Catharina Larsson

Om mig
Publikationer
CV
Populärvetenskap och samverkan

Om mig

Professor i medicinsk genetik
Forskargruppsledare för medicinsk genetik inom experimentell translationell cancerforskning med laborativ verksamhet i BioClinicum.
Biträdande prefekt vid Institutionen för onkologi-patologi med uppdrag om högre lärartjänster
KI-FoUU-grupps-ordförande vid ME klinisk patologi &
cancerdiagnostik
Lärarrepresentant i Fakultetsnämnden.

Utbildning
Läkarexamen 1985
Dr Med Sci vid KI 1989
Docent vid KI 1999
Professor i medicinsk genetik vid KI 2001

Akademiska priser och utmärkelser
Eric K. Fernströms pris för yngre forskare 2005
Invald medlem i Nobelförsamlingen 2005
Göran Gustafssons pris i medicinsk forskning 2006
Invald medlem i medicinska klassen vid KVA 2008

Forskningsbeskrivning

Grundläggande och translationella studier av tumörer i endokrina organ ffa sköldkörteln och binjurarna.

Artiklar

Article: ENDOCRINE PATHOLOGY. 2024;35(4):411-418
Catching the Silent Culprits: TERT Promoter Mutation Screening of Minimally Invasive Follicular and Oncocytic Thyroid Carcinoma in Clinical Practice
Hellgren LS; Stenman A; Jatta K; Condello V; Larsson C; Zedenius J; Juhlin CC
Article: ENDOCRINE-RELATED CANCER. 2024;31(9):e230061
Genetic variants and down-regulation of CACNA1H in pheochromocytoma
Svahn F; Hose KS; Stenman A; Liu Y; Calissendorff J; Tham E; Vegvari A; Zubarev RA; Wang N; Korah R; Carling T; Zedenius J; Branstrom R; Juhlin CC; Larsson C
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2024;:dgae589
BRAF-induced EHF Expression Affects TERT in Aggressive Papillary Thyroid Cancer
Xu Y; Gao J; Wang N; Zedenius J; Nilsson I-L; Lui W-O; Xu D; Juhlin CC; Larsson C; Mu N
Article: VIRCHOWS ARCHIV. 2024;485(1):105-114
Atrophic changes in thyroid tumors are strong indicators of underlying DICER1 mutations: a bi-institutional genotype-phenotype correlation study
Condello V; Roberts JW; Stenman A; Larsson C; Viswanathan K; Juhlin CC
Article: ESMO OPEN. 2024;9(7):103617
Comprehensive genomic analysis of adrenocortical carcinoma reveals genetic profiles associated with patient survival
Sun-Zhang A; Juhlin CC; Carling T; Scholl U; Schott M; Larsson C; Bajalica-Lagercrantz S
Article: EXPERIMENTAL CELL RESEARCH. 2023;433(2):113858
Ca2+-activated K plus channels modulate membrane potential in the human parathyroid cell: Possible role in exocytosis
Branstrom R; Vukojevic V; Lu M; Shabo I; Mun H-C; Conigrave AD; Farnebo L-O; Larsson C
Article: JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY. 2023;71(8):451-458
5hmC Immunohistochemistry: A Predictor of TERT Promoter Mutational Status in Follicular Thyroid Carcinoma?
Hysek M; Hellgren SLL; Condello V; Xu Y; Larsson C; Zedenius J; Juhlin CC
Article: DIAGNOSTIC CYTOPATHOLOGY. 2023;51(6):331-340
Digital droplet PCR TERT promoter mutational screening in fine needle aspiration cytology of thyroid lesions: A highly specific technique for pre-operative identification of high-risk cases
Hysek M; Hellgren LS; Stenman A; Darai-Ramqvist E; Ljung E; Schliemann I; Condello V; Larsson C; Zedenius J; Jatta K; Juhlin CC
Article: ENDOCRINE PATHOLOGY. 2023;34(1):129-141
TOP2A Expression in Pheochromocytoma and Abdominal Paraganglioma: a Marker of Poor Clinical Outcome?
Hose KS; Stenman A; Svahn F; Larsson C; Juhlin CC
Article: SCIENTIFIC REPORTS. 2023;13(1):1070
Thyroglobulin expression, Ki-67 index, and lymph node ratio in the prognostic assessment of papillary thyroid cancer
Lindfors H; Karlsen M; Karlton E; Zedenius J; Larsson C; Ihre Lundgren C; Juhlin CC; Shabo I
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2022;61(5):140
Altered expression of the IGF2-H19 locus and mitochondrial respiratory complexes in adrenocortical carcinoma
Scicluna P; Caramuta S; Kjellin H; Xu C; Froebom R; Akhtar M; Gao J; Shi H; Kjellman M; Almgren M; Hoog A; Zedenius J; Ekstroem TJ; Braenstroem R; Lui W-O; Larsson C
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2022;107(10):2811-2821
Presentation, Management, and Outcomes of Urinary Bladder Paraganglioma: Results From a Multicenter Study
Yu K; Ebbehoj AL; Obeid H; Vaidya A; Else T; Wachtel H; Main AM; Sondergaard E; Christensen LL; Juhlin CC; Calissendorff J; Cohen DL; Bennett B; Andersen MS; Larsson C; Almeida MQ; Fishbein L; Boorjian SA; Young WFJ; Bancos I
Article: NATURE METABOLISM. 2022;4(6):739-758
Impaired oxygen-sensitive regulation of mitochondrial biogenesis within the von Hippel-Lindau syndrome
Li S; Li W; Yuan J; Bullova P; Wu J; Zhang X; Liu Y; Plescher M; Rodriguez J; Bedoya-Reina OC; Jannig PR; Valente-Silva P; Yu M; Henriksson MA; Zubarev RA; Smed-Sorensen A; Suzuki CK; Ruas JL; Holmberg J; Larsson C; Christofer Juhlin C; von Kriegsheim A; Cao Y; Schlisio S
Article: ENDOCRINE PATHOLOGY. 2022;33(2):231-242
Prognostic Utility of the Ki-67 Labeling Index in Follicular Thyroid Tumors: a 20-Year Experience from a Tertiary Thyroid Center
Hellgren LS; Stenman A; Paulsson JO; Hoog A; Larsson C; Zedenius J; Juhlin CC
Article: BIOMEDICINE & PHARMACOTHERAPY. 2022;149:112796
Synergistic effects of telomerase reverse transcriptase and regulator of telomere elongation helicase 1 on aggressiveness and outcomes in adrenocortical carcinoma
Yuan H; Wu Y; Wang J; Qin X; Huang Y; Yan L; Fana Y; Zedenius J; Juhlin CC; Larsson C; Lui W-O; Xu D
Article: BIOMEDICINES. 2022;10(5):1004
Whole-Exome Sequencing of Germline Variants in Non-BRCA Families with Hereditary Breast Cancer
Liu Y; Helgadottir HT; Kharaziha P; Choi J; Lopez-Giraldez F; Mane SM; Hoiom V; Juhlin CC; Larsson C; Bajalica-Lagercrantz S
Article: CANCERS. 2022;14(6):1385
Downregulation and Hypermethylation of GABPB1 Is Associated with Aggressive Thyroid Cancer Features
Xing X; Mu N; Yuan X; Wang N; Juhlin CC; Straat K; Larsson C; Neo SY; Xu D
Article: ISCIENCE. 2021;24(11):103264
Merkel cell polyomavirus T-antigens regulate DICER1 mRNA stability and translation through HSC70
Gao J; Shi H; Juhlin CC; Larsson C; Lui W-O
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(19):10600
Imatinib Regulates miR-483-3p and Mitochondrial Respiratory Complexes in Gastrointestinal Stromal Tumors
Huang W-K; Shi H; Akcakaya P; Zeljic K; Gangaev A; Caramuta S; Yeh C-N; Branstrom R; Larsson C; Lui W-O
Article: NATURE COMMUNICATIONS. 2021;12(1):5309
Single-nuclei transcriptomes from human adrenal gland reveal distinct cellular identities of low and high-risk neuroblastoma tumors
Bedoya-Reina OC; Li W; Arceo M; Plescher M; Bullova P; Pui H; Kaucka M; Kharchenko P; Martinsson T; Holmberg J; Adameyko I; Deng Q; Larsson C; Juhlin CC; Kogner P; Schlisio S
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(12):6345
Association between Predicted Effects of TP53 Missense Variants on Protein Conformation and Their Phenotypic Presentation as Li-Fraumeni Syndrome or Hereditary Breast Cancer
Liu Y; Axell O; van Leeuwen T; Konrat R; Kharaziha P; Larsson C; Wright APH; Bajalica-Lagercrantz S
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2021;557:14-19
Direct interaction of the ATP-sensitive K⁺ channel by the tyrosine kinase inhibitors imatinib, sunitinib and nilotinib
Frobom R; Berglund E; Aspinwall CA; Lui W-O; Nilsson I-L; Larsson C; Branstrom R
Article: JOURNAL OF CLINICAL PATHOLOGY. 2021;75(10):658-662
Nuclear-specific accumulation of telomerase reverse transcriptase (TERT) mRNA in TERT promoter mutated follicular thyroid tumours visualised by in situ hybridisation: a possible clinical screening tool?
Hellgren LS; Olsson A; Kaufeldt A; Paulsson JO; Hysek M; Stenman A; Zedenius J; Larsson C; Hoog A; Juhlin CC
Article: NUCLEIC ACIDS RESEARCH. 2021;49(5):2509-2521
Aberrant splicing in neuroblastoma generates RNA-fusion transcripts and provides vulnerability to spliceosome inhibitors
Shi Y; Yuan J; Rraklli V; Maxymovitz E; Cipullo M; Liu M; Li S; Westerlund I; Bedoya-Reina OC; Bullova P; Rorbach J; Juhlin CC; Stenman A; Larsson C; Kogner P; O'Sullivan MJ; Schlisio S; Holmberg J
Article: JOURNAL OF MOLECULAR DIAGNOSTICS. 2021;23(2):212-222
Spatial Distribution Patterns of Clinically Relevant TERT Promoter Mutations in Follicular Thyroid Tumors of Uncertain Malignant Potential Advantages of the Digital Droplet PCR Technique
Hysek M; Jatta K; Hellgren LS; Stenman A; Larsson C; Zedenius J; Juhlin CC
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2020;21(21):8072
Activation of RAS Signalling is Associated with Altered Cell Adhesion in Phaeochromocytoma
Rossitti HM; Dutta RK; Larsson C; Ghayee HK; Soderkvist P; Gimm O
Article: CANCERS. 2020;12(8):2133
PLEKHS1 Over-Expression is Associated with Metastases and Poor Outcomes in Papillary Thyroid Carcinoma
Xing X; Mu N; Yuan X; Wang N; Juhlin CC; Straat K; Larsson C; Xu D
Article: CELLS. 2020;9(6):1333
Heterogeneity of Metabolic Vulnerability in Imatinib-Resistant Gastrointestinal Stromal Tumor
Huang W-K; Gao J; Chen Z; Shi H; Yuan J; Cui HL; Yeh C-N; Branstrom R; Larsson C; Li S; Lui W-O
Article: ENDOCRINE-RELATED CANCER. 2020;27(5):295-308
GABPA-dependent down-regulation of DICER1 in follicular thyroid tumours
Paulsson JO; Wang N; Gao J; Stenman A; Zedenius J; Mu N; Lui W-O; Larsson C; Juhlin CC
Article: INTERNATIONAL JOURNAL OF CANCER. 2020;146(6):1652-1666
Merkel cell polyomavirus oncoproteins induce microRNAs that suppress multiple autophagy genes
Kumar S; Xie H; Shi H; Gao J; Juhlin CC; Bjornhagen V; Hoog A; Lee L; Larsson C; Lui W-O
Article: EPIGENETICS. 2019;14(12):1224-1233
Telomerase activation in small intestinal neuroendocrine tumours is associated with aberrant TERT promoter methylation, but not hot-spot mutations
Fotouhi O; Ghaderi M; Wang N; Zedenius J; Kjellman M; Xu D; Juhlin CC; Larsson C
Article: ONCOGENE. 2019;38(43):6881-6897
Proteomics identifies neddylation as a potential therapy target in small intestinal neuroendocrine tumors
Fotouhi O; Kjellin H; Juhlin CC; Pan Y; Vesterlund M; Ghaderi M; Yousef A; Andersson-Sand H; Kharaziha P; Caramuta S; Kjellman M; Zedenius J; Larsson C; Orre LM
Article: CANCERS. 2019;11(10):1443
Clinical Routine TERT Promoter Mutational Screening of Follicular Thyroid Tumors of Uncertain Malignant Potential (FT-UMPs): A Useful Predictor of Metastatic Disease
Hysek M; Paulsson JO; Jatta K; Shabo I; Stenman A; Hoog A; Larsson C; Zedenius J; Juhlin CC
Article: ENDOCRINE PATHOLOGY. 2019;30(3):246-248
TERT Promoter Mutation Spatial Heterogeneity in a Metastatic Follicular Thyroid Carcinoma: Implications for Clinical Work-Up
Stenman A; Hysek M; Jatta K; Branstrom R; Darai-Ramqvist E; Paulsson JO; Wang N; Larsson C; Zedenius J; Juhlin CC
Article: CLINICAL GENETICS. 2019;96(3):216-225
Functional characterization of novel germline TP53 variants in Swedish families
Kharaziha P; Ceder S; Axell O; Krall M; Fotouhi O; Bohm S; Lain S; Borg A; Larsson C; Wiman KG; Tham E; Bajalica-Lagercrantz S
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2019;116(34):16997-17006
EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance
Li S; Rodriguez J; Li W; Bullova P; Fell SM; Surova O; Westerlund I; Topcic D; Bergsland M; Stenman A; Muhr J; Nister M; Holmberg J; Juhlin CC; Larsson C; von Kriegsheim A; Kaelin WGJ; Schlisio S
Article: JAMA NETWORK OPEN. 2019;2(8):e198898
Comparison of Pheochromocytoma-Specific Morbidity and Mortality Among Adults With Bilateral Pheochromocytomas Undergoing Total Adrenalectomy vs Cortical-Sparing Adrenalectomy
Neumann HPH; Tsoy U; Bancos I; Amodru V; Walz MK; Tirosh A; Kaur RJ; McKenzie T; Qi X; Bandgar T; Petrov R; Yukina MY; Roslyakova A; van der Horst-Schrivers ANA; Berends AMA; Hoff AO; Castroneves LA; Ferrara AM; Rizzati S; Mian C; Dvorakova S; Hasse-Lazar K; Kvachenyuk A; Peczkowska M; Loli P; Erenler F; Krauss T; Almeida MQ; Liu L; Zhu F; Recasens M; Wohllk N; Corssmit EPM; Shafigullina Z; Calissendorff J; Grozinsky-Glasberg S; Kunavisarut T; Schalin-Jantti C; Castinetti F; Vlcek P; Beltsevich D; Egorov VI; Schiavi F; Links TP; Lechan RM; Bausch B; Young WFJ; Eng C; Jaiswal SK; Zschiedrich S; Fragoso MCBV; Pereira MAA; Li M; Biarnes Costa J; Juhlin CC; Gross D; Violante AHD; Kocjan T; Ngeow J; Yoel U; Fraenkel M; Simsir IY; Ugurlu MU; Ziagaki A; Robles Diaz L; Kudlai IS; Gimm O; Scherbaum CR; Abebe-Campino G; Barbon G; Taschin E; Malinoc A; Khudiakova NV; Ivanov NV; Pfeifer M; Zovato S; Ploeckinger U; Makay O; Grineva E; Jarzab B; Januszewicz A; Shah N; Seufert J; Opocher G; Larsson C
Article: ANTICANCER RESEARCH. 2019;39(7):3433-3442
Biochemical Inhibition of DOG1/TMEM16A Achieves Antitumoral Effects in Human Gastrointestinal Stromal Tumor Cells In Vitro
Frobom R; Sellberg F; Xu C; Zhao A; Larsson C; Lui W-O; Nilsson I-L; Berglund E; Branstrom R
Article: AMERICAN JOURNAL OF SURGICAL PATHOLOGY. 2019;43(3):409-421
Molecular Profiling of Pheochromocytoma and Abdominal Paraganglioma Stratified by the PASS Algorithm Reveals Chromogranin B as Associated With Histologic Prediction of Malignant Behavior
Stenman A; Svahn F; Hojjat-Farsangi M; Zedenius J; Soderkvist P; Gimm O; Larsson C; Juhlin CC
Article: ONCOGENE. 2019;38(7):965-979
GABPA inhibits invasion/metastasis in papillary thyroid carcinoma by regulating DICER1 expression
Yuan X; Mu N; Wang N; Straat K; Sofiadis A; Guo Y; Stenman A; Li K; Cheng G; Zhang L; Kong F; Ekblad L; Wennerberg J; Nilsson I-L; Juhlin CC; Larsson C; Xu D
Article: CANCERS. 2018;10(11):443
MiR-375 Regulation of LDHB Plays Distinct Roles in Polyomavirus-Positive and -Negative Merkel Cell Carcinoma
Kumar S; Xie H; Scicluna P; Lee L; Bjornhagen V; Hoog A; Larsson C; Lui W-O
Article: EXPERIMENTAL CELL RESEARCH. 2018;371(1):287-296
miR-125a-5p regulation increases phosphorylation of FAK that contributes to imatinib resistance in gastrointestinal stromal tumors
Huang W-K; Akcakaya P; Gangaev A; Lee L; Zeljic K; Hajeri P; Berglund E; Ghaderi M; Ahlen J; Branstrom R; Larsson C; Lui W-O
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2018;42(3):1675-1683
TERT promoter hypermethylation is associated with poor prognosis in adrenocortical carcinoma
Svahn F; Paulsson JO; Stenman A; Fotouhi O; Mu N; Murtha TD; Korah R; Carling T; Baeckdahl M; Wang N; Juhlin CC; Larsson C
Article: ENDOCRINE. 2018;61(2):293-302
High Ki-67 index in fine needle aspiration cytology of follicular thyroid tumors is associated with increased risk of carcinoma
Mu N; Juhlin CC; Tani E; Sofiadis A; Reihner E; Zedenius J; Larsson C; Nilsson I-L
Article: WORLD JOURNAL OF SURGERY. 2018;42(8):2512-2521
Wide Surgical Margin Improves the Outcome for Patients with Gastrointestinal Stromal Tumors (GISTs)
Ahlen J; Karlsson F; Wejde J; Nilsson I-L; Larsson C; Branstrom R
Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2018;470:84-95
Molecular profiles of oxyphilic and chief cell parathyroid adenoma
Lu M; Kjellin H; Fotouhi O; Lee L; Nilsson I-L; Haglund F; Hoog A; Lehtio J; Larsson C
Article: ENDOCRINE-RELATED CANCER. 2018;25(7):723-733
TERT aberrancies: a screening tool for malignancy in follicular thyroid tumours
Paulsson JO; Mu N; Shabo I; Wang N; Zedenius J; Larsson C; Juhlin CC
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2018;103(7):2640-2650
Comprehensive Genetic Analysis of Follicular Thyroid Carcinoma Predicts Prognosis Independent of Histology
Nicolson NG; Murtha TD; Dong W; Paulsson JO; Choi J; Barbieri AL; Brown TC; Kunstman JW; Larsson C; Prasad ML; Korah R; Lifton RP; Juhlin CC; Carling T
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2018;52(4):1189-1197
LRIG1 negatively regulates RET mutants and is downregulated in thyroid cancer
Lindquist D; Alsina FC; Herdenberg C; Larsson C; Hoeppener J; Wang N; Paratcha G; Tarjan M; Tot T; Henriksson R; Hedman H
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2018;52(1):55-66
MicroRNA expression profiles in non-epithelial ovarian tumors
Chang RK; Li X; Mu N; Hrydziuszko O; Garcia-Majano B; Larson C; Lui W-O
Article: PATHOBIOLOGY. 2018;85(4):211-219
Proteomic Profiling of Diffuse Large B-Cell Lymphomas
Kwiecinska A; Porwit A; Souchelnytskyi N; Kaufeldt A; Larsson C; Bajalica-Lagercrantz S; Souchelnytskyi S
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2017;177(6):445-453
Inflammatory infiltrates in parathyroid tumors
Haglund F; Hallstrom BM; Nilsson I-L; Hoog A; Juhlin CC; Larsson C
Article: ONCOLOGIST. 2017;22(10):1178-1188
TERT Promoter Hypermethylation in Gastrointestinal Cancer: A Potential Stool Biomarker
Liu L; Liu C; Fotouhi O; Fan Y; Wang K; Xia C; Shi B; Zhang G; Wang K; Kong F; Larsson C; Hu S; Xu D
Article: JAMA ONCOLOGY. 2017;3(9):1204-1212
Clinical Characterization of the Pheochromocytoma and Paraganglioma Susceptibility Genes SDHA, TMEM127, MAX, and SDHAF2 for Gene-Informed Prevention
Bausch B; Schiavi F; Ni Y; Welander J; Patocs A; Ngeow J; Wellner U; Malinoc A; Taschin E; Barbon G; Lanza V; Soederkvist P; Stenman A; Larsson C; Svahn F; Chen J-L; Marquard J; Fraenkel M; Walter MA; Peczkowska M; Prejbisz A; Jarzab B; Hasse-Lazar K; Petersenn S; Moeller LC; Meyer A; Reisch N; Trupka A; Brase C; Galiano M; Preuss SF; Kwok P; Lendvai N; Berisha G; Makay O; Boedeker CC; Weryha G; Racz K; Januszewicz A; Walz MK; Gimm O; Opocher G; Eng C; Neumann HPH
Article: CELL DEATH & DISEASE. 2017;8(5):e2759
Loss of miR-514a-3p regulation of PEG3 activates the NF-kappa B pathway in human testicular germ cell tumors
Ozata DM; Li X; Lee L; Liu J; Warsito D; Hajeri P; Hultman I; Fotouhi O; Marklund S; Ahrlund-Richter L; Juhlin CC; Larsson C; Lui W-O
Article: ONCOLOGY LETTERS. 2017;13(5):3586-3598
Evaluation of microRNA-205 expression as a potential triage marker for patients with low-grade squamous intraepithelial lesions
Xie H; Norman I; Hjerpe A; Vladic T; Larsson C; Lui W-O; Ostensson E; Andersson S
Article: BMC CANCER. 2017;17(1):164
A novel FOXO1-mediated dedifferentiation blocking role for DKK3 in adrenocortical carcinogenesis
Cheng JY; Brown TC; Murtha TD; Stenman A; Juhlin CC; Larsson C; Healy JM; Prasad ML; Knoefel WT; Krieg A; Scholl UI; Korah R; Carling T
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2017;50(2):356-364
miR-223-3p regulates cell growth and apoptosis via FBXW7 suggesting an oncogenic role in human testicular germ cell tumors
Liu J; Shi H; Li X; Chen G; Larsson C; Lui W-O
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2016;101(10):3616-3627
Proteomics Suggests a Role for APC-Survivin in Response to Somatostatin Analog Treatment of Neuroendocrine Tumors
Fotouhi O; Kjellin H; Larsson C; Hashemi J; Barriuso J; Juhlin CC; Lu M; Hoog A; Pastrian LG; Lamarca A; Heredia Soto V; Zedenius J; Mendiola M; Lehtio J; Kjellman M
Article: ENDOCRINE. 2016;53(2):505-511
Minimally invasive follicular thyroid carcinomas: prognostic factors
Stenson G; Nilsson I-L; Mu N; Larsson C; Lundgren CI; Juhlin CC; Hoog A; Zedenius J
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2016;174(5):583-590
Diffuse PTH expression in parathyroid tumors argues against important functional tumor subclones
Haglund F; Juhlin CC; Kiss NB; Larsson C; Nilsson I-L; Hoog A
Article: GENES CHROMOSOMES & CANCER. 2016;55(5):452-459
HRAS mutation prevalence and associated expression patterns in pheochromocytoma
Stenman A; Welander J; Gustavsson I; Brunaud L; Backdahl M; Soderkvist P; Gimm O; Juhlin CC; Larsson C
Article: ONCOTARGET. 2016;7(16):21332-21346
Genetic and epigenetic background and protein expression profiles in relation to telomerase activation in medullary thyroid carcinoma
Wang N; Kjellin H; Sofiadis A; Fotouhi O; Juhlin CC; Backdahl M; Zedenius J; Xu D; Lehtio J; Larsson C
Article: PLOS ONE. 2016;11(9):e0162379
Human Cytochrome P450 2W1 Is Not Expressed in Adrenal Cortex and Is Only Rarely Expressed in Adrenocortical Carcinomas
Nole P; Duijndam B; Stenman A; Juhlin CC; Kozyra M; Larsson C; Ingelman-Sundberg M; Johansson I
Article: EXPERIMENTAL CELL RESEARCH. 2015;336(1):158-170
Secretome protein signature of human gastrointestinal stromal tumor cells
Berglund E; Dare E; Branca RMM; Akcakaya P; Frobom R; Berggren P-O; Lui W-O; Larsson C; Zedenius J; Orre L; Lehtio J; Kim J; Branstrom R
Article: HUMAN MOLECULAR GENETICS. 2015;24(8):2318-2329
Characterization of the mutational landscape of anaplastic thyroid cancer via whole-exome sequencing
Kunstman JW; Juhlin CC; Goh G; Brown TC; Stenman A; Healy JM; Rubinstein JC; Choi M; Kiss N; Nelson-Williams C; Mane S; Rimm DL; Prasad ML; Hoog A; Zedenius J; Larsson C; Korah R; Lifton RP; Carling T
Article: ENDOCRINE CONNECTIONS. 2015;4(1):76-85
Tumour nuclear oestrogen receptor beta 1 correlates inversely with parathyroid tumour weight
Haglund F; Rosin G; Nilsson I-L; Juhlin CC; Pernow Y; Norenstedt S; Dinets A; Larsson C; Hartman J; Hoog A
Article: INTERNATIONAL JOURNAL OF CANCER. 2015;136(5):E230-E241
Novel functions and targets of miR-944 in human cervical cancer cells
Xie H; Lee L; Scicluna P; Kavak E; Larsson C; Sandberg R; Lui W-O
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2015;100(3):E493-E502
Whole-Exome Sequencing Characterizes the Landscape of Somatic Mutations and Copy Number Alterations in Adrenocortical Carcinoma
Juhlin CC; Goh G; Healy JM; Fonseca AL; Scholl UI; Stenman A; Kunstman JW; Brown TC; Overton JD; Mane SM; Nelson-Williams C; Backdahl M; Suttorp A-C; Haase M; Choi M; Schlessinger J; Rimm DL; Hoog A; Prasad ML; Korah R; Larsson C; Lifton RP; Carling T
Article: PLOS ONE. 2015;10(5):e0126472
Differential Protein Expression Profiles of Cyst Fluid from Papillary Thyroid Carcinoma and Benign Thyroid Lesions
Dinets A; Pernemalm M; Kjellin H; Sviatoha V; Sofiadis A; Juhlin CC; Zedenius J; Larsson C; Lehtio J; Hoog A
Article: BRITISH JOURNAL OF CANCER. 2014;111(11):2091-2102
microRNA expression signatures of gastrointestinal stromal tumours: associations with imatinib resistance and patient outcome
Akcakaya P; Caramuta S; Ahlen J; Ghaderi M; Berglund E; Ostman A; Branstrom R; Larsson C; Lui W-O
Article: CLINICAL CANCER RESEARCH. 2014;20(22):5733-5744
Human Anaplastic Thyroid Carcinoma Cells Are Sensitive to NK Cell-Mediated Lysis via ULBP2/5/6 and Chemoattract NK Cells
Wennerberg E; Pfefferle A; Ekblad L; Yoshimoto Y; Kremer V; Kaminskyy VO; Juhlin CC; Hoog A; Bodin I; Svjatoha V; Larsson C; Zedenius J; Wennerberg J; Lundqvist A
Article: ONCOTARGET. 2014;5(20):10048-10057
TERT promoter mutations and gene amplification: Promoting TERT expression in Merkel cell carcinoma
Xie H; Liu T; Wang N; Bjornhagen V; Hoog A; Larsson C; Lui W-O; Xu D
Article: ONCOGENE. 2014;33(42):4978-4984
The age- and shorter telomere-dependent TERT promoter mutation in follicular thyroid cell-derived carcinomas
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Article: CANCER. 2014;120(19):2965-2979
TERT Promoter Mutation as an Early Genetic Event Activating Telomerase in Follicular Thyroid Adenoma (FTA) and Atypical FTA
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Article: GENES CHROMOSOMES & CANCER. 2014;53(9):750-768
Amplification of 2p as a Genomic Marker for Transformation in Lymphoma
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Article: EXPERIMENTAL CELL RESEARCH. 2014;326(2):315-325
Functional role of the Ca²⁺-activated Cl^- channel DOG1/TMEM16A in gastrointestinal stromal tumor cells
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Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2014;99(8):E1571-E1579
Telomerase-Dependent and Independent Telomere Maintenance and its Clinical Implications in Medullary Thyroid Carcinoma
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Article: EPIGENETICS. 2014;9(7):987-997
Global hypomethylation and promoter methylation in small intestinal neuroendocrine tumors An in vivo and in vitro study
Fotouhi O; Fahmideh MA; Kjellman M; Sulaiman L; Hoog A; Zedenius J; Hashemi J; Larsson C
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2014;99(7):E1352-E1360
Rare Germline Mutations Identified by Targeted Next-Generation Sequencing of Susceptibility Genes in Pheochromocytoma and Paraganglioma
Welander J; Andreasson A; Juhlin CC; Wiseman RW; Backdahl M; Hoog A; Larsson C; Gimm O; Soderkvist P
Article: ENDOCRINE-RELATED CANCER. 2014;21(3):427-434
The activating TERT promoter mutation C228T is recurrent in subsets of adrenal tumors
Liu T; Brown TC; Juhlin CC; Andreasson A; Wang N; Backdahl M; Healy JM; Prasad ML; Korah R; Carling T; Xu D; Larsson C
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Frequent EPAS1/HIF2α exons 9 and 12 mutations in non-familial pheochromocytoma
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Intracellular concentration of the tyrosine kinase inhibitor imatinib in gastrointestinal stromal tumor cells
Berglund E; Ubhayasekera SJKA; Karlsson F; Akcakaya P; Aluthgedara W; Ahlen J; Frobom R; Nilsson I-L; Lui W-O; Larsson C; Zedenius J; Bergquist J; Branstrom R
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2014;170(4):583-591
MicroRNA expression patterns associated with hyperfunctioning and non-hyperfunctioning phenotypes in adrenocortical adenomas
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Article: WORLD JOURNAL OF SURGERY. 2014;38(3):724-732
Role of SDHAF2 and SDHD in von Hippel-Lindau Associated Pheochromocytomas
Kugelberg J; Welander J; Schiavi F; Fassina A; Backdahl M; Larsson C; Opocher G; Soderkvist P; Dahia PL; Neumann HPH; Gimm O
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2014;134(2):507-517
MicroRNA Expression Patterns Related to Merkel Cell Polyomavirus Infection in Human Merkel Cell Carcinoma
Xie H; Lee L; Caramuta S; Hoog A; Browaldh N; Bjornhagen V; Larsson C; Lui W-O
Article: PLOS ONE. 2014;9(11):e111125
Expression of the p53 Target Wig-1 Is Associated with HPV Status and Patient Survival in Cervical Carcinoma
Xu L-D; Muller S; Thoppe SR; Hellborg F; Kanter L; Lerner M; Zheng B; Lagercrantz SB; Grander D; Wallin KL; Wiman KG; Larsson C; Andersson S
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The VHL gene is epigenetically inactivated in pheochromocytomas and abdominal paragangliomas
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Copy number alterations in small intestinal neuroendocrine tumors determined by array comparative genomic hybridization
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Role of microRNAs and microRNA machinery in the pathogenesis of diffuse large B-cell lymphoma
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Clinical and functional impact of TARBP2 over-expression in adrenocortical carcinoma
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Inhibition of Parathyroid Hormone Secretion by Caffeine in Human Parathyroid Cells
Lu M; Farnebo L-O; Branstrom R; Larsson C
Article: EPIGENETICS. 2013;8(6):646-655
Global and gene-specific promoter methylation analysis in primary hyperparathyroidism
Sulaiman L; Juhlin CC; Nilsson I-L; Fotouhi O; Larsson C; Hashemi J
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Evidence for Ca²⁺-regulated ATP release in gastrointestinal stromal tumors
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Epigenetic Aspects on Therapy Development for Gastroenteropancreatic Neuroendocrine Tumors
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Anaplastic carcinoma of the thyroid gland: Treatment and outcome over 13 years at one institution
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Integrative genomics reveals frequent somatic NF1 mutations in sporadic pheochromocytomas
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Cell type and context-specific function of PLAG1 for IGF2 P3 promoter activity
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Evidence of a Functional Estrogen Receptor in Parathyroid Adenomas
Haglund F; Ma R; Huss M; Sulaiman L; Lu M; Nilsson I-L; Hoog A; Juhlin CC; Hartman J; Larsson C
Article: BMC MEDICAL GENETICS. 2012;13:83
Quantitative global and gene-specific promoter methylation in relation to biological properties of neuroblastomas
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Article: FAMILIAL CANCER. 2012;11(3):355-362
Molecular characterization of parathyroid tumors from two patients with hereditary colorectal cancer syndromes
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Genetic characterization of large parathyroid adenomas
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Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2012;166(6):1049-1060
Clinical, genetic, and immunohistochemical characterization of 70 Ukrainian adult cases with post-Chornobyl papillary thyroid carcinoma
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Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2012;166(4):657-667
Proteomic profiling of follicular and papillary thyroid tumors
Sofiadis A; Becker S; Hellman U; Hultin-Rosenberg L; Dinets A; Hulchiy M; Zedenius J; Wallin G; Foukakis T; Hoog A; Auer G; Lehtio J; Larsson C
Article: PLOS ONE. 2012;7(10):e46990
miR-205 Expression Promotes Cell Proliferation and Migration of Human Cervical Cancer Cells
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Genome-Wide and Locus Specific Alterations in CDC73/HRPT2-Mutated Parathyroid Tumors
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Prolactin Receptor in Primary Hyperparathyroidism - Expression, Functionality and Clinical Correlations
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Epigenetic Regulation of Glucose Transporter 4 by Estrogen Receptor β
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Article: ENDOCRINE-RELATED CANCER. 2011;18(6):643-655
The role of microRNA deregulation in the pathogenesis of adrenocortical carcinoma
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Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2011;411(1):208-212
Enhanced effects by 4-phenylbutyrate in combination with RTK inhibitors on proliferation in brain tumor cell models
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The pattern of gene expression and gene dose profiles of 6-Mercaptopurine- and 6-Thioguanine-resistant human leukemia cells
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Absence of nucleolar parafibromin immunoreactivity in subsets of parathyroid malignant tumours
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Molecular Characterization of Acquired Tolerance of Tumor Cells to Picropodophyllin (PPP)
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Calmodulin and calmodulin-dependent protein kinase II inhibit hormone secretion in human parathyroid adenoma
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Proteomic Study of Thyroid Tumors Reveals Frequent Up-Regulation of the Ca²⁺-Binding Protein S100A6 in Papillary Thyroid Carcinoma
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Suppression of RIZ in biologically unfavourable neuroblastomas
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Parafibromin and APC as Screening Markers for Malignant Potential in Atypical Parathyroid Adenomas
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Article: ENDOCRINE-RELATED CANCER. 2010;17(3):561-579
Recurrent genomic alterations in benign and malignant pheochromocytomas and paragangliomas revealed by whole-genome array comparative genomic hybridization analysis
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MicroRNA Expression Profiles Associated with Mutational Status and Survival in Malignant Melanoma
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Expression and association of TRPC subtypes with Orai1 and STIM1 in human parathyroid
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Frequent Promoter Hypermethylation of the APC and RASSF1A Tumour Suppressors in Parathyroid Tumours
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Detection of Genomic Amplification of the Human Telomerase Gene TERC, a Potential Marker for Triage of Women with HPV-Positive, Abnormal Pap Smears
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Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2009;85(5):617-627
Autosomal-Dominant Retinitis Pigmentosa Caused by a Mutation in SNRNP200, a Gene Required for Unwinding of U4/U6 snRNAs
Zhao C; Bellur DL; Lu S; Zhao F; Grassi MA; Bowne SJ; Sullivan LS; Daiger SP; Chen LJ; Pang CP; Zhao K; Staley JP; Larsson C
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2009;161(1):141-152
Transcriptional profiling enables molecular classification of adrenocortical tumours
Laurell C; Velazquez-Fernandez D; Lindsten K; Juhlin C; Enberg U; Geli J; Hoog A; Kjellman M; Lundeberg J; Hamberger B; Larsson C; Nilsson P; Backdahl M
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Diagnostic and prognostic potential of MIB-1 proliferation index in thyroid fine needle aspiration biopsy
Sofiadis A; Tani E; Foukakis T; Kjellman P; Skoog L; Hoog A; Wallin G; Zedenius J; Larsson C
Article: JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION. 2009;32(6):512-518
Mutation analysis of MEN1, HRPT2, CASR, CDKN1B, and AIP genes in primary hyperparathyroidism patients with features of genetic predisposition
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Gene expression profiling of leukemia T-cells resistant to methotrexate and 7-hydroxymethotrexate reveals alterations that preserve intracellular levels of folate and nucleotide biosynthesis
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Ror1, a cell surface receptor tyrosine kinase is expressed in chronic lymphocytic leukemia and may serve as a putative target for therapy
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CREB3L2-PPARγ fusion mutation identifies a thyroid signaling pathway regulated by intramembrane proteolysis
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Array-CGH identifies cyclin D1 and UBCH10 amplicons in anaplastic thyroid carcinoma
Lee J-J; Au AYM; Foukakis T; Barbaro M; Kiss N; Clifton-Bligh R; Staaf J; Borg A; Delbridge L; Robinson BG; Wallin G; Hoog A; Larsson C
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Assessment of NORE1A as a putative tumor suppressor in human neuroblastoma
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Heterogeneous expression of SNARE proteins SNAP-23, SNAP-25, syntaxin1 and VAMP in human parathyroid tissue
Lu M; Forsberg L; Hoog A; Juhlin CC; Vukojevic V; Larsson C; Conigrave AD; Delbridge LW; Gill A; Bark C; Farnebo L-O; Branstrom R
Article: ENDOCRINE-RELATED CANCER. 2008;15(2):609-621
Methylation of the p16^INK4A promoter is associated with malignant behavior in abdominal extra-adrenal paragangliomas but not pheochromocytomas
Kiss NB; Geli J; Lundberg F; Avci C; Velazquez-Fernandez D; Hashemi J; Weber G; Hoog A; Ekstrom TJ; Backdahl M; Larsson C
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Global and regional CpG methylation in pheochromocytomas and abdominal paragangliomas:: Association to malignant behavior
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Article: JOURNAL OF PATHOLOGY. 2008;215(1):87-96
Frizzled-1 is down-regulated in follicular thyroid tumours and modulates growth and invasiveness
Ulivieri A; Lavra L; Dominici R; Giacomelli L; Brunetti E; Sciacca L; Trovato M; Barresi G; Foukakis T; Jia-Jing L; Larsson C; Bartolazzi A; Sciacchitano S
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Familial non-syndromic cleft lip and palate -: analysis of the IRF6 gene and clinical phenotypes
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Article: ARCHIVES OF OPHTHALMOLOGY. 2008;126(3):388-394
Novel and recurrent KIF21A mutations in congenital fibrosis of the extraocular muscles type 1 and 3
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Characterization of 6q deletions in mature B cell lymphomas and childhood acute lymphoblastic leukemia
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Detailed assessment of copy number alterations revealing homozygous deletions in 1p and 13q in mantle cell lymphoma
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Article: MOLECULAR VISION. 2007;13(124-26):1154-1160
Two Chinese families with pulverulent congenital cataracts and ΔG91 CRYBA1 mutations
Lu S; Zhao C; Jiao H; Kere J; Tang X; Zhao F; Zhang X; Zhao K; Larsson C
Article: ENDOCRINE-RELATED CANCER. 2007;14(2):501-512
Parafibromin immunoreactivity:: its use as an additional diagnostic marker for parathyroid tumor classification
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Article: ENDOCRINE-RELATED CANCER. 2007;14(2):381-391
A PCR-based expression signature of malignancy in follicular thyroid tumors
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Molecular cytogenetic profiles of novel and established human anaplastic thyroid carcinoma models
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Article: ENDOCRINE-RELATED CANCER. 2007;14(1):125-134
The Ras effectors NORE1A and RASSF1A are frequently inactivated in pheochromocytoma and abdominal paraganglioma
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Genomic imbalances during transformation from follicular lymphoma to diffuse large B-cell lymphoma
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Pre-fractionation of archival frozen turnours for proteomics applications
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Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2006;29(5):1173-1182
A dog pedigree with familial medullary thyroid cancer
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Article: BRITISH JOURNAL OF CANCER. 2006;95(3):331-338
Frequent gain of the human telomerase gene TERC at 3q26 in cervical adenocarcinomas
Andersson S; Wallin K-L; Hellstroem A-C; Morrison LE; Hjerpe A; Auer G; Ried T; Larsson C; Heselmeyer-Haddad K
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LUMA (LUminometric Methylation Assay) -: A high throughput method to the analysis of genomic DNA methylation
Karimi M; Johansson S; Stach D; Corcoran M; Grander D; Schalling M; Bakalkin G; Lyko F; Larsson C; Ekstrom TJ
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A novel locus (RP33) for autosomal dominant retinitis pigmentosa mapping to chromosomal region 2cen-q12.1
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Article: LANCET ONCOLOGY. 2006;7(7):605-607
A 10-year-old girl with bifocal synovial sarcoma
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Loss of parafibromin expression in a subset of parathyroid adenomas
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The insulin-like growth factor-1 receptor inhibitor PPP produces only very limitedresistance in tumor cells exposed to long-term selection
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Predictors of outcome in patients with papillary thyroid carcinoma
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Detailed assessment of chromosome 22 aberrations in sporadic pheochromocytoma using array-CGH
Jarbo C; Buckley PG; Piotrowski A; Mantripragada KK; Benetkiewicz M; de Ståhl TD; Langford CF; Gregory SG; Dralle H; Gimm O; Bäckdahl M; Geli J; Larsson C; Westin G; Aring; kerström G; Dumanski JP
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2006;91(3):1143-1149
The Ras effector NORE1A is suppressed in follicular thyroid carcinomas with a PAX8-PPARγ fusion
Foukakis T; Au AYM; Wallin G; Geli J; Forsberg L; Clifton-Bligh R; Robinson BG; Lui WO; Zedenius J; Larsson C
Article: INTERNATIONAL JOURNAL OF RADIATION BIOLOGY. 2006;82(2):87-96
Evaluation of spectral karyotyping (SKY) in biodosimetry for the triage situation following gamma irradiation
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Article: PROSTATE. 2006;66(2):157-172
Cytogenetic and expression profiles associated with transformation to androgen-resistant prostate cancer
Pang ST; Weng WH; Flores-Morales A; Johansson B; Pourian MR; Nilsson P; Pousette Å; Larsson C; Norstedt G
Article: ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY. 2006;101(2):214-220
Dental findings in a family with hyperparathyroidism-jaw tumor syndrome and a novel HRPT2 gene mutation
Aldred MJ; Talacko AA; Savarirayan R; Murdolo V; Mills AE; Radden BG; Alimov A; Villablanca A; Larsson C
Article: TUMOR BIOLOGY. 2006;27(4):211-220
Molecular markers for discrimination of benign and malignant follicular thyroid tumors
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Article: INTERNAL MEDICINE. 2006;45(2):81-86
Multiple endocrine neoplasia type I and Cushing's syndrome due to an aggressive ACTH producing thymic carcinoid
Takagi J; Otake K; Morishita M; Kato H; Nakao N; Yoshikawa K; Ikeda H; Hirooka Y; Hattori Y; Larsson C; Nogimori T
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2005;13(12):1261-1267
Novel and de novo mutations of the IRF6 gene detected in patients with Van der Woude or popliteal pterygium syndrome
Peyrard-Janvid M; Pegelow M; Koillinen H; Larsson C; Fransson I; Rautio J; Hukki J; Larson O; Karsten ALA; Kere J
Article: EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES. 2005;113(9):516-521
Lack of mutations in the TSHr and Gsα genes in TSHr antibody negative Graves' disease
Elgadi A; Frisk T; Larsson C; Wallin G; Höög A; Zedenius J; Norgren S
Article: CLINICAL CANCER RESEARCH. 2005;11(17):6198-6204
Prognostic impact of immunohistochemical expression of ezrin in highly malignant soft tissue sarcomas
Weng WH; Åhlén J; Åström K; Lui WO; Larsson C
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2005;13(8):970-977
Loss of ZDHHC15 expression in a woman with a balanced translocation t(X;15)(q13.3;cen) and severe mental retardation
Mansouri MR; Marklund L; Gustavsson P; Davey E; Carlsson B; Larsson C; White I; Gustavson KH; Dahl N
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2005;26(5):1385-1391
Deletions and altered expression of the RIZ1 tumour suppressor gene in 1p36 in pheochromocytomas and abdominal paragangliomas
Geli J; Nord B; Frisk T; Elder EE; Ekström TJ; Carling T; Bäckdahl M; Larsson C
Article: JOURNAL OF SURGICAL ONCOLOGY. 2005;89(3):193-201
Pheochromocytoma and functional paraganglioma syndrome: No longer the 10% tumor
Elder EE; Elder G; Larsson C
Article: ANTICANCER RESEARCH. 2005;25(2A):683-691
Immunophenotypic and molecular cytogenetic features of the cell line UP-LN1 established from a lymph node metastasis of a poorly-differentiated carcinoma
Chang CTR; Weng WH; Chou ASB; Chuang CK; Porwit-Mcdonald A; Pang ST; Larsson C; Liao SK
Article: MODERN PATHOLOGY. 2005;18(3):331-339
Mantle cell lymphomas with clonal immunoglobulin V_H3-21 gene rearrangements exhibit fewer genomic imbalances than mantle cell lymphomas utilizing other immunoglobulin V_H genes
Thelander EF; Walsh SH; Thorsélius M; Laurell A; Landgren O; Larsson C; Rosenquist R; Lagercrantz S
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2005;152(3):459-470
Distinction in gene expression profiles demonstrated in parathyroid adenomas by high-density oligoarray technology
Forsberg L; Björck E; Hashemi J; Zedenius J; Höög A; Farnebo LO; Reimers M; Larsson C
Article: ONCOGENE. 2005;24(8):1467-1476
Expression profiling reveals a distinct transcription signature in follicular thyroid carcinomas with a PAX8-PPARγ fusion oncogene
Lui WO; Foukakis T; Lidén J; Thoppe SR; Dwight T; Höög A; Zedenius J; Wallin G; Reimers M; Larsson C
Article: CLINICAL CANCER RESEARCH. 2005;11(1):206-216
Insulin-like growth factor type 1 receptor expression correlates to good prognosis in highly malignant soft tissue sarcoma
Åhlén J; Wejde J; Brosjö O; von Rosen A; Weng WH; Girnita L; Larsson O; Larsson C
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2005;26(1):141-149
Molecular cytogenetic characterization of primary cultures and established cell lines from non-medullary thyroid tumors
Foukakis T; Thoppe SR; Lagercrantz S; Dwight T; Weng WH; Svensson A; Höög A; Zedenius J; Wallin G; Lui WO; Larsson C
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2005;26(1):5-16
Loss of chromosome 13q is a frequently acquired event in genetic progression of soft tissue sarcomas in the abdominal cavity
Weng WH; Lerner M; Grander D; Åhlén J; Villablanca A; Pang ST; Wejde J; Lui WO; Larsson C
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2004;25(4):955-960
Molecular cytogenetic characterization shows higher genetic homogeneity in conventional renal cell carcinoma compared to other kidney cancers
Alimov A; Sundelin B; Bergerheim U; Pavlenko M; Pisa P; Zetterberg A; Larsson C; Lagercrantz S
Article: GENES CHROMOSOMES & CANCER. 2004;41(2):133-144
Spontaneously immortalized human T lymphocytes develop gain of chromosomal region 2p13-24 as an early and common genetic event
Siwicki JK; Berglund M; Rygier J; Pienkowska-Grela B; Grygalewicz B; Degerman S; Golovleva I; Chrzanowska KH; Lagercrantz S; Blennow E; Roos G; Larsson C
Article: GENES CHROMOSOMES & CANCER. 2004;40(4):285-297
DLEU2 encodes an antisense RNA for the putative bicistronic RFP2/LEU5 gene in humans and mouse
Corcoran MM; Hammarsund M; Zhu CY; Lerner M; Kapanadze B; Wilson B; Larsson C; Forsberg L; Ibbotson RE; Stefan E; Oscier DG; Grandér D; Sangfelt O
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2004;25(1):179-185
Loss of 14q31-q32.2 in renal cell carcinoma is associated with high malignancy grade and poor survival
Alimov A; Sundelin B; Wang NN; Larsson C; Bergerheim U
Article: CANCER GENETICS. 2004;150(1):27-32
Characterization of large chromosome markers in a malignant fibrous histiocytoma by spectral karyotyping, comparative genomic hybridization (CGH), and array CGH
Weng WH; Wejde J; Åhlén J; Pang ST; Lui WO; Larsson C
Article: JOURNAL OF MEDICAL GENETICS. 2004;41(3):e32-32
Germline and de novo mutations in the HRPT2 tumour suppressor gene in familial isolated hyperparathyroidism (FIHP) -: art. no. e32
Villablanca A; Calender A; Forsberg L; Höög A; Cheng JD; Petillo D; Bauters C; Kahnoski K; Ebeling T; Salmela P; Richardson AL; Delbridge L; Meyrier A; Proye C; Carpten JD; Teh BT; Robinson BG; Larsson C
Article: CYTOGENETIC AND GENOME RESEARCH. 2004;106(1):28-32
Analysis of the cytogenetic stability of the human embryonal kidney cell line 293 by cytogenetic and STR profiling approaches
Bylund L; Kytölä S; Lui WO; Larsson C; Weber G
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2003;278(50):49685-49690
High extracellular Ca²⁺ hyperpolarizes human parathyroid cells via Ca²⁺-activated K⁺ channels
Välimäki S; Höög A; Larsson C; Farnebo LO; Bränström R
Article: CANCER CELL. 2003;4(5):405-413
The t(1;3) breakpoint-spanning involved in clear cell renal cell genes LSAMP and NORE1 are carcinomas
Chen JD; Lui WO; Vos MD; Clark GJ; Takahashi M; Schoumans J; Khoo SK; Petillo D; Lavery T; Sugimura J; Astuti D; Zhang C; Kagawa S; Maher ER; Larsson C; Alberts AS; Kanayama HO; Teh BT
Article: NEW ENGLAND JOURNAL OF MEDICINE. 2003;349(18):1722-1729
Somatic and germ-line mutations of the HRPT2 gene in sporadic parathyroid carcinoma
Shattuck TM; Välimäki S; Obara T; Gaz RD; Clark OH; Shoback D; Wierman ME; Tojo K; Robbins CM; Carpten JD; Farnebo LO; Larsson C; Arnold A
Article: ONCOLOGY REPORTS. 2003;10(5):1641-1645
Evaluation of immunohistochemical parameters as prognostic markers in malignant fibrous histiocytoma
Åhlén J; Weng WWH; Brosjö O; Von Rosen A; Larsson O; Larsson C
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2003;88(9):4440-4445
Involvement of the PAX8/peroxisome proliferator-activated receptor γ rearrangement in follicular thyroid tumors
Dwight T; Thoppe SR; Foukakis T; Lui WO; Wallin G; Höög A; Frisk T; Larsson C; Zedenius J
Article: BRITISH JOURNAL OF CANCER. 2003;89(4):720-726
Gain of 17q in malignant fibrous histiocytoma is associated with a longer disease-free survival and a low risk of developing distant metastasis
Weng WH; Åhlén J; Lui WO; Brosjö O; Pang ST; von Rosen A; Auer G; Larsson O; Larsson C
Article: CLINICAL ENDOCRINOLOGY. 2003;59(1):129-135
Multiple endocrine neoplasia type 1 (MEN1): genetic and clinical analysis in the Southern Chinese
Tso AWK; Rong R; Lo CY; Tan KCB; Tiu SC; Wat NMS; Xu JY; Villablanca A; Larsson C; Teh BT; Lam KSL
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2003;22(5):1003-1007
Mutation analysis of the BRG1 gene in prostate cancer clinical samples
Valdman A; Nordenskjöld A; Fang XL; Naito A; Al-Shukri S; Larsson C; Ekman P; Li CD
Article: ONCOGENE. 2003;22(14):2215-2222
Characteristic sequence motifs located at the genomic breakpoints of the translocation t(X;18) in synovial sarcomas
Wei YK; Sun MH; Nilsson G; Dwight T; Xie YT; Wang J; Hou YY; Larsson O; Larsson C; Zhu XZ
Article: THYROID. 2003;13(4):371-380
MIB-1 index in thyroid tumors:: A predictor of the clinical course in papillary thyroid carcinoma?
Kjellman P; Wallin G; Höög A; Auer G; Larsson C; Zedenius J
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2003;11(4):529-533
Difference between Swedish and Japanese men in the association between AR CAG repeats and prostate cancer suggesting a susceptibility-modifying locus overlapping the androgen receptor gene
Li CD; Grönberg H; Matsuyama H; Weber G; Nordenskjöld M; Naito K; Bergh A; Bergerheim U; Damber JE; Larsson C; Ekman P
Article: MODERN PATHOLOGY. 2003;16(3):246-255
Ki-67 and hTERT expression can aid in the distinction between malignant and benign pheochromocytoma and paraganglioma
Elder EE; Xu D; Höög A; Enberg U; Pisa P; Gruber A; Larsson C; Bäckdahl M
Article: CANCER GENETICS. 2003;141(1):43-48
Molecular cytogenetic characterization of four commonly used cell lines derived from Hodgkin lymphoma
Berglund M; Flordal E; Gullander J; Lui WO; Larsson C; Lagercrantz S; Enblad G
Article: NATURE GENETICS. 2002;32(4):676-680
HRPT2, encoding parafibromin, is mutated in hyperparathyroidism-jaw tumor syndrome
Carpten JD; Robbins CM; Villablanca A; Forsberg L; Presciuttini S; Bailey-Wilson J; Simonds WF; Gillanders EM; Kennedy AM; Chen JD; Agarwal SK; Sood R; Jones MP; Moses TY; Haven C; Petillo D; Leotlela PD; Harding B; Cameron D; Pannett AA; Höög A; Heath H; James-Newton LA; Robinson B; Zarbo RJ; Cavaco BM; Wassif W; Perrier ND; Rosen IB; Kristoffersson U; Turnpenny PD; Farnebo LO; Besser GM; Jackson CE; Morreau H; Trent JM; Thakker RV; Marx SJ; Teh BT; Larsson C; Hobbs MR
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2002;21(6):1197-1204
Identifying cancer-related genes in nasopharyngeal carcinoma cell lines using DNA and mRNA expression profiling analyses
Guo X; Lui WO; Qian CN; Chen JD; Gray SG; Rhodes D; Haab B; Stanbridge E; Wang HM; Hong MH; Min HQ; Larsson C; Teh BT
Article: CANCER GENETICS. 2002;139(1):38-43
Clonal development of a blastoid mantle cell lymphoma studied with comparative genomic hybridization
Flordal E; Berglund M; Rosenquist R; Erlanson M; Enblad G; Roos G; Larsson C; Lagercrantz S
Article: AMERICAN JOURNAL OF PATHOLOGY. 2002;161(4):1299-1306
Independent genetic events associated with the development of multiple parathyroid tumors in patients with primary hyperparathyroidism
Dwight T; Nelson AE; Theodosopoulos G; Richardson AL; Learoyd DL; Philips J; Delbridge L; Zedenius J; Teh BT; Larsson C; Marsh DJ; Robinson BG
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2002;21(4):727-735
Distinct target regions for chromosome 1p deletions in parathyroid adenomas and carcinomas
Välimäki S; Forsberg L; Farnebo LO; Larsson C
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2002;147(3):313-322
Involvement of the MEN1 gene locus in familial isolated hyperparathyroidism
Villablanca A; Wassif WS; Smith T; Höög A; Vierimaa O; Kassem M; Dwight T; Forsberg L; Du Q; Learoyd D; Jones K; Stranks S; Juhlin C; Teh BT; Carling T; Robinson B; Larsson C
Article: GENES CHROMOSOMES & CANCER. 2002;35(1):74-80
Silencing of the PTEN tumor-suppressor gene in anaplastic thyroid cancer
Frisk T; Foukakis T; Dwight T; Lundberg J; Höög A; Wallin G; Eng C; Zedenius J; Larsson C
Article: MODERN PATHOLOGY. 2002;15(8):807-816
Chromosomal imbalances in diffuse large B-cell lymphoma detected by comparative genomic hybridization
Berglund M; Enblad G; Flordal E; Lui WO; Backlin C; Thunberg U; Sundström C; Roos G; Allander SV; Erlanson M; Rosenquist R; Larsson C; Lagercrantz S
Article: GENES CHROMOSOMES & CANCER. 2002;34(3):325-332
Alterations of the SDHD gene locus in midgut carcinoids, Merkel cell carcinomas, pheochromocytomas, and abdominal paragangliomas
Kytölä S; Nord B; Elder EE; Carling T; Kjellman M; Cedermark B; Juhlin C; Höög A; Isola J; Larsson C
Article: ONCOGENE. 2002;21(26):4181-4190
Co-existence of SYT-SSX1 and SYT-SSX2 fusions in synovial sarcomas
Yang K; Lui WO; Xie YT; Zhang AJ; Skytting B; Mandahl N; Larsson C; Larsson O
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2002;20(6):1161-1165
Aberrations of centrosomes in adrenocortical tumors
Roshani L; Fujioka K; Auer G; Kjellman M; Lagercrantz S; Larsson C
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2002;146(5):619-627
Genetic analysis of lithium-associated parathyroid tumors
Dwight T; Kytölä S; Teh BT; Theodosopoulos G; Richardson AL; Philips J; Twigg S; Delbridge L; Marsh DJ; Nelson AE; Larsson C; Robinson BG
Article: BMC CANCER. 2002;2:5
Chromosomal aberrations in benign and malignant Bilharzia-associated bladder lesions analyzed by comparative genomic hybridization
Fadl-Elmula I; Kytola S; El Leithy M; Abdel-Hameed M; Mandahl N; Elagib A; Ibrahim M; Larsson C; Heim S
Article: ONCOGENE. 2002;21(7):1117-1122
Selective loss of chromosome 11 in pheochromocytomas associated with the VHL syndrome
Lui WO; Chen JD; Gläsker S; Bender BU; Madura C; Khoo SK; Kort E; Larsson C; Neumann HPH; Teh BT
Article: CLINICAL ENDOCRINOLOGY. 2002;56(2):261-269
Genetic and clinical characterization of sporadic cystic parathyroid tumours.
Villablanca A; Farnebo F; Teh BT; Farnebo L-O; Höög A; Larsson C
Article: MAMMALIAN GENOME. 2002;13(1):20-23
Characterization of a putative murine mitochondrial transporter homology of hMRS3/4
Li FY; Leibiger B; Leibiger I; Larsson C
Article: CLINICAL ENDOCRINOLOGY. 2002;56(2):259-267
Genetic and clinical characterization of sporadic cystic parathyroid tumours
Villablanca A; Farnebo F; Teh BT; Farnebo LO; Höög A; Larsson C
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2001;8(6):681-689
Differential expression of multiple alternative spliceforms of the Men1 tumor suppressor gene in mouse
Forsberg L; Zablewska B; Piehl F; Weber G; Lagercrantz S; Gaudray P; Höög C; Larsson C
Article: KIDNEY INTERNATIONAL. 2001;60(5):1666-1675
Heterogeneous expression of receptor mRNAs in parathyroid glands of secondary hyperparathyroidism
Välimäki S; Farnebo F; Forsberg L; Larsson C; Farnebo LO
Article: EXPERIMENTAL CELL RESEARCH. 2001;270(1):88-95
Methylation changes in the human IGF2 P3 promoter parallel IGF2 expression in the primary tumor, established cell line, and xenograft of a human hepatoblastoma
Eriksson T; Frisk T; Gray SG; von Schweinitz D; Pietsch T; Larsson C; Sandstedt B; Ekström TJ
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2001;9(10):747-752
Mapping of the second locus for the Van der Woude syndrome to chromosome 1p34
Koillinen H; Wong FK; Rautio J; Ollikainen V; Karsten A; Larson O; Teh BT; Huggare J; Lahermo P; Larsson C; Kere J
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2001;145(4):415-420
Homozygous inactivation of the MEN1 gene as a specific somatic event in a case of secondary hyperparathyroidism
Forsberg L; Villablanca A; Välimäki S; Farnebo F; Farnebo LO; Lagercrantz S; Larsson C
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2001;19(3):451-457
High level amplification of 1p32-33 and 2p22-24 in small cell lung carcinomas
Lui WO; Tanenbaum DM; Larsson C
Article: GENES CHROMOSOMES & CANCER. 2001;32(1):43-49
Gain of 1q and loss of 9q21.3-q32 are associated with a less favorable prognosis in papillary thyroid carcinoma
Kjellman P; Lagercrantz S; Höög A; Wallin G; Larsson C; Zedenius J
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2001;286(2):426-431
Menin interacts directly with the homeobox-containing protein Pem
Lemmens IH; Forsberg L; Pannett AAJ; Meyen E; Piehl F; Turner JJO; Van de Ven WJM; Thakker RV; Larsson C; Kas K
Article: WORLD JOURNAL OF SURGERY. 2001;25(7):948-956
Genetic background of adrenocortical tumor development
Kjellman M; Larsson C; Bäckdahl M
Article: NATURE GENETICS. 2001;28(3):223-231
Human mitochondrial DNA deletions associated with mutations in the gene encoding Twinkle, a phage T7 gene LF-like protein localized in mitochondria
Spelbrink JN; Li FY; Tiranti V; Nikali K; Yuan QP; Tariq M; Wanrooij S; Garrido N; Comi G; Morandi L; Santoro L; Toscano A; Fabrizi GM; Somer H; Croxen R; Beeson D; Poulton L; Suomalainen A; Jacobs HT; Zeviani M; Larsson C
Article: INTERNATIONAL JOURNAL OF CANCER. 2001;92(6):824-831
Characterization of chromosomal abnormalities in uroepithelial carcinomas by G-banding, spectral karyotyping and fish analysis
Fadl-Elmula I; Kytölä S; Pan Y; Lui WO; Derienzo G; Forsberg L; Mandahl N; Gorunova L; Bergerheim USR; Heim S; Larsson C
Article: CANCER GENETICS. 2001;127(2):128-133
A highly aggressive primitive mesenchymal tumor with a translocation (1;19)(q12;q13.2)
Lui WO; Wejde J; Tani E; Brosjö O; Kytölä S; Larsson C
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2001;18(6):1219-1225
CGH alterations in medullary thyroid carcinomas in relation to the RET M918T mutation and clinical outcome
Frisk T; Zedenius J; Lundberg J; Wallin G; Kytölä S; Larsson C
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2001;66(5):297-304
Identification of numerical and structural chromosome aberrations in 15 high hyperdiploid childhood acute lymphoblastic leukemias using spectral karyotyping
Nordgren A; Farnebo F; Johansson B; Holmgren G; Forestier E; Larsson C; Söderhäll S; Nordenskjöld M; Blennow E
Article: AMERICAN JOURNAL OF PATHOLOGY. 2001;158(5):1803-1808
Comparative genomic hybridization identifies loss of 18q22-qter as an early and specific event in tumorigenesis of midgut carcinoids
Kytölä S; Höög A; Nord B; Cedermark B; Frisk T; Larsson C; Kjellman M
Article: FEBS LETTERS. 2001;494(1-2):79-84
Characterization of a novel human putative mitochondrial transporter homologous to the yeast mitochondrial RNA splicing proteins 3 and 4
Li FY; Nikali K; Gregan J; Leibiger I; Leibiger B; Schweyen R; Larsson C; Suomalainen A
Article: CANCER GENETICS. 2001;126(1):1-7
Aberrations of chromosome 8 in 16 breast cancer cell lines by comparative genomic hybridization, fluorescence in situ hybridization, and spectral karyotyping
Rummukainen J; Kytölä S; Karhu R; Farnebo F; Larsson C; Isola JJ
Article: JOURNAL OF MEDICAL GENETICS. 2001;38(3):165-170
Association of a novel constitutional translocation t(1q;3q) with familial renal cell carcinoma
Kanayama H; Lui WO; Takahashi M; Naroda T; Kedra D; Wong FI; Kuroki Y; Nakahori Y; Larsson C; Kagawa S; Teh BT
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2001;7(3):289-294
Dominantly inherited familial myasthenia gravis as a separate genetic entity without involvement of defined candidate gene loci
Li FY; Szobor A; Croxen R; Anselmo V; Yuan QP; Lindblad K; Schalling M; Komoly S; Beeson D; Larsson C
Article: GENES CHROMOSOMES & CANCER. 2001;30(2):187-195
5q11, 8p11, and 10q22 are recurrent chromosomal breakpoints in prostate cancer cell lines
Pan Y; Lui WO; Nupponen N; Larsson C; Isola J; Visakorpi T; Bergerheim USR; Kytölä S
Article: GENE. 2001;262(1-2):51-59
Characterisation of the human APC1, the largest subunit of the anaphase-promoting complex
Jörgensen PM; Gräslund S; Betz R; Ståhl S; Larsson C; Höög C
Article: SARCOMA. 2001;5(3):143-149
Malignant Fibrous Histiocytoma, Aggressive Fibromatosis and Benign Fibrous Tumors Express mRNA for the Metalloproteinase Inducer EMMPRIN and the Metalloproteinases MMP-2 and MT1-MMP.
Ahlén J; Enberg U; Larsson C; Larsson O; Frisk T; Brosjö O; Rosen A; Bäckdahl M
Article: CYTOGENETIC AND GENOME RESEARCH. 2001;92(1-2):89-96
Chromosomal distribution, localization and expression of the human endogenous retrovirus ERV9
Svensson AC; Raudsepp T; Larsson C; Di Cristofano A; Chowdhary B; La Mantia G; Rask L; Andersson G
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2000;6(4):469-474
Expression analysis of RET and the GDNF/GFRa-1 and NTN/GFRa-2 ligand complexes in pheochromocytomas and paragangliomas
Edström E; Frisk T; Farnebo F; Höög A; Bäckdahl M; Larsson C
Article: BRITISH JOURNAL OF CANCER. 2000;83(8):1020-1025
Comparative genomic hybridization reveals population-based genetic alterations in hepatoblastomas
Gray SG; Kytölä S; Matsunaga T; Larsson C; Ekström TJ
Article: NATURE BIOTECHNOLOGY. 2000;18(9):1001-1005
Loss-of-heterozygosity analysis of small-cell lung carcinomas using single-nucleotide polymorphism arrays
Lindblad-Toh K; Tanenbaum DM; Daly MJ; Winchester E; Lui WO; Villapakkam A; Stanton SE; Larsson C; Hudson TJ; Johnson BE; Lander ES; Meyerson M
Article: INTERNATIONAL JOURNAL OF CANCER. 2000;87(4):463-467
Malignant melanoma in patients with multiple endocrine neoplasia type 1 and involvement of the MEN1 gene in sporadic melanoma
Nord B; Platz A; Smoczynski K; Kytölä S; Robertson G; Calender A; Murat A; Weintraub D; Burgess J; Edwards M; Skogseid B; Owen D; Lassam N; Hogg D; Larsson C; Teh BT
Article: AMERICAN JOURNAL OF PATHOLOGY. 2000;157(2):579-586
Patterns of chromosomal imbalances in parathyroid carcinomas
Kytölä S; Farnebo F; Obara T; Isola J; Grimelius L; Farnebo LO; Sandelin K; Larsson C
Article: CLINICAL ENDOCRINOLOGY. 2000;53(2):205-211
Phenotype and phenocopy: the relationship between genotype and clinical phenotype in a single large family with multiple endocrine neoplasia type 1 (MEN 1)
Burgess JR; Nord B; David R; Greenaway TM; Parameswaran V; Larsson C; Shepherd JJ; Teh BT
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2000;6(2):161-169
Expression of genes involved with cell cycle control, cell growth and chromatin modification are altered in hepatoblastomas
Gray SG; Hartmann W; Eriksson T; Ekström C; Holm S; Kytölä S; von Schweinitz D; Pietsch T; Larsson C; Kogner P; Sandstedt B; Ekström TJ
Article: CLINICAL ENDOCRINOLOGY. 2000;53(1):85-92
Loss of heterozygosity in sporadic parathyroid tumours:: involvement of chromosome 1 and the MEN1 gene locus in 11q13.
Dwight T; Twigg S; Delbridge L; Wong FK; Farnebo F; Richardson AL; Nelson A; Zedenius J; Philips J; Larsson C; Teh BT; Robinson B
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2000;6(1):73-81
Characterization of the human peroxisome proliferator activated receptor delta gene and its expression
Skogsberg J; Kannisto K; Roshani L; Gagné E; Hamsten A; Larsson C; Ehrenborg E
Article: GENES CHROMOSOMES & CANCER. 2000;28(3):308-317
Chromosomal alterations in 15 breast cancer cell lines by comparative genomic hybridization and spectral karyotyping
Kytölä S; Rummukainen J; Nordgren A; Karhu R; Farnebo F; Isola J; Larsson C
Article: CLEFT PALATE CRANIOFACIAL JOURNAL. 2000;37(4):357-362
Linkage analysis of candidate regions in Swedish nonsyndromic cleft lip with or without cleft palate families
Wong FK; Hagberg C; Karsten A; Larson O; Gustavsson M; Huggare J; Larsson C; Teh BT; Linder-Aronson S
Article: CANCER GENETICS. 2000;119(2):109-112
Balanced translocation (3;7)(p25;q34):: Another mechanism of tumorigenesis in follicular thyroid carcinoma?
Lui WO; Kytölä S; Ånfalk L; Larsson C; Farnebo LO
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2000;142(6):643-649
Expression of RET and its ligand complexes, GDNF/GFRalpha-1 and NTN/GFRalpha-2, in medullary thyroid carcinomas
Frisk T; Farnebo F; Zedenius J; Grimelius L; Höög A; Wallin G; Larsson C
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2000;5(5):485-492
New chromosomal breakpoints in non-Hodgkin's lymphomas revealed by spectral karyotyping and G-banding
Nordgren A; Sorensen AG; Tinggaard-Pedersen N; Blennow E; Larsson C; Lagercrantz S
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2000;85(4):1449-1454
A genotypic and histopathological study of a large Dutch kindred with hyperparathyroidism-jaw tumor syndrome
Haven CJ; Wong FK; van Dam EWCM; van der Luijt R; van Asperen C; Jansen J; Rosenberg C; de Wit M; Roijers J; Hoppener J; Lips CJ; Larsson C; Teh BT; Morreau H
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2000;5(3):235-240
Spectral karyotyping and chromosome banding studies of primary breast carcinomas and their lymph node metastases
Adeyinka A; Kytölä S; Mertens F; Pandis N; Larsson C
Article: AMERICAN JOURNAL OF PATHOLOGY. 2000;156(2):651-659
Comparative genomic hybridization reveals frequent losses of chromosomes 1p and 3q in pheochromocytomas and abdominal paragangliomas, suggesting a common genetic etiology
Edström E; Mahlamäki E; Nord B; Kjellman M; Karhu R; Höög A; Goncharov N; Teh BT; Bäckdahl M; Larsson C
Article: HEMATOLOGY JOURNAL. 2000;1(2):95-101
Detailed characterization of a complex karyotype in a patient with primary plasma cell leukaemia using multicolour spectral karyotyping and micro-FISH.
Nordgren A; Farnebo F; Björkholm M; Sahlén S; Porwit-MacDonald A; Osby E; Kytölä S; Larsson C; Nordenskjöld M; Blennow E
Article: MAMMALIAN GENOME. 2000;11(1):78-80
Molecular characterization of human and murine C11orf5, a new member of the FAUNA gene cluster
Lemmens IH; Farnebo F; Piehl F; Merregaert J; Van de Ven WJM; Larsson C; Kas K
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2000;5(1):33-41
Modulating IGFBP-3 expression by trichostatin A:: Potential therapeutic role in the treatment of hepatocellular carcinoma
Gray SG; Kytölä S; Lui WO; Larsson C; Ekström TJ
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2000;85(1):165-167
Familial isolated hyperparathyroidism as a variant of multiple endocrine neoplasia type 1 in a large Danish pedigree
Kassem M; Kruse TA; Wong FK; Larsson C; Teh BT
Article: NEUROLOGY. 1999;53(6):1265-1271
Mapping of autosomal dominant progressive external ophthalmoplegia to a 7-cM critical region on 10q24
Li FY; Tariq M; Croxen R; Morten K; Squier W; Newsom-Davis J; Beeson D; Larsson C
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 1999;84(10):3775-3780
Alternative genetic pathways in parathyroid tumorigenesis
Farnebo F; Kytölä S; Teh BT; Dwight T; Wong FK; Höög A; Elvius M; Wassif WS; Thompson NW; Farnebo LO; Sandelin K; Larsson C
Article: GENES CHROMOSOMES & CANCER. 1999;26(1):35-39
Sporadic follicular thyroid tumors show loss of a 200-kb region in 11q13 without evidence for mutations in the MEN1 gene
Nord B; Larsson C; Wong FK; Wallin G; Teh BT; Zedenius J
Article: GENES CHROMOSOMES & CANCER. 1999;25(4):349-353
Low frequency of numerical chromosomal aberrations in follicular thyroid tumors detected by comparative genomic hybridization
Frisk T; Kytölä S; Wallin G; Zedenius J; Larsson C
Article: FEBS LETTERS. 1999;450(3):210-216
Suppression of the neoplastic phenotype by transfection of phospholipase C β 3 to neuroendocrine tumor cells
Stålberg P; Wang S; Larsson C; Weber C; Öberg K; Gobl A; Skogseid B
Article: MAMMALIAN GENOME. 1999;10(4):376-380
Characterization and chromosomal localization of the human insulin-like growth factor binding protein 6 gene
Ehrenborg E; Zazzi H; Lagercrantz S; Granqvist M; Hillerbrand U; Allander SV; Larsson C; Luthman H
Article: ACTA ODONTOLOGICA SCANDINAVICA. 1999;57(2):72-76
Clinical and genetic studies of Van der Woude syndrome in Sweden
Wong FK; Karsten A; Larson O; Huggare J; Hagberg C; Larsson C; Teh BT; Linder-Aronson S
Article: WORLD JOURNAL OF SURGERY. 1999;23(3):237-242
Gelatinase A and membrane-type 1 matrix metalloproteinase mRNA:: Expressed in adrenocortical cancers but not in adenomas
Kjellman M; Enberg U; Höög A; Larsson C; Holst M; Farnebo LO; Sato H; Bäckdahl M
Article: CLINICAL ENDOCRINOLOGY. 1999;50(3):343-346
No overrepresentation of congenital adrenal hyperplasia in patients with adrenocortical tumours
Kjellman M; Holst M; Bäckdahl M; Larsson C; Farnebo LO; Wedell A
Article: GENES CHROMOSOMES & CANCER. 1999;24(3):175-182
Distinct deleted regions on chromosome segment 16q23-24 associated with metastases in prostate cancer
Li CD; Berx G; Larsson C; Auer G; Aspenblad U; Pan Y; Sundelin B; Ekman P; Nordenskjöld M; van Roy F; Bergerheim USR
Article: CLINICAL ENDOCRINOLOGY. 1999;50(2):191-196
Genetic studies of a family with hereditary hyperparathyroidism jaw tumour syndrome
Wassif WS; Farnebo F; Teh BT; Moniz CF; Li FY; Harrison JD; Peters TJ; Larsson C; Harris P
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 1999;84(2):730-735
Genotyping of adrenocortical tumors:: Very frequent deletions of the MEN1 locus in 11q13 and of a 1-centimorgan region in 2p16
Kjellman M; Roshani L; Teh BT; Kallioniemi OP; Höög A; Gray S; Farnebo LO; Holst M; Bäckdahl M; Larsson C
Article: WORLD JOURNAL OF SURGERY. 1999;23(1):68-74
Evaluation of retinoblastoma and Ki-67 immunostaining as diagnostic markers of benign and malignant parathyroid disease
Farnebo F; Auer G; Farnebo LO; Teh BT; Twigg S; Aspenblad U; Thompson NW; Grimelius L; Larsson C; Sandelin K
Article: CYTOGENETIC AND GENOME RESEARCH. 1999;87(3-4):225-232
Characterization of chromosomal abnormalities in prostate cancer cell lines by spectral karyotyping
Pan Y; Kytölä S; Farnebo F; Wang N; Lui WO; Nupponen N; Isola J; Visakorpi T; Bergerheim USR; Larsson C
Article: FEBS LETTERS. 1998;441(2):261-265
Targeted disruption of the mouse phospholipase C β3 gene results in early embryonic lethality
Wang S; Gebre-Medhin S; Betsholtz C; Stålberg P; Zhou YH; Larsson C; Weber G; Feinstein R; Öberg K; Gobl A; Skogseid B
Article: ONCOGENE. 1998;17(19):2485-2493
Characterization of the mouse Men1 gene and its expression during development
Stewart C; Parente F; Piehl F; Farnebo F; Quincey D; Silins G; Bergman L; Carle GF; Lemmens I; Grimmond S; Xian CZ; Khodei S; Teh BT; Lagercrantz J; Siggers P; Calender A; Van de Vem V; Kas K; Weber G; Hayward N; Gaudray P; Larsson C
Article: GENOMICS. 1998;52(2):245-246
Human histone deacetylase 2, HDAC2 (human RPD3), is localized to 6q21 by radiation hybrid mapping
Betz R; Gray SG; Ekström C; Larsson C; Ekström TJ
Article: GENOMICS. 1998;52(2):201-204
Restriction map of a YAC and cosmid contig encompassing the oculopharyngeal muscular dystrophy candidate region on chromosome 14q11.2-q13
Xie YG; Rochefort D; Brais B; Howard H; Han FY; Gou LP; Maciel P; The BT; Larsson C; Rouleau GA
Article: MAMMALIAN GENOME. 1998;9(8):660-665
Expression and chromosomal localization of the Requiem gene
Gabig TG; Crean CD; Klenk A; Long HY; Copeland NG; Gilbert DJ; Jenkins NA; Quincey D; Parente F; Lespinasse F; Carle GF; Gaudray P; Zhang CX; Calender A; Hoeppener J; Kas K; Thakker RV; Farnebo F; Teh BT; Larsson C; Piehl F; Lagercrantz J; Khodaei S; Carson E; Weber G
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 1998;83(8):2627-2630
Alterations of the MEN1 gene in sporadic parathyroid tumors
Farnebo F; Teh BT; Kytölä S; Svensson A; Phelan C; Sandelin K; Thompson NW; Höög A; Weber G; Farnebo LO; Larsson C
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 1998;83(8):2621-2626
Mutation analysis of the MEN1 gene in multiple endocrine neoplasia type 1, familial acromegaly and familial isolated hyperparathyroidism
Teh BT; Kytölä S; Farnebo F; Bergman L; Wong FK; Weber G; Hayward N; Larsson C; Skogseid B; Beckers A; Phelan C; Edwards M; Epstein M; Alford F; Hurley D; Grimmond S; Silins G; Walters M; Stewart C; Cardinal J; Khodaei S; Parente F; Tranebjaerg L; Jorde R; Menon J; Khir A; Tan TT; Chan SP; Zaini A; Khalid BAK; Sandelin K; Thompson N; Brandi ML; Warth M; Stock J; Leisti J; Cameron D; Shepherd JJ; Öberg K; Nordenskjöld M; Salmela P
Article: ANNALS OF SURGERY. 1998;228(1):99-105
Thymic carcinoids in multiple endocrine neoplasia type 1
Teh BT; Zedenius J; Kytölä S; Skogseid B; Trotter J; Choplin H; Twigg S; Farnebo F; Giraud S; Cameron D; Robinson B; Calender A; Larsson C; Salmela P
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1998;247(2):357-360
Expression of the BCL6 gene in the pre- and postnatal mouse
Bajalica-Lagercrantz S; Piehl F; Farnebo F; Larsson C; Lagercrantz J
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 1998;1398(2):157-163
A comparative study of the expression patterns for vegf, vegf-b/vrf and vegf-c in the developing and adult mouse
Lagercrantz J; Farnebo F; Larsson C; Tvrdik T; Weber G; Piehl F
Article: GENOMICS. 1998;50(2):251-259
A putative human zinc-finger gene (ZFPL1) on 11q13, highly conserved in the mouse and expressed in exocrine pancreas -: The European Consortium on MEN 1
Höppener JWM; De Wit MJ; Simarro-Doorten AY; Roijers JFM; van Herrewaarden HMC; Lips CJM; Parente F; Quincey D; Gaudray P; Khodaei S; Weber G; Teh B; Farnebo F; Larsson C; Zhang CX; Calender A; Pannett AAJ; Forbes SA; Bassett JHT; Thakker RV; Lemmens I; Van de Ven WJM; Kas K
Article: GENOMICS. 1998;50(2):213-221
Cloning and characterization of ZNF189, a novel human Kruppel-like zinc finger gene localized to chromosome 9q22-q31
Odeberg J; Rosok O; Gudmundsson GH; Ahmadian A; Roshani L; Williams C; Larsson C; Pontén F; Uhlén M; Åsheim HC; Lundeberg J
Article: DIABETES. 1998;47(6):976-979
Insulin receptor substrate-2 amino acid polymorphisms are not associated with random type 2 diabetes among Caucasians
Bernal D; Almind K; Yenush L; Ayoub M; Zhang YT; Rosshani L; Larsson C; Pedersen O; White MF
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 1998;83(6):2114-2120
Familial isolated hyperparathyroidism maps to the hyperparathyroidism-jaw tumor locus in 1q21-q32 in a subset of families
Teh BT; Farnebo F; Twigg S; Höög A; Kytölä S; Korpi-Hyövälti E; Wong FK; Nordenström J; Grimelius L; Sandelin K; Robinson B; Farnebo LO; Larsson C
Article: NEUROLOGY. 1998;50(4):1067-1073
Charcot-Marie-Tooth disease and Noonan syndrome with giant proximal nerve hypertrophy
Silburn PA; Nicholson GA; Teh BT; Blair IP; Pollard JD; Nolan PJ; Larsson C; Boyle RS
Article: MAMMALIAN GENOME. 1998;9(4):310-311
Mapping of the human Ca²⁺ channel β₄ subunit to 2q22-23 and its expression in developing mouse
Betz R; Leibiger B; Farnebo F; Lagercrantz S; Piehl F; Leibiger I; Larsson C
Article: CANCER RESEARCH. 1998;58(5):1004-1012
Consortium study on 1280 breast carcinomas:: Allelic loss on chromosome 17 targets subregions associated with family history and clinical parameters
Phelan CM; Borg Å; Cuny M; Crichton DN; Baldersson T; Andersen TI; Caligo MA; Lidereau R; Lindblom A; Seitz S; Kelsell D; Hamann K; Rio P; Thorlacius S; Papp J; Olah E; Ponder B; Bignon YJ; Scherneck S; Barkardottir R; Borresen-Dale AL; Eyfjörd J; Theillet C; Thompson AM; Devilee P; Larsson C
Article: GENES CHROMOSOMES & CANCER. 1998;21(3):260-264
Bilateral multiple renal oncocytomas and cysts associated with a constitutional translocation (8;9)(q24.1;q34.3) and a rare constitutional VHL missense substitution
Teh BT; Blennow E; Giraud S; Sahlen S; Hii SI; Brookwell R; Nordenskjold HM; Larsson C; Nicol D
Article: ONCOGENE. 1998;16(4):481-487
Identification of two distinct deleted regions on chromosome 13 in prostate cancer
Li CD; Larsson C; Futreal A; Lancaster J; Phelan C; Aspenblad U; Sundelin B; Liu Y; Ekman P; Auer G; Bergerheim USR
Article: CANCER EPIDEMIOLOGY. 1998;22(6):544-548
A rapid method for DNA extraction from fine-needle aspiration biopsies of thyroid tumors, and subsequent RET mutation analysis
Zedenius J; Dwight T; Robinson BG; Delbridge L; Backdahl M; Wallin G; Larsson C; Weber G
Article: GENOMICS. 1997;46(1):78-85
Cloning and characterization of freac-9 (FKHL17), a novel kidney-expressed human forkhead gene that maps to chromosome 1p32-p34
Ernstsson S; Betz R; Lagercrantz S; Larsson C; Ericksson S; Cederberg A; Carlsson P; Enerback S
Article: CANCER RESEARCH. 1997;57(21):4710-4713
Somatic deletions and mutations in the Cowden disease gene, PTEN, in sporadic thyroid tumors
Dahia PLM; Marsh DJ; Zheng ZM; Zedenius J; Komminoth P; Frisk T; Wallin G; Parsons R; Longy M; Larsson C; Eng C
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1997;239(3):878-883
Novel splicing of an IGF2 polymorphic region in Human adrenocortical carcinomas
Gray SG; Kjellman M; Larsson C; Ekstrom TJ
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 1997;82(10):3481-3486
Tumor-specific decreased expression of calcium sensing receptor messenger ribonucleic acid in sporadic primary hyperparathyroidism
Farnebo F; Enberg U; Grimelius L; Backdahl M; Schalling M; Larsson C; Farnebo LO
Article: HUMAN GENETICS. 1997;100(5-6):657-665
The European Consortium on MEN1 - Linkage disequilibrium studies in multiple endocrine neoplasia type 1 (MEN1)
Bassett JHD; Pannett AAJ; Forbes SA; Thakker RV; McCarthy M; Read AP; Teh BT; Larsson C; Kytola S; Leisti J; Salmela P; Weber G; Giraud S; Zhang CX; Calender A; Hoppener JWM; vanAmstel HKP; Lips CJM; Kas K; VandeVen WJM; Gaudray P
Article: GENOMICS. 1997;44(3):344-346
Chromosome localization, sequence analysis, and expression pattern identify FKHL 18 as a novel human forkhead gene
Cederberg A; Betz R; Lagercrantz S; Larsson C; Hulander M; Carlsson P; Enerback S
Article: GENOMICS. 1997;44(1):94-100
Construction of a 1.2-Mb sequence-ready contig of chromosome 11q13 encompassing the multiple endocrine neoplasia type 1 (MEN1) gene - The European consortium on type 1 (MEN1) gene
Lemmens I; Merregaert J; VandeVen WJM; Kas K; Zhang CX; Giraud S; Wautot V; Buisson N; DeWitte K; Salandre J; Lenoir G; Calender A; Parente F; Quincey D; Courseaux A; Carle GF; Gaudray P; DeWit MJ; Lips CJM; Hoppener JWM; Khodaei S; Grant AL; Weber G; Kytola S; Teh BT; Farnebo F; Grimmond S; Phelan C; Larsson C; Forbes SA; Bassett JHD; Pannett AAJ; Thakker RV
Article: HUMAN GENETICS. 1997;100(3-4):481-485
Mapping of the gene encoding the B56 beta subunit of protein phosphatase 2A (PPP2R5B) to a 0.5-Mb region of chromosome 11q13 and its exclusion as a candidate gene for multiple endocrine neoplasia type 1 (MEN1)
Forbes SA; Pannett AAJ; Bassett JHD; Harding B; Wooding C; Thakker RV; Butler R; Ogilvie D; Anand R; Gaudray P; Weber G; Larsson C; Zhang CX; Calender A; Hoppener JWM; Lips CJM; Kas K
Article: HUMAN MOLECULAR GENETICS. 1997;6(7):1177-1183
Identification of the multiple endocrine neoplasia type 1 (MEN1) gene
Lemmens I; VandeVen WJM; Kas K; Zhang CX; Giraud S; Wautot V; Buisson N; DeWitte K; Salandre J; Lenoir G; Pugeat M; Calender A; Parente F; Quincey D; Gaudray P; DeWit MJ; Lips CJM; Hoppener JWM; Khodaei S; Grant AL; Weber G; Kytola S; Teh BT; Farnebo F; Phelan C; Hayward N; Larsson C; Pannett AAJ; Forbes SA; Bassett JHD; Thakker RV
Article: MAMMALIAN GENOME. 1997;8(7):513-515
The mouse homologs of RELA and MLK3 are located within a 120-kb fragment on Chromosome 19
Fernandes M; Poirier C; Lassam NJ; Larsson C; Guenet JL; Gaudray P; Carle GF
Article: HUMAN GENETICS. 1997;99(6):776-780
Fine mapping of the MLK-3 gene within 11q13 and its exclusion as the MEN1 susceptibility gene
Lassam NJ; Lin Z; Shennan MG; Courseaux A; Teh BT; Gaudray P; Larsson C
Article: BRITISH JOURNAL OF SURGERY. 1997;163(5):331-337
Allelic loss on chromosome 11 is uncommon in parathyroid glands of patients with hypercalcaemic secondary hyperparathyroidism
Farnebo F; Farnebo LO; Nordenstrom J; Larsson C
Article: JOURNAL OF CLINICAL NEUROSCIENCE. 1997;4(2):176-180
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy
Sullivan AA; Teh BT; Jeavons S; Schalling M; Silburn P; Larsson C; Boyle R
Article: LANCET. 1997;349(9055):848-849
Familial non-VHL non-papillary clear-cell renal cancer
Teh BT; Giraud S; Sari NF; Hii SI; Bergerat JP; Larsson C; Limacher JM; Nicol D
Article: HUMAN GENETICS. 1997;99(3):342-349
Differential loss of heterozygosity in familial, sporadic, and uremic hyperparathyroidism
Farnebo F; Teh BT; Dotzenrath C; Wassif WS; Svensson A; White I; Betz R; Goretzki P; Sandelin K; Farnebo LO; Larsson C
Article: CANCER RESEARCH. 1997;57(3):500-503
Differential loss of heterozygosity in the region of the Cowden locus within 10q22-23 in follicular thyroid adenomas and carcinomas
Marsh DJ; Zheng ZM; Zedenius J; Kremer H; Padberg GW; Larsson C; Longy M; Eng C
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 1997;82(2):486-492
A kindred with a variant of multiple endocrine neoplasia type 1 demonstrating frequent expression of pituitary tumors but not linked to the multiple endocrine neoplasia type 1 locus at chromosome region 11q13
Stock JL; Warth MR; Teh BT; Coderre JA; Overdorf JH; Baumann G; Hintz RL; Hartman ML; Seizinger BR; Larsson C; Aronin N
Article: CLINICAL GENETICS. 1997;51(1):52-55
Oculopharyngeal muscular dystrophy (OPMD) - Report and genetic studies of an Australian kindred
Teh BT; Sullivan AA; Farnebo F; Zander C; Li FY; Strachan N; Schalling M; Larsson C; Sandstrom P
Article: ACTA DERMATO-VENEREOLOGICA. 1997;77(1):4-9
Fine mapping of the locus for nevoid basal cell carcinoma syndrome on chromosome 9q
Unden AB; StahleBackdahl M; Holmberg E; Larsson C; Toftgard R
Article: MEDICINE. 1997;76(1):21-29
Clinicopathologic studies of thymic carcinoids in multiple endocrine neoplasia type 1
Teh BT; McArdle J; Chan SP; Menon J; Hartley L; Pullan P; Ho J; Khir A; Wilkinson S; Larsson C; Cameron D; Shepherd J
Article: HUMAN GENETICS. 1996;99(1):130-132
Exclusion of the phosphoinositide-specific phospholipase C beta 3 (PLCB3) gene as a candidate for multiple endocrine neoplasia type 1
Weber G; Grimmond S; Lagercrantz J; Friedman E; Phelan C; Carson E; Hayward N; Jacobovitz O; Nordenskjold M; Larsson C
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 1996;81(12):4204-4211
Autosomal dominant primary hyperparathyroidism and jaw tumor syndrome associated with renal hamartomas and cystic kidney disease: Linkage to 1q21-q32 and loss of the wild type allele in renal hamartomas
Teh BT; Farnebo F; Kristoffersson U; Sundelin B; Cardinal J; Axelson R; Yap A; Epstein M; Heath H; Cameron D; Larsson C
Article: GENOMICS. 1996;37(3):354-365
Definition of the minimal MEN1 candidate area based on a 5-Mb integrated map of proximal 11q13. The European Consortium on Men1, (GENEM 1; Groupe d'Etude des Néoplasies Endocriniennes Multiples de type 1).
Courseaux A; Grosgeorge J; Gaudray P; Pannett AA; Forbes SA; Williamson C; Bassett D; Thakker RV; Teh BT; Farnebo F; Shepherd J; Skogseid B; Larsson C; Giraud S; Zhang CX; Salandre J; Calender A
Article: ARCHIVES OF SURGERY. 1996;131(11):1230-1232
Sporadic primary hyperparathyroidism in the setting of multiple endocrine neoplasia type 1
Teh BT; McArdle J; Parameswaran V; David R; Larsson C; Shepherd J
Article: CANCER RESEARCH. 1996;56(18):4219-4223
Genetic aberrations in adrenocortical tumors detected using comparative genomic hybridization correlate with tumor size and malignancy
Kjellman M; Kallioniemi OP; Karhu R; Hoog A; Farnebo LO; Auer G; Larsson C; Backdahl M
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 1996;81(9):3194-3196
Allelic loss of the retinoblastoma tumor suppressor gene: A marker for aggressive parathyroid tumors?
Dotzenrath C; Teh BT; Farnebo F; Cupisti K; Svensson A; Toell A; Goretzki P; Larsson C
Article: GENOMICS. 1996;35(3):633-635
A human homologue of the rat rab geranylgeranyl transferase beta subunit on chromosome 1p22-p31
Sanders R; BinIslam K; Betz R; Larsson C; Smith CIE
Article: GENOMICS. 1996;34(1):63-68
The human mammary-derived growth inhibitor (MDGI) gene: Genomic structure and mutation analysis in human breast tumors
Phelan CM; Larsson C; Baird S; Futreal PA; Ruttledge MH; Morgan K; Tonin P; Hung H; Korneluk RG; Pollak MN; Narod SA
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 1996;81(4):1312-1317
Clustered inactivating mutations and benign polymorphisms of the calcium receptor gene in familial benign hypocalciuric hypercalcemia suggest receptor functional domains
Heath H; Odelberg S; Jackson CE; Teh BT; Hayward N; Larsson C; Buist NRM; Krapcho KJ; Hung BC; Capuano IV; Garrett JE; Leppert MF
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1996;220(1):147-152
Expression of the VEGF-related factor gene in pre- and postnatal mouse
Lagercrantz J; Larsson C; Grimmond S; Fredriksson M; Weber G; Piehl F
Article: HUMAN GENETICS. 1996;97(3):299-303
Deletions of the long arm of chromosome 10 in progression of follicular thyroid tumors
Zedenius J; Wallin G; Svensson A; Bovee J; Hoog A; Backdahl M; Larsson C
Article: GENOMICS. 1996;31(3):380-384
Isolation and characterization of a novel gene close to the human phosphoinositide-specific phospholipase C beta 3 gene on chromosomal region 11q13
Lagercrantz J; Carson E; Larsson C; Nordenskjold M; Weber G
Article: THYROID. 1996;6(1):1-9
Alterations of p53 and expression of WAF1/p21 in human thyroid tumors
Zedenius J; Larsson C; Wallin G; Backdahl M; Aspenblad U; Hoog A; Borresen AL; Auer G
Article: WORLD JOURNAL OF SURGERY. 1996;20(1):101-106
Stromal fibroblasts adjacent to invasive thyroid tumors: Expression of gelatinase a but not stromelysin 3 mRNA
Zedenius J; StahleBackdahl M; Enberg U; Grimelius L; Larsson C; Wallin G; Backdahl M
Article: NEUROREPORT. 1995;6(18):2542-2544
Expression of the phosphoinositide-specific phospholipase C beta 3 gene in the rat
Lagercrantz J; Piehl F; Nordenskjold M; Larsson C; Weber G
Article: GENOMICS. 1995;30(3):464-469
Chromosomal localization of six human forkhead genes, freac-1(FKHL5), -3(FKHL7), -4(FKHL8), -5(FKHL9), -6(FKHL10), and -8(FKHL12)
Larsson C; Hellqvist M; Pierrou S; White I; Enerback S; Carlsson P
Article: SURGERY. 1995;118(6):1077-1082
ADRENAL LESION IN MULTIPLE ENDOCRINE NEOPLASIA TYPE-1
SKOGSEID B; RASTAD J; GOBL A; LARSSON C; BACKLIN K; JUHLIN C; AKERSTROM G; OBERG K
Article: SURGERY. 1995;118(6):924-930
HYPERPARATHYROIDISM OF MULTIPLE ENDOCRINE NEOPLASIA TYPE-1 - CANDIDATE GENE AND PARATHYROID CALCIUM SENSING PROTEIN EXPRESSION
CARLING T; RASTAD J; RIDEFELT P; GOBL A; HELLMAN P; OBERG K; RASK L; LARSSON C; JUHLIN C; AKERSTROM G; SKOGSEID B
Article: JOURNAL OF INTERNAL MEDICINE. 1995;238(3):249-253
GENETIC-MAPPING OF THE MULTIPLE ENDOCRINE NEOPLASIA TYPE-1 LOCUS AT 11Q13
TEH BT; CARDINAL J; SHEPHERD J; HAYWARD NK; WEBER G; CAMERON D; LARSSON C
Article: JOURNAL OF INTERNAL MEDICINE. 1995;238(3):245-248
CANDIDATE GENES FOR MULTIPLE ENDOCRINE NEOPLASIA TYPE-1
LAGERCRANTZ J; LARSSON C; GRIMMOND S; SKOGSEID B; GOBL A; FRIEDMAN E; CARSON E; PHELAN C; OBERG K; NORDENSKJOLD M; HAYWARD NK; WEBER G
Article: JOURNAL OF INTERNAL MEDICINE. 1995;238(3):239-244
MOLECULAR TOOLS FOR PRESYMPTOMATIC TESTING IN MULTIPLE ENDOCRINE NEOPLASIA TYPE-1
LARSSON C; CALENDER A; GRIMMOND S; GIRAUD S; HAYWARD NK; TEH B; FARNEBO F
Article: LEUKEMIA. 1995;9(8):1313-1317
REARRANGEMENT OF PROXIMAL 11Q13 BAND IN A CMML IN ACUTE TRANSFORMATION
COURSEAUX A; GROSGEORGE J; GARNIER G; LARSSON C; AYRAUD N; GAUDRAY P; RAYNAUD SD
Article: HUMAN GENETICS. 1995;96(1):27-32
ALLELOTYPING OF FOLLICULAR THYROID-TUMORS
ZEDENIUS J; WALLIN G; SVENSSON A; GRIMELIUS L; HOOG A; LUNDELL G; BACKDAHL M; LARSSON C
Article: GENES CHROMOSOMES & CANCER. 1995;13(3):203-210
HIGH ALLELE LOSS RATES AT 17Q12-Q21 IN BREAST AND OVARIAN-TUMORS FROM BRCA1-LINKED FAMILIES
CORNELIS RS; NEUHAUSEN SL; JOHANSSON O; ARASON A; KELSELL D; PONDER BAJ; TONIN P; HAMANN U; LINDBLOM A; LALLE P; LONGY M; OLAH E; SCHERNECK S; BIGNON YJ; SOBOL H; CHANGCLAUDE J; LARSSON C; SPURR N; BORG A; BARKARDOTTIR RB; NAROD S; DEVILEE P
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 1995;56(6):1443-1449
FAMILIAL PERIODIC CEREBELLAR-ATAXIA WITHOUT MYOKYMIA MAPS TO A 19-CM REGION ON 19P13
TEH BT; SILBURN P; LINDBLAD K; BETZ R; BOYLE R; SCHALLING M; LARSSON C
Article: GENOMICS. 1995;26(3):467-472
GENOMIC ORGANIZATION AND COMPLETE CDNA SEQUENCE OF THE HUMAN PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE-C BETA-3 GENE (PLCB3)
LAGERCRANTZ J; CARSON E; PHELAN C; GRIMMOND S; ROSEN A; DARE E; NORDENSKJOLD M; HAYWARD NK; LARSSON C; WEBER G
Article: JOURNAL OF IMMUNOLOGY. 1995;154(3):1265-1272
MOLECULAR-CLONING, CHARACTERIZATION, AND CHROMOSOMAL LOCALIZATION OF A HUMAN LYMPHOID TYROSINE KINASE RELATED TO MURINE BLK
ISLAM KB; RABBANI H; LARSSON C; SANDERS R; SMITH CIE
Article: LAKARTIDNINGEN. 1995;92(4):269-275
[The first breast cancer gene isolated. Safer risk assessment for affected families].
Iselius L; Larsson C; Lindblom A; Sandelin K; Wickman M; Wilking N
Article: CYTOGENETIC AND GENOME RESEARCH. 1995;71(3):257-259
ASSIGNMENT OF THE MOUSE HOMOLOG OF A HUMAN MEN1 CANDIDATE GENE, PHOSPHOLIPASE C-BETA-3 (PLCB3), TO CHROMOSOME REGION 19B BY FISH
GOBL AE; CHOWDHARY BP; SHU W; ERIKSSON L; LARSSON C; WEBER G; OBERG K; SKOGSEID B
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 1995;56(1):254-264
AN EVALUATION OF GENETIC-HETEROGENEITY IN 145 BREAST-CANCER OVARIAN-CANCER FAMILIES
NAROD SA; FORD D; DEVILEE P; BARKARDOTTIR RB; LYNCH HT; SMITH SA; PONDER BAJ; WEBER BL; GARBER JE; BIRCH JM; CORNELIS RS; KELSELL DP; SPURR NK; SMYTH E; HAITES N; SOBOL H; BIGNON YJ; CHANGCLAUDE J; HAMANN U; LINDBLOM A; BORG A; PIVER MS; GALLION HH; STRUEWING JP; WHITTEMORE A; TONIN P; GOLDGAR DE; EASTON DF; MILNER B; ALLAN L; SIMARD J; ROMMENS J; MCGILLIVRAY B; GREEN R; IVES E; BOYD N; ROSEN B; COLE D; MORGAN K; MOSLEHI R; PONDER B; PETO J; SMITH S; STRATTON M; DICIOCCIO RA; GALLION H; SANTIBANEZKOREF MS; TEARE MD; EVANS DG; STOPPALYONNET D; LALLE P; BONAITI C; ESSIOUX L; GIRODET C; MAUGARDLOUBOUTIN C; NICOLLEAU G; LONGY M; TOULOUSE C; HORSTEIN I; BIRNBAUM D; EISINGER F; KARENGUEVEN F; NOGUCHI T; HARDOUIN A; RIO P; MACHELARDROUMAGNAC M; NOGUES C; COHENHAGUENAUER O; LORTHOLARY A; BAY JO; ARASON A; BARKDARDOTTIR RB; EGILSSON V; BISHOP DT; KELSELL D; MURDAY VA; SOLOMON E; SPURR N; TURNER G; LENOIR G; FEUNTEUN J; LYNCH H; LYNCH J; WATSON P; CONWAY T; BONNARDEL C; SEROVA O; TORCHARD D; LARSSON C; VASEN H; VANLEEUWEN I; CORNELISSE CJ; STEEL M; PORTER D; COHEN BB; CAROTHERS A; CANNONALBRIGHT LA; GOLDGAR D; SKOLNICK M; BECHER H; JOHANNSSON O; WEBER B; COLLINS F; BOEHNKE M; GARBER J; LI F
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 1992;33(4):861-869
Gene-specific promoter hypermethylation without global hypomethylation in follicular thyroid cancer
Lee J-J; Geli J; Larsson C; Wallin G; Karimi M; Zedenius J; Hoog A; Foukakis T
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 1992;34(2):481-492
Loss of expression for the Wnt pathway components adenomatous polyposis coli and glycogen synthase kinase 3-β in parathyroid carcinomas
Juhlin CC; Haglund F; Villablanca A; Forsberg L; Sandelin K; Branstrom R; Larsson C; Hoog A
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Corrigendum: NATURE METABOLISM. 2022;4(10):1421
Impaired oxygen-sensitive regulation of mitochondrial biogenesis within the von Hippel-Lindau syndrome (June, 10.1038/s42255-022-00593-x, 2022)
Li S; Li W; Yuan J; Bullova P; Wu J; Zhang X; Liu Y; Plescher M; Rodriguez J; Bedoya-Reina OC; Jannig PR; Valente-Silva P; Yu M; Henriksson MA; Zubarev RA; Smed-Sorensen A; Suzuki CK; Ruas JL; Holmberg J; Larsson C; Christofer Juhlin C; von Kriegsheim A; Cao Y; Schlisio S
Review: LANCET DIABETES & ENDOCRINOLOGY. 2021;9(1):13-21
Maternal and fetal outcomes in phaeochromocytoma and pregnancy: a multicentre retrospective cohort study and systematic review of literature.
Bancos I; Atkinson E; Eng C; Young WF; Neumann HPH; International Pheochromocytoma and Pregnancy Study
Review: ONCOGENE. 2019;38(34):6172-6183
Mechanisms underlying the activation of TERT transcription and telomerase activity in human cancer: old actors and new players
Yuan X; Larsson C; Xu D
Letter: CLINICAL ENDOCRINOLOGY. 2018;88(2):343-345
Telomerase reverse transcriptase promoter hypermethylation is associated with metastatic disease in abdominal paraganglioma
Svahn F; Juhlin CC; Paulsson JO; Fotouhi O; Zedenius J; Larsson C; Stenman A
Published conference paper: SURGERY. 2017;161(6):1667-1674
Overexpression of cytochrome P450 2A6 in adrenocortical carcinoma
Murtha TD; Brown TC; Rubinstein JC; Haglund F; Juhlin C; Larsson C; Korah R; Carling T
Letter: ENDOCRINE-RELATED CANCER. 2015;22(3):L9-L11
TERT promoter mutations are rare in parathyroid tumors
Haglund F; Juhlin CC; Brown T; Ghaderi M; Liu T; Stenman A; Dinets A; Prasad M; Korah R; Xu D; Carling T; Larsson C
Letter: CLINICAL ENDOCRINOLOGY. 2010;73(4):552-553
Lack of S37A CTNNB1/β-catenin mutations in a Swedish cohort of 98 parathyroid adenomas
Haglund F; Andreasson A; Nilsson I-L; Hoog A; Larsson C; Juhlin CC
Meeting abstract: EUROPEAN JOURNAL OF CANCER, SUPPLEMENT. 2010;8(5):224
The involvement of miR-483 and its host gene IGF2 in development of adrenal cortical carcinoma
Ozata D; Caramuta S; Akcakaya P; Xie HONG; Backdahl M; Larsson C; Lui W
Meeting abstract: EUROPEAN JOURNAL OF CANCER, SUPPLEMENT. 2010;8(5):187
Altered expression of miR-205 affects cell proliferation in human cervical cancer
Xie H; Caramuta S; Larsson C; Lui WO
Meeting abstract: EUROPEAN JOURNAL OF CANCER, SUPPLEMENT. 2010;8(5):185
Role of microRNAs and microRNA machinery in the pathogenesis of diffuse large B-cell lymphomas
Caramuta S; Berglund M; Ozata D; Akcakaya P; Georgii-Hemming P; Xie H; Enblad G; Larsson C; Lui WO
Meeting abstract: BLOOD. 2004;104(11):1540-431A
DLEU2, located within the CLL 13q14 deletion locus, encodes an antisense RNA for the putative bicistronic RFP2/LEU5 gene in humans and mouse
Corcoran MM; Hammarsund M; Zhu CY; Lerner M; Kapanadze B; Larsson C; Forsberg L; Ibbotson RE; Einhorn S; Oscier DG; Grander D; Sangfelt O
Published conference paper: WORLD JOURNAL OF SURGERY. 2002;26(8):965-971
Loss of heterozygosity on the short arm of chromosome 1 in pheochromocytoma and abdominal paraganglioma
Elder EE; Nord B; Carling T; Juhlin C; Bäckdahl M; Höög A; Larsson C
Published conference paper: WORLD JOURNAL OF SURGERY. 2002;26(8):907-913
Genetic screening for MEN1 mutations in families presenting with familial primary hyperparathyroidism
Perrier ND; Villablanca A; Larsson C; Wong M; Ituarte P; Teh BT; Clark OH
Published conference paper: BRITISH JOURNAL OF SURGERY. 2001;88(4):557-563
Expression of the RET proto-oncogene in papillary thyroid carcinoma and its correlation with clinical outcome
Kjellman P; Learoyd DL; Messina M; Weber G; Höög A; Wallin G; Larsson C; Robinson BG; Zedenius J
Letter: JOURNAL OF MEDICAL GENETICS. 2001;38(3):185-189
Founder effect in multiple endocrine neoplasia type 1 (MEN 1) in Finland
Kytölä S; Villablanca A; Ebelings T; Nord B; Larsson C; Höög A; Wong FK; Välimäki M; Vierimaa O; Teh BT; Salmela PI; Leisti J
Review: SEMINARS IN CANCER BIOLOGY. 2000;10(4):299-312
Multiple endocrine neoplasia type 1
Wong FK; Burgess J; Nordenskjöld M; Larsson C; Teh BT
Editorial comment: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2000;85(5):1752-1754
Editorial: Dissecting the genetics of hyperparathyroidism - New clues from an old friend
Larsson C
Published conference paper: SURGERY. 1999;126(6):1183-1187
Expression of matrix metalloproteinase gelatinase A messenger ribonucleic acid in parathyroid carcinomas
Farnebo F; Svensson A; Thompson NW; Bäckdahl M; Grimelius L; Larsson C; Farnebo LO; Sandelin K
Review: ANTICANCER RESEARCH. 1999;19(6A):4715-4728
Tumor suppressor genes (TSG)
Teh BT; Larsson C; Nordenskjöld M
Letter: JOURNAL OF MEDICAL GENETICS. 1999;36(4):348-349
Familial testicular cancer:: lack of evidence for trinucleotide repeat expansions and association with PKD1 in one family
Teh BT; Linblad K; Nord B; Kytölä S; Schalling M; Larsson C; Rapley E; Biggs P; Huddart R; Stratton M; Hii S; Nicol D
Published conference paper: SURGERY. 1998;124(6):1094-1099
Decreased expression of calcium-sensing receptor messenger ribonucleic acids in parathyroid adenomas
Farnebo F; Höög A; Sandelin K; Larsson C; Farnebo LO
Letter: AMERICAN JOURNAL OF HUMAN GENETICS. 1998;63(5):1544-1549
A family with isolated hyperparathyroidism segregating a missense MEN1 mutation and showing loss of the wild-type alleles in the parathyroid tumors
Teh BT; Esapa CT; Houlston R; Grandell U; Farnebo F; Nordenskjöld M; Pearce CJ; Carmichael D; Larsson C; Harris PE
Published conference paper: JOURNAL OF INTERNAL MEDICINE. 1998;243(6):441-446
The search for the MEN1 gene
Lemmes I; Van de Ven WJM; Kas K; Zhang CX; Giraud S; Wautot V; Buisson N; Pugeat M; Peix JL; Caldener A; Parente F; Quincey D; Courseaux A; Carle GF; Gaudray P; De Wit MJ; Lips CJM; Höppener JWM; Khodaei S; Grant AL; Weber G; Teh BT; Farnebo F; Kytölä S; Grimmond S; Phelan C; Larsson C; Bassett JHD; Forbes DA; Pannett AAJ; Thakker RV
Published conference paper: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 1998;841:181-183
Congenital myasthenic syndromes - Studies of the AChR and other candidate genes
Beeson D; Newland C; Croxen R; Buckel A; Li FY; Larsson C; Tariq M; Vincent A; Newsom-Davis J
Letter: AMERICAN JOURNAL OF NEURORADIOLOGY. 1997;18(5):991-992
Gene identification in autosomal dominant disorders
Teh BT; Lagercrantz J; Weber G; Larsson C
Published conference paper: HORMONE RESEARCH IN PAEDIATRICS. 1997;47(4-6):179-184
Multiple endocrine neoplasia type 1 and the search for the genetic trigger
Farnebo F; Jarhult J; Farnebo LO; Nilsson O; Teh BT; Lagercrantz J; Weber G; Sandelin K; Larsson C
Letter: NATURE GENETICS. 1996;13(2):238-240
BRCA2 mutations in primary breast and ovarian cancers
Lancaster JM; Wooster R; Mangion J; Phelan CM; Cochran C; Gumbs C; Seal S; Barfoot R; Collins N; Bignell G; Patel S; Hamoudi R; Larsson C; Wiseman RW; Berchuck A; Iglehart JD; Marks JR; Ashworth A; Stratton MR; Futreal PA
Letter: NATURE GENETICS. 1996;13(1):120-122
Mutation analysis of the BRCA2 gene in 49 site-specific breast cancer families
Phelan CM; Lancaster JM; Tonin P; Gumbs C; Cochran C; Carter R; Ghadirian P; Perret C; Moslehi R; Dion F; Faucher MC; Dole K; Karimi S; Foulkes W; Lounis H; Warner E; Goss P; Anderson D; Larsson C; Narod SA; Futreal PA
Letter: NATURE GENETICS. 1996;12(3):309-311
Ovarian cancer risk in BRCA1 carriers is modified by the HRAS1 variable number of tandem repeat (VNTR) locus
Phelan CM; Rebbeck TR; Weber BL; Devilee P; Ruttledge MH; Lynch HT; Lenoir GM; Stratton MR; Easton DF; Ponder BAJ; CannonAlbright L; Larsson C; Goldgar DE; Narod SA
Published conference paper: EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES. 1996;104:105-107
Molecular genetics of primary and secondary hyperparathyroidism
Dotzenrath C; Goretzki PE; Farnebo F; Teh BT; Weber G; Roher HD; Larsson C
Review: ANZ JOURNAL OF SURGERY. 1995;65(10):708-713
MULTIPLE ENDOCRINE NEOPLASIA TYPE-I - CLINICAL SYNDROME TO MOLECULAR-GENETICS
TEH BT; GRIMMOND S; SHEPHERD J; LARSSON C; HAYWARD N
Other: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 1995;80(10):3088-3090
MUTATIONS OF CODON-918 IN THE RET PROTOONCOGENE CORRELATE TO POOR-PROGNOSIS IN SPORADIC MEDULLARY-THYROID CARCINOMAS
ZEDENIUS J; LARSSON C; BERGHOLM U; BOVEE J; SVENSSON A; HALLENGREN B; GRIMELIUS L; BACKDAHL M; WEBER G; WALLIN G
Other: CANCER RESEARCH. 1995;55(11):2225-2231
TUMOR-SUPPRESSOR ACTIVITY OF THE GENE ENCODING MAMMARY-DERIVED GROWTH INHIBITOR
HUYNH HT; LARSSON C; NAROD S; POLLAK M
Other: HUMAN GENETICS. 1995;95(4):455-458
EXCLUSION OF THE 13-KDA RAPAMYCIN BINDING-PROTEIN GENE (FKBP2) AS A CANDIDATE GENE FOR MULTIPLE ENDOCRINE NEOPLASIA TYPE-1
GRIMMOND S; WEBER G; LARSSON C; WALTERS M; TEH B; SHEPHERD J; NORDENSKJOLD M; HAYWARD N
Other: HUMAN GENETICS. 1995;95(3):356-358
LOCALIZATION OF THE HUMAN SOLUBLE EPOXIDE HYDROLASE GENE (EPHX2) TO CHROMOSOMAL REGION 8P21-P12
LARSSON C; WHITE I; JOHANSSON C; STARK A; MEIJER J
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