm C; Wallin J; Larsson H; Sjolander A; Williams DM; Pedersen NL; Wirdefeldt K
Article: MOVEMENT DISORDERS. 2023;38(4):604-615
Investigation of Shared Genetic Risk Factors Between Parkinson's Disease and Cancers
Sugier P-E; Lucotte EA; Domenighetti C; Law MH; Iles MM; Brown K; Amos C; McKay JD; Hung RJ; Karimi M; Bacq-Daian D; Boland-Auge A; Olaso R; Deleuze J-F; Lesueur F; Ostroumova E; Kesminiene A; de Vathaire F; Guenel P; Sreelatha AAK; Schulte C; Grover S; May P; Bobbili DR; Radivojkov-Blagojevic M; Lichtner P; Singleton AB; Hernandez DG; Edsall C; Mellick GD; Zimprich A; Pirker W; Rogaeva E; Lang AE; Koks S; Taba P; Lesage S; Brice A; Corvol J-C; Chartier-Harlin M-C; Mutez E; Brockmann K; Deutschlaender AB; Hadjigeorgiou GM; Dardiotis E; Stefanis L; Simitsi AM; Valente EM; Petrucci S; Straniero L; Zecchinelli A; Pezzoli G; Brighina L; Ferrarese C; Annesi G; Quattrone A; Gagliardi M; Matsuo H; Nakayama A; Hattori N; Nishioka K; Chung SJ; Kim YJ; Kolber P; van de Warrenburg BPC; Bloem BR; Aasly J; Toft M; Pihlstrom L; Guedes LC; Ferreira JJ; Bardien S; Carr J; Tolosa E; Ezquerra M; Pastor P; Diez-Fairen M; Wirdefeldt K; Pedersen N; Ran C; Belin AC; Puschmann A; Roedstroem EY; Clarke CE; Morrison KE; Tan M; Krainc D; Burbulla LF; Farrer MJ; Kruger R; Gasser T; Sharma M; Truong T; Elbaz A
Article: BRAIN COMMUNICATIONS. 2022;5(1):fcad002
Genetic overlap between Parkinson's disease and inflammatory bowel disease
Kang X; Ploner A; Wang Y; Ludvigsson JF; Williams DM; Pedersen NL; Wirdefeldt K
Article: MOVEMENT DISORDERS. 2022;37(9):1929-1937
The Interaction between HLA-DRB1 and Smoking in Parkinson's Disease Revisited
Domenighetti C; Douillard V; Sugier P-E; Sreelatha AAK; Schulte C; Grover S; May P; Bobbili DR; Radivojkov-Blagojevic M; Lichtner P; Singleton AB; Hernandez DG; Edsall C; Gourraud P-A; Mellick GD; Zimprich A; Pirker W; Rogaeva E; Lang AE; Koks S; Taba P; Lesage S; Brice A; Corvol J-C; Chartier-Harlin M-C; Mutez E; Brockmann K; Deutschlander AB; Hadjigeorgiou GM; Dardiotis E; Stefanis L; Simitsi AM; Valente EM; Petrucci S; Duga S; Straniero L; Zecchinelli A; Pezzoli G; Brighina L; Ferrarese C; Annesi G; Quattrone A; Gagliardi M; Matsuo H; Nakayama A; Hattori N; Nishioka K; Chung SJ; Kim YJ; Kolber P; van de Warrenburg BPC; Bloem BR; Aasly J; Toft M; Pihlstrom L; Correia Guedes L; Ferreira JJ; Bardien S; Carr J; Tolosa E; Ezquerra M; Pastor P; Diez-Fairen M; Wirdefeldt K; Pedersen NL; Ran C; Belin AC; Puschmann A; Ygland Rodstrom E; Clarke CE; Morrison KE; Tan M; KraincMD D; Burbulla LF; Farrer MJ; Kruger R; Gasser T; Sharma M; Vince N; Elbaz A
Article: PLOS MEDICINE. 2022;19(9):e1004092
Hospital-treated infections in early- and mid-life and risk of Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis: A nationwide nested case-control study in Sweden
Sun J; Ludvigsson JF; Ingre C; Piehl F; Wirdefeldt K; Zagai U; Ye W; Fang F
Article: NEUROLOGY. 2022;99(7):e698-e710
Genome-wide Association and Meta-analysis of Age at Onset in Parkinson Disease Evidence From the COURAGE-PD Consortium
Grover S; Kumar Sreelatha AA; Pihlstrom L; Domenighetti C; Schulte C; Sugier P-E; Radivojkov-Blagojevic M; Lichtner P; Mohamed O; Portugal B; Landoulsi Z; May P; Bobbili D; Edsall C; Bartusch F; Hanussek M; Krueger J; Hernandez DG; Blauwendraat C; Mellick GD; Zimprich A; Pirker W; Tan M; Rogaeva E; Lang A; Koks S; Taba P; Lesage S; Brice A; Corvol J-C; Chartier-Harlin M-C; Mutez E; Brockmann K; Deutschlaender AB; Hadjigeorgiou GM; Dardiotis E; Stefanis L; Simitsi AM; Valente EM; Petrucci S; Straniero L; Zecchinelli A; Pezzoli G; Brighina L; Ferrarese C; Annesi G; Quattrone A; Gagliardi M; Burbulla LF; Matsuo H; Kawamura Y; Hattori N; Nishioka K; Chung SJ; Kim YJ; Pavelka L; van de Warrenburg BPC; Bloem BR; Singleton AB; Aasly J; Toft M; Guedes LC; Ferreira JJ; Bardien S; Carr J; Tolosa E; Ezquerra M; Pastor P; Diez-Fairen M; Wirdefeldt K; Pedersen NL; Ran C; Belin AC; Puschmann A; Hellberg C; Clarke CE; Morrison KE; Krainc D; Farrer MJ; Kruger R; Elbaz A; Gasser T; Sharma M
Article: ANNALS OF NEUROLOGY. 2022;92(2):270-278
Polygenic Resilience Modulates the Penetrance of Parkinson Disease Genetic Risk Factors.
Liu H; Dehestani M; Blauwendraat C; Makarious MB; Leonard H; Kim JJ; Schulte C; Noyce A; Jacobs BM; Foote I; Sharma M; International Parkinson's Disease Genomics Consort; Nalls M; Singleton A; Gasser T; Bandres-Ciga S
Article: NEUROSCIENCE LETTERS. 2022;784:136767
Glucocerebrosidase variant T369M is not a risk factor for Parkinsons disease in Sweden
Ran C; Brodin L; Gellhaar S; Westerlund M; Fardell C; Nissbrandt H; Soderkvist P; Sydow O; Markaki I; Hertz E; Wirdefeldt K; Svenningsson P
Article: MOVEMENT DISORDERS. 2022;37(4):857-864
Dairy Intake and Parkinson's Disease: A Mendelian Randomization Study
Domenighetti C; Sugier P-E; Sreelatha AAK; Schulte C; Grover S; Mohamed O; Portugal B; May P; Bobbili DR; Radivojkov-Blagojevic M; Lichtner P; Singleton AB; Hernandez DG; Edsall C; Mellick GD; Zimprich A; Pirker W; Rogaeva E; Lang AE; Koks S; Taba P; Lesage S; Brice A; Corvol J-C; Chartier-Harlin M-C; Mutez E; Brockmann K; Deutschlaender AB; Hadjigeorgiou GM; Dardiotis E; Stefanis L; Simitsi AM; Valente EM; Petrucci S; Duga S; Straniero L; Zecchinelli A; Pezzoli G; Brighina L; Ferrarese C; Annesi G; Quattrone A; Gagliardi M; Matsuo H; Kawamura Y; Hattori N; Nishioka K; Chung SJ; Kim YJ; Kolber P; van de Warrenburg BPC; Bloem BR; Aasly J; Toft M; Pihlstrom L; Guedes LC; Ferreira JJ; Bardien S; Carr J; Tolosa E; Ezquerra M; Pastor P; Diez-Fairen M; Wirdefeldt K; Pedersen NL; Ran C; Belin AC; Puschmann A; Hellberg C; Clarke CE; Morrison KE; Tan M; Krainc D; Burbulla LF; Farrer MJ; Kruger R; Gasser T; Sharma M; Elbaz A
Article: EBIOMEDICINE. 2022;76:103824
Mendelian randomization study on the causal effects of tumor necrosis factor inhibition on coronary artery disease and ischemic stroke among the general population
Kang X; Jiao T; Wang H; Pernow J; Wirdefeldt K
Article: JOURNAL OF PARKINSON’S DISEASE. 2022;12(1):267-282
Mendelian Randomisation Study of Smoking, Alcohol, and Coffee Drinking in Relation to Parkinson's Disease
Domenighetti C; Sugier P-E; Sreelatha AAK; Schulte C; Grover S; Mohamed O; Portugal B; May P; Bobbili DR; Radivojkov-Blagojevic M; Lichtner P; Singleton AB; Hernandez DG; Edsall C; Mellick GD; Zimprich A; Pirker W; Rogaeva E; Lang AE; Koks S; Taba P; Lesage S; Brice A; Corvol J-C; Chartier-Harlin M-C; Mutez E; Brockmann K; Deutschlaender AB; Hadjigeorgiou GM; Dardiotis E; Stefanis L; Simitsi AM; Valente EM; Petrucci S; Duga S; Straniero L; Zecchinelli A; Pezzoli G; Brighina L; Ferrarese C; Annesi G; Quattrone A; Gagliardi M; Matsuo H; Kawamura Y; Hattori N; Nishioka K; Chung SJ; Kim YJ; Kolber P; van de Warrenburg BP; Bloem BR; Aasly J; Toft M; Pihlstrom L; Guedes LC; Ferreira JJ; Bardien S; Carr J; Tolosa E; Ezquerra M; Pastor P; Diez-Fairen M; Wirdefeldt K; Pedersen NL; Ran C; Belin AC; Puschmann A; Hellberg C; Clarke CE; Morrison KE; Tan M; Krainc D; Burbulla LF; Farrer MJ; Krueger R; Gasser T; Sharma M; Elbaz A
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY (EJE). 2021;36(10):1055-1064
Heart rate, intelligence in adolescence, and Parkinson's disease later in life
Longinetti E; Zhan Y; Sata M; Larsson H; D'Onofrio BM; Iso H; Wirdefeldt K; Fang F
Article: JOURNAL OF PARKINSON’S DISEASE. 2021;11(3):1325-1334
Neuroticism, Smoking, and the Risk of Parkinson's Disease
Sieurin J; Zhan Y; Pedersen NL; Wirdefeldt K
Article: MOVEMENT DISORDERS. 2021;36(8):1919-1926
Association between Microscopic Colitis and Parkinson's Disease in a Swedish Population
Kang X; Ploner A; Roelstraete B; Khalili H; Williams DM; Pedersen NL; Ludvigsson JF; Wirdefeldt K
Article: NEUROLOGY. 2021;96(12):e1672-e1679
Tumor Necrosis Factor Inhibition and Parkinson Disease A Mendelian Randomization Study
Kang X; Ploner A; Pedersen NL; Bandres-Ciga S; Noyce AJ; Wirdefeldt K; Williams DM
Article: NPJ PARKINSON'S DISEASE. 2021;7(1):5
Irritable bowel syndrome and Parkinson's disease risk: register-based studies
Liu B; Sjolander A; Pedersen NL; Ludvigsson JF; Chen H; Fang F; Wirdefeldt K
Article: EUROPEAN JOURNAL OF NEUROLOGY. 2020;27(11):2134-2141
Clostridium difficileinfection and risk of Parkinson's disease: a Swedish population-based cohort study
Kang X; Ploner A; Ludvigsson JF; Williams DM; Larsson H; Pedersen NL; Wirdefeldt K
Article: BRAIN COMMUNICATIONS. 2020;2(2):fcaa152
Creatinine and C-reactive protein in amyotrophic lateral sclerosis, multiple sclerosis and Parkinson's disease
Cui C; Sun J; Pawitan Y; Piehl F; Chen H; Ingre C; Wirdefeldt K; Evans M; Andersson J; Carrero J-J; Fang F
Article: JAMA NEUROLOGY. 2020;77(6):700-709
Association of Stress-Related Disorders With Subsequent Neurodegenerative Diseases
Song H; Sieurin J; Wirdefeldt K; Pedersen NL; Almqvist C; Larsson H; Valdimarsdottir UA; Fang F
Article: ALIMENTARY PHARMACOLOGY AND THERAPEUTICS. 2020;51(11):1022-1030
Vagotomy and subsequent risk of inflammatory bowel disease: a nationwide register-based matched cohort study
Liu B; Wanders A; Wirdefeldt K; Sjolander A; Sachs MC; Eberhardson M; Ye W; Ekbom A; Olen O; Ludvigsson JF
Article: FRONTIERS IN NEUROLOGY. 2020;11:548
Longitudinal Monitoring of Parkinson's Disease in Different Ethnic Cohorts: The DodoNA and LONG-PD Study
Markopoulou K; Aasly J; Chung SJ; Dardiotis E; Wirdefeldt K; Premkumar AP; Schoneburg B; Kartha N; Wilk G; Wei J; Simon KC; Tideman S; Epshteyn A; Hadsell B; Garduno L; Pham A; Frigerio R; Maraganore D
Article: FRONTIERS IN NEUROLOGY. 2020;11:510
Appendectomy, Tonsillectomy and Parkinson's Disease Risk: A Swedish Register-Based Study
Liu B; Fang F; Ye W; Wirdefeidt K
Article: NEUROLOGY. 2019;93(21):e1964-e1970
Family history increases the risk of late seizures after stroke
Eriksson H; Wirdefeldt K; Asberg S; Zelano J
Article: ACTA NEUROLOGICA SCANDINAVICA. 2019;140(5):342-349
Incidence of osmotic demyelination syndrome in Sweden: A nationwide study
Aegisdottir H; Cooray C; Wirdefeldt K; Piehl F; Sveinsson O
Article: PARKINSONISM AND RELATED DISORDERS. 2019;66:158-165
Low prevalence of known pathogenic mutations in dominant PD genes: A Swedish multicenter study
Puschmann A; Jimenez-Ferrer I; Lundblad-Andersson E; Martensson E; Hansson O; Odin P; Widner H; Brolin K; Mzezewa R; Kristensen J; Soller M; Rodstrom EY; Ross OA; Toft M; Breedveld GJ; Bonifati V; Brodin L; Zettergren A; Sydow O; Linder J; Wirdefeldt K; Svenningsson P; Nissbrandt H; Belin AC; Forsgren L; Swanberg M
Article: CIRCULATION RESEARCH. 2019;125(6):643-652
Lipids, Apolipoproteins, and the Risk of Parkinson Disease A Prospective Cohort Study and a Mendelian Randomization Analysis
Fang F; Zhan Y; Hammar N; Shen X; Wirdefeldt K; Walldius G; Mariosa D
Article: ANNALS OF INTERNAL MEDICINE. 2019;170(10):673-681
Relationship Between Poor Olfaction and Mortality Among Community-Dwelling Older Adults A Cohort Study
Liu B; Luo Z; Pinto JM; Shiroma EJ; Tranah GJ; Wirdefeldt K; Fang F; Harris TB; Chen H
Article: MOVEMENT DISORDERS. 2018;33(9):1456-1464
Occupational Stress and Risk for Parkinson's Disease: A Nationwide Cohort Study
Sieurin J; Andel R; Tillander A; Valdes EG; Pedersen NL; Wirdefeldt K
Article: NEUROLOGY. 2018;90(16):e1413-e1417
Body mass index, sitting time, and risk of Parkinson disease
Roos E; Grotta A; Yang F; Bellocco R; Ye W; Adami H-O; Wirdefeldt K; Lagerros YT
Article: MOVEMENT DISORDERS. 2017;32(11):1631-1636
Dietary Antioxidants and Risk of Parkinson's Disease in Two Population-Based Cohorts
Yang F; Wolk A; Hakansson N; Pedersen NL; Wirdefeldt K
Article: BRAIN. 2017;140(10):2653-2662
Migraine and risk of stroke: a national population-based twin study
Lantz M; Sieurin J; Sjolander A; Waldenlind E; Sjostrand C; Wirdefeldt K
Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2017;46(3):872-880
Moist smokeless tobacco (Snus) use and risk of Parkinson's disease
Yang F; Pedersen NL; Ye W; Liu Z; Norberg M; Forsgren L; Lagerros YT; Bellocco R; Alfredsson L; Knutsson A; Jansson J-H; Wennberg P; Galanti MR; Lager ACJ; Araghi M; Lundberg M; Magnusson C; Wirdefeldt K
Article: NEUROLOGY. 2017;88(21):1996-2002
Vagotomy and Parkinson disease A Swedish register-based matched-cohort study
Liu B; Fang F; Pedersen NL; Tillander A; Ludvigsson JF; Ekbom A; Svenningsson P; Chen H; Wirdefeldt K
Article: NEUROBIOLOGY OF AGING. 2017;49:217.e1-217.e4
Evaluation of the interaction between LRRK2 and PARK16 loci in determining risk of Parkinson's disease: analysis of a large multicenter study
Wang L; Heckman MG; Aasly JO; Annesi G; Bozi M; Chung SJ; Clarke C; Crosiers D; Eckstein G; Garraux G; Hadjigeorgiou GM; Hattori N; Jeon B; Kim YJ; Kubo M; Lesage S; Lin JJ; Lynch T; Lichtner P; Mellick GD; Mok V; Morrison KE; Quattrone A; Satake W; Silburn PA; Stefanis L; Stockton JD; Tan EK; Toda T; Brice A; Van Broeckhoven C; Uitti RJ; Wirdefeldt K; Wszolek Z; Xiromerisiou G; Maraganore DM; Gasser T; Krueger R; Farrer MJ; Ross OA; Sharma M
Article: PLOS ONE. 2017;12(5):e0173565
A KCNC3 mutation causes a neurodevelopmental, non-progressive SCA13 subtype associated with dominant negative effects and aberrant EGFR trafficking
Khare S; Nick JA; Zhang Y; Galeano K; Butler B; Khoshbouei H; Rayaprolu S; Hathorn T; Ranum LPW; Smithson L; Golde TE; Paucar M; Morse R; Raff M; Simon J; Ld MNE; Wirdefeldt K; Rincon-Limas DE; Lewis J; Kaczmarek LK; Fernandez-Funez P; Nick HS; Waters MF
Article: PARKINSON'S DISEASE. 2017;2017:4020198-7
Genetic Variations and mRNA Expression of NRF2 in Parkinson's Disease
Ran C; Wirdefeldt K; Brodin L; Ramezani M; Westerlund M; Xiang F; Anvret A; Willows T; Sydow O; Johansson A; Galter D; Svenningsson P; Belin AC
Article: NEUROBIOLOGY OF AGING. 2016;45:212.e5-212.e11
Strong association between glucocerebrosidase mutations and Parkinson's disease in Sweden
Ran C; Brodin L; Forsgren L; Westerlund M; Ramezani M; Gellhaar S; Xiang F; Fardell C; Nissbrandt H; Soderkvist P; Puschmann A; Ygland E; Olson L; Willows T; Johansson A; Sydow O; Wirdefeldt K; Galter D; Svenningsson P; Belin AC
Article: MEDICINE (UNITED KINGDOM). 2016;95(30):e4337
Socioeconomic status in relation to Parkinson's disease risk and mortality A population-based prospective study
Yang F; Johansson ALV; Pedersen NL; Fang F; Gatz M; Wirdefeldt K
Article: OPEN NEUROLOGY JOURNAL. 2016;10:25-29
No Association Between rs7077361 in ITGA8 and Parkinson's Disease in Sweden.
Ran C; Mehdi RN; Fardell C; Xiang F; Nissbrandt H; Sydow O; Wirdefeldt K; Belin AC
Article: NEUROLOGY. 2016;86(24):2271-2277
Depression in amyotrophic lateral sclerosis
Roos E; Mariosa D; Ingre C; Lundholm C; Wirdefeldt K; Roos PM; Fang F
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY (EJE). 2016;31(2):169-175
Personality traits and the risk for Parkinson disease: a prospective study
Sieurin J; Gustavsson P; Weibull CE; Feldman AL; Petzinger GM; Gatz M; Pedersen NL; Wirdefeldt K
Article: PLOS ONE. 2016;11(4):e0152841
Early-Life Factors and Risk of Parkinson's Disease: A Register-Based Cohort Study
Liu B; Chen H; Fang F; Tillander A; Wirdefeldt K
Article: NEUROLOGY. 2015;85(15):1283-1292
Large-scale assessment of polyglutamine repeat expansions in Parkinson disease
Wang L; Aasly JO; Annesi G; Bardien S; Bozi M; Brice A; Carr J; Chung SJ; Clarke C; Crosiers D; Deutschlaender A; Eckstein G; Farrer MJ; Goldwurm S; Garraux G; Hadjigeorgiou GM; Hicks AA; Hattori N; Klein C; Jeon B; Kim YJ; Lesage S; Lin J-J; Lynch T; Lichtner P; Lang AE; Mok V; Jasinska-Myga B; Mellick GD; Morrison KE; Opala G; Pihlstrom L; Pramstaller PP; Park SS; Quattrone A; Rogaeva E; Ross OA; Stefanis L; Stockton JD; Silburn PA; Theuns J; Tan EK; Tomiyama H; Toft M; Van Broeckhoven C; Uitti RJ; Wirdefeldt K; Wszolek Z; Xiromerisiou G; Yueh K-C; Zhao Y; Gasser T; Maraganore DM; Krueger R; Sharma M
Article: BRAIN. 2015;138(Pt 2):269-275
Physical activity and risk of Parkinson's disease in the Swedish National March Cohort
Yang F; Lagerros YT; Bellocco R; Adami H-O; Fang F; Pedersen NL; Wirdefeldt K
Article: PLOS ONE. 2015;10(4):e0122960
Is a Cancer Diagnosis Associated with Subsequent Risk of Transient Global Amnesia?
Zhu J; Lu D; Sveinsson O; Wirdefeldt K; Fall K; Piehl F; Valdimarsdottir U; Fang F
Article: NEUROEPIDEMIOLOGY. 2015;45(4):282-297
Methods in Neuroepidemiology Characterization of European Longitudinal Cohort Studies in Parkinson's Disease - Report of the JPND Working Group BioLoC-PD
Lerche S; Liepelt-Scarfone I; Alves G; Barone P; Behnke S; Ben-Shlomo Y; Berendse H; Burn D; Dodel R; Grosset D; Heinzel S; Hu M; Kasten M; Krueger R; Maetzler W; Moccia M; Mollenhauer B; Oertel W; Roeben B; Suenkel U; Walter U; Wirdefeldt K; Berg D
Article: NEUROLOGY. 2014;83(21):1906-1913
Global investigation and meta-analysis of the C9orf72 (G4C2)n repeat in Parkinson disease.
Theuns J; Verstraeten A; Sleegers K; Wauters E; Gijselinck I; Smolders S; Crosiers D; Corsmit E; Elinck E; Sharma M; Krüger R; Lesage S; Brice A; Chung SJ; Kim M-J; Kim YJ; Ross OA; Wszolek ZK; Rogaeva E; Xi Z; Lang AE; Klein C; Weissbach A; Mellick GD; Silburn PA; Hadjigeorgiou GM; Dardiotis E; Hattori N; Ogaki K; Tan E-K; Zhao Y; Aasly J; Valente EM; Petrucci S; Annesi G; Quattrone A; Ferrarese C; Brighina L; Deutschländer A; Puschmann A; Nilsson C; Garraux G; LeDoux MS; Pfeiffer RF; Boczarska-Jedynak M; Opala G; Maraganore DM; Engelborghs S; De Deyn PP; Cras P; Cruts M; Van Broeckhoven C; GEO-PD Consortium
Article: MOVEMENT DISORDERS. 2014;29(8):1053-1057
Alpha-Synuclein Repeat Variants and Survival in Parkinson's Disease
Chung SJ; Biernacka JM; Armasu SM; Anderson K; Frigerio R; Aasly JO; Annesi G; Bentivoglio AR; Brighina L; Chartier-Harlin M-C; Goldwurm S; Hadjigeorgiou G; Jasinska-Myga B; Jeon BS; Kim YJ; Krueger R; Lesage S; Markopoulou K; Mellick G; Morrison KE; Puschmann A; Tan E-K; Crosiers D; Theuns J; Van Broeckhoven C; Wirdefeldt K; Wszolek ZK; Elbaz A; Maraganore DM
Article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 2014;179(1):85-94
Parkinson's Disease and Cancer: A Register-based Family Study
Wirdefeldt K; Weibull CE; Chen H; Kamel F; Lundholm C; Fang F; Ye W
Article: PLOS ONE. 2014;9(9):e106676
Occupational Complexity and Risk of Parkinson's Disease
Valdes EG; Andel R; Sieurin J; Feldman AL; Edwards JD; Langstrom N; Gatz M; Wirdefeldt K
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY (EJE). 2014;29(1):49-56
Evidence for modest familial co-aggregation between dementia and parkinsonism
Feldman AL; Wirdefeldt K; Johansson ALV; Gatz M; Pedersen NL
Article: NEUROBIOLOGY OF AGING. 2014;35(1):266.e5-266.14
The protective effect of LRRK2 p.R1398H on risk of Parkinson's disease is independent of MAPT and SNCA variants
Heckman MG; Elbaz A; Soto-Ortolaza AI; Serie DJ; Aasly JO; Annesi G; Auburger G; Bacon JA; Boczarska-Jedynak M; Bozi M; Brighina L; Chartier-Harlin M-C; Dardiotism E; Destee A; Ferrarese C; Ferraris A; Fiske B; Gispert S; Hadjigeorgioum GM; Hattori N; Ioannidis JPA; Jasinska-Myga B; Jeon BS; Kim YJ; Klein C; Kruger R; Kyratzi E; Lin C-H; Lohmann K; Loriot M-A; Lynch T; Mellick GD; Mutez E; Opala G; Park SS; Petrucci S; Quattrone A; Sharma M; Silburn PA; Sohn YH; Stefanis L; Tadic V; Tomiyama H; Uitti RJ; Valente EM; Vassilatis DK; Vilarino-Guell C; White LR; Wirdefeldt K; Wszolek ZK; Wu R-M; Xiromerisiou G; Maraganore DM; Farrer MJ; Ross OA
Article: MOVEMENT DISORDERS. 2013;28(12):1740-1744
Population-specific Frequencies for LRRK2 Susceptibility Variants in the Genetic Epidemiology of Parkinson's Disease (GEO-PD) Consortium
Heckman MG; Soto-Ortolaza AI; Aasly JO; Abahuni N; Annesi G; Bacon JA; Bardien S; Bozi M; Brice A; Brighina L; Carr J; Chartier-Harlin M-C; Dardiotis E; Dickson DW; Diehl NN; Elbaz A; Ferrarese C; Fiske B; Gibson JM; Gibson R; Hadjigeorgiou GM; Hattori N; Ioannidis JPA; Boczarska-Jedynak M; Jasinska-Myga B; Jeon BS; Kim YJ; Klein C; Kruger R; Kyratzi E; Lesage S; Lin C-H; Lynch T; Maraganore DM; Mellick GD; Mutez E; Nilsson C; Opala G; Park SS; Petrucci S; Puschmann A; Quattrone A; Sharma M; Silburn PA; Sohn YH; Stefanis L; Tadic V; Theuns J; Tomiyama H; Uitti RJ; Valente EM; Van Broeckhoven C; van de Loo S; Vassilatis DK; Vilarino-Gueell C; White LR; Wirdefeldt K; Wszolek ZK; Wu R-M; Hentati F; Farrer MJ; Ross OA
Article: AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION. 2013;14(5-6):362-368
Amyotrophic lateral sclerosis and cancer: A register-based study in Sweden
Fang F; Al-Chalabi A; Ronnevi L-O; Turner MR; Wirdefeldt K; Kamel F; Ye W
Article: MOVEMENT DISORDERS. 2012;27(13):1632-1635
Head injury and Parkinson's disease: A population-based study
Fang F; Chen H; Feldman AL; Kamel F; Ye W; Wirdefeldt K
Article: JOURNAL OF MEDICAL GENETICS. 2012;49(11):721-726
A multi-centre clinico-genetic analysis of the VPS35 gene in Parkinson disease indicates reduced penetrance for disease-associated variants
Sharma M; Ioannidis JPA; Aasly JO; Annesi G; Brice A; Bertram L; Bozi M; Barcikowska M; Crosiers D; Clarke CE; Facheris MF; Farrer M; Garraux G; Gispert S; Auburger G; Vilarino-Guell C; Hadjigeorgiou GM; Hicks AA; Hattori N; Jeon BS; Jamrozik Z; Krygowska-Wajs A; Lesage S; Lill CM; Lin J-J; Lynch T; Lichtner P; Lang AE; Libioulle C; Murata M; Mok V; Jasinska-Myga B; Mellick GD; Morrison KE; Meitnger T; Zimprich A; Opala G; Pramstaller PP; Pichler I; Park SS; Quattrone A; Rogaeva E; Ross OA; Stefanis L; Stockton JD; Satake W; Silburn PA; Strom TM; Theuns J; Tan E-K; Toda T; Tomiyama H; Uitti RJ; Van Broeckhoven C; Wirdefeldt K; Wszolek Z; Xiromerisiou G; Yomono HS; Yueh K-C; Zhao Y; Gasser T; Maraganore D; Krueger R
Article: NEUROLOGY. 2012;79(7):659-667
Large-scale replication and heterogeneity in Parkinson disease genetic loci
Sharma M; Ioannidis JPA; Aasly JO; Annesi G; Brice A; Van Broeckhoven C; Bertram L; Bozi M; Crosiers D; Clarke C; Facheris M; Farrer M; Garraux G; Gispert S; Auburger G; Vilarino-Gueell C; Hadjigeorgiou GM; Hicks AA; Hattori N; Jeon B; Lesage S; Lill CM; Lin J-J; Lynch T; Lichtner P; Lang AE; Mok V; Jasinska-Myga B; Mellick GD; Morrison KE; Opala G; Pramstaller PP; Pichler I; Park SS; Quattrone A; Rogaeva E; Ross OA; Stefanis L; Stockton JD; Satake W; Silburn PA; Theuns J; Tan E-K; Toda T; Tomiyama H; Uitti RJ; Wirdefeldt K; Wszolek Z; Xiromerisiou G; Yueh K-C; Zhao Y; Gasser T; Maraganore D; Krueger R
Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2012;41(4):1042-1049
CNS infections, sepsis and risk of Parkinson's disease
Fang F; Wirdefeldt K; Jacks A; Kamel F; Ye W; Chen H
Article: NEUROEPIDEMIOLOGY. 2012;38(3):186-193
Accuracy and Sensitivity of Parkinsonian Disorder Diagnoses in Two Swedish National Health Registers
Feldman AL; Johansson ALV; Gatz M; Flensburg M; Petzinger GM; Widner H; Lew MF; Pedersen NL; Wirdefeldt K
Article: NEUROBIOLOGY OF AGING. 2011;32(11):2108.e1-2108.e5
Role of sepiapterin reductase gene at the PARK3 locus in Parkinson's disease
Sharma M; Maraganore DM; Ioannidis JPA; Riess O; Aasly JO; Annesi G; Abahuni N; Bentivoglio AR; Brice A; Van Broeckhoven C; Chartier-Harlin M-C; Destee A; Djarmati A; Elbaz A; Farrer M; Ferrarese C; Gibson JM; Gispert S; Hattori N; Jasinska-Myga B; Klein C; Lesage S; Lynch T; Lichtner P; Lambert J-C; Lang AE; Mellick GD; De Nigris F; Opala G; Quattrone A; Riva C; Rogaeva E; Ross OA; Satake W; Silburn PA; Theuns J; Toda T; Tomiyama H; Uitti RJ; Wirdefeldt K; Wszolek Z; Gasser T; Krueger R
Article: PARKINSONISM AND RELATED DISORDERS. 2011;17(9):677-682
Occupational exposure in Parkinsonian disorders: A 43-year prospective cohort study in men
Feldman AL; Johansson ALV; Nise G; Gatz M; Pedersen NL; Wirdefeldt K
Article: LANCET NEUROLOGY. 2011;10(10):898-908
Association of LRRK2 exonic variants with susceptibility to Parkinson's disease: a case-control study
Ross OA; Soto-Ortolaza AI; Heckman MG; Aasly JO; Abahuni N; Annesi G; Bacon JA; Bardien S; Bozi M; Brice A; Brighina L; Van Broeckhoven C; Carr J; Chartier-Harlin M-C; Dardiotis E; Dickson DW; Diehl NN; Elbaz A; Ferrarese C; Ferraris A; Fiske B; Gibson JM; Gibson R; Hadjigeorgiou GM; Hattori N; Ioannidis JPA; Jasinska-Myga B; Jeon BS; Kim YJ; Klein C; Kruger R; Kyratzi E; Lesage S; Lin C-H; Lynch T; Maraganore DM; Mellick GD; Mutez E; Nilsson C; Opala G; Park SS; Puschmann A; Quattrone A; Sharma M; Silburn PA; Sohn YH; Stefanis L; Tadic V; Theuns J; Tomiyama H; Uitti RJ; Valente EM; van de Loo S; Vassilatis DK; Vilarino-Gueell C; White LR; Wirdefeldt K; Wszolek ZK; Wu R-M; Farrer MJ
Article: NEUROBIOLOGY OF AGING. 2011;32(10):1923.e1-1923.e8
Heritability of Parkinson disease in Swedish twins: a longitudinal study
Wirdefeldt K; Gatza M; Reynolds CA; Prescott CA; Pedersen NL
Article: ANNALS OF NEUROLOGY. 2011;69(5):778-792
Independent and Joint Effects of the MAPT and SNCA Genes in Parkinson Disease
Elbaz A; Ross OA; Ioannidis JPA; Soto-Ortolaza AI; Moisan F; Aasly J; Annesi G; Bozi M; Brighina L; Chartier-Harlin M-C; Destee A; Ferrarese C; Ferraris A; Gibson JM; Gispert S; Hadjigeorgiou GM; Jasinska-Myga B; Klein C; Krueger R; Lambert J-C; Lohmann K; van de Loo S; Loriot M-A; Lynch T; Mellick GD; Mutez E; Nilsson C; Opala G; Puschmann A; Quattrone A; Sharma M; Silburn PA; Stefanis L; Uitti RJ; Valente EM; Vilarino-Gueell C; Wirdefeldt K; Wszolek ZK; Xiromerisiou G; Maraganore DM; Farrer MJ
Article: NEUROBIOLOGY OF AGING. 2011;32(3):548.e9-548.18
A large-scale genetic association study to evaluate the contribution of Omi/HtrA2 (PARK13) to Parkinson's disease
Krueger R; Sharma M; Riess O; Gasser T; Van Broeckhoven C; Theuns J; Aasly J; Annesi G; Bentivoglio AR; Brice A; Djarmati A; Elbaz A; Farrer M; Ferrarese C; Gibson JM; Hadjigeorgiou GM; Hattori N; Ioannidis JPA; Jasinska-Myga B; Klein C; Lambert J-C; Lesage S; Lin J-J; Lynch T; Mellick GD; de Nigris F; Opala G; Prigione A; Quattrone A; Ross OA; Satake W; Silburn PA; Tan EK; Toda T; Tomiyama H; Wirdefeldt K; Wszolek Z; Xiromerisiou G; Maraganore DM
Article: PLOS ONE. 2011;6(12):e29749
Infection of the Central Nervous System, Sepsis and Amyotrophic Lateral Sclerosis
Fang F; Chen H; Wirdefeldt K; Ronnevi L-O; Al-Chalabi A; Peters TL; Kamel F; Ye W
Article: AMERICAN JOURNAL OF MEDICAL GENETICS, PART B: NEUROPSYCHIATRIC GENETICS. 2010;153B(1):220-228
Non-Replication of Association for Six Polymorphisms From Meta-Analysis of Genome-Wide Association Studies of Parkinson's Disease: Large-Scale Collaborative Study
Evangelou E; Maraganore DM; Annesi G; Brijhina L; Brice A; Elbaz A; Ferrarese C; Hadjigeorgiou GM; Krueger R; Lambert J-C; Lesage S; Markopoulou K; Mellick GD; Meeus B; Pedersen NL; Quattrone A; Van Broeckhoven C; Sharma M; Silburn PA; Tan E-K; Wirdefeldt K; Ioannidis JPA
Article: NEUROBIOLOGY OF AGING. 2008;29(12):1765-1773
Complete ascertainment of Parkinson disease in the Swedish Twin Registry
Wirdefeldt K; Gatz M; Bakaysa SL; Fiske A; Flensburg M; Petzinger GM; Widner H; Lew MF; Welsh M; Pedersen NL
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2008;82(3):763-771
Phenotypically concordant and discordant monozygotic twins display different DNA copy-number-variation profiles
Bruder CEG; Piotrowski A; Gijsbers AACJ; Andersson R; Erickson S; de Stahl TD; Menzel U; Sandgren J; von Tell D; Poplawski A; Crowley M; Crasto C; Partridge EC; Tiwari H; Allison DB; Komorowski J; van Ommen G-JB; Boomsma DI; Pedersen NL; den Dunnen JT; Wirdefeldt K; Dumanski JP
Article: LANCET NEUROLOGY. 2006;5(11):917-923
Lack of replication of thirteen single-nucleotide polymorphisms implicated in Parkinson's disease:: a large-scale international study
Elbaz A; Nelson LM; Payami H; Ioannidis JPA; Fiske BK; Annesi G; Belin AC; Factor SA; Ferrarese C; Hadjigeorgiou GM; Higgins DS; Kawakami H; Krueger R; Marder KS; Mayeux RP; Mellick GD; Nutt JG; Ritz B; Samii A; Tanner CM; Van Broeckhoven C; Van Den Eeden SK; Wirdefeldt K; Zabetian CP; Dehem M; Montimurro JS; Southwick A; Myers RM; Trikalinos TA
Article: ANNALS OF NEUROLOGY. 2005;57(1):27-33
Risk and protective factors for Parkinson's disease: A study in Swedish twins
Wirdefeldt K; Gatz M; Pawitan Y; Pedersen NL
Article: NEUROLOGY. 2004;63(2):305-311
No evidence for heritability of Parkinson disease in Swedish twins
Wirdefeldt K; Gatz M; Schalling M; Pedersen NL
Article: BMC NEUROLOGY. 2003;3:6
A linkage study of candidate loci in familial Parkinson's Disease.
Wirdefeldt K; Burgess CE; Westerberg L; Payami H; Schalling M
Article: BRAIN RESEARCH. 2001;92(1-2):58-65
Expression of α-synuclein in the human brain:: relation to Lewy body disease
Wirdefeldt K; Bogdanovic N; Westerberg L; Payami H; Schalling M; Murdoch G
Article: NEUROSCIENCE LETTERS. 1999;272(2):140-142
Exclusion of dominant mutations within the FTDP-17 locus on chromosome 17 for Parkinson's disease
Zareparsi S; Wirdefeldt K; Burgess CE; Nutt J; Kramer P; Schalling M; Payami H
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Alla övriga publikationer

Letter: GUT. 2024;:gutjnl-2024-332352
Gastrointestinal syndromes in Parkinson's disease: risk factors or comorbidities?
Sun J; Yan D; Wirdefeldt K; Yao J; Ludvigsson JF
Letter: MOVEMENT DISORDERS. 2021;36(10):2453
Reply to: "Association between Microscopic Colitis and Parkinson's Disease in a Swedish Population".
Kang X; Ploner A; Roelstraete B; Khalili H; Williams DM; Pedersen NL; Ludvigsson JF; Wirdefeldt K
Letter: CNS DRUGS. 2016;30(10):1009-1010
Authors' Reply to Lambarth: "Levodopa-Carbidopa Intestinal Gel in Patients with Parkinson's Disease: A Systematic Review"
Wirdefeldt K; Odin P; Nyholm D
Letter: MOVEMENT DISORDERS. 2016;31(9):1422-1423
Reduced incidence of Parkinson's disease after dipeptidyl peptidase-4 inhibitorsA nationwide case-control study
Svenningsson P; Wirdefeldt K; Yin L; Fang F; Markaki I; Efendic S; Ludvigsson JF
Review: CNS DRUGS. 2016;30(5):381-404
Levodopa-Carbidopa Intestinal Gel in Patients with Parkinson's Disease: A Systematic Review
Wirdefeldt K; Odin P; Nyholm D
Review: FRONTIERS IN AGING NEUROSCIENCE. 2016;8:147
Prodromal Markers in Parkinson's Disease: Limitations in Longitudinal Studies and Lessons Learned
Heinzel S; Roeben B; Ben-Shlomo Y; Lerche S; Alves G; Barone P; Behnke S; Berendse HW; Bloem BR; Burn D; Dodel R; Grosset DG; Hu M; Kasten M; Krueger R; Moccia M; Mollenhauer B; Oertel W; Suenkel U; Walter U; Wirdefeldt K; Liepelt-Scarfone I; Maetzler W; Berg D
Editorial comment: FRONTIERS IN AGING NEUROSCIENCE. 2016;8:121
Aiming for Study Comparability in Parkinson's Disease: Proposal for a Modular Set of Biomarker Assessments to be Used in Longitudinal Studies
Lerche S; Heinzel S; Alves G; Barone P; Behnke S; Ben-Shlomo Y; Berendse H; Bloem BR; Burn D; Dodel R; Grosset DG; Hipp G; Hu MT; Kasten M; Kruger R; Liepelt-Scarfone I; Maetzler W; Moccia M; Mollenhauer B; Oertel W; Roeben B; Walter U; Wirdefeldt K; Berg D
Review: NEUROEPIDEMIOLOGY. 2014;42(2):69-80
Familial Coaggregation of Alzheimer's Disease and Parkinson's Disease: Systematic Review and Meta-Analysis
Feldman AL; Johansson ALV; Lambert PC; Sieurin J; Yang F; Pedersen NL; Wirdefeldt K
Corrigendum: JOURNAL OF MEDICAL GENETICS. 2013;50(3):202
A multi-centre clinico-genetic analysis of the VPS35 gene in Parkinson disease indicates reduced penetrance for disease-associated variants (vol 49, pg 721, 2012)
Sharma M; Ioannidis JP; Aasly JO; Annesi G; Brice A; Bertram L; Bozi M; Barcikowska M; Crosiers D; Clarke CE; Facheris MF; Farrer M; Garraux G; Gispert S; Auburger G; Vilarino-Gueell C; Hadjigeorgiou GM; Hicks AA; Hattori N; Jeon BS; Jamrozik Z; Krygowska-Wajs A; Lesage S; Lill CM; Lin JJ; Lynch T; Lichtner P; Lang AE; Libioulle C; Murata M; Mok V; Jasinska-Myga B; Mellick GD; Morrison KE; Meitnger T; Zimprich A; Opala G; Pramstaller PP; Pichler I; Park SS; Quattrone A; Rogaeva E; Ross OA; Stefanis L; Stockton JD; Satake W; Silburn PA; Strom TM; Theuns J; Tan EK; Toda T; Tomiyama H; Uitti RJ; Van Broeckhoven C; Wirdefeldt K; Wszolek Z; Xiromerisiou G; Yomono HS; Yueh KC; Zhao Y; Gasser T; Maraganore D; Krueger R
Review: EUROPEAN JOURNAL OF EPIDEMIOLOGY (EJE). 2011;26:S1-58
Epidemiology and etiology of Parkinson's disease: a review of the evidence
Wirdefeldt K; Adami H-O; Cole P; Trichopoulos D; Mandel J
Letter: NEUROLOGY. 2005;64(5):932
No evidence for heritability of Parkinson disease in Swedish twins - Repl
Pedersen NL; Wirdefeldt K; Gatz M; Schalling M
Thesis / dissertation: 2004
Studies of genetic and environmental influences on Parkinson’s disease
Wirdefeldt, Karin

Anställningar

Adjungerad Professor, Medicinsk epidemiologi och biostatistik, Karolinska Institutet, 2023-2026
Adjungerad Professor, Klinisk neurovetenskap, Karolinska Institutet, 2023-2026

Examina och utbildning

Docent, Neuroepidemiologi, Karolinska Institutet, 2015
MEDICINE DOKTORSEXAMEN, Institutionen för medicinsk epidemiologi och biostatistik, Karolinska Institutet, 2004
Läkarexamen, Karolinska Institutet, 1996

Handledare

Sara Licaj
Katalin Vincze

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Examina och utbildning

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