Johan Lindberg

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Artiklar

Journal article: JOURNAL OF CLINICAL ONCOLOGY. 2025;43(4_SUPPL):lba125
Low-dose aspirin to reduce recurrence rate in colorectal cancer patients with PI3K pathway alterations: 3-year results from a randomized placebo-controlled trial.
Martling A; Lindberg J; Myrberg IH; Nilbert M; Mayrhofer M; Gronberg H; Glimelius B; ALASCCA TSG
Article: CANCERS. 2024;16(22):3816
Prospective Screening of Cancer Syndromes in Patients with Mesenchymal Tumors
Ofverholm I; Lin Y; Mondini J; Hardingz J; Braenstroem R; Tsagkozis P; Wirta V; Gellerbring A; Lindberg J; Chellappa V; Mayrhofer M; Haglund C; Haglund de Flon F; Wallander K
Article: NATURE MEDICINE. 2024;30(11):3291-3302
Androgen receptor pathway inhibitors and taxanes in metastatic prostate cancer: an outcome-adaptive randomized platform trial
De Laere B; Crippa A; Discacciati A; Larsson B; Persson M; Johansson S; D'hondt S; Bergstrom R; Chellappa V; Mayrhofer M; Banijamali M; Kotsalaynen A; Schelstraete C; Vanwelkenhuyzen JP; Hjalm-Eriksson M; Pettersson L; Ullen A; Lumen N; Enblad G; Thellenberg Karlsson C; Janes E; Sandzen J; Schatteman P; Vigmostad M; Olsson M; Ghysel C; Sautois B; De Roock W; Van Bruwaene S; Anden M; Verbiene I; De Maeseneer D; Everaert E; Darras J; Aksnessether BY; Luyten D; Strijbos M; Mortezavi A; Oldenburg J; Ost P; Eklund M; Gronberg H; Lindberg J
Journal article: ANNALS OF ONCOLOGY. 2024;35:s991-s992
PSA trajectories and prediction of time to no-longer clinically benefitting in metastatic castration-resistant prostate cancer: Insights from the ProBio trial
Broer L; Oldenburg J; Mortezavi A; Lindberg J; Discacciati A; Karlsson CT; Ullen A; Janes E; Enblad G; Pettersson L; Vigmostad MN; Hjalm-Eriksson ME; Olsson M; Schatteman P; Ghysel C; De Laere B; Gronberg H; Ost P; Eklund M; Crippa A
Journal article: ANNALS OF ONCOLOGY. 2024;35:s978
Efficacy of carboplatin in patients with metastatic castration-resistant prostate cancer: Results from the biomarker-driven, randomised, outcome-adaptive ProBio trial
Kristiansen A; Sautois B; Crippa A; Mortezavi A; Discacciati A; Karlsson CT; Ullen A; Janes E; Enblad G; Oldenburg J; Sandzen J; Vigmostad MN; Hjalm-Eriksson ME; De Laere B; Strijbos MH; Ghysel C; Lindberg J; Eklund M; Ost P; Gronberg H
Journal article: ANNALS OF ONCOLOGY. 2024;35:s987
Health-related quality of life outcomes of androgen receptor pathway inhibitors versus taxanes versus standard of care in metastatic castration-resistant prostate cancer: Results from the ProBio trial
Bultijnck R; Strijbos MH; Mortezavi A; Lindberg J; Discacciati A; Karlsson CT; Ullen A; Janes E; Enblad G; Oldenburg J; Sautois B; Hjalm-Eriksson ME; Haugnes HS; Schatteman P; Ghysel C; De Laere B; Eklund M; Gronberg H; Ost P; Crippa A
Journal article: ANNALS OF ONCOLOGY. 2024;35:s980
Prognostic value of circulating tumour DNA fraction in metastatic castration-resistant prostate cancer: Insights from the ProBio trial
Crippa A; Mortezavi A; Discacciati A; Karlsson CT; Strijbos MH; Janes E; Enblad G; Sautois B; Ullen A; Stenner-Liewen F; Hjalm-Eriksson ME; De Maeseneer DJ; Schatteman P; Ghysel C; Oldenburg J; Lindberg J; Ost P; Eklund M; Gronberg H; De Laere B
Journal article: BRITISH JOURNAL OF SURGERY. 2024;111:znae175.055
Reflex CRC Initiative - Advancing Colorectal Cancer Care through Comprehensive Genetic Testing
Pappas C; Olauson H; Haglund F; Lindberg J; Beergrehn C; Tham E; Sjovall A
Article: CLINICAL CANCER RESEARCH. 2024;30(12):2647-2658
Comprehensive Genomic Profiling Alters Clinical Diagnoses in a Significant Fraction of Tumors Suspicious of Sarcoma
Ofverholm I; Wallander K; Haglund C; Chellappa V; Wejde J; Gellerbring A; Wirta V; Renevey A; Caceres E; Tsagkozis P; Mayrhofer M; Papakonstantinou A; Linder-Stragliotto C; Branstrom R; Larsson O; Lindberg J; Lin Y; de Flon FH
Article: NATURE COMMUNICATIONS. 2024;15(1):1828
Prediction of plasma ctDNA fraction and prognostic implications of liquid biopsy in advanced prostate cancer
Fonseca NM; Maurice-Dror C; Herberts C; Tu W; Fan W; Murtha AJ; Kollmannsberger C; Kwan EM; Parekh K; Schonlau E; Bernales CQ; Donnellan G; Ng SWS; Sumiyoshi T; Vergidis J; Noonan K; Finch DL; Zulfiqar M; Miller S; Parimi S; Lavoie J-M; Hardy E; Soleimani M; Nappi L; Eigl BJ; Kollmannsberger C; Taavitsainen S; Nykter M; Tolmeijer SH; Boerrigter E; Mehra N; van Erp NP; De Laere B; Lindberg J; Gronberg H; Khalaf DJ; Annala M; Chi KN; Wyatt AW
Journal article: NATURE MEDICINE. 2024;30(11)
Androgen receptor pathway inhibitors and taxanes in metastatic prostate cancer: an outcome-adaptive randomized platform trial
De Laere B; Crippa A; Discacciati A; Larsson B; Persson M; Johansson S; D'hondt S; Bergstrom R; Chellappa V; Mayrhofer M; Banijamali M; Kotsalaynen A; Schelstraete C; Vanwelkenhuyzen JP; Hjalm-Eriksson M; Pettersson L; Ullen A; Lumen N; Enblad G; Thellenberg Karlsson C; Janes E; Sandzen J; Schatteman P; Vigmostad M; Olsson M; Ghysel C; Sautois B; De Roock W; Van Bruwaene S; Anden M; Verbiene I; De Maeseneer D; Everaert E; Darras J; Aksnessether BY; Luyten D; Strijbos M; Mortezavi A; Oldenburg J; Ost P; Eklund M; Gronberg H; Lindberg J
Article: EUROPEAN UROLOGY OPEN SCIENCE. 2023;53:63-66
AR and PI3K Genomic Profiling of Cell-free DNA Can Identify Poor Responders to Lutetium-177-PSMA Among Patients with Metastatic Castration-resistant Prostate Cancer
Vanwelkenhuyzen J; Van Bos E; Van Bruwaene S; Lesage K; Maes A; Ustmert S; Lavent F; Beels L; Groenberg H; Ost P; Lindberg J; De Laere B
Article: CLINICAL CHEMISTRY. 2023;69(4):386-398
Prognostic Value of Low-Pass Whole Genome Sequencing of Circulating Tumor DNA in Metastatic Castration-Resistant Prostate Cancer
Norgaard M; Bjerre MT; Fredsoe J; Vang S; Jensen JB; De Laere B; Groenberg H; Borre M; Lindberg J; Sorensen KD
Article: ANNALS OF ONCOLOGY. 2022;33(8):750-768
ESMO recommendations on the use of circulating tumour DNA assays for patients with cancer: a report from the ESMO Precision Medicine Working Group
Pascual J; Attard G; Bidard F-C; Curigliano G; De Mattos-Arruda L; Diehn M; Italiano A; Lindberg J; Merker JD; Montagut C; Normanno N; Pantel K; Pentheroudakis G; Popat S; Reis-Filho JS; Tie J; Seoane J; Tarazona N; Yoshino T; Turner NC
Article: ELIFE. 2022;11:e71569
Unsupervised detection of fragment length signatures of circulating tumor DNA using non-negative matrix factorization
Renaud G; Norgaard M; Lindberg J; Gronberg H; De Laere B; Jensen JB; Borre M; Andersen CL; Sorensen KD; Maretty L; Besenbacher S
Article: ISCIENCE. 2022;25(7):104663
Using deep learning to detect patients at risk for prostate cancer despite benign biopsies
Liu B; Wang Y; Weitz P; Lindberg J; Hartman J; Wang W; Egevad L; Gronberg H; Eklund M; Rantalainen M
Article: BIOINFORMATICS. 2022;38(13):3462-3469
Transcriptome-wide prediction of prostate cancer gene expression from histopathology images using co-expression-based convolutional neural networks
Weitz P; Wang Y; Kartasalo K; Egevad L; Lindberg J; Gronberg H; Eklund M; Rantalainen M
Article: PROSTATE. 2022;82(5):576-583
Ductal and acinar components of mixed prostatic adenocarcinoma frequently have a common clonal origin
Lindh C; Samaratunga H; Delahunt B; Bergstrom R; Chellappa V; Yaxley J; Lindberg J; Egevad L
Article: NATURE CANCER. 2022;3(2):251-261
The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology
Tamborero D; Dienstmann R; Rachid MH; Boekel J; Lopez-Fernandez A; Jonsson M; Razzak A; Brana I; De Petris L; Yachnin J; Baird RD; Loriot Y; Massard C; Martin-Romano P; Opdam F; Schlenk RF; Vernieri C; Masucci M; Villalobos X; Chavarria E; Balmana J; Apolone G; Caldas C; Bergh J; Ernberg I; Frohling S; Garralda E; Karlsson C; Tabernero J; Voest E; Rodon J; Lehtio J
Article: FRONTIERS IN GENETICS. 2022;13:820493
Fusion Gene Detection Using Whole-Exome Sequencing Data in Cancer Patients
Deng W; Murugan S; Lindberg J; Chellappa V; Shen X; Pawitan Y; Vu TN
Article: CANCERS. 2021;13(7):1588
Increased Pathway Complexity Is a Prognostic Biomarker in Metastatic Castration-Resistant Prostate Cancer
De Laere B; Crippa A; Mortezavi A; Ghysel C; Rajan P; Eklund M; Wyatt A; Dirix L; Ost P; Gronberg H; Lindberg J
Article: BLOOD ADVANCES. 2021;5(4):1003-1016
Challenging conventional karyotyping by next-generation karyotyping in 281 intensively treated patients with AML
Mareschal S; Palau A; Lindberg J; Ruminy P; Nilsson C; Bengtzen S; Engvall M; Eriksson A; Neddermeyer A; Marchand V; Jansson M; Bjorklund M; Jardin F; Rantalainen M; Lennartsson A; Cavelier L; Gronberg H; Lehmann S
Article: TRIALS. 2020;21(1):579
The ProBio trial: molecular biomarkers for advancing personalized treatment decision in patients with metastatic castration-resistant prostate cancer
Crippa A; De Laere B; Discacciati A; Larsson B; Connor JT; Gabriel EE; Thellenberg C; Janes E; Enblad G; Ullen A; Hjalm-Eriksson M; Oldenburg J; Ost P; Lindberg J; Eklund M; Gronberg H
Article: BLOOD CANCER JOURNAL. 2020;10(6):67
Integrated transcriptomic and genomic analysis improves prediction of complete remission and survival in elderly patients with acute myeloid leukemia
Osterroos A; Bjorklund M; Eriksson A; Lindberg J; Nilsson C; Mareschal S; Rantalainen M; Gronberg H; Lehmann S
Article: GENES. 2020;11(3):E314-314
Inherited DNA Repair Gene Mutations in Men with Lethal Prostate Cancer
Rantapero T; Wahlfors T; Kahler A; Hultman C; Lindberg J; Tammela TLJ; Nykter M; Schleutker J; Wiklund F
Article: LANCET ONCOLOGY. 2020;21(2):222-232
Artificial intelligence for diagnosis and grading of prostate cancer in biopsies: a population-based, diagnostic study
Strom P; Kartasalo K; Olsson H; Solorzano L; Delahunt B; Berney DM; Bostwick DG; Evans AJ; Grignon DJ; Humphrey PA; Iczkowski KA; Kench JG; Kristiansen G; van der Kwast TH; Leite KRM; McKenney JK; Oxley J; Pan C-C; Samaratunga H; Srigley JR; Takahashi H; Tsuzuki T; Varma M; Zhou M; Lindberg J; Lindskog C; Ruusuvuori P; Wahlby C; Gronberg H; Rantalainen M; Egevad L; Eklund M
Article: PROSTATE. 2019;79(8):920-928
Somatic alterations detected in diagnostic prostate biopsies provide an inadequate representation of multifocal prostate cancer
Kristiansen A; Bergstrom R; Delahunt B; Samaratunga H; Gudjonsdottir J; Gronberg H; Egevad L; Lindberg J
Article: CLINICAL CANCER RESEARCH. 2019;25(6):1766-1773
TP53 Outperforms Other Androgen Receptor Biomarkers to Predict Abiraterone or Enzalutamide Outcome in Metastatic Castration-Resistant Prostate Cancer
De Laere B; Oeyen S; Mayrhofer M; Whitington T; van Dam P-J; Van Oyen P; Ghysel C; Ampe J; Ost P; Demey W; Hoekx L; Schrijvers D; Brouwers B; Lybaert W; Everaert EG; De Maeseneer D; Strijbos M; Bols A; Fransis K; Beije N; de Kruijff IE; van Dam V; Brouwer A; Goossens D; Heyrman L; Van den Eynden GG; Rutten A; Del Favero J; Rantalainen M; Rajan P; Sleijfer S; Ullen A; Yachnin J; Gronberg H; Van Laere SJ; Lindberg J; Dirix LY
Article: PLOS ONE. 2019;14(6):e0218280
Are Prostate Specific-Antigen (PSA) and age associated with the risk of ISUP Grade 1 prostate cancer? Results from 72 996 individual biopsy cores in 6 083 men from the Stockholm3 study
Palsdottir T; Nordstrom T; Aly M; Lindberg J; Clements M; Egevad L; Gronberg H; Eklund M
Article: GENOME MEDICINE. 2018;10(1):85
Cell-free DNA profiling of metastatic prostate cancer reveals microsatellite instability, structural rearrangements and clonal hematopoiesis
Mayrhofer M; De Laere B; Whitington T; Van Oyen P; Ghysel C; Ampe J; Ost P; Demey W; Hoekx L; Schrijvers D; Brouwers B; Lybaert W; Everaert E; De Maeseneer D; Strijbos M; Bols A; Fransis K; Oeyen S; van Dam P-J; Van den Eynden G; Rutten A; Aly M; Nordstrom T; Van Laere S; Rantalainen M; Rajan P; Egevad L; Ullen A; Yachnin J; Dirix L; Gronberg H; Lindberg J
Article: JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2018;110(10):1094-1101
Development and Validation of a Novel RNA Sequencing-Based Prognostic Score for Acute Myeloid Leukemia
Wang M; Lindberg J; Klevebring D; Nilsson C; Lehmann S; Gronberg H; Rantalainen M
Article: EUROPEAN UROLOGY FOCUS. 2018;4(5):707-710
The Stockholm-3 (STHLM3) Model can Improve Prostate Cancer Diagnostics in Men Aged 50-69 yr Compared with Current Prostate Cancer Testing
Eklund M; Nordstrom T; Aly M; Adolfsson J; Wiklund P; Brandberg Y; Thompson J; Wiklund F; Lindberg J; Presti JC; StLezin M; Clements M; Egevad L; Gronberg H
Article: JOURNAL OF HEMATOLOGY & ONCOLOGY. 2018;11(1):52
Expression levels of long non-coding RNAs are prognostic for AML outcome
Mer AS; Lindberg J; Nilsson C; Klevebring D; Wang M; Gronberg H; Lehmann S; Rantalainen M
Article: HISTOPATHOLOGY. 2018;72(3):481-489
A novel technique for biobanking of large sections of radical prostatectomy specimens
Lindh C; Delahunt B; Samaratunga H; Yaxley J; Gudjonsdottir J; Clements M; Lindberg J; Egevad L
Article: JOURNAL OF CLINICAL INVESTIGATION. 2018;128(1):341-358
Differential impact of RB status on E2F1 reprogramming in human cancer
McNair C; Xu K; Mandigo AC; Benelli M; Leiby B; Rodrigues D; Lindberg J; Gronberg H; Crespo M; De laere B; Dirix L; Visakorpi T; Li F; Feng FY; de Bono J; Demichelis F; Rubin MA; Brown M; Knudsen KE
Article: BMC CANCER. 2017;17(1):802
Intra-tumor heterogeneity in breast cancer has limited impact on transcriptomic-based molecular profiling
Karthik G-M; Rantalainen M; Stalhammar G; Lovrot J; Ullah I; Alkodsi A; Ma R; Wedlund L; Lindberg J; Frisell J; Bergh J; Hartman J
Article: HUMAN PATHOLOGY. 2017;69:1-7
Genetic profile of ductal adenocarcinoma of the prostate
Seipel AH; Whitington T; Delahunt B; Samaratunga H; Mayrhofer M; Wiklund P; Gronberg H; Lindberg J; Egevad L
Article: MOLECULAR ONCOLOGY. 2017;11(10):1413-1429
Bioinformatory-assisted analysis of next-generation sequencing data for precision medicine in pancreatic cancer
Malgerud L; Lindberg J; Wirta V; Gustafsson-Liljefors M; Karimi M; Moro CF; Stecker K; Picker A; Huelsewig C; Stein M; Bohnert R; Del Chiaro M; Haas SL; Heuchel RL; Permert J; Maeurer MJ; Brock S; Verbeke CS; Engstrand L; Jackson DB; Gronberg H; Lohr J-M
Article: LEUKEMIA. 2017;31(10):2029-2036
Validation of risk stratification models in acute myeloid leukemia using sequencing-based molecular profiling
Wang M; Lindberg J; Klevebring D; Nilsson C; Mer AS; Rantalainen M; Lehmann S; Gronberg H
Article: EUROPEAN UROLOGY. 2017;72(2):192-200
Comprehensive Profiling of the Androgen Receptor in Liquid Biopsies from Castration-resistant Prostate Cancer Reveals Novel Intra-AR Structural Variation and Splice Variant Expression Patterns
De laere B; van Dam P-J; Whitington T; Mayrhofer M; Diaz EH; Van den Eynden G; Vandebroek J; Del-Favero J; Van Laere S; Dirix L; Gronberg H; Lindberg J
Article: EUROPEAN UROLOGY. 2017;72(1):22-31
Translating a Prognostic DNA Genomic Classifier into the Clinic: Retrospective Validation in 563 Localized Prostate Tumors
Lalonde E; Alkallas R; Chua MLK; Fraser M; Haider S; Meng A; Zheng J; Yao CQ; Picard V; Orain M; Hovington H; Murgic J; Berlin A; Lacombe L; Bergeron A; Fradet Y; Tetu B; Lindberg J; Egevad L; Gronberg H; Ross-Adams H; Lamb AD; Halim S; Dunning MJ; Neal DE; Pintilie M; van der Kwast T; Bristow RG; Boutros PC
Article: CLINICAL CANCER RESEARCH. 2017;23(10):2584-2592
Molecular Differences between Screen-Detected and Interval Breast Cancers Are Largely Explained by PAM50 Subtypes
Li J; Ivansson E; Klevebring D; Tobin NP; Lindstrom LS; Holm J; Prochazka G; Cristando C; Palmgren J; Tornberg S; Humphreys K; Hartman J; Frisell J; Rantalainen M; Lindberg J; Hall P; Bergh J; Gronberg H; Czene K
Article: SCIENTIFIC REPORTS. 2016;6:38037
Sequencing-based breast cancer diagnostics as an alternative to routine biomarkers.
Rantalainen M; Klevebring D; Lindberg J; Ivansson E; Rosin G; Kis L; Celebioglu F; Fredriksson I; Czene K; Frisell J; Hartman J; Bergh J; Grönberg H
Article: MOLECULAR ONCOLOGY. 2016;10(6):825-837
Large-scale evaluation of SLC18A2 in prostate cancer reveals diagnostic and prognostic biomarker potential at three molecular levels
Haldrup C; Lynnerup A-S; Storebjerg TM; Vang S; Wild P; Visakorpi T; Arsov C; Schulz WA; Lindberg J; Groenberg H; Egevad L; Borre M; Orntoft TF; Hoyer S; Sorensen KD
Article: BREAST CANCER RESEARCH. 2016;18(1):48
Determining breast cancer histological grade from RNA-sequencing data.
Wang M; Klevebring D; Lindberg J; Czene K; Grönberg H; Rantalainen M
Article: NATURE GENETICS. 2016;48(4):387-397
Gene regulatory mechanisms underpinning prostate cancer susceptibility
Whitington T; Gao P; Song W; Ross-Adams H; Lamb AD; Yang Y; Svezia I; Klevebring D; Mills IG; Karlsson R; Halim S; Dunning MJ; Egevad L; Warren AY; Neal DE; Gronberg H; Lindberg J; Wei G-H; Wiklund F
Article: PLOS ONE. 2016;11(12):e0168153
The In Vitro Stability of Circulating Tumour DNA
Diaz EH; Yachnin J; Gronberg H; Lindberg J
Article: LANCET ONCOLOGY. 2015;16(16):1667-1676
Prostate cancer screening in men aged 50-69 years (STHLM3): a prospective population-based diagnostic study
Gronberg H; Adolfsson J; Aly M; Nordstrom T; Wiklund P; Brandberg Y; Thompson J; Wiklund F; Lindberg J; Clements M; Egevad L; Eklund M
Article: EBIOMEDICINE. 2015;2(9):1133-1144
Integration of copy number and transcriptomics provides risk stratification in prostate cancer: A discovery and validation cohort study
Ross-Adams H; Lamb AD; Dunning MJ; Halim S; Lindberg J; Massie CM; Egevad LA; Russell R; Ramos-Montoya A; Vowler SL; Sharma NL; Kay J; Whitaker H; Clark J; Hurst R; Gnanapragasam VJ; Shah NC; Warren AY; Cooper CS; Lynch AG; Stark R; Mills IG; Groenberg H; Neal DE
Article: SCIENTIFIC REPORTS. 2015;5:13426
The RNA-binding protein Sam68 regulates expression and transcription function of the androgen receptor splice variant AR-V7
Stockley J; Markert E; Zhou Y; Robson CN; Elliott DJ; Lindberg J; Leung HY; Rajan P
Article: BREAST CANCER RESEARCH AND TREATMENT. 2015;151(2):319-324
Exome sequencing of contralateral breast cancer identifies metastatic disease.
Klevebring D; Lindberg J; Rockberg J; Hilliges C; Hall P; Sandberg M; Czene K
Article: EUROPEAN UROLOGY. 2015;67(5):819-822
Tracking the Origin of Metastatic Prostate Cancer
Lindberg J; Kristiansen A; Wiklund P; Gronberg H; Egevad L
Article: NEW ENGLAND JOURNAL OF MEDICINE. 2014;371(26):2477-2487
Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence
Genovese G; Kaehler AK; Handsaker RE; Lindberg J; Rose SA; Bakhoum SF; Chambert K; Mick E; Neale BM; Fromer M; Purcell SM; Svantesson O; Landen M; Hoeglund M; Lehmann S; Gabriel SB; Moran JL; Lander ES; Sullivan PF; Sklar P; Groenberg H; Hultman CM; McCarroll SA
Article: VIRCHOWS ARCHIV. 2014;465(5):559-565
Immunohistochemical profile of ductal adenocarcinoma of the prostate
Seipel AH; Samaratunga H; Delahunt B; Wiklund F; Wiklund P; Lindberg J; Gronberg H; Egevad L
Article: BREAST CANCER RESEARCH. 2014;16(4):R72
Sequencing of breast cancer stem cell populations indicates a dynamic conversion between differentiation states in vivo
Klevebring D; Rosin G; Ma R; Lindberg J; Czene K; Kere J; Fredriksson I; Bergh J; Hartman J
Article: CLINICAL CANCER RESEARCH. 2014;20(8):2169-2181
Hypermethylation of the GABRE∼miR-452∼miR-224 Promoter in Prostate Cancer Predicts Biochemical Recurrence after Radical Prostatectomy
Kristensen H; Haldrup C; Strand S; Mundbjerg K; Mortensen MM; Thorsen K; Ostenfeld MS; Wild PJ; Arsov C; Goering W; Visakorpi T; Egevad L; Lindberg J; Groenberg H; Hoyer S; Borre M; Orntoft TF; Sorensen KD
Article: NATURE GENETICS. 2014;46(2):126-135
A prostate cancer susceptibility allele at 6q22 increases RFX6 expression by modulating HOXB13 chromatin binding
Huang Q; Whitington T; Gao P; Lindberg JF; Yang Y; Sun J; Vaisanen M-R; Szulkin R; Annala M; Yan J; Egevad LA; Zhang K; Lin R; Jolma A; Nykter M; Manninen A; Wiklund F; Vaarala MH; Visakorpi T; Xu J; Taipale J; Wei G-H
Article: PLOS ONE. 2014;9(8):e104417
Evaluation of Exome Sequencing to Estimate Tumor Burden in Plasma
Klevebring D; Neiman M; Sundling S; Eriksson L; Ramqvist ED; Celebioglu F; Czene K; Hall P; Egevad L; Groenberg H; Lindberg J
Article: CANCER. 2013;119(13):2405-2412
Genetic markers associated with early cancer-specific mortality following prostatectomy
Liu W; Xie CC; Thomas CY; Kim S-T; Lindberg J; Egevad L; Wang Z; Zhang Z; Sun J; Sun J; Koty PP; Kader AK; Cramer SD; Bova GS; Zheng SL; Groenberg H; Isaacs WB; Xu J
Article: EUROPEAN UROLOGY. 2013;63(4):702-708
The Mitochondrial and Autosomal Mutation Landscapes of Prostate Cancer
Lindberg J; Mills IG; Klevebring D; Liu W; Neiman M; Xu J; Wikstrom P; Wiklund P; Wiklund F; Egevad L; Gronberg H
Article: EUROPEAN UROLOGY. 2013;63(2):347-353
Exome Sequencing of Prostate Cancer Supports the Hypothesis of Independent Tumour Origins
Lindberg J; Klevebring D; Liu W; Neiman M; Xu J; Wiklund P; Wiklund F; Mills IG; Egevad L; Gronberg H
Article: ONCOGENE. 2012;31(35):3939-3948
Identification of novel CHD1-associated collaborative alterations of genomic structure and functional assessment of CHD1 in prostate cancer
Liu W; Lindberg J; Sui G; Luo J; Egevad L; Li T; Xie C; Wan M; Kim S-T; Wang Z; Turner AR; Zhang Z; Feng J; Yan Y; Sun J; Bova GS; Ewing CM; Yan G; Gielzak M; Cramer SD; Vessella RL; Zheng SL; Gronberg H; Isaacs WB; Xu J
Article: CYTOKINE. 2012;57(3):406-416
Signaling pathways involved in the regulation of TNFα-induced toll-like receptor 2 expression in human gingival fibroblasts
Davanian H; Bage T; Lindberg J; Lundeberg J; Concha HQ; Chen MS; Yucel-Lindberg T
Article: PLOS ONE. 2012;7(11):e48616
Library Preparation and Multiplex Capture for Massive Parallel Sequencing Applications Made Efficient and Easy
Neiman M; Sundling S; Gronberg H; Hall P; Czene K; Lindberg J; Klevebring D
Article: PLOS ONE. 2012;7(10):e48455
Identification of New Differentially Methylated Genes That Have Potential Functional Consequences in Prostate Cancer
Kim JW; Kim S-T; Turner AR; Young T; Smith S; Liu W; Lindberg J; Egevad L; Gronberg H; Isaacs WB; Xu J
Article: PLOS ONE. 2010;5(6):e11310
The Gene Expression Profile in the Synovium as a Predictor of the Clinical Response to Infliximab Treatment in Rheumatoid Arthritis
Lindberg J; Wijbrandts CA; van Baarsen LG; Nader G; Klareskog L; Catrina A; Thurlings R; Vervoordeldonk M; Lundeberg J; Tak PP
Article: BMC GENOMICS. 2010;11:241
Signal pathways JNK and NF-κB, identified by global gene expression profiling, are involved in regulation of TNFα-induced mPGES-1 and COX-2 expression in gingival fibroblasts
Bage T; Lindberg J; Lundeberg J; Modeer T; Yucel-Lindberg T
Article: ARTHRITIS & RHEUMATOLOGY. 2010;62(1):44-52
Antibodies to Several Citrullinated Antigens Are Enriched in the Joints of Rheumatoid Arthritis Patients
Snir O; Widhe M; Hermansson M; von Spee C; Lindberg J; Hensen S; Lundberg K; Engstrom A; Venables PJW; Toes REM; Holmdahl R; Klareskog L; Malmstrom V
Article: ANNALS OF THE RHEUMATIC DISEASES. 2009;68(5):736-743
Multiple antibody reactivities to citrullinated antigens in sera from patients with rheumatoid arthritis: association with HLA-DRB1 alleles
Snir O; Widhe M; von Spee C; Lindberg J; Padyukov L; Lundberg K; Engstrom A; Venables PJ; Lundeberg J; Holmdahl R; Klareskog L; Malmstrom V
Article: JOURNAL OF NEUROENDOCRINOLOGY. 2009;21(3):208-216
Extremely Different Behaviours in High and Low Body Weight Lines of Chicken are Associated with Differential Expression of Genes Involved in Neuronal Plasticity
Ka S; Lindberg J; Stromstedt L; Fitzsimmons C; Lindqvist N; Lundeberg J; Siegel PB; Andersson L; Hallbook F
Article: JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY. 2009;2009:396808
Automation of cDNA Synthesis and Labelling Improves Reproducibility
Klevebring D; Gry M; Lindberg J; Eidefors A; Lundeberg J
Article: ARTHRITIS RESEARCH & THERAPY. 2008;10(2):R33
Systemic TNF blockade does not modulate synovial expression of the pro-inflammatory mediator HMGB1 in rheumatoid arthritis patients - a prospective clinical study
Sundberg E; Grundtman C; Klint EAF; Lindberg J; Ernestam S; Ulfgren A-K; Harris HE; Andersson U
Article: BMC GENOMICS. 2007;8:208
Differential gene expression in femoral bone from red junglefowl and domestic chicken, differing for bone phenotypic traits
Rubin C-J; Lindberg J; Fitzsimmons C; Savolainen P; Jensen P; Lundeberg J; Andersson L; Kindmark A
Article: PLOS ONE. 2007;2(4):e364
Transmission of Stress-Induced Learning Impairment and Associated Brain Gene Expression from Parents to Offspring in Chickens
Lindqvist C; Janczak AM; Natt D; Baranowska I; Lindqvist N; Wichman A; Lundeberg J; Lindberg J; Torjesen PA; Jensen P
Article: MOLECULAR & CELLULAR PROTEOMICS. 2007;6(1):125-132
Determination of binding specificities in highly multiplexed bead-based assays for antibody proteomics
Schwenk JM; Lindberg J; Sundberg M; Uhlen M; Nilsson P
Article: ARTHRITIS RESEARCH & THERAPY. 2006;8(2):r47
Variability in synovial inflammation in rheumatoid arthritis investigated by microarray technology
Lindberg J; af Klint E; Ulfgren A-K; Stark A; Andersson T; Nilsson P; Klareskog L; Lundeberg J
Article: ARTHRITIS RESEARCH & THERAPY. 2006;8(6):R179
Effect of infliximab on mRNA expression profiles in synovial tissue of rheumatoid arthritis patients
Lindberg J; af Klint E; Catrina AI; Nilsson P; Klareskog L; Ulfgren A-K; Lundeberg J
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Corrigendum: NATURE MEDICINE. 2024;30(11):3381
Androgen receptor pathway inhibitors and taxanes in metastatic prostate cancer: an outcome-adaptive randomized platform trial (vol 30, pg 3291, 2024)
De Laere B; Crippa A; Discacciati A; Larsson B; Persson M; Johansson S; D'hondt S; Bergstrom R; Chellappa V; Mayrhofer M; Banijamali M; Kotsalaynen A; Schelstraete C; Vanwelkenhuyzen JP; Hjaelm-Eriksson M; Pettersson L; Ullen A; Lumen N; Enblad G; Karlsson CT; Jaenes E; Sandzen J; Schatteman P; Vigmostad MN; Olsson M; Ghysel C; Sautois B; De Roock W; Van Bruwaene S; Anden M; Verbiene I; De Maeseneer D; Everaert E; Darras J; Aksnessether BY; Luyten D; Strijbos M; Mortezavi A; Oldenburg J; Ost P; Eklund M; Gronberg H; Lindberg J
Preprint: MEDRXIV. 2024
Sensitive detection of copy number alterations in samples with low circulating tumor DNA fraction
Mayrhofer M; Bergström R; Chellappa V; Kotsalaynen A; Murugan S; Crippa A; De Laere B; Urtishak K; Sorensen KD; Garg K; Singh U; Eklund M; Grönberg H; Lindberg J
Editorial comment: EUROPEAN UROLOGY FOCUS. 2022;8(6):1617-1621
Clinical Trial Protocol for ProBio: An Outcome-adaptive and Randomised Multiarm Biomarker-driven Study in Patients with Metastatic Prostate Cancer
De laere B; Crippa A; Discacciati A; Larsson B; Oldenburg J; Mortezavi A; Ost P; Eklund M; Lindberg J; Gronberg H
Review: ACTA ONCOLOGICA. 2022;61(4):523-530
Circulating tumor DNA (ctDNA) in adjuvant therapy of early stage colon cancer: current status and future perspectives
Merk C; Martling A; Lindberg J; Benhaim L; Taieb J; Lind P
Review: EUROPEAN UROLOGY FOCUS. 2021;7(4):687-691
Artificial Intelligence for Diagnosis and Gleason Grading of Prostate Cancer in Biopsies-Current Status and Next Steps
Kartasalo K; Bulten W; Delahunt B; Chen P-HC; Pinckaers H; Olsson H; Ji X; Mulliqi N; Samaratunga H; Tsuzuki T; Lindberg J; Rantalainen M; Wahlby C; Litjens G; Ruusuvuori P; Egevad L; Eklund M
Preprint: ARXIV. 2021
Using deep learning to detect patients at risk for prostate cancer despite benign biopsies
Liu B; Wang Y; Weitz P; Lindberg J; Hartman J; Egevad L; Grönberg H; Eklund M; Rantalainen M
Preprint: BIORXIV. 2021
Discovering fragment length signatures of circulating tumor DNA using Non-negative Matrix Factorization
Renaud G; Nørgaard M; Lindberg J; Grönberg H; De Laere B; Jensen JB; Borre M; Andersen CL; Sørensen KD; Maretty L; Besenbacher S
Letter: JOURNAL OF CLINICAL ONCOLOGY. 2019;37(24):2181-2182
Has the PROPHECY of AR-V7 Been Fulfilled?
De Laere B; Ost P; Gronberg H; Lindberg J
Letter: JAMA ONCOLOGY. 2019;5(7):1060-1062
Androgen Receptor Burden and Poor Response to Abiraterone or Enzalutamide in TP53 Wild-Type Metastatic Castration-Resistant Prostate Cancer
De Laere B; Rajan P; Gronberg H; Dirix L; Lindberg J; Mayrhofer M; Whitington T; van Dam P-J; Van Oyen P; Ghysel C; Ampe J; Ost P; Demey W; Hoela L; Schrijvers D; Brouwers B; Lybaert W; Everaert E; De Maeseneer D; Strijbos M; Bols A; Fransis K; Beije N; de Kruijff I; van Dam V; Brouwer A; Goossens D; Heyrman L; Van den Eynden G; Rutten A; Del Favero J; Rantalainen M; Sleijfer S; Ullen A; Yachnin J; Van Laere S; De laere L; Develter T; Vantieghem S; Herman S; Coifs G; Lamotte V; Boumans A; Baitar A; Haeck R; Wallays G
Editorial comment: EUROPEAN UROLOGY. 2018;74(6):739-740
Towards Next-generation Urine-based Prostate Cancer Risk Stratification
Nordstrom T; Lindberg J; Eklund M
Corrigendum: EBIOMEDICINE. 2017;17:238
Integration of Copy Number and Transcriptomics Provides Risk Stratification in Prostate Cancer: A Discovery and Validation Cohort Study (vol 2, pg 1133, 2015)
Ross-Adams H; Lamb AD; Dunning MJ; Halim S; Lindberg J; Massie CM; Egevad LA; Russell R; Ramos-Montoya A; Vowler SL; Sharma NL; Kay J; Whitaker H; Clarkh J; Hurst R; Gnanapragasam VJ; Shah NC; Warren AY; Cooper CS; Lynch AG; Stark R; Mills IG; Gronberg H; Neal DE
Review: GENOMICS. 2010;95(1):1-6
The plasticity of the mammalian transcriptome
Lindberg J; Lundeberg J

Forskningsbidrag

Icke-invasiv blodbaserad biopsi för spridd prostatacancer
Prostatacancerförbundet
1 February 2024 - 1 February 2026
Lindberg, Johan Fredrik – Liquid biopsies in metastatic prostate cancer
Swedish Cancer Society
1 January 2024
Icke-invasiv blodbaserad biopsi för spridd prostatacancer.
Radiumhemmets forskningsfonder
1 January 2024 - 1 January 2026
Detection of inactivating genomic alterations in BRCA1/2 and establishment of a tissue selection algorithm to maximise the probability of successful screening.
AstraZeneca
1 January 2024 - 31 December 2026
ProBio: An outcome-adaptive and randomised multi-arm biomarker driven study in patients with metastatic prostate cancer
Swedish Research Council
1 January 2022 - 31 December 2025
Artificial intelligence, game-based learning, and DNA-profiling to differentiate benign from malignant ovarian tumours, and to predict the prognosis in women with ovarian cancer.
Swedish Research Council
1 January 2021 - 31 December 2023
Clinical implementation of the Individualized Prostate Cancer Diagnosis Pipeline
Swedish Research Council
1 January 2021 - 31 December 2024
Lindberg, Johan Fredrik – Liquid biopsies in localized prostate cancer
Swedish Cancer Society
1 January 2021
CITCCA-Circulating Tumour DNA in Colorectal Cancer- a pilot study
Swedish Research Council
1 January 2020 - 31 December 2020
The prostate cancer image epidemiology project: development and validation of model-based histopathology
Swedish Research Council
1 January 2019 - 31 December 2022
Clinical implementation of the Individualized Prostate Cancer Diagnosis Pipeline
Swedish Research Council
1 January 2018 - 31 December 2020
ProBio II – An adaptive and randomized multi-arm biomarker driven phase 2 study in men with castrate resistant prostate cancer (CRPC)
Swedish Research Council
1 December 2017 - 31 December 2020
Genomics of prostate cancer: From gene identification to clinical applications
Swedish Research Council
1 January 2013 - 31 December 2016
Genetic susceptibility of prostate cancer: From gene identification to clinical applications
Swedish Research Council
1 January 2010 - 31 December 2012

Anställningar

Senior Forskare, Medicinsk epidemiologi och biostatistik, Karolinska Institutet, 2022-

Handledning

Cecilia Merk, 2022

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