Christopher Sundling
Senior Forskare | Docent
E-postadress: christopher.sundling@ki.se
Besöksadress: BioClinicum J7:20, 17164 Solna
Postadress: K2 Medicin, Solna, K2 Infekt Färnet A Sundling C, 171 77 Stockholm
Utvalda publikationer
- Article: IMMUNITY. 2025;58(8):2120-2136.e5Lautenbach MJ; Wyss K; Yman V; Foroogh F; Satarvandi D; Mousavian Z; Sonden K; Wang J; Alvez MB; Bergstrom S; Nilsson P; Edfors F; Brodin P; Uhlen M; Sundling C; Farnert A
- Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2024;54(8):e2350736Kleberg L; Courey-Ghaouzi A-D; Lautenbach MJ; Farnert A; Sundling C
- Article: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES. 2024;141:106984Kallenius G; Correia-Neves M; Sundling C
- Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2024;54(4):e2350784Sundling C; Yman V; Mousavian Z; Angenendt S; Foroogh F; von Horn E; Lautenbach MJ; Grunewald J; Faernert A; Sonden K
- Review: EUROPEAN JOURNAL OF IMMUNOLOGY. 2023;53(12):e2350485Mousavian Z; Kaellenius G; Sundling C
- Article: ISCIENCE. 2022;25(12):105652Mousavian Z; Folkesson E; Froberg G; Foroogh F; Correia-Neves M; Bruchfeld J; Kallenius G; Sundling C
- Article: CELL REPORTS. 2022;39(3):110709Lautenbach MJ; Yman V; Silva CS; Kadri N; Broumou I; Chan S; Angenendt S; Sonden K; Plaza DF; Farnert A; Sundling C
Artiklar
- Article: JOURNAL OF INFECTIOUS DISEASES. 2025;232(1):e78-e88Folkesson E; Froberg G; Sundling C; Schon T; Sodersten E; Bruchfeld J
- Article: IMMUNITY. 2025;58(6):1586-1597.e5Grace PS; Peters JM; Sixsmith J; Lu R; Irvine EB; Luedeman C; Fenderson BA; Vickers A; Slein MD; McKitrick T; Wei M-H; Cummings RD; Wallace A; Cavacini LA; Choudhary A; Proulx MK; Sundling C; Kallenius G; Reljic R; Ernst JD; Casadevall A; Locht C; Pinter A; Sassetti CM; Bryson BD; Fortune SM; Alter G
- Journal article: JOURNAL OF INFECTIOUS DISEASES. 2025;:jiaf260Folkesson E; Froberg G; Sundling C; Schon T; Sodersten E; Bruchfeld J
- Article: FRONTIERS IN IMMUNOLOGY. 2024;15:1501700Zerebinski J; Margerie L; Han NS; Moll M; Ritvos M; Jahnmatz P; Ahlborg N; Ngasala B; Rooth I; Sjoeberg R; Sundling C; Yman V; Faernert A; Plaza DF
- Journal article: BIORXIV. 2024;:2024.10.07.617070Grace PS; Peters JM; Sixsmith J; Lu R; Luedeman C; Fenderson BA; Vickers A; Slein MD; Irvine EB; McKitrick T; Wei M-H; Cummings RD; Wallace A; Cavacini LA; Choudhary A; Proulx MK; Sundling C; Källenius G; Reljic R; Ernst JD; Casadevall A; Locht C; Pinter A; Sasseti CM; Bryson BD; Fortune SM; Alter G
- Article: FRONTIERS IN ENDOCRINOLOGY. 2024;15:1454006Bradley F; Stern A; Boger MF; Mousavian Z; Dethlefsen O; Kaldhusdal V; Lajoie J; Omollo K; Bergstrom S; Manberg A; Nilsson P; Kimani J; Burgener AD; Tjernlund A; Sundling C; Fowke KR; Broliden K
- Article: PLOS MEDICINE. 2024;21(9):e1004452Calderwood CJ; Marambire ET; Larsson L; Banze D; Mfinanga A; Nhamuave C; Appalarowthu T; Mugava M; Ribeiro J; Towo PE; Madziva K; Dixon J; Held K; Minja LT; Mutsvangwa J; Khosa C; Heinrich N; Fielding K; Kranzer K; ERASE-TB consortium
- Journal article: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES. 2024;141:106993Goletti D; Al-Abri S; Migliori GB; Arlehamn CL; Haldar P; Sundling C; da Costa C; To KW; Martineau AR; Petersen E; Zumla A; Lee SS
- Journal article: PLOS ONE. 2024;19(1):e0297828Cantera JL; Lillis LM; Peck RB; Moreau E; Schouten JA; Davis P; Zheng RB; Lowary TL; Drain PK; Andama A; Pinter A; Kawasaki M; Källenius G; Sundling C; Dobos KM; Flores D; Chatterjee D; Murphy E; Halas OR; Boyle DS
- Article: CELL REPORTS: METHODS. 2023;3(9):100574Plaza DF; Zerebinski J; Broumou I; Lautenbach MJ; Ngasala B; Sundling C; Farnert A
- Article: NATURE COMMUNICATIONS. 2023;14(1):2164Yu M; Charles A; Cagigi A; Christ W; osterberg B; Falck-Jones S; Azizmohammadi L; ahlberg E; Falck-Jones R; Svensson J; Nie M; Warnqvist A; Hellgren F; Lenart K; Arcoverde Cerveira R; Ols S; Lindgren G; Lin A; Maecker H; Bell M; Johansson N; Albert J; Sundling C; Czarnewski P; Klingstroem J; Faernert A; Lore K; Smed-Soerensen A
- Article: IMMUNITY. 2023;56(3):635-652.e6Corcoran M; Chernyshev M; Mandolesi M; Narang S; Kaduk M; Ye K; Sundling C; Farnert A; Kreslavsky T; Bernhardsson C; Larena M; Jakobsson M; Hedestam GBK
- Article: JOURNAL OF INFECTIOUS DISEASES. 2022;226(8):1428-1440Gibbs A; Healy K; Kaldhusdal V; Sundling C; Franzen-Boger M; Edfeldt G; Buggert M; Lajoie J; Fowke KR; Kimani J; Kwon DS; Andersson S; Sandberg JK; Broliden K; Davanian H; Chen MS; Tjernlund A
- Article: PLOS ONE. 2022;17(9):e0274415Cantera JL; Lillis LM; Peck RB; Moreau E; Schouten JA; Davis P; Drain PK; Andama A; Pinter A; Kawasaki M; Kallenius G; Sundling C; Dobos KM; Flores D; Chatterjee D; Murphy E; Halas OR; Boyle DS
- Article: BMJ OPEN. 2022;12(7):e060985Marambire ET; Banze D; Mfinanga A; Mutsvangwa J; Mbunda TD; Ntinginya NE; Celso K; Kallenius G; Calderwood CJ; Geldmacher C; Held K; Appalarowthu T; Riess F; Panzner U; Heinrich N; Kranzer K
- Article: FRONTIERS IN IMMUNOLOGY. 2022;13:799306Jahnmatz P; Nyabundi D; Sundling C; Widman L; Mwacharo J; Musyoki J; Otieno E; Ahlborg N; Bejon P; Ndungu FM; Farnert A
- Article: NATURE COMMUNICATIONS. 2022;13(1):331Yman V; Tuju J; White MT; Kamuyu G; Mwai K; Kibinge N; Asghar M; Sundling C; Sonden K; Murungi L; Kiboi D; Kimathi R; Chege T; Chepsat E; Kiyuka P; Nyamako L; Osier FHA; Farnert A
- Article: FRONTIERS IN IMMUNOLOGY. 2021;12:727300Silva CS; Sundling C; Folkesson E; Froberg G; Nobrega C; Canto-Gomes J; Chambers BJ; Lakshmikanth T; Brodin P; Bruchfeld J; Nigou J; Correia-Neves M; Kallenius G
- Article: IMMUNITY. 2021;54(5):988-1001.e5Sundling C; Lau AWY; Bourne K; Young C; Laurianto C; Hermes JR; Menzies RJ; Butt D; Krautler NJ; Zahra D; Suan D; Brink R
- Article: FRONTIERS IN IMMUNOLOGY. 2021;11:619398Jahnmatz P; Sundling C; Yman V; Widman L; Asghar M; Sonden K; Stenstrom C; Smedman C; Ndungu F; Ahlborg N; Farnert A
- Article: PLOS ONE. 2021;16(1):e0245431Ronnberg C; Lugaajju A; Nyman A; Hammar U; Bottai M; Lautenbach MJ; Sundling C; Kironde F; Persson KEM
- Article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2021;10(7):e1313Kerkman PF; Dernstedt A; Tadala L; Mittler E; Dannborg M; Sundling C; Maleki KT; Tauriainen J; Tuiskunen-Back A; Wigren Bystrom J; Ocaya P; Thunberg T; Jangra RK; Roman-Sosa G; Guardado-Calvo P; Rey FA; Klingstrom J; Chandran K; Puhar A; Ahlm C; Forsell MNE
- Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2020;481:112792Silva MH; Lepzien R; Ols S; Dahlberg B; Grunewald J; Lore K; Smed-Sorensen A; Correia-Neves M; Empadinhas N; Farnert A; Kallenius G; Sundling C
- Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2020;478:112715Jahnmatz P; Sundling C; Makower B; Sonden K; Farnert A; Ahlborg N
- Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2020;217(2):e20191155Phad GE; Pushparaj P; Tran K; Dubrovskaya V; Adori M; Martinez-Murillo P; Bernat NV; Singh S; Dionne G; O'Dell S; Bhullar K; Narang S; Sorini C; Villablanca EJ; Sundling C; Murrell B; Mascola JR; Shapiro L; Pancera M; Martin M; Corcoran M; Wyatt RT; Hedestam GBK
- Article: JCI INSIGHT. 2019;4(9):126492Sundling C; Ronnberg C; Yman V; Asghar M; Jahnmatz P; Lakshmikanth T; Chen Y; Mikes J; Forsell MN; Sonden K; Achour A; Brodin P; Persson KEM; Farnert A
- Article: BMC MEDICINE. 2019;17(1):22Yman V; White MT; Asghar M; Sundling C; Sonden K; Draper SJ; Osier FHA; Farnert A
- Article: JCI INSIGHT. 2018;3(5):97018Cheng HD; Grimm SK; Gilman MSA; Gwom LC; Sok D; Sundling C; Donofrio G; Hedestam GBK; Bonsignori M; Haynes BF; Lahey TP; Maro I; von Reyn CF; Gorny MK; Zolla-Pazner S; Walker BD; Alter G; Burton DR; Robb ML; Krebs SJ; Seaman MS; Bailey-Kellogg C; Ackerman ME
- Article: CELL. 2017;169(5):891-904.e15Zhao X; Howell KA; He S; Brannan JM; Wec AZ; Davidson E; Turner HL; Chiang C-I; Lei L; Fels JM; Vu H; Shulenin S; Turonis AN; Kuehne AI; Liu G; Ta M; Wang Y; Sundling C; Xiao Y; Spence JS; Doranz BJ; Holtsberg FW; Ward AB; Chandran K; Dye JM; Qiu X; Li Y; Aman MJ
- Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2017;214(5):1259-1267Kraeutler NJ; Suan D; Butt D; Bourne K; Hermes JR; Chan TD; Sundling C; Kaplan W; Schofield P; Jackson J; Basten A; Christ D; Brink R
- Journal article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2016;5(8):e96Sundling C; Sandgren K
- Article: FRONTIERS IN IMMUNOLOGY. 2016;7:242-10Martinez-Murillo P; Pramanik L; Sundling C; Hultenby K; Wretenberg P; Spangberg M; Hedestam GBK
- Article: JOURNAL OF IMMUNOLOGY. 2016;196(9):3729-3743Wang Y; Sundling C; Wilson R; O'Dell S; Chen Y; Dai K; Phad GE; Zhu J; Xiao Y; Mascola JR; Hedestam GBK; Wyatt RT; Li Y
- Article: SCIENTIFIC REPORTS. 2016;6:20987Dai K; Khan SN; Wang Y; He L; Guenaga J; Ingale J; Sundling C; O'Dell S; McKee K; Phad G; Corcoran M; Wilson R; Mascola JR; Zhu J; Li Y; Hedestam GBK; Wyatt RT
- Article: MBIO. 2015;6(6):e01375-e01315Dai K; He L; Khan SN; O'Dell S; McKee K; Tran K; Li Y; Sundling C; Morris CD; Mascola JR; Hedestam GBK; Wyatt RT; Zhu J
- Article: JOURNAL OF IMMUNOLOGY. 2015;194(12):5903-5914Phad GE; Bernat NV; Feng Y; Ingale J; Murillo PAM; O'Dell S; Li Y; Mascola JR; Sundling C; Wyatt RT; Hedestam GBK
- Article: SCIENTIFIC REPORTS. 2015;5:8925Martinez P; Sundling C; O'Dell S; Mascola JR; Wyatt RT; Hedestam GBK
- Article: PLOS PATHOGENS. 2014;10(8):e1004337Navis M; Karen T; Bale S; Phad GE; Guenaga J; Wilson R; Soldemo M; McKee K; Sundling C; Mascola J; Li Y; Wyatt RT; Hedestam GBK
- Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2014;408:137-141Spangberg M; Martinez P; Fredlund H; Hedestam GBK; Sundling C
- Article: JOURNAL OF IMMUNOLOGY. 2014;192(8):3637-3644Sundling C; Zhang Z; Phad GE; Sheng Z; Wang Y; Mascola JR; Li Y; Wyatt RT; Shapiro L; Hedestam GBK
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2014;111(7):E738-E747Tran K; Poulsen C; Guenaga J; de Val N; Wilson R; Sundling C; Li Y; Stanfield RL; Wilson IA; Ward AB; Hedestam GBK; Wyatt RT
- Article: JOURNAL OF INFECTIOUS DISEASES. 2013;207(3):426-431Sundling C; Martinez P; Soldemo M; Spangberg M; Bengtsson KL; Stertman L; Forsell MNE; Hedestam GBK
- Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2012;386(1-2):85-93Sundling C; Phad G; Douagi I; Navis M; Hedestam GBK
- Journal article: SCIENCE TRANSLATIONAL MEDICINE. 2012;4(142)Sundling C; Li Y; Huynh N; Poulsen C; Wilson R; O'Dell S; Feng Y; Mascola JR; Wyatt RT; Hedestam GBK
- Article: SCIENCE TRANSLATIONAL MEDICINE. 2012;4(142):142ra96Sundling C; Li Y; Huynh N; Poulsen C; Wilson R; O'Dell S; Feng Y; Mascola JR; Wyatt RT; Hedestam GBK
- Article: IMMUNOLOGY. 2011;134(3):257-269Gujer C; Sundling C; Seder RA; Hedestam GBK; Lore K
- Article: JOURNAL OF LEUKOCYTE BIOLOGY. 2011;89(6):811-821Gujer C; Sandgren KJ; Douagi I; Adams WC; Sundling C; Smed-Sorensen A; Seder RA; Hedestam GBK; Lore K
- Article: JOURNAL OF VIROLOGY. 2010;84(18):9086-9095Sundling C; O'Dell S; Douagi I; Forsell MN; Morner A; Lore K; Mascola JR; Wyatt RT; Hedestam GBK
- Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2010;207(9):2003-2017Sundling C; Forsell MNE; O'Dell S; Feng Y; Chakrabarti B; Rao SS; Lore K; Mascola JR; Wyatt RT; Douagi I; Hedestam GBK
- Article: JOURNAL OF VIROLOGY. 2010;84(4):1683-1695Douagi I; Forsell MNE; Sundling C; O'Dell S; Feng Y; Dosenovic P; Li Y; Seder R; Lore K; Mascola JR; Wyatt RT; Hedestam GBK
- Article: JOURNAL OF IMMUNOLOGY. 2009;182(4):1991-2001Douagi I; Gujer C; Sundling C; Adams WC; Smed-Soerensen A; Seder RA; Hedestam GBK; Lore K
- Article: JOURNAL OF VIROLOGY. 2009;83(2):540-551Moerner A; Douagi I; Forsell MNE; Sundling C; Dosenovic P; O'Dell S; Dey B; Kwong PD; Voss G; Thorstensson R; Mascola JR; Wyatt RT; Hedestam GBK
- Article: JOURNAL OF GENERAL VIROLOGY. 2008;89(Pt 12):2954-2964Sundling C; Schon K; Morner A; Forsell MNE; Wyatt RT; Thorstensson R; Hedestam GBK; Lycke NY
- Article: JOURNAL OF GENERAL VIROLOGY. 2007;88(Pt 10):2774-2779Forsell MNE; McInerney GM; Dosenovic P; Hidmark AS; Eriksson C; Liljestorm P; Grundner C; Hedestam GBK
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Alla övriga publikationer
- Preprint: BIORXIV. 2025Lautenbach MJ; Kleberg L; Xi P; Courey-Ghaouzi A-D; Gower MS; Sousa Silva C; Färnert A; Sundling C
- Preprint: BIORXIV. 2025Corcoran M; Narang S; Kaduk M; Chernyshev M; Färnert A; Sundling C; Hedestam GK
- Preprint: MEDRXIV. 2025Folkesson E; Foroogh F; Kjellgren V; Jakobsson M; Grunewald L; Hellberg J; Silva CS; Gower M; Kleberg L; Grönlund H; Correia-Neves M; Makower B; Källenius G; Bruchfeld J; Sundling C
- Preprint: MEDRXIV. 2025Mousavian Z; Folkesson E; Silva CS; Palmieri F; Vanini V; Cuzzi G; Correia-Neves M; Goletti D; Bruchfeld J; Källenius G; Sundling C
- Preprint: MEDRXIV. 2025Wanjiku P; Orindi B; Mwacharo J; Chemweno J; Karanja H; Kronsteiner-Dobramysl B; Kai O; Wright D; Ochola-Oyier LI; Sundling C; Dunachie S; Warimwe G; Farnert A; Bejon P; Ndungu F; Nduati E
- Preprint: BIORXIV. 2024Zerebinski J; Margerie L; Han NS; Moll M; Ritvos M; Jahnmatz P; Ahlborg N; Ngasala B; Rooth I; Sjöberg R; Sundling C; Yman V; Färnert A; Plaza D
- Conference publication: EUROPEAN JOURNAL OF IMMUNOLOGY. 2024;54:662Xi P; Sandoz P; Lautenbach MJ; Onfelt B; Farnert A; Sundling C
- Conference publication: EUROPEAN JOURNAL OF IMMUNOLOGY. 2024;54:631Kleberg L; Courey-Ghaouzi A; Lautenbach MJ; Farnert A; Sundling C
- Conference publication: EUROPEAN JOURNAL OF IMMUNOLOGY. 2024;54:97Courey-Ghaouzil A; Kleberg L; Lautenbach MJ; Malagi G; Mousavian Z; Phad G; Forsell M; Farnert A; Sundling C
- Preprint: BIORXIV. 2024Silva C; Folkesson E; Foroogh F; Gower M; Kleberg L; Xi P; Sahran D; Bruchfeld J; Correia-Neves M; Källenius G; Sundling C
- Preprint: MEDRXIV. 2024Rodriguez L; Tan Z; Lakshmikanth T; Wang J; Barcenilla H; Swank Z; Zuo F; Abolhassani H; Pavlovitch-Bedzyk AJ; Wang C; Gonzalez L; Mugabo CH; Johnsson A; Chen Y; James A; Mikes J; Kleberg L; Sundling C; Björnson M; Bonnier MN; Ståhlberg M; Runold M; Björkander S; Melén E; Meyts I; Weyenbergh JV; Hammarström Q-P; Davis M; Walt D; Landegren N; COVID Human Genetic Effort; Aiuti A; Casari G; Casanova J-L; Jamoulle M; Bruchfeld J; Brodin P
- Preprint: MEDRXIV. 2023Sundling C; Yman V; Mousavian Z; Angenendt S; Foroogh F; von Horn E; Lautenbach MJ; Grunewald J; Färnert A; Sondén K
- Preprint: BIORXIV. 2023Kleberg L; Courey-Ghaouzi A-D; Lautenbach MJ; Färnert A; Sundling C
- Review: FRONTIERS IN IMMUNOLOGY. 2022;13:1035122Correia-Neves M; Nigou J; Mousavian Z; Sundling C; Kallenius G
- Conference publication: EUROPEAN JOURNAL OF IMMUNOLOGY. 2022;52:15Mousavian Z; Folkesson E; Froberg G; Foroogh F; Correia-Neves M; Goletti D; Bruchfeld J; Kallenius G; Sundling C
- Conference publication: EUROPEAN JOURNAL OF IMMUNOLOGY. 2022;52:29Silva CS; Folkesson E; Froberg G; Chambers BJ; Lakshmikanth T; Brodin P; Bruchfeld J; Correia-Neves M; Kallenius G; Sundling C
- Conference publication: EUROPEAN JOURNAL OF IMMUNOLOGY. 2022;52:41Lautenbach MJ; Yman V; Silva SC; Kadri N; Angenendt S; Broumou I; Chan S; Wang J; Sonden K; Plaza DF; Brodin P; Farnert A; Sundling C
- Preprint: BIORXIV. 2022Corcoran M; Chernyshev M; Mandolesi M; Narang S; Kaduk M; Sundling C; Färnert A; Bernhardsson C; Larena M; Jakobsson M; Karlsson Hedestam G
- Preprint: MEDRXIV. 2022Yu M; Charles A; Cagigi A; Christ W; Österberg B; Falck-Jones S; Azizmohammadi L; Åhlberg E; Falck-Jones R; Svensson J; Nie M; Warnqvist A; Hellgren F; Lenart K; Cerveira RA; Ols S; Lindgren G; Lin A; Maecker H; Bell M; Johansson N; Albert J; Sundling C; Czarnewski P; Klingström J; Färnert A; Loré K; Smed-Sörensen A
- Review: FRONTIERS IN IMMUNOLOGY. 2022;13:908034Courey-Ghaouzi A-D; Kleberg L; Sundling C
- Preprint: BIORXIV. 2022Plaza DF; Zerebinski J; Broumou I; Lautenbach MJ; Ngasala B; Sundling C; Färnert A
- Preprint: MEDRXIV. 2022Mousavian Z; Folkesson E; Fröberg G; Foroogh F; Correia-Neves M; Bruchfeld J; Källenius G; Sundling C
- Preprint: BIORXIV. 2022Cantera JL; Lillis LM; Peck RB; Moreau E; Schouten JA; Davis P; Drain PK; Andama A; Pinter A; Kawasaki M; Källenius G; Sundling C; Dobos KM; Flores D; Chatterjee D; Murphy E; Halas OR; Boyle DS
- Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2021;94(6)Silva C; Sundling C; Folkesson E; Froberg G; Nobrega C; Canto--Gomes J; Chambers B; Lakshmikanth T; Brodin P; Bruchfeld J; Nigou J; Correia-Neves M; Kallenius G
- Preprint: BIORXIV. 2021Lautenbach MJ; Yman V; Kadri N; Plaza DF; Angenendt S; Sondén K; Färnert A; Sundling C
- Conference publication: EUROPEAN JOURNAL OF IMMUNOLOGY. 2021;51:297Silva CS; Sundling C; Folkesson E; Froberg G; Nobrega C; Chambers BJ; Lakshmikanth T; Brodin P; Bruchfeld J; Nigou J; Neves MC; Kallenius G
- Preprint: BIORXIV. 2021Silva C; Sundling C; Folkeson E; Fröberg G; Nobrega C; Canto-Gomes J; Chambers B; Lakshmikanth T; Brodin P; Bruchfeld J; Nigou J; Correia-Neves M; Källenius G
- Preprint: MEDRXIV. 2020Yman V; Tuju J; White M; Kamuyu G; Mwai K; Kibinge N; Asghar M; Sundling C; Sonden K; Murungi L; Kiboi D; Kimathi R; Chege T; Chepsat E; Kiyuka P; Nyamako L; Osier F; Farnert A
- Review: FRONTIERS IN IMMUNOLOGY. 2019;10:1968Correia-Neves M; Sundling C; Cooper A; Kallenius G
- Preprint: BIORXIV. 2019Kerkman P; Dernstedt A; Tadala L; Mittler E; Dannborg M; Sundling C; Maleki K; Tauriainen J; Tuiskunen-Bäck A; Wigren BJ; Ocaya P; Thunberg T; Jangra R; Román-Sosa G; Guardado-Calvo P; Rey F; Klingström J; Chandran K; Puhar A; Ahlm C; Forsell M
- Conference publication: AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE. 2019;101:290Yman V; Tuju J; White MT; Kamuyu G; Mwai K; Kibinge N; Asghar M; Sundling C; Sonden K; Bottai M; Murungi L; Kiboi D; Kimathi R; Chege T; Chepsat E; Kiyuka P; Nyamako L; Draper SJ; Osier FH; Farnert A
- Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):250Sundling C; Butt D; Suan D; Lau A; Brink R
- Review: CURRENT OPINION IN IMMUNOLOGY. 2017;45:97-102Suan D; Sundling C; Brink R
- Conference publication: AIDS RESEARCH AND HUMAN RETROVIRUSES. 2013;29(11):A58Phad GE; Sundling C; Zhang Z; Navis M; O'Dell S; Li Y; Wyatt R; Mascola J; Shapiro L; Hedestam GBK
- Conference publication: AIDS RESEARCH AND HUMAN RETROVIRUSES. 2013;29(11):A164Tran K; Poulsen C; Guenaga J; de Val Alda N; Sundling C; Wilson R; Li Y; Stanfield R; Wilson I; Ward AB; Karlsson GBH; Wyatt RT
- Conference publication: AIDS RESEARCH AND HUMAN RETROVIRUSES. 2013;29(11):A41-A42Navis M; Tran K; Li Y; Phad G; Sundling C; Wilson R; Soldemo M; McKee K; Mascola J; Wyatt RT; Hedestam GBK
- Conference publication: AIDS RESEARCH AND HUMAN RETROVIRUSES. 2013;29(11):A7Murillo PAM; Sundling C; Feng Y; O'Dell S; Reimann K; Mascola J; Wyatt R; Hedestam GBK
- Conference publication: AIDS RESEARCH AND HUMAN RETROVIRUSES. 2013;29(11):A170Wang Y; Sundling C; Dai K; Wilson R; O'Dell S; Zhu J; Xiao Y; Mascola JR; Hedestam GBK; Wyatt RT; Li Y
- Doctoral thesis: 2012Sundling C
- Conference publication: AIDS RESEARCH AND HUMAN RETROVIRUSES. 2011;27(10):A9-A10Sundling C; Li Y; Huynh N; Wilson R; O'Dell S; Mascola JR; Wyatt RT; Hedestam GBK
- Corrigendum: JOURNAL OF EXPERIMENTAL MEDICINE. 2010;207(10):2283Sundling C; Forsell MNE; O'Dell S; Feng Y; Chakrabarti B; Rao SS; Lore K; Mascola JR; Wyatt RT; Douagi I; Hedestam GBK
- Licentiate thesis: 2010Sundling C
- Meeting abstract: RETROVIROLOGY. 2009;6:o35Douagi I; Forsell MM; Sundling C; O'dell S; Seder R; Mascola JR; Lore K; Wyatt RT
- Meeting abstract: RETROVIROLOGY. 2009;6:p83Sundling C; Soldemo M; Chakrabarti B; Forsell MN; Lore K; Wyatt RT; Douagi I
- Conference publication: AIDS RESEARCH AND HUMAN RETROVIRUSES. 2008;24:45-46Douagi I; Forsell MN; Sundling C; O'Dell S; Dosenovic P; Li Y; Mascola JR; Lore K; Wyatt RT; Hedestam GBK
- Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2008;68(2):238Douagi I; Gujer C; Sundling C; Adams WC; Smed-Soerensen A; Seder RA; Karlsson-Hedestam G; Lore K
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Forskningsbidrag
- Immune correlates of protection and disease in tuberculosisKarolinska Institutet1 March 2025 - 28 February 2030
- Immune correlates of protection and disease in tuberculosisSvenska Sällskapet för Medicinsk Forskning1 January 2025 - 31 December 2029Tuberculosis (TB) is the infectious disease that annually claims most lives worldwide. A contributing factor is its global spread, with approximately 25% of the world's population estimated to have been infected by M. tuberculosis (Mtb), causing TB. As carriers of Mtb, individuals are at risk of developing active disease throughout their lives, although it typically occurs within two years after infection. However, the majority of those infected never develop TB, indicating that most individuals exposed develop an immune response capable of controlling the infection. Currently, little is known about how this protection operates. By investigating the immune response in individuals at various stages of Mtb infection and TB disease and in different tissues, we aim to identify biological markers and mechanisms associated with infection control and disease progression. We employ several omics-based methods for broad and in-depth characterization of the immune response. We then integrate and analyze the data bioinformatically to identify overarching biological patterns associated with patient stratification. These findings are further mechanistically investigated using frozen cells from our patient cohorts as well as through cell models. These findings can be utilized to develop novel TB diagnostics that detect the disease at an earlier stage, as well as to understand the mechanisms underlying protection, which can guide future vaccine and treatment research.
- Swedish Research Council1 January 2024 - 31 December 2026Upon repeated or chronic infection, the immune system can be trained to decrease its inflammatory response. These changes enable some pathogens, such as malaria and tuberculosis to co-exist with the host with minimal impact on the host’s health. In this project, our overall aim is to study how the immune system adapts to and controls infection without leading to symptomatic disease. We have established unique cohorts of individuals with either clinical or asymptomatic malaria and clinical or asymptomatic tuberculosis. We will investigate these cohorts at an integrated systems level, cellular level, and molecular level. Our systems immunology approach includes integrating proteomic data from plasma with transcriptomic, phenotypic, and functional peripheral blood cell data and identifying differences associated with symptomatic or asymptomatic infection. We will then assess the effect of the inflammatory response on the B cell compartment, including CD11c+ B cell differentiation and antibody production. Antibody-NK cell interplay will then be evaluated functionally at bulk and single-cell resolution. Finally, we will investigate the role of individual transcription factors and cellular proteins in B cells and monocytes responding to infection or in vitro stimulation. Collectively, these experiments will improve our understanding of tolerance at the whole immune system level, the cellular level, and the molecular level.
- Swedish Research Council1 January 2022 - 31 December 2025Malaria is a potentially severe and fatal infection in non-immune individuals. An efficacious vaccine is urgently needed. Vaccine design is challenged by strain-specific immunity and extensive diversity of many of the potential vaccine targets, as well as how protection can be maintained. The aim of this project is to improve the understanding the naturally acquired immunity to malaria to guide vaccine development, focusing on antigen diversity and maintenance of immunity. The project will explore the antigen diversity of highly polymorphic merozoite surface proteins, in relation to immune responses and their role in protection. A newly developed sequencing method will allow characterization of antigen diversity across geographical areas, and the design of a peptide microarray that will be used to investigate the breadth, magnitude and cross-reactivity of antibody responses. In addition, monoclonal antibodies will be isolated to investigate whether increasing breadth of antibody responses is a result of increased breadth of individual antibody lineages or acquisition of new antibody specificities. Maintenance of immunity and memory B cell responses will be studied using a newly developed multiplex B cell FluoroSpot method. Studies are performed in on longitudinal cohort in malaria endemic areas , as well as travellers and migrants in a non-endemic setting. The overall aim is to contribute to the development of an efficacious multicomponent vaccine against malaria.
- Swedish Research Council1 January 2022 - 31 December 2024
- Swedish Heart-Lung Foundation1 January 2021 - 31 December 2021
- Swedish Research Council1 January 2020 - 31 December 2023
- Swedish Research Council1 January 2020 - 31 December 2021
- Swedish Research Council1 January 2019 - 31 December 2021
- Swedish Heart-Lung Foundation1 January 2019 - 31 December 2020
- Swedish Research Council1 January 2014 - 31 December 2016
- Swedish Research Council1 January 2010 - 31 December 2012
Anställningar
- Senior Forskare, Medicin, Solna, Karolinska Institutet, 2022-
Examina och utbildning
- Docent, Immunologi inom det medicinska området, Karolinska Institutet, 2023
- Medicine Doktorsexamen, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 2013
- LICENTIATEXAMEN, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 2010