Johan Högberg

Johan Högberg

Professor Emeritus
E-postadress: johan.hogberg@ki.se
Telefon: +46852487783
Besöksadress: Nobels väg 13, 17177 Stockholm
Postadress: C6 Institutet för miljömedicin, C6 Biokemisk toxikologi Stenius, 171 77 Stockholm
Del av:

Om mig

  • Ongoing research projects:
    - Gender differences in carcinogenesis (supported by Formas)
    - Low-dose genotoxic effects of crystalline silica particles (supported
    by AFA).

    - New type of DNA damage induced by chrystalline siliuca particles: does anti-androgenic carcinogens increase men´s sensitivity ti silica? (supported by Forte 2025 - 2027).

     

Forskningsbeskrivning

  • Recent selected publications:
    Approaches for the setting of occupational exposure limits (OELs) for
    carcinogens. [1]
    *Högberg J*, Järnberg J.Crit Rev Toxicol. 2023 Dec;53(3):131-167. doi:
    10.1080/10408444.2023.2218887. Epub 2023 Jun 27.PMID: 37366107 Review
    ATX-LPA-Dependent Nuclear Translocation of Endonuclease G in Respiratory
    Epithelial Cells: A New Mode Action for DNA Damage Induced by Crystalline
    Silica Particles. [2]
    Zheng H, Stenius U, *Högberg J.*Cancers (Basel). 2023 Jan 30;15(3):865.
    doi: 10.3390/cancers15030865.PMID: 36765823.
    Application of Text Mining in Risk Assessment of Chemical Mixtures: A Case
    Study of Polycyclic Aromatic Hydrocarbons (PAHs). [3]
    Ali I, Dreij K, Baker S, *Högberg J*, Korhonen A, Stenius U.Environ Health
    Perspect. 2021 Jun;129(6):67008. doi: 10.1289/EHP6702. Epub 2021 Jun
    24.PMID: 34165340.
    Crystalline silica particles induce DNA damage in respiratory epithelium by
    ATX secretion and Rac1 activation. [4]
    Wu R, *Högberg J*, Adner M, Stenius U, Zheng H.Biochem Biophys Res Commun.
    2021 Apr 9;548:91-97. doi: 10.1016/j.bbrc.2021.02.020. Epub 2021 Feb
    23.PMID: 33636640.
    Crystalline silica particles cause rapid NLRP3-dependent mitochondrial
    depolarization and DNA damage in airway epithelial cells. [5]
    Wu R, *Högberg J*, Adner M, Ramos-Ramírez P, Stenius U, Zheng H.Part Fibre
    Toxicol. 2020 Aug 10;17(1):39. doi:
    10.1186/s12989-020-00370-2.PMID: 32778128.
    [1] https://pubmed-ncbi-nlm-nih-gov.proxy.kib.ki.se/37366107/
    [2] https://pubmed-ncbi-nlm-nih-gov.proxy.kib.ki.se/36765823/
    [3] https://pubmed-ncbi-nlm-nih-gov.proxy.kib.ki.se/34165340/
    [4] https://pubmed-ncbi-nlm-nih-gov.proxy.kib.ki.se/33636640/
    [5] https://pubmed-ncbi-nlm-nih-gov.proxy.kib.ki.se/32778128/

Artiklar

Alla övriga publikationer

Forskningsbidrag

Anställningar

  • Professor Emeritus, Institutet för miljömedicin, Karolinska Institutet, 2025-2028
  • Professor, Institutet för miljömedicin, Karolinska Institutet, 2021-2025
  • Professor, Senior, Institutet för miljömedicin, Karolinska Institutet, 2011-2020
  • Professor, Institutet för miljömedicin, Karolinska Institutet, 2002-2010

Examina och utbildning

  • Docent, Rättsmedicin, Karolinska Institutet, 1978

Nyheter från KI

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