Catharina Larsson

About me
Publications
CV
Public outreach and news

About me

Professor in medical genetics

Resarch group leader in medical genetics within experimental translational cancer research with laboratory activities in BioClinicum

Assistant chair of the Department of oncology-pathology with task for recruitement of teaching positions

KI chairman of the reseach &
educational development groupat ME clinical pathology &
cancer diagnostics at Karolinska university hospital

Faculty representative in the Faculty board at KI

Education
Medical degree 1985
Dr med sci at KI 1989
Docent at KI 1999
Professor in medical genetics at KI 2001

Academic honours, awards and prizes
Erik L Fernströms prize for young medical researchers 2005
Göran Gustafssons prize in Medicine 2006
Elected member of the Nobel assembly 2006
Elected member to KVA class for medical sciences 2008
Honorary doctor of medicine at Bogomolets national medical university, Ukraine 2017

Research

Basic and translational studies of tumors in endocrine organs especially the thyroid gland and the adrenals

Articles

Article: ENDOCRINE PATHOLOGY. 2024;:1-8
Catching the Silent Culprits: TERT Promoter Mutation Screening of Minimally Invasive Follicular and Oncocytic Thyroid Carcinoma in Clinical Practice
Hellgren LS; Stenman A; Jatta K; Condello V; Larsson C; Zedenius J; Juhlin CC
Article: ENDOCRINE-RELATED CANCER. 2024;31(9):e230061
Genetic variants and down-regulation of CACNA1H in pheochromocytoma.
Svahn F; Solhusløkk Höse K; Stenman A; Liu Y; Calissendorff J; Tham E; Végvári Á; Zubarev RA; Wang N; Korah R; Carling T; Zedenius J; Bränström R; Juhlin CC; Larsson C
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2024;:dgae589
BRAF-induced EHF Expression Affects TERT in Aggressive Papillary Thyroid Cancer
Xu Y; Gao J; Wang N; Zedenius J; Nilsson I-L; Lui W-O; Xu D; Juhlin CC; Larsson C; Mu N
Article: VIRCHOWS ARCHIV. 2024;485(1):105-114
Atrophic changes in thyroid tumors are strong indicators of underlying DICER1 mutations: a bi-institutional genotype-phenotype correlation study
Condello V; Roberts JW; Stenman A; Larsson C; Viswanathan K; Juhlin CC
Article: ESMO OPEN. 2024;9(7):103617
Comprehensive genomic analysis of adrenocortical carcinoma reveals genetic profiles associated with patient survival
Sun-Zhang A; Juhlin CC; Carling T; Scholl U; Schott M; Larsson C; Bajalica-Lagercrantz S
Article: EXPERIMENTAL CELL RESEARCH. 2023;433(2):113858
Ca2+-activated K plus channels modulate membrane potential in the human parathyroid cell: Possible role in exocytosis
Branstrom R; Vukojevic V; Lu M; Shabo I; Mun H-C; Conigrave AD; Farnebo L-O; Larsson C
Article: JOURNAL OF HISTOCHEMISTRY AND CYTOCHEMISTRY. 2023;71(8):451-458
5hmC Immunohistochemistry: A Predictor of TERT Promoter Mutational Status in Follicular Thyroid Carcinoma?
Hysek M; Hellgren SLL; Condello V; Xu Y; Larsson C; Zedenius J; Juhlin CC
Article: DIAGNOSTIC CYTOPATHOLOGY. 2023;51(6):331-340
Digital droplet PCR TERT promoter mutational screening in fine needle aspiration cytology of thyroid lesions: A highly specific technique for pre-operative identification of high-risk cases
Hysek M; Hellgren LS; Stenman A; Darai-Ramqvist E; Ljung E; Schliemann I; Condello V; Larsson C; Zedenius J; Jatta K; Juhlin CC
Article: ENDOCRINE PATHOLOGY. 2023;34(1):129-141
TOP2A Expression in Pheochromocytoma and Abdominal Paraganglioma: a Marker of Poor Clinical Outcome?
Hose KS; Stenman A; Svahn F; Larsson C; Juhlin CC
Article: SCIENTIFIC REPORTS. 2023;13(1):1070
Thyroglobulin expression, Ki-67 index, and lymph node ratio in the prognostic assessment of papillary thyroid cancer
Lindfors H; Karlsen M; Karlton E; Zedenius J; Larsson C; Ihre Lundgren C; Juhlin CC; Shabo I
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2022;61(5):140
Altered expression of the IGF2-H19 locus and mitochondrial respiratory complexes in adrenocortical carcinoma
Scicluna P; Caramuta S; Kjellin H; Xu C; Froebom R; Akhtar M; Gao J; Shi H; Kjellman M; Almgren M; Hoog A; Zedenius J; Ekstroem TJ; Braenstroem R; Lui W-O; Larsson C
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2022;107(10):2811-2821
Presentation, Management, and Outcomes of Urinary Bladder Paraganglioma: Results From a Multicenter Study
Yu K; Ebbehoj AL; Obeid H; Vaidya A; Else T; Wachtel H; Main AM; Sondergaard E; Christensen LL; Juhlin CC; Calissendorff J; Cohen DL; Bennett B; Andersen MS; Larsson C; Almeida MQ; Fishbein L; Boorjian SA; Young WFJ; Bancos I
Article: NATURE METABOLISM. 2022;4(6):739-758
Impaired oxygen-sensitive regulation of mitochondrial biogenesis within the von Hippel-Lindau syndrome
Li S; Li W; Yuan J; Bullova P; Wu J; Zhang X; Liu Y; Plescher M; Rodriguez J; Bedoya-Reina OC; Jannig PR; Valente-Silva P; Yu M; Henriksson MA; Zubarev RA; Smed-Sorensen A; Suzuki CK; Ruas JL; Holmberg J; Larsson C; Christofer Juhlin C; von Kriegsheim A; Cao Y; Schlisio S
Article: ENDOCRINE PATHOLOGY. 2022;33(2):231-242
Prognostic Utility of the Ki-67 Labeling Index in Follicular Thyroid Tumors: a 20-Year Experience from a Tertiary Thyroid Center
Hellgren LS; Stenman A; Paulsson JO; Hoog A; Larsson C; Zedenius J; Juhlin CC
Article: BIOMEDICINE & PHARMACOTHERAPY. 2022;149:112796
Synergistic effects of telomerase reverse transcriptase and regulator of telomere elongation helicase 1 on aggressiveness and outcomes in adrenocortical carcinoma
Yuan H; Wu Y; Wang J; Qin X; Huang Y; Yan L; Fana Y; Zedenius J; Juhlin CC; Larsson C; Lui W-O; Xu D
Article: BIOMEDICINES. 2022;10(5):1004
Whole-Exome Sequencing of Germline Variants in Non-BRCA Families with Hereditary Breast Cancer
Liu Y; Helgadottir HT; Kharaziha P; Choi J; Lopez-Giraldez F; Mane SM; Hoiom V; Juhlin CC; Larsson C; Bajalica-Lagercrantz S
Article: CANCERS. 2022;14(6):1385
Downregulation and Hypermethylation of GABPB1 Is Associated with Aggressive Thyroid Cancer Features
Xing X; Mu N; Yuan X; Wang N; Juhlin CC; Straat K; Larsson C; Neo SY; Xu D
Article: ISCIENCE. 2021;24(11):103264
Merkel cell polyomavirus T-antigens regulate DICER1 mRNA stability and translation through HSC70
Gao J; Shi H; Juhlin CC; Larsson C; Lui W-O
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(19):10600
Imatinib Regulates miR-483-3p and Mitochondrial Respiratory Complexes in Gastrointestinal Stromal Tumors
Huang W-K; Shi H; Akcakaya P; Zeljic K; Gangaev A; Caramuta S; Yeh C-N; Branstrom R; Larsson C; Lui W-O
Article: NATURE COMMUNICATIONS. 2021;12(1):5309
Single-nuclei transcriptomes from human adrenal gland reveal distinct cellular identities of low and high-risk neuroblastoma tumors
Bedoya-Reina OC; Li W; Arceo M; Plescher M; Bullova P; Pui H; Kaucka M; Kharchenko P; Martinsson T; Holmberg J; Adameyko I; Deng Q; Larsson C; Juhlin CC; Kogner P; Schlisio S
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(12):6345
Association between Predicted Effects of TP53 Missense Variants on Protein Conformation and Their Phenotypic Presentation as Li-Fraumeni Syndrome or Hereditary Breast Cancer
Liu Y; Axell O; van Leeuwen T; Konrat R; Kharaziha P; Larsson C; Wright APH; Bajalica-Lagercrantz S
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2021;557:14-19
Direct interaction of the ATP-sensitive K⁺ channel by the tyrosine kinase inhibitors imatinib, sunitinib and nilotinib
Frobom R; Berglund E; Aspinwall CA; Lui W-O; Nilsson I-L; Larsson C; Branstrom R
Article: JOURNAL OF CLINICAL PATHOLOGY. 2021;75(10):jclinpath-2021-207631-662
Nuclear-specific accumulation of telomerase reverse transcriptase (TERT) mRNA in TERT promoter mutated follicular thyroid tumours visualised by in situ hybridisation: a possible clinical screening tool?
Hellgren LS; Olsson A; Kaufeldt A; Paulsson JO; Hysek M; Stenman A; Zedenius J; Larsson C; Hoog A; Juhlin CC
Article: NUCLEIC ACIDS RESEARCH (NAR). 2021;49(5):2509-2521
Aberrant splicing in neuroblastoma generates RNA-fusion transcripts and provides vulnerability to spliceosome inhibitors
Shi Y; Yuan J; Rraklli V; Maxymovitz E; Cipullo M; Liu M; Li S; Westerlund I; Bedoya-Reina OC; Bullova P; Rorbach J; Juhlin CC; Stenman A; Larsson C; Kogner P; O'Sullivan MJ; Schlisio S; Holmberg J
Article: JOURNAL OF MOLECULAR DIAGNOSTICS. 2021;23(2):212-222
Spatial Distribution Patterns of Clinically Relevant TERT Promoter Mutations in Follicular Thyroid Tumors of Uncertain Malignant Potential Advantages of the Digital Droplet PCR Technique
Hysek M; Jatta K; Hellgren LS; Stenman A; Larsson C; Zedenius J; Juhlin CC
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2020;21(21):E8072-8072
Activation of RAS Signalling is Associated with Altered Cell Adhesion in Phaeochromocytoma
Rossitti HM; Dutta RK; Larsson C; Ghayee HK; Soderkvist P; Gimm O
Article: CANCERS. 2020;12(8):E2133-2133
PLEKHS1 Over-Expression is Associated with Metastases and Poor Outcomes in Papillary Thyroid Carcinoma
Xing X; Mu N; Yuan X; Wang N; Juhlin CC; Straat K; Larsson C; Xu D
Article: CELLS. 2020;9(6):E1333-1333
Heterogeneity of Metabolic Vulnerability in Imatinib-Resistant Gastrointestinal Stromal Tumor
Huang W-K; Gao J; Chen Z; Shi H; Yuan J; Cui HL; Yeh C-N; Branstrom R; Larsson C; Li S; Lui W-O
Article: ENDOCRINE-RELATED CANCER. 2020;27(5):295-308
GABPA-dependent down-regulation of DICER1 in follicular thyroid tumours
Paulsson JO; Wang N; Gao J; Stenman A; Zedenius J; Mu N; Lui W-O; Larsson C; Juhlin CC
Article: INTERNATIONAL JOURNAL OF CANCER. 2020;146(6):1652-1666
Merkel cell polyomavirus oncoproteins induce microRNAs that suppress multiple autophagy genes
Kumar S; Xie H; Shi H; Gao J; Juhlin CC; Bjornhagen V; Hoog A; Lee L; Larsson C; Lui W-O
Article: EPIGENETICS. 2019;14(12):1224-1233
Telomerase activation in small intestinal neuroendocrine tumours is associated with aberrant TERT promoter methylation, but not hot-spot mutations
Fotouhi O; Ghaderi M; Wang N; Zedenius J; Kjellman M; Xu D; Juhlin CC; Larsson C
Article: ONCOGENE. 2019;38(43):6881-6897
Proteomics identifies neddylation as a potential therapy target in small intestinal neuroendocrine tumors
Fotouhi O; Kjellin H; Juhlin CC; Pan Y; Vesterlund M; Ghaderi M; Yousef A; Andersson-Sand H; Kharaziha P; Caramuta S; Kjellman M; Zedenius J; Larsson C; Orre LM
Article: CANCERS. 2019;11(10):E1443-1443
Clinical Routine TERT Promoter Mutational Screening of Follicular Thyroid Tumors of Uncertain Malignant Potential (FT-UMPs): A Useful Predictor of Metastatic Disease
Hysek M; Paulsson JO; Jatta K; Shabo I; Stenman A; Hoog A; Larsson C; Zedenius J; Juhlin CC
Article: ENDOCRINE PATHOLOGY. 2019;30(3):246-248
TERT Promoter Mutation Spatial Heterogeneity in a Metastatic Follicular Thyroid Carcinoma: Implications for Clinical Work-Up
Stenman A; Hysek M; Jatta K; Branstrom R; Darai-Ramqvist E; Paulsson JO; Wang N; Larsson C; Zedenius J; Juhlin CC
Article: CLINICAL GENETICS. 2019;96(3):216-225
Functional characterization of novel germline TP53 variants in Swedish families
Kharaziha P; Ceder S; Axell O; Krall M; Fotouhi O; Bohm S; Lain S; Borg A; Larsson C; Wiman KG; Tham E; Bajalica-Lagercrantz S
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2019;116(34):16997-17006
EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance
Li S; Rodriguez J; Li W; Bullova P; Fell SM; Surova O; Westerlund I; Topcic D; Bergsland M; Stenman A; Muhr J; Nister M; Holmberg J; Juhlin CC; Larsson C; von Kriegsheim A; Kaelin WGJ; Schlisio S
Article: JAMA NETWORK OPEN. 2019;2(8):e198898
Comparison of Pheochromocytoma-Specific Morbidity and Mortality Among Adults With Bilateral Pheochromocytomas Undergoing Total Adrenalectomy vs Cortical-Sparing Adrenalectomy
Neumann HPH; Tsoy U; Bancos I; Amodru V; Walz MK; Tirosh A; Kaur RJ; McKenzie T; Qi X; Bandgar T; Petrov R; Yukina MY; Roslyakova A; van der Horst-Schrivers ANA; Berends AMA; Hoff AO; Castroneves LA; Ferrara AM; Rizzati S; Mian C; Dvorakova S; Hasse-Lazar K; Kvachenyuk A; Peczkowska M; Loli P; Erenler F; Krauss T; Almeida MQ; Liu L; Zhu F; Recasens M; Wohllk N; Corssmit EPM; Shafigullina Z; Calissendorff J; Grozinsky-Glasberg S; Kunavisarut T; Schalin-Jantti C; Castinetti F; Vlcek P; Beltsevich D; Egorov VI; Schiavi F; Links TP; Lechan RM; Bausch B; Young WFJ; Eng C; Jaiswal SK; Zschiedrich S; Fragoso MCBV; Pereira MAA; Li M; Biarnes Costa J; Juhlin CC; Gross D; Violante AHD; Kocjan T; Ngeow J; Yoel U; Fraenkel M; Simsir IY; Ugurlu MU; Ziagaki A; Robles Diaz L; Kudlai IS; Gimm O; Scherbaum CR; Abebe-Campino G; Barbon G; Taschin E; Malinoc A; Khudiakova NV; Ivanov NV; Pfeifer M; Zovato S; Ploeckinger U; Makay O; Grineva E; Jarzab B; Januszewicz A; Shah N; Seufert J; Opocher G; Larsson C
Article: ANTICANCER RESEARCH. 2019;39(7):3433-3442
Biochemical Inhibition of DOG1/TMEM16A Achieves Antitumoral Effects in Human Gastrointestinal Stromal Tumor Cells In Vitro
Frobom R; Sellberg F; Xu C; Zhao A; Larsson C; Lui W-O; Nilsson I-L; Berglund E; Branstrom R
Article: AMERICAN JOURNAL OF SURGICAL PATHOLOGY. 2019;43(3):409-421
Molecular Profiling of Pheochromocytoma and Abdominal Paraganglioma Stratified by the PASS Algorithm Reveals Chromogranin B as Associated With Histologic Prediction of Malignant Behavior
Stenman A; Svahn F; Hojjat-Farsangi M; Zedenius J; Soderkvist P; Gimm O; Larsson C; Juhlin CC
Article: ONCOGENE. 2019;38(7):965-979
GABPA inhibits invasion/metastasis in papillary thyroid carcinoma by regulating DICER1 expression
Yuan X; Mu N; Wang N; Straat K; Sofiadis A; Guo Y; Stenman A; Li K; Cheng G; Zhang L; Kong F; Ekblad L; Wennerberg J; Nilsson I-L; Juhlin CC; Larsson C; Xu D
Article: CANCERS. 2018;10(11):E443-443
MiR-375 Regulation of LDHB Plays Distinct Roles in Polyomavirus-Positive and -Negative Merkel Cell Carcinoma
Kumar S; Xie H; Scicluna P; Lee L; Bjornhagen V; Hoog A; Larsson C; Lui W-O
Article: EXPERIMENTAL CELL RESEARCH. 2018;371(1):287-296
miR-125a-5p regulation increases phosphorylation of FAK that contributes to imatinib resistance in gastrointestinal stromal tumors
Huang W-K; Akcakaya P; Gangaev A; Lee L; Zeljic K; Hajeri P; Berglund E; Ghaderi M; Ahlen J; Branstrom R; Larsson C; Lui W-O
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2018;42(3):1675-1683
TERT promoter hypermethylation is associated with poor prognosis in adrenocortical carcinoma
Svahn F; Paulsson JO; Stenman A; Fotouhi O; Mu N; Murtha TD; Korah R; Carling T; Baeckdahl M; Wang N; Juhlin CC; Larsson C
Article: ENDOCRINE. 2018;61(2):293-302
High Ki-67 index in fine needle aspiration cytology of follicular thyroid tumors is associated with increased risk of carcinoma
Mu N; Juhlin CC; Tani E; Sofiadis A; Reihner E; Zedenius J; Larsson C; Nilsson I-L
Article: WORLD JOURNAL OF SURGERY. 2018;42(8):2512-2521
Wide Surgical Margin Improves the Outcome for Patients with Gastrointestinal Stromal Tumors (GISTs)
Ahlen J; Karlsson F; Wejde J; Nilsson I-L; Larsson C; Branstrom R
Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2018;470:84-95
Molecular profiles of oxyphilic and chief cell parathyroid adenoma
Lu M; Kjellin H; Fotouhi O; Lee L; Nilsson I-L; Haglund F; Hoog A; Lehtio J; Larsson C
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2018;103(7):2640-2650
Comprehensive Genetic Analysis of Follicular Thyroid Carcinoma Predicts Prognosis Independent of Histology
Nicolson NG; Murtha TD; Dong W; Paulsson JO; Choi J; Barbieri AL; Brown TC; Kunstman JW; Larsson C; Prasad ML; Korah R; Lifton RP; Juhlin CC; Carling T
Article: ENDOCRINE-RELATED CANCER. 2018;25(7):723-733
TERT aberrancies: a screening tool for malignancy in follicular thyroid tumours
Paulsson JO; Mu N; Shabo I; Wang N; Zedenius J; Larsson C; Juhlin CC
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2018;52(4):1189-1197
LRIG1 negatively regulates RET mutants and is downregulated in thyroid cancer
Lindquist D; Alsina FC; Herdenberg C; Larsson C; Hoeppener J; Wang N; Paratcha G; Tarjan M; Tot T; Henriksson R; Hedman H
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2018;52(1):55-66
MicroRNA expression profiles in non-epithelial ovarian tumors
Chang RK; Li X; Mu N; Hrydziuszko O; Garcia-Majano B; Larson C; Lui W-O
Article: PATHOBIOLOGY. 2018;85(4):211-219
Proteomic Profiling of Diffuse Large B-Cell Lymphomas
Kwiecinska A; Porwit A; Souchelnytskyi N; Kaufeldt A; Larsson C; Bajalica-Lagercrantz S; Souchelnytskyi S
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2017;177(6):445-453
Inflammatory infiltrates in parathyroid tumors
Haglund F; Hallstrom BM; Nilsson I-L; Hoog A; Juhlin CC; Larsson C
Article: ONCOLOGIST. 2017;22(10):1178-1188
TERT Promoter Hypermethylation in Gastrointestinal Cancer: A Potential Stool Biomarker
Liu L; Liu C; Fotouhi O; Fan Y; Wang K; Xia C; Shi B; Zhang G; Wang K; Kong F; Larsson C; Hu S; Xu D
Article: JAMA ONCOLOGY. 2017;3(9):1204-1212
Clinical Characterization of the Pheochromocytoma and Paraganglioma Susceptibility Genes SDHA, TMEM127, MAX, and SDHAF2 for Gene-Informed Prevention
Bausch B; Schiavi F; Ni Y; Welander J; Patocs A; Ngeow J; Wellner U; Malinoc A; Taschin E; Barbon G; Lanza V; Soederkvist P; Stenman A; Larsson C; Svahn F; Chen J-L; Marquard J; Fraenkel M; Walter MA; Peczkowska M; Prejbisz A; Jarzab B; Hasse-Lazar K; Petersenn S; Moeller LC; Meyer A; Reisch N; Trupka A; Brase C; Galiano M; Preuss SF; Kwok P; Lendvai N; Berisha G; Makay O; Boedeker CC; Weryha G; Racz K; Januszewicz A; Walz MK; Gimm O; Opocher G; Eng C; Neumann HPH
Article: CELL DEATH AND DISEASE. 2017;8(5):e2759
Loss of miR-514a-3p regulation of PEG3 activates the NF-kappa B pathway in human testicular germ cell tumors
Ozata DM; Li X; Lee L; Liu J; Warsito D; Hajeri P; Hultman I; Fotouhi O; Marklund S; Ahrlund-Richter L; Juhlin CC; Larsson C; Lui W-O
Article: ONCOLOGY LETTERS. 2017;13(5):3586-3598
Evaluation of microRNA-205 expression as a potential triage marker for patients with low-grade squamous intraepithelial lesions
Xie H; Norman I; Hjerpe A; Vladic T; Larsson C; Lui W-O; Ostensson E; Andersson S
Article: BMC CANCER. 2017;17(1):164
A novel FOXO1-mediated dedifferentiation blocking role for DKK3 in adrenocortical carcinogenesis
Cheng JY; Brown TC; Murtha TD; Stenman A; Juhlin CC; Larsson C; Healy JM; Prasad ML; Knoefel WT; Krieg A; Scholl UI; Korah R; Carling T
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2017;50(2):356-364
miR-223-3p regulates cell growth and apoptosis via FBXW7 suggesting an oncogenic role in human testicular germ cell tumors
Liu J; Shi H; Li X; Chen G; Larsson C; Lui W-O
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2016;101(10):3616-3627
Proteomics Suggests a Role for APC-Survivin in Response to Somatostatin Analog Treatment of Neuroendocrine Tumors
Fotouhi O; Kjellin H; Larsson C; Hashemi J; Barriuso J; Juhlin CC; Lu M; Hoog A; Pastrian LG; Lamarca A; Heredia Soto V; Zedenius J; Mendiola M; Lehtio J; Kjellman M
Article: ENDOCRINE. 2016;53(2):505-511
Minimally invasive follicular thyroid carcinomas: prognostic factors
Stenson G; Nilsson I-L; Mu N; Larsson C; Lundgren CI; Juhlin CC; Hoog A; Zedenius J
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2016;174(5):583-590
Diffuse PTH expression in parathyroid tumors argues against important functional tumor subclones
Haglund F; Juhlin CC; Kiss NB; Larsson C; Nilsson I-L; Hoog A
Article: GENES CHROMOSOMES AND CANCER. 2016;55(5):452-459
HRAS mutation prevalence and associated expression patterns in pheochromocytoma
Stenman A; Welander J; Gustavsson I; Brunaud L; Backdahl M; Soderkvist P; Gimm O; Juhlin CC; Larsson C
Article: ONCOTARGET. 2016;7(16):21332-21346
Genetic and epigenetic background and protein expression profiles in relation to telomerase activation in medullary thyroid carcinoma
Wang N; Kjellin H; Sofiadis A; Fotouhi O; Juhlin CC; Backdahl M; Zedenius J; Xu D; Lehtio J; Larsson C
Article: PLOS ONE. 2016;11(9):e0162379
Human Cytochrome P450 2W1 Is Not Expressed in Adrenal Cortex and Is Only Rarely Expressed in Adrenocortical Carcinomas
Nole P; Duijndam B; Stenman A; Juhlin CC; Kozyra M; Larsson C; Ingelman-Sundberg M; Johansson I
Article: EXPERIMENTAL CELL RESEARCH. 2015;336(1):158-170
Secretome protein signature of human gastrointestinal stromal tumor cells
Berglund E; Dare E; Branca RMM; Akcakaya P; Frobom R; Berggren P-O; Lui W-O; Larsson C; Zedenius J; Orre L; Lehtio J; Kim J; Branstrom R
Article: HUMAN MOLECULAR GENETICS. 2015;24(8):2318-2329
Characterization of the mutational landscape of anaplastic thyroid cancer via whole-exome sequencing
Kunstman JW; Juhlin CC; Goh G; Brown TC; Stenman A; Healy JM; Rubinstein JC; Choi M; Kiss N; Nelson-Williams C; Mane S; Rimm DL; Prasad ML; Hoog A; Zedenius J; Larsson C; Korah R; Lifton RP; Carling T
Article: ENDOCRINE CONNECTIONS. 2015;4(1):76-85
Tumour nuclear oestrogen receptor beta 1 correlates inversely with parathyroid tumour weight
Haglund F; Rosin G; Nilsson I-L; Juhlin CC; Pernow Y; Norenstedt S; Dinets A; Larsson C; Hartman J; Hoog A
Article: INTERNATIONAL JOURNAL OF CANCER. 2015;136(5):E230-E241
Novel functions and targets of miR-944 in human cervical cancer cells
Xie H; Lee L; Scicluna P; Kavak E; Larsson C; Sandberg R; Lui W-O
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2015;100(3):E493-E502
Whole-Exome Sequencing Characterizes the Landscape of Somatic Mutations and Copy Number Alterations in Adrenocortical Carcinoma
Juhlin CC; Goh G; Healy JM; Fonseca AL; Scholl UI; Stenman A; Kunstman JW; Brown TC; Overton JD; Mane SM; Nelson-Williams C; Backdahl M; Suttorp A-C; Haase M; Choi M; Schlessinger J; Rimm DL; Hoog A; Prasad ML; Korah R; Larsson C; Lifton RP; Carling T
Article: PLOS ONE. 2015;10(5):e0126472
Differential Protein Expression Profiles of Cyst Fluid from Papillary Thyroid Carcinoma and Benign Thyroid Lesions
Dinets A; Pernemalm M; Kjellin H; Sviatoha V; Sofiadis A; Juhlin CC; Zedenius J; Larsson C; Lehtio J; Hoog A
Article: BRITISH JOURNAL OF CANCER. 2014;111(11):2091-2102
microRNA expression signatures of gastrointestinal stromal tumours: associations with imatinib resistance and patient outcome
Akcakaya P; Caramuta S; Ahlen J; Ghaderi M; Berglund E; Ostman A; Branstrom R; Larsson C; Lui W-O
Article: CLINICAL CANCER RESEARCH. 2014;20(22):5733-5744
Human Anaplastic Thyroid Carcinoma Cells Are Sensitive to NK Cell-Mediated Lysis via ULBP2/5/6 and Chemoattract NK Cells
Wennerberg E; Pfefferle A; Ekblad L; Yoshimoto Y; Kremer V; Kaminskyy VO; Juhlin CC; Hoog A; Bodin I; Svjatoha V; Larsson C; Zedenius J; Wennerberg J; Lundqvist A
Article: ONCOTARGET. 2014;5(20):10048-10057
TERT promoter mutations and gene amplification: Promoting TERT expression in Merkel cell carcinoma
Xie H; Liu T; Wang N; Bjornhagen V; Hoog A; Larsson C; Lui W-O; Xu D
Article: ONCOGENE. 2014;33(42):4978-4984
The age- and shorter telomere-dependent TERT promoter mutation in follicular thyroid cell-derived carcinomas
Liu T; Wang N; Cao J; Sofiadis A; Dinets A; Zedenius J; Larsson C; Xu D
Article: CANCER. 2014;120(19):2965-2979
TERT Promoter Mutation as an Early Genetic Event Activating Telomerase in Follicular Thyroid Adenoma (FTA) and Atypical FTA
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Amplification of 2p as a Genomic Marker for Transformation in Lymphoma
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Article: EXPERIMENTAL CELL RESEARCH. 2014;326(2):315-325
Functional role of the Ca²⁺-activated Cl^- channel DOG1/TMEM16A in gastrointestinal stromal tumor cells
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Telomerase-Dependent and Independent Telomere Maintenance and its Clinical Implications in Medullary Thyroid Carcinoma
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Article: EPIGENETICS. 2014;9(7):987-997
Global hypomethylation and promoter methylation in small intestinal neuroendocrine tumors An in vivo and in vitro study
Fotouhi O; Fahmideh MA; Kjellman M; Sulaiman L; Hoog A; Zedenius J; Hashemi J; Larsson C
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Rare Germline Mutations Identified by Targeted Next-Generation Sequencing of Susceptibility Genes in Pheochromocytoma and Paraganglioma
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Article: ENDOCRINE-RELATED CANCER. 2014;21(3):427-434
The activating TERT promoter mutation C228T is recurrent in subsets of adrenal tumors
Liu T; Brown TC; Juhlin CC; Andreasson A; Wang N; Backdahl M; Healy JM; Prasad ML; Korah R; Carling T; Xu D; Larsson C
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Frequent EPAS1/HIF2α exons 9 and 12 mutations in non-familial pheochromocytoma
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Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2014;170(4):583-591
MicroRNA expression patterns associated with hyperfunctioning and non-hyperfunctioning phenotypes in adrenocortical adenomas
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Intracellular concentration of the tyrosine kinase inhibitor imatinib in gastrointestinal stromal tumor cells
Berglund E; Ubhayasekera SJKA; Karlsson F; Akcakaya P; Aluthgedara W; Ahlen J; Frobom R; Nilsson I-L; Lui W-O; Larsson C; Zedenius J; Bergquist J; Branstrom R
Article: WORLD JOURNAL OF SURGERY. 2014;38(3):724-732
Role of SDHAF2 and SDHD in von Hippel-Lindau Associated Pheochromocytomas
Kugelberg J; Welander J; Schiavi F; Fassina A; Backdahl M; Larsson C; Opocher G; Soderkvist P; Dahia PL; Neumann HPH; Gimm O
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2014;134(2):507-517
MicroRNA Expression Patterns Related to Merkel Cell Polyomavirus Infection in Human Merkel Cell Carcinoma
Xie H; Lee L; Caramuta S; Hoog A; Browaldh N; Bjornhagen V; Larsson C; Lui W-O
Article: PLOS ONE. 2014;9(11):e111125
Expression of the p53 Target Wig-1 Is Associated with HPV Status and Patient Survival in Cervical Carcinoma
Xu L-D; Muller S; Thoppe SR; Hellborg F; Kanter L; Lerner M; Zheng B; Lagercrantz SB; Grander D; Wallin KL; Wiman KG; Larsson C; Andersson S
Article: EPIGENETICS. 2013;8(12):1347-1354
The VHL gene is epigenetically inactivated in pheochromocytomas and abdominal paragangliomas
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Copy number alterations in small intestinal neuroendocrine tumors determined by array comparative genomic hybridization
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Role of microRNAs and microRNA machinery in the pathogenesis of diffuse large B-cell lymphoma
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Inhibition of Parathyroid Hormone Secretion by Caffeine in Human Parathyroid Cells
Lu M; Farnebo L-O; Branstrom R; Larsson C
Article: ENDOCRINE-RELATED CANCER. 2013;20(4):551-564
Clinical and functional impact of TARBP2 over-expression in adrenocortical carcinoma
Caramuta S; Lee L; Ozata DM; Akcakaya P; Xie H; Hoog A; Zedenius J; Backdahl M; Larsson C; Lui W-O
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Global and gene-specific promoter methylation analysis in primary hyperparathyroidism
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Article: EXPERIMENTAL CELL RESEARCH. 2013;319(8):1229-1238
Evidence for Ca²⁺-regulated ATP release in gastrointestinal stromal tumors
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Epigenetic Aspects on Therapy Development for Gastroenteropancreatic Neuroendocrine Tumors
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Article: JOURNAL OF SURGICAL ONCOLOGY. 2012;106(8):981-986
Anaplastic carcinoma of the thyroid gland: Treatment and outcome over 13 years at one institution
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Article: HUMAN MOLECULAR GENETICS. 2012;21(26):5406-5416
Integrative genomics reveals frequent somatic NF1 mutations in sporadic pheochromocytomas
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Evidence of a Functional Estrogen Receptor in Parathyroid Adenomas
Haglund F; Ma R; Huss M; Sulaiman L; Lu M; Nilsson I-L; Hoog A; Juhlin CC; Hartman J; Larsson C
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Cell type and context-specific function of PLAG1 for IGF2 P3 promoter activity
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Article: BMC MEDICAL GENETICS. 2012;13:83
Quantitative global and gene-specific promoter methylation in relation to biological properties of neuroblastomas
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Article: FAMILIAL CANCER. 2012;11(3):355-362
Molecular characterization of parathyroid tumors from two patients with hereditary colorectal cancer syndromes
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Clinical, genetic, and immunohistochemical characterization of 70 Ukrainian adult cases with post-Chornobyl papillary thyroid carcinoma
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Article: ENDOCRINE-RELATED CANCER. 2012;19(3):389-407
Genetic characterization of large parathyroid adenomas
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Proteomic profiling of follicular and papillary thyroid tumors
Sofiadis A; Becker S; Hellman U; Hultin-Rosenberg L; Dinets A; Hulchiy M; Zedenius J; Wallin G; Foukakis T; Hoog A; Auer G; Lehtio J; Larsson C
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miR-205 Expression Promotes Cell Proliferation and Migration of Human Cervical Cancer Cells
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Genome-Wide and Locus Specific Alterations in CDC73/HRPT2-Mutated Parathyroid Tumors
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Prolactin Receptor in Primary Hyperparathyroidism - Expression, Functionality and Clinical Correlations
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Epigenetic Regulation of Glucose Transporter 4 by Estrogen Receptor β
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Article: ENDOCRINE-RELATED CANCER. 2011;18(6):643-655
The role of microRNA deregulation in the pathogenesis of adrenocortical carcinoma
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Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2011;411(1):208-212
Enhanced effects by 4-phenylbutyrate in combination with RTK inhibitors on proliferation in brain tumor cell models
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Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2011;411(1):156-161
The pattern of gene expression and gene dose profiles of 6-Mercaptopurine- and 6-Thioguanine-resistant human leukemia cells
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Absence of nucleolar parafibromin immunoreactivity in subsets of parathyroid malignant tumours
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Molecular Characterization of Acquired Tolerance of Tumor Cells to Picropodophyllin (PPP)
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Calmodulin and calmodulin-dependent protein kinase II inhibit hormone secretion in human parathyroid adenoma
Lu M; Berglund E; Larsson C; Hoog A; Farnebo L-O; Branstrom R
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Proteomic Study of Thyroid Tumors Reveals Frequent Up-Regulation of the Ca²⁺-Binding Protein S100A6 in Papillary Thyroid Carcinoma
Sofiadis A; Dinets A; Orre LM; Branca RM; Juhlin CC; Foukakis T; Wallin G; Hoog A; Hulchiy M; Zedenius J; Larsson C; Lehtio J
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Suppression of RIZ in biologically unfavourable neuroblastomas
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Parafibromin and APC as Screening Markers for Malignant Potential in Atypical Parathyroid Adenomas
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Article: ENDOCRINE-RELATED CANCER. 2010;17(3):561-579
Recurrent genomic alterations in benign and malignant pheochromocytomas and paragangliomas revealed by whole-genome array comparative genomic hybridization analysis
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MicroRNA Expression Profiles Associated with Mutational Status and Survival in Malignant Melanoma
Caramuta S; Egyhazi S; Rodolfo M; Witten D; Hansson J; Larsson C; Lui W-O
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Expression and association of TRPC subtypes with Orai1 and STIM1 in human parathyroid
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Frequent Promoter Hypermethylation of the APC and RASSF1A Tumour Suppressors in Parathyroid Tumours
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Article: AMERICAN JOURNAL OF PATHOLOGY. 2009;175(5):1831-1847
Detection of Genomic Amplification of the Human Telomerase Gene TERC, a Potential Marker for Triage of Women with HPV-Positive, Abnormal Pap Smears
Andersson S; Sowjanya P; Wangsa D; Hjerpe A; Johansson B; Auer G; Gravitt PE; Larsson C; Wallin K-L; Ried T; Heselmeyer-Haddad K
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2009;85(5):617-627
Autosomal-Dominant Retinitis Pigmentosa Caused by a Mutation in SNRNP200, a Gene Required for Unwinding of U4/U6 snRNAs
Zhao C; Bellur DL; Lu S; Zhao F; Grassi MA; Bowne SJ; Sullivan LS; Daiger SP; Chen LJ; Pang CP; Zhao K; Staley JP; Larsson C
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2009;161(1):141-152
Transcriptional profiling enables molecular classification of adrenocortical tumours
Laurell C; Velazquez-Fernandez D; Lindsten K; Juhlin C; Enberg U; Geli J; Hoog A; Kjellman M; Lundeberg J; Hamberger B; Larsson C; Nilsson P; Backdahl M
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Diagnostic and prognostic potential of MIB-1 proliferation index in thyroid fine needle aspiration biopsy
Sofiadis A; Tani E; Foukakis T; Kjellman P; Skoog L; Hoog A; Wallin G; Zedenius J; Larsson C
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Mutation analysis of MEN1, HRPT2, CASR, CDKN1B, and AIP genes in primary hyperparathyroidism patients with features of genetic predisposition
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Article: BIOCHEMICAL PHARMACOLOGY. 2009;77(8):1410-1417
Gene expression profiling of leukemia T-cells resistant to methotrexate and 7-hydroxymethotrexate reveals alterations that preserve intracellular levels of folate and nucleotide biosynthesis
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Ror1, a cell surface receptor tyrosine kinase is expressed in chronic lymphocytic leukemia and may serve as a putative target for therapy
DaneshManesh AH; Mikaelsson E; Jeddi-Tehrani M; Bayat AA; Ghods R; Ostadkarampour M; Akhondi M; Lagercrantz S; Larsson C; Osterborg A; Shokri F; Mellstedt H; Rabbani H
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CREB3L2-PPARγ fusion mutation identifies a thyroid signaling pathway regulated by intramembrane proteolysis
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Array-CGH identifies cyclin D1 and UBCH10 amplicons in anaplastic thyroid carcinoma
Lee J-J; Au AYM; Foukakis T; Barbaro M; Kiss N; Clifton-Bligh R; Staaf J; Borg A; Delbridge L; Robinson BG; Wallin G; Hoog A; Larsson C
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Assessment of NORE1A as a putative tumor suppressor in human neuroblastoma
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Heterogeneous expression of SNARE proteins SNAP-23, SNAP-25, syntaxin1 and VAMP in human parathyroid tissue
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Methylation of the p16^INK4A promoter is associated with malignant behavior in abdominal extra-adrenal paragangliomas but not pheochromocytomas
Kiss NB; Geli J; Lundberg F; Avci C; Velazquez-Fernandez D; Hashemi J; Weber G; Hoog A; Ekstrom TJ; Backdahl M; Larsson C
Article: CLINICAL CANCER RESEARCH. 2008;14(9):2551-2559
Global and regional CpG methylation in pheochromocytomas and abdominal paragangliomas:: Association to malignant behavior
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Article: JOURNAL OF PATHOLOGY. 2008;215(1):87-96
Frizzled-1 is down-regulated in follicular thyroid tumours and modulates growth and invasiveness
Ulivieri A; Lavra L; Dominici R; Giacomelli L; Brunetti E; Sciacca L; Trovato M; Barresi G; Foukakis T; Jia-Jing L; Larsson C; Bartolazzi A; Sciacchitano S
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Familial non-syndromic cleft lip and palate -: analysis of the IRF6 gene and clinical phenotypes
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Novel and recurrent KIF21A mutations in congenital fibrosis of the extraocular muscles type 1 and 3
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Characterization of 6q deletions in mature B cell lymphomas and childhood acute lymphoblastic leukemia
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Detailed assessment of copy number alterations revealing homozygous deletions in 1p and 13q in mantle cell lymphoma
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Two Chinese families with pulverulent congenital cataracts and ΔG91 CRYBA1 mutations
Lu S; Zhao C; Jiao H; Kere J; Tang X; Zhao F; Zhang X; Zhao K; Larsson C
Article: ENDOCRINE-RELATED CANCER. 2007;14(2):501-512
Parafibromin immunoreactivity:: its use as an additional diagnostic marker for parathyroid tumor classification
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A PCR-based expression signature of malignancy in follicular thyroid tumors
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Molecular cytogenetic profiles of novel and established human anaplastic thyroid carcinoma models
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Article: ENDOCRINE-RELATED CANCER. 2007;14(1):125-134
The Ras effectors NORE1A and RASSF1A are frequently inactivated in pheochromocytoma and abdominal paraganglioma
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Genomic imbalances during transformation from follicular lymphoma to diffuse large B-cell lymphoma
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Pre-fractionation of archival frozen turnours for proteomics applications
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Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2006;29(5):1173-1182
A dog pedigree with familial medullary thyroid cancer
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Article: BRITISH JOURNAL OF CANCER. 2006;95(3):331-338
Frequent gain of the human telomerase gene TERC at 3q26 in cervical adenocarcinomas
Andersson S; Wallin K-L; Hellstroem A-C; Morrison LE; Hjerpe A; Auer G; Ried T; Larsson C; Heselmeyer-Haddad K
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LUMA (LUminometric Methylation Assay) -: A high throughput method to the analysis of genomic DNA methylation
Karimi M; Johansson S; Stach D; Corcoran M; Grander D; Schalling M; Bakalkin G; Lyko F; Larsson C; Ekstrom TJ
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A novel locus (RP33) for autosomal dominant retinitis pigmentosa mapping to chromosomal region 2cen-q12.1
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A 10-year-old girl with bifocal synovial sarcoma
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Loss of parafibromin expression in a subset of parathyroid adenomas
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The insulin-like growth factor-1 receptor inhibitor PPP produces only very limitedresistance in tumor cells exposed to long-term selection
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Article: EUROPEAN JOURNAL OF SURGICAL ONCOLOGY. 2006;32(3):345-352
Predictors of outcome in patients with papillary thyroid carcinoma
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Detailed assessment of chromosome 22 aberrations in sporadic pheochromocytoma using array-CGH
Jarbo C; Buckley PG; Piotrowski A; Mantripragada KK; Benetkiewicz M; de Ståhl TD; Langford CF; Gregory SG; Dralle H; Gimm O; Bäckdahl M; Geli J; Larsson C; Westin G; Aring; kerström G; Dumanski JP
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The Ras effector NORE1A is suppressed in follicular thyroid carcinomas with a PAX8-PPARγ fusion
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Article: INTERNATIONAL JOURNAL OF RADIATION BIOLOGY. 2006;82(2):87-96
Evaluation of spectral karyotyping (SKY) in biodosimetry for the triage situation following gamma irradiation
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Article: PROSTATE. 2006;66(2):157-172
Cytogenetic and expression profiles associated with transformation to androgen-resistant prostate cancer
Pang ST; Weng WH; Flores-Morales A; Johansson B; Pourian MR; Nilsson P; Pousette Å; Larsson C; Norstedt G
Article: ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY. 2006;101(2):214-220
Dental findings in a family with hyperparathyroidism-jaw tumor syndrome and a novel HRPT2 gene mutation
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Article: TUMOR BIOLOGY. 2006;27(4):211-220
Molecular markers for discrimination of benign and malignant follicular thyroid tumors
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Article: INTERNAL MEDICINE. 2006;45(2):81-86
Multiple endocrine neoplasia type I and Cushing's syndrome due to an aggressive ACTH producing thymic carcinoid
Takagi J; Otake K; Morishita M; Kato H; Nakao N; Yoshikawa K; Ikeda H; Hirooka Y; Hattori Y; Larsson C; Nogimori T
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2005;13(12):1261-1267
Novel and de novo mutations of the IRF6 gene detected in patients with Van der Woude or popliteal pterygium syndrome
Peyrard-Janvid M; Pegelow M; Koillinen H; Larsson C; Fransson I; Rautio J; Hukki J; Larson O; Karsten ALA; Kere J
Article: EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY AND DIABETES. 2005;113(9):516-521
Lack of mutations in the TSHr and Gsα genes in TSHr antibody negative Graves' disease
Elgadi A; Frisk T; Larsson C; Wallin G; Höög A; Zedenius J; Norgren S
Article: CLINICAL CANCER RESEARCH. 2005;11(17):6198-6204
Prognostic impact of immunohistochemical expression of ezrin in highly malignant soft tissue sarcomas
Weng WH; Åhlén J; Åström K; Lui WO; Larsson C
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2005;13(8):970-977
Loss of ZDHHC15 expression in a woman with a balanced translocation t(X;15)(q13.3;cen) and severe mental retardation
Mansouri MR; Marklund L; Gustavsson P; Davey E; Carlsson B; Larsson C; White I; Gustavson KH; Dahl N
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2005;26(5):1385-1391
Deletions and altered expression of the RIZ1 tumour suppressor gene in 1p36 in pheochromocytomas and abdominal paragangliomas
Geli J; Nord B; Frisk T; Elder EE; Ekström TJ; Carling T; Bäckdahl M; Larsson C
Article: JOURNAL OF SURGICAL ONCOLOGY. 2005;89(3):193-201
Pheochromocytoma and functional paraganglioma syndrome: No longer the 10% tumor
Elder EE; Elder G; Larsson C
Article: ANTICANCER RESEARCH. 2005;25(2A):683-691
Immunophenotypic and molecular cytogenetic features of the cell line UP-LN1 established from a lymph node metastasis of a poorly-differentiated carcinoma
Chang CTR; Weng WH; Chou ASB; Chuang CK; Porwit-Mcdonald A; Pang ST; Larsson C; Liao SK
Article: MODERN PATHOLOGY. 2005;18(3):331-339
Mantle cell lymphomas with clonal immunoglobulin V_H3-21 gene rearrangements exhibit fewer genomic imbalances than mantle cell lymphomas utilizing other immunoglobulin V_H genes
Thelander EF; Walsh SH; Thorsélius M; Laurell A; Landgren O; Larsson C; Rosenquist R; Lagercrantz S
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2005;152(3):459-470
Distinction in gene expression profiles demonstrated in parathyroid adenomas by high-density oligoarray technology
Forsberg L; Björck E; Hashemi J; Zedenius J; Höög A; Farnebo LO; Reimers M; Larsson C
Article: ONCOGENE. 2005;24(8):1467-1476
Expression profiling reveals a distinct transcription signature in follicular thyroid carcinomas with a PAX8-PPARγ fusion oncogene
Lui WO; Foukakis T; Lidén J; Thoppe SR; Dwight T; Höög A; Zedenius J; Wallin G; Reimers M; Larsson C
Article: CLINICAL CANCER RESEARCH. 2005;11(1):206-216
Insulin-like growth factor type 1 receptor expression correlates to good prognosis in highly malignant soft tissue sarcoma
Åhlén J; Wejde J; Brosjö O; von Rosen A; Weng WH; Girnita L; Larsson O; Larsson C
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2005;26(1):141-149
Molecular cytogenetic characterization of primary cultures and established cell lines from non-medullary thyroid tumors
Foukakis T; Thoppe SR; Lagercrantz S; Dwight T; Weng WH; Svensson A; Höög A; Zedenius J; Wallin G; Lui WO; Larsson C
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2005;26(1):5-16
Loss of chromosome 13q is a frequently acquired event in genetic progression of soft tissue sarcomas in the abdominal cavity
Weng WH; Lerner M; Grander D; Åhlén J; Villablanca A; Pang ST; Wejde J; Lui WO; Larsson C
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2004;25(4):955-960
Molecular cytogenetic characterization shows higher genetic homogeneity in conventional renal cell carcinoma compared to other kidney cancers
Alimov A; Sundelin B; Bergerheim U; Pavlenko M; Pisa P; Zetterberg A; Larsson C; Lagercrantz S
Article: GENES CHROMOSOMES AND CANCER. 2004;41(2):133-144
Spontaneously immortalized human T lymphocytes develop gain of chromosomal region 2p13-24 as an early and common genetic event
Siwicki JK; Berglund M; Rygier J; Pienkowska-Grela B; Grygalewicz B; Degerman S; Golovleva I; Chrzanowska KH; Lagercrantz S; Blennow E; Roos G; Larsson C
Article: GENES CHROMOSOMES AND CANCER. 2004;40(4):285-297
DLEU2 encodes an antisense RNA for the putative bicistronic RFP2/LEU5 gene in humans and mouse
Corcoran MM; Hammarsund M; Zhu CY; Lerner M; Kapanadze B; Wilson B; Larsson C; Forsberg L; Ibbotson RE; Stefan E; Oscier DG; Grandér D; Sangfelt O
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2004;25(1):179-185
Loss of 14q31-q32.2 in renal cell carcinoma is associated with high malignancy grade and poor survival
Alimov A; Sundelin B; Wang NN; Larsson C; Bergerheim U
Article: CANCER GENETICS. 2004;150(1):27-32
Characterization of large chromosome markers in a malignant fibrous histiocytoma by spectral karyotyping, comparative genomic hybridization (CGH), and array CGH
Weng WH; Wejde J; Åhlén J; Pang ST; Lui WO; Larsson C
Article: JOURNAL OF MEDICAL GENETICS. 2004;41(3):e32-32
Germline and de novo mutations in the HRPT2 tumour suppressor gene in familial isolated hyperparathyroidism (FIHP) -: art. no. e32
Villablanca A; Calender A; Forsberg L; Höög A; Cheng JD; Petillo D; Bauters C; Kahnoski K; Ebeling T; Salmela P; Richardson AL; Delbridge L; Meyrier A; Proye C; Carpten JD; Teh BT; Robinson BG; Larsson C
Article: CYTOGENETIC AND GENOME RESEARCH. 2004;106(1):28-32
Analysis of the cytogenetic stability of the human embryonal kidney cell line 293 by cytogenetic and STR profiling approaches
Bylund L; Kytölä S; Lui WO; Larsson C; Weber G
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2003;278(50):49685-49690
High extracellular Ca²⁺ hyperpolarizes human parathyroid cells via Ca²⁺-activated K⁺ channels
Välimäki S; Höög A; Larsson C; Farnebo LO; Bränström R
Article: CANCER CELL. 2003;4(5):405-413
The t(1;3) breakpoint-spanning involved in clear cell renal cell genes LSAMP and NORE1 are carcinomas
Chen JD; Lui WO; Vos MD; Clark GJ; Takahashi M; Schoumans J; Khoo SK; Petillo D; Lavery T; Sugimura J; Astuti D; Zhang C; Kagawa S; Maher ER; Larsson C; Alberts AS; Kanayama HO; Teh BT
Article: NEW ENGLAND JOURNAL OF MEDICINE. 2003;349(18):1722-1729
Somatic and germ-line mutations of the HRPT2 gene in sporadic parathyroid carcinoma
Shattuck TM; Välimäki S; Obara T; Gaz RD; Clark OH; Shoback D; Wierman ME; Tojo K; Robbins CM; Carpten JD; Farnebo LO; Larsson C; Arnold A
Article: ONCOLOGY REPORTS. 2003;10(5):1641-1645
Evaluation of immunohistochemical parameters as prognostic markers in malignant fibrous histiocytoma
Åhlén J; Weng WWH; Brosjö O; Von Rosen A; Larsson O; Larsson C
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2003;88(9):4440-4445
Involvement of the PAX8/peroxisome proliferator-activated receptor γ rearrangement in follicular thyroid tumors
Dwight T; Thoppe SR; Foukakis T; Lui WO; Wallin G; Höög A; Frisk T; Larsson C; Zedenius J
Article: BRITISH JOURNAL OF CANCER. 2003;89(4):720-726
Gain of 17q in malignant fibrous histiocytoma is associated with a longer disease-free survival and a low risk of developing distant metastasis
Weng WH; Åhlén J; Lui WO; Brosjö O; Pang ST; von Rosen A; Auer G; Larsson O; Larsson C
Article: CLINICAL ENDOCRINOLOGY. 2003;59(1):129-135
Multiple endocrine neoplasia type 1 (MEN1): genetic and clinical analysis in the Southern Chinese
Tso AWK; Rong R; Lo CY; Tan KCB; Tiu SC; Wat NMS; Xu JY; Villablanca A; Larsson C; Teh BT; Lam KSL
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2003;22(5):1003-1007
Mutation analysis of the BRG1 gene in prostate cancer clinical samples
Valdman A; Nordenskjöld A; Fang XL; Naito A; Al-Shukri S; Larsson C; Ekman P; Li CD
Article: ONCOGENE. 2003;22(14):2215-2222
Characteristic sequence motifs located at the genomic breakpoints of the translocation t(X;18) in synovial sarcomas
Wei YK; Sun MH; Nilsson G; Dwight T; Xie YT; Wang J; Hou YY; Larsson O; Larsson C; Zhu XZ
Article: THYROID. 2003;13(4):371-380
MIB-1 index in thyroid tumors:: A predictor of the clinical course in papillary thyroid carcinoma?
Kjellman P; Wallin G; Höög A; Auer G; Larsson C; Zedenius J
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2003;11(4):529-533
Difference between Swedish and Japanese men in the association between AR CAG repeats and prostate cancer suggesting a susceptibility-modifying locus overlapping the androgen receptor gene
Li CD; Grönberg H; Matsuyama H; Weber G; Nordenskjöld M; Naito K; Bergh A; Bergerheim U; Damber JE; Larsson C; Ekman P
Article: MODERN PATHOLOGY. 2003;16(3):246-255
Ki-67 and hTERT expression can aid in the distinction between malignant and benign pheochromocytoma and paraganglioma
Elder EE; Xu D; Höög A; Enberg U; Pisa P; Gruber A; Larsson C; Bäckdahl M
Article: CANCER GENETICS. 2003;141(1):43-48
Molecular cytogenetic characterization of four commonly used cell lines derived from Hodgkin lymphoma
Berglund M; Flordal E; Gullander J; Lui WO; Larsson C; Lagercrantz S; Enblad G
Article: NATURE GENETICS. 2002;32(4):676-680
HRPT2, encoding parafibromin, is mutated in hyperparathyroidism-jaw tumor syndrome
Carpten JD; Robbins CM; Villablanca A; Forsberg L; Presciuttini S; Bailey-Wilson J; Simonds WF; Gillanders EM; Kennedy AM; Chen JD; Agarwal SK; Sood R; Jones MP; Moses TY; Haven C; Petillo D; Leotlela PD; Harding B; Cameron D; Pannett AA; Höög A; Heath H; James-Newton LA; Robinson B; Zarbo RJ; Cavaco BM; Wassif W; Perrier ND; Rosen IB; Kristoffersson U; Turnpenny PD; Farnebo LO; Besser GM; Jackson CE; Morreau H; Trent JM; Thakker RV; Marx SJ; Teh BT; Larsson C; Hobbs MR
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2002;21(6):1197-1204
Identifying cancer-related genes in nasopharyngeal carcinoma cell lines using DNA and mRNA expression profiling analyses
Guo X; Lui WO; Qian CN; Chen JD; Gray SG; Rhodes D; Haab B; Stanbridge E; Wang HM; Hong MH; Min HQ; Larsson C; Teh BT
Article: CANCER GENETICS. 2002;139(1):38-43
Clonal development of a blastoid mantle cell lymphoma studied with comparative genomic hybridization
Flordal E; Berglund M; Rosenquist R; Erlanson M; Enblad G; Roos G; Larsson C; Lagercrantz S
Article: AMERICAN JOURNAL OF PATHOLOGY. 2002;161(4):1299-1306
Independent genetic events associated with the development of multiple parathyroid tumors in patients with primary hyperparathyroidism
Dwight T; Nelson AE; Theodosopoulos G; Richardson AL; Learoyd DL; Philips J; Delbridge L; Zedenius J; Teh BT; Larsson C; Marsh DJ; Robinson BG
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2002;21(4):727-735
Distinct target regions for chromosome 1p deletions in parathyroid adenomas and carcinomas
Välimäki S; Forsberg L; Farnebo LO; Larsson C
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2002;147(3):313-322
Involvement of the MEN1 gene locus in familial isolated hyperparathyroidism
Villablanca A; Wassif WS; Smith T; Höög A; Vierimaa O; Kassem M; Dwight T; Forsberg L; Du Q; Learoyd D; Jones K; Stranks S; Juhlin C; Teh BT; Carling T; Robinson B; Larsson C
Article: GENES CHROMOSOMES AND CANCER. 2002;35(1):74-80
Silencing of the PTEN tumor-suppressor gene in anaplastic thyroid cancer
Frisk T; Foukakis T; Dwight T; Lundberg J; Höög A; Wallin G; Eng C; Zedenius J; Larsson C
Article: MODERN PATHOLOGY. 2002;15(8):807-816
Chromosomal imbalances in diffuse large B-cell lymphoma detected by comparative genomic hybridization
Berglund M; Enblad G; Flordal E; Lui WO; Backlin C; Thunberg U; Sundström C; Roos G; Allander SV; Erlanson M; Rosenquist R; Larsson C; Lagercrantz S
Article: GENES CHROMOSOMES AND CANCER. 2002;34(3):325-332
Alterations of the SDHD gene locus in midgut carcinoids, Merkel cell carcinomas, pheochromocytomas, and abdominal paragangliomas
Kytölä S; Nord B; Elder EE; Carling T; Kjellman M; Cedermark B; Juhlin C; Höög A; Isola J; Larsson C
Article: ONCOGENE. 2002;21(26):4181-4190
Co-existence of SYT-SSX1 and SYT-SSX2 fusions in synovial sarcomas
Yang K; Lui WO; Xie YT; Zhang AJ; Skytting B; Mandahl N; Larsson C; Larsson O
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2002;20(6):1161-1165
Aberrations of centrosomes in adrenocortical tumors
Roshani L; Fujioka K; Auer G; Kjellman M; Lagercrantz S; Larsson C
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2002;146(5):619-627
Genetic analysis of lithium-associated parathyroid tumors
Dwight T; Kytölä S; Teh BT; Theodosopoulos G; Richardson AL; Philips J; Twigg S; Delbridge L; Marsh DJ; Nelson AE; Larsson C; Robinson BG
Article: BMC CANCER. 2002;2:5
Chromosomal aberrations in benign and malignant Bilharzia-associated bladder lesions analyzed by comparative genomic hybridization
Fadl-Elmula I; Kytola S; El Leithy M; Abdel-Hameed M; Mandahl N; Elagib A; Ibrahim M; Larsson C; Heim S
Article: ONCOGENE. 2002;21(7):1117-1122
Selective loss of chromosome 11 in pheochromocytomas associated with the VHL syndrome
Lui WO; Chen JD; Gläsker S; Bender BU; Madura C; Khoo SK; Kort E; Larsson C; Neumann HPH; Teh BT
Article: CLINICAL ENDOCRINOLOGY. 2002;56(2):261-269
Genetic and clinical characterization of sporadic cystic parathyroid tumours.
Villablanca A; Farnebo F; Teh BT; Farnebo L-O; Höög A; Larsson C
Article: MAMMALIAN GENOME. 2002;13(1):20-23
Characterization of a putative murine mitochondrial transporter homology of hMRS3/4
Li FY; Leibiger B; Leibiger I; Larsson C
Article: CLINICAL ENDOCRINOLOGY. 2002;56(2):259-267
Genetic and clinical characterization of sporadic cystic parathyroid tumours
Villablanca A; Farnebo F; Teh BT; Farnebo LO; Höög A; Larsson C
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2001;8(6):681-689
Differential expression of multiple alternative spliceforms of the Men1 tumor suppressor gene in mouse
Forsberg L; Zablewska B; Piehl F; Weber G; Lagercrantz S; Gaudray P; Höög C; Larsson C
Article: KIDNEY INTERNATIONAL. 2001;60(5):1666-1675
Heterogeneous expression of receptor mRNAs in parathyroid glands of secondary hyperparathyroidism
Välimäki S; Farnebo F; Forsberg L; Larsson C; Farnebo LO
Article: EXPERIMENTAL CELL RESEARCH. 2001;270(1):88-95
Methylation changes in the human IGF2 P3 promoter parallel IGF2 expression in the primary tumor, established cell line, and xenograft of a human hepatoblastoma
Eriksson T; Frisk T; Gray SG; von Schweinitz D; Pietsch T; Larsson C; Sandstedt B; Ekström TJ
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2001;9(10):747-752
Mapping of the second locus for the Van der Woude syndrome to chromosome 1p34
Koillinen H; Wong FK; Rautio J; Ollikainen V; Karsten A; Larson O; Teh BT; Huggare J; Lahermo P; Larsson C; Kere J
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2001;145(4):415-420
Homozygous inactivation of the MEN1 gene as a specific somatic event in a case of secondary hyperparathyroidism
Forsberg L; Villablanca A; Välimäki S; Farnebo F; Farnebo LO; Lagercrantz S; Larsson C
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2001;19(3):451-457
High level amplification of 1p32-33 and 2p22-24 in small cell lung carcinomas
Lui WO; Tanenbaum DM; Larsson C
Article: GENES CHROMOSOMES AND CANCER. 2001;32(1):43-49
Gain of 1q and loss of 9q21.3-q32 are associated with a less favorable prognosis in papillary thyroid carcinoma
Kjellman P; Lagercrantz S; Höög A; Wallin G; Larsson C; Zedenius J
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2001;286(2):426-431
Menin interacts directly with the homeobox-containing protein Pem
Lemmens IH; Forsberg L; Pannett AAJ; Meyen E; Piehl F; Turner JJO; Van de Ven WJM; Thakker RV; Larsson C; Kas K
Article: WORLD JOURNAL OF SURGERY. 2001;25(7):948-956
Genetic background of adrenocortical tumor development
Kjellman M; Larsson C; Bäckdahl M
Article: NATURE GENETICS. 2001;28(3):223-231
Human mitochondrial DNA deletions associated with mutations in the gene encoding Twinkle, a phage T7 gene LF-like protein localized in mitochondria
Spelbrink JN; Li FY; Tiranti V; Nikali K; Yuan QP; Tariq M; Wanrooij S; Garrido N; Comi G; Morandi L; Santoro L; Toscano A; Fabrizi GM; Somer H; Croxen R; Beeson D; Poulton L; Suomalainen A; Jacobs HT; Zeviani M; Larsson C
Article: INTERNATIONAL JOURNAL OF CANCER. 2001;92(6):824-831
Characterization of chromosomal abnormalities in uroepithelial carcinomas by G-banding, spectral karyotyping and fish analysis
Fadl-Elmula I; Kytölä S; Pan Y; Lui WO; Derienzo G; Forsberg L; Mandahl N; Gorunova L; Bergerheim USR; Heim S; Larsson C
Article: CANCER GENETICS. 2001;127(2):128-133
A highly aggressive primitive mesenchymal tumor with a translocation (1;19)(q12;q13.2)
Lui WO; Wejde J; Tani E; Brosjö O; Kytölä S; Larsson C
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2001;18(6):1219-1225
CGH alterations in medullary thyroid carcinomas in relation to the RET M918T mutation and clinical outcome
Frisk T; Zedenius J; Lundberg J; Wallin G; Kytölä S; Larsson C
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2001;66(5):297-304
Identification of numerical and structural chromosome aberrations in 15 high hyperdiploid childhood acute lymphoblastic leukemias using spectral karyotyping
Nordgren A; Farnebo F; Johansson B; Holmgren G; Forestier E; Larsson C; Söderhäll S; Nordenskjöld M; Blennow E
Article: AMERICAN JOURNAL OF PATHOLOGY. 2001;158(5):1803-1808
Comparative genomic hybridization identifies loss of 18q22-qter as an early and specific event in tumorigenesis of midgut carcinoids
Kytölä S; Höög A; Nord B; Cedermark B; Frisk T; Larsson C; Kjellman M
Article: FEBS LETTERS. 2001;494(1-2):79-84
Characterization of a novel human putative mitochondrial transporter homologous to the yeast mitochondrial RNA splicing proteins 3 and 4
Li FY; Nikali K; Gregan J; Leibiger I; Leibiger B; Schweyen R; Larsson C; Suomalainen A
Article: CANCER GENETICS. 2001;126(1):1-7
Aberrations of chromosome 8 in 16 breast cancer cell lines by comparative genomic hybridization, fluorescence in situ hybridization, and spectral karyotyping
Rummukainen J; Kytölä S; Karhu R; Farnebo F; Larsson C; Isola JJ
Article: JOURNAL OF MEDICAL GENETICS. 2001;38(3):165-170
Association of a novel constitutional translocation t(1q;3q) with familial renal cell carcinoma
Kanayama H; Lui WO; Takahashi M; Naroda T; Kedra D; Wong FI; Kuroki Y; Nakahori Y; Larsson C; Kagawa S; Teh BT
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2001;7(3):289-294
Dominantly inherited familial myasthenia gravis as a separate genetic entity without involvement of defined candidate gene loci
Li FY; Szobor A; Croxen R; Anselmo V; Yuan QP; Lindblad K; Schalling M; Komoly S; Beeson D; Larsson C
Article: GENES CHROMOSOMES AND CANCER. 2001;30(2):187-195
5q11, 8p11, and 10q22 are recurrent chromosomal breakpoints in prostate cancer cell lines
Pan Y; Lui WO; Nupponen N; Larsson C; Isola J; Visakorpi T; Bergerheim USR; Kytölä S
Article: GENE. 2001;262(1-2):51-59
Characterisation of the human APC1, the largest subunit of the anaphase-promoting complex
Jörgensen PM; Gräslund S; Betz R; Ståhl S; Larsson C; Höög C
Article: SARCOMA. 2001;5(3):143-149
Malignant Fibrous Histiocytoma, Aggressive Fibromatosis and Benign Fibrous Tumors Express mRNA for the Metalloproteinase Inducer EMMPRIN and the Metalloproteinases MMP-2 and MT1-MMP.
Ahlén J; Enberg U; Larsson C; Larsson O; Frisk T; Brosjö O; Rosen A; Bäckdahl M
Article: CYTOGENETIC AND GENOME RESEARCH. 2001;92(1-2):89-96
Chromosomal distribution, localization and expression of the human endogenous retrovirus ERV9
Svensson AC; Raudsepp T; Larsson C; Di Cristofano A; Chowdhary B; La Mantia G; Rask L; Andersson G
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2000;6(4):469-474
Expression analysis of RET and the GDNF/GFRa-1 and NTN/GFRa-2 ligand complexes in pheochromocytomas and paragangliomas
Edström E; Frisk T; Farnebo F; Höög A; Bäckdahl M; Larsson C
Article: BRITISH JOURNAL OF CANCER. 2000;83(8):1020-1025
Comparative genomic hybridization reveals population-based genetic alterations in hepatoblastomas
Gray SG; Kytölä S; Matsunaga T; Larsson C; Ekström TJ
Article: NATURE BIOTECHNOLOGY. 2000;18(9):1001-1005
Loss-of-heterozygosity analysis of small-cell lung carcinomas using single-nucleotide polymorphism arrays
Lindblad-Toh K; Tanenbaum DM; Daly MJ; Winchester E; Lui WO; Villapakkam A; Stanton SE; Larsson C; Hudson TJ; Johnson BE; Lander ES; Meyerson M
Article: INTERNATIONAL JOURNAL OF CANCER. 2000;87(4):463-467
Malignant melanoma in patients with multiple endocrine neoplasia type 1 and involvement of the MEN1 gene in sporadic melanoma
Nord B; Platz A; Smoczynski K; Kytölä S; Robertson G; Calender A; Murat A; Weintraub D; Burgess J; Edwards M; Skogseid B; Owen D; Lassam N; Hogg D; Larsson C; Teh BT
Article: AMERICAN JOURNAL OF PATHOLOGY. 2000;157(2):579-586
Patterns of chromosomal imbalances in parathyroid carcinomas
Kytölä S; Farnebo F; Obara T; Isola J; Grimelius L; Farnebo LO; Sandelin K; Larsson C
Article: CLINICAL ENDOCRINOLOGY. 2000;53(2):205-211
Phenotype and phenocopy: the relationship between genotype and clinical phenotype in a single large family with multiple endocrine neoplasia type 1 (MEN 1)
Burgess JR; Nord B; David R; Greenaway TM; Parameswaran V; Larsson C; Shepherd JJ; Teh BT
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2000;6(2):161-169
Expression of genes involved with cell cycle control, cell growth and chromatin modification are altered in hepatoblastomas
Gray SG; Hartmann W; Eriksson T; Ekström C; Holm S; Kytölä S; von Schweinitz D; Pietsch T; Larsson C; Kogner P; Sandstedt B; Ekström TJ
Article: CLINICAL ENDOCRINOLOGY. 2000;53(1):85-92
Loss of heterozygosity in sporadic parathyroid tumours:: involvement of chromosome 1 and the MEN1 gene locus in 11q13.
Dwight T; Twigg S; Delbridge L; Wong FK; Farnebo F; Richardson AL; Nelson A; Zedenius J; Philips J; Larsson C; Teh BT; Robinson B
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2000;6(1):73-81
Characterization of the human peroxisome proliferator activated receptor delta gene and its expression
Skogsberg J; Kannisto K; Roshani L; Gagné E; Hamsten A; Larsson C; Ehrenborg E
Article: CLEFT PALATE-CRANIOFACIAL JOURNAL. 2000;37(4):357-362
Linkage analysis of candidate regions in Swedish nonsyndromic cleft lip with or without cleft palate families
Wong FK; Hagberg C; Karsten A; Larson O; Gustavsson M; Huggare J; Larsson C; Teh BT; Linder-Aronson S
Article: GENES CHROMOSOMES AND CANCER. 2000;28(3):308-317
Chromosomal alterations in 15 breast cancer cell lines by comparative genomic hybridization and spectral karyotyping
Kytölä S; Rummukainen J; Nordgren A; Karhu R; Farnebo F; Isola J; Larsson C
Article: CANCER GENETICS. 2000;119(2):109-112
Balanced translocation (3;7)(p25;q34):: Another mechanism of tumorigenesis in follicular thyroid carcinoma?
Lui WO; Kytölä S; Ånfalk L; Larsson C; Farnebo LO
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2000;142(6):643-649
Expression of RET and its ligand complexes, GDNF/GFRalpha-1 and NTN/GFRalpha-2, in medullary thyroid carcinomas
Frisk T; Farnebo F; Zedenius J; Grimelius L; Höög A; Wallin G; Larsson C
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2000;5(5):485-492
New chromosomal breakpoints in non-Hodgkin's lymphomas revealed by spectral karyotyping and G-banding
Nordgren A; Sorensen AG; Tinggaard-Pedersen N; Blennow E; Larsson C; Lagercrantz S
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2000;85(4):1449-1454
A genotypic and histopathological study of a large Dutch kindred with hyperparathyroidism-jaw tumor syndrome
Haven CJ; Wong FK; van Dam EWCM; van der Luijt R; van Asperen C; Jansen J; Rosenberg C; de Wit M; Roijers J; Hoppener J; Lips CJ; Larsson C; Teh BT; Morreau H
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2000;5(3):235-240
Spectral karyotyping and chromosome banding studies of primary breast carcinomas and their lymph node metastases
Adeyinka A; Kytölä S; Mertens F; Pandis N; Larsson C
Article: AMERICAN JOURNAL OF PATHOLOGY. 2000;156(2):651-659
Comparative genomic hybridization reveals frequent losses of chromosomes 1p and 3q in pheochromocytomas and abdominal paragangliomas, suggesting a common genetic etiology
Edström E; Mahlamäki E; Nord B; Kjellman M; Karhu R; Höög A; Goncharov N; Teh BT; Bäckdahl M; Larsson C
Article: HEMATOLOGY JOURNAL. 2000;1(2):95-101
Detailed characterization of a complex karyotype in a patient with primary plasma cell leukaemia using multicolour spectral karyotyping and micro-FISH.
Nordgren A; Farnebo F; Björkholm M; Sahlén S; Porwit-MacDonald A; Osby E; Kytölä S; Larsson C; Nordenskjöld M; Blennow E
Article: MAMMALIAN GENOME. 2000;11(1):78-80
Molecular characterization of human and murine C11orf5, a new member of the FAUNA gene cluster
Lemmens IH; Farnebo F; Piehl F; Merregaert J; Van de Ven WJM; Larsson C; Kas K
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2000;5(1):33-41
Modulating IGFBP-3 expression by trichostatin A:: Potential therapeutic role in the treatment of hepatocellular carcinoma
Gray SG; Kytölä S; Lui WO; Larsson C; Ekström TJ
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2000;85(1):165-167
Familial isolated hyperparathyroidism as a variant of multiple endocrine neoplasia type 1 in a large Danish pedigree
Kassem M; Kruse TA; Wong FK; Larsson C; Teh BT
Article: NEUROLOGY. 1999;53(6):1265-1271
Mapping of autosomal dominant progressive external ophthalmoplegia to a 7-cM critical region on 10q24
Li FY; Tariq M; Croxen R; Morten K; Squier W; Newsom-Davis J; Beeson D; Larsson C
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 1999;84(10):3775-3780
Alternative genetic pathways in parathyroid tumorigenesis
Farnebo F; Kytölä S; Teh BT; Dwight T; Wong FK; Höög A; Elvius M; Wassif WS; Thompson NW; Farnebo LO; Sandelin K; Larsson C
Article: GENES CHROMOSOMES AND CANCER. 1999;26(1):35-39
Sporadic follicular thyroid tumors show loss of a 200-kb region in 11q13 without evidence for mutations in the MEN1 gene
Nord B; Larsson C; Wong FK; Wallin G; Teh BT; Zedenius J
Article: GENES CHROMOSOMES AND CANCER. 1999;25(4):349-353
Low frequency of numerical chromosomal aberrations in follicular thyroid tumors detected by comparative genomic hybridization
Frisk T; Kytölä S; Wallin G; Zedenius J; Larsson C
Article: FEBS LETTERS. 1999;450(3):210-216
Suppression of the neoplastic phenotype by transfection of phospholipase C β 3 to neuroendocrine tumor cells
Stålberg P; Wang S; Larsson C; Weber C; Öberg K; Gobl A; Skogseid B
Article: MAMMALIAN GENOME. 1999;10(4):376-380
Characterization and chromosomal localization of the human insulin-like growth factor binding protein 6 gene
Ehrenborg E; Zazzi H; Lagercrantz S; Granqvist M; Hillerbrand U; Allander SV; Larsson C; Luthman H
Article: ACTA ODONTOLOGICA SCANDINAVICA. 1999;57(2):72-76
Clinical and genetic studies of Van der Woude syndrome in Sweden
Wong FK; Karsten A; Larson O; Huggare J; Hagberg C; Larsson C; Teh BT; Linder-Aronson S
Article: WORLD JOURNAL OF SURGERY. 1999;23(3):237-242
Gelatinase A and membrane-type 1 matrix metalloproteinase mRNA:: Expressed in adrenocortical cancers but not in adenomas
Kjellman M; Enberg U; Höög A; Larsson C; Holst M; Farnebo LO; Sato H; Bäckdahl M
Article: CLINICAL ENDOCRINOLOGY. 1999;50(3):343-346
No overrepresentation of congenital adrenal hyperplasia in patients with adrenocortical tumours
Kjellman M; Holst M; Bäckdahl M; Larsson C; Farnebo LO; Wedell A
Article: GENES CHROMOSOMES AND CANCER. 1999;24(3):175-182
Distinct deleted regions on chromosome segment 16q23-24 associated with metastases in prostate cancer
Li CD; Berx G; Larsson C; Auer G; Aspenblad U; Pan Y; Sundelin B; Ekman P; Nordenskjöld M; van Roy F; Bergerheim USR
Article: CLINICAL ENDOCRINOLOGY. 1999;50(2):191-196
Genetic studies of a family with hereditary hyperparathyroidism jaw tumour syndrome
Wassif WS; Farnebo F; Teh BT; Moniz CF; Li FY; Harrison JD; Peters TJ; Larsson C; Harris P
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 1999;84(2):730-735
Genotyping of adrenocortical tumors:: Very frequent deletions of the MEN1 locus in 11q13 and of a 1-centimorgan region in 2p16
Kjellman M; Roshani L; Teh BT; Kallioniemi OP; Höög A; Gray S; Farnebo LO; Holst M; Bäckdahl M; Larsson C
Article: WORLD JOURNAL OF SURGERY. 1999;23(1):68-74
Evaluation of retinoblastoma and Ki-67 immunostaining as diagnostic markers of benign and malignant parathyroid disease
Farnebo F; Auer G; Farnebo LO; Teh BT; Twigg S; Aspenblad U; Thompson NW; Grimelius L; Larsson C; Sandelin K
Article: CYTOGENETIC AND GENOME RESEARCH. 1999;87(3-4):225-232
Characterization of chromosomal abnormalities in prostate cancer cell lines by spectral karyotyping
Pan Y; Kytölä S; Farnebo F; Wang N; Lui WO; Nupponen N; Isola J; Visakorpi T; Bergerheim USR; Larsson C
Article: FEBS LETTERS. 1998;441(2):261-265
Targeted disruption of the mouse phospholipase C β3 gene results in early embryonic lethality
Wang S; Gebre-Medhin S; Betsholtz C; Stålberg P; Zhou YH; Larsson C; Weber G; Feinstein R; Öberg K; Gobl A; Skogseid B
Article: ONCOGENE. 1998;17(19):2485-2493
Characterization of the mouse Men1 gene and its expression during development
Stewart C; Parente F; Piehl F; Farnebo F; Quincey D; Silins G; Bergman L; Carle GF; Lemmens I; Grimmond S; Xian CZ; Khodei S; Teh BT; Lagercrantz J; Siggers P; Calender A; Van de Vem V; Kas K; Weber G; Hayward N; Gaudray P; Larsson C
Article: GENOMICS. 1998;52(2):245-246
Human histone deacetylase 2, HDAC2 (human RPD3), is localized to 6q21 by radiation hybrid mapping
Betz R; Gray SG; Ekström C; Larsson C; Ekström TJ
Article: GENOMICS. 1998;52(2):201-204
Restriction map of a YAC and cosmid contig encompassing the oculopharyngeal muscular dystrophy candidate region on chromosome 14q11.2-q13
Xie YG; Rochefort D; Brais B; Howard H; Han FY; Gou LP; Maciel P; The BT; Larsson C; Rouleau GA
Article: MAMMALIAN GENOME. 1998;9(8):660-665
Expression and chromosomal localization of the Requiem gene
Gabig TG; Crean CD; Klenk A; Long HY; Copeland NG; Gilbert DJ; Jenkins NA; Quincey D; Parente F; Lespinasse F; Carle GF; Gaudray P; Zhang CX; Calender A; Hoeppener J; Kas K; Thakker RV; Farnebo F; Teh BT; Larsson C; Piehl F; Lagercrantz J; Khodaei S; Carson E; Weber G
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 1998;83(8):2627-2630
Alterations of the MEN1 gene in sporadic parathyroid tumors
Farnebo F; Teh BT; Kytölä S; Svensson A; Phelan C; Sandelin K; Thompson NW; Höög A; Weber G; Farnebo LO; Larsson C
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 1998;83(8):2621-2626
Mutation analysis of the MEN1 gene in multiple endocrine neoplasia type 1, familial acromegaly and familial isolated hyperparathyroidism
Teh BT; Kytölä S; Farnebo F; Bergman L; Wong FK; Weber G; Hayward N; Larsson C; Skogseid B; Beckers A; Phelan C; Edwards M; Epstein M; Alford F; Hurley D; Grimmond S; Silins G; Walters M; Stewart C; Cardinal J; Khodaei S; Parente F; Tranebjaerg L; Jorde R; Menon J; Khir A; Tan TT; Chan SP; Zaini A; Khalid BAK; Sandelin K; Thompson N; Brandi ML; Warth M; Stock J; Leisti J; Cameron D; Shepherd JJ; Öberg K; Nordenskjöld M; Salmela P
Article: ANNALS OF SURGERY. 1998;228(1):99-105
Thymic carcinoids in multiple endocrine neoplasia type 1
Teh BT; Zedenius J; Kytölä S; Skogseid B; Trotter J; Choplin H; Twigg S; Farnebo F; Giraud S; Cameron D; Robinson B; Calender A; Larsson C; Salmela P
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1998;247(2):357-360
Expression of the BCL6 gene in the pre- and postnatal mouse
Bajalica-Lagercrantz S; Piehl F; Farnebo F; Larsson C; Lagercrantz J
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 1998;1398(2):157-163
A comparative study of the expression patterns for vegf, vegf-b/vrf and vegf-c in the developing and adult mouse
Lagercrantz J; Farnebo F; Larsson C; Tvrdik T; Weber G; Piehl F
Article: GENOMICS. 1998;50(2):251-259
A putative human zinc-finger gene (ZFPL1) on 11q13, highly conserved in the mouse and expressed in exocrine pancreas -: The European Consortium on MEN 1
Höppener JWM; De Wit MJ; Simarro-Doorten AY; Roijers JFM; van Herrewaarden HMC; Lips CJM; Parente F; Quincey D; Gaudray P; Khodaei S; Weber G; Teh B; Farnebo F; Larsson C; Zhang CX; Calender A; Pannett AAJ; Forbes SA; Bassett JHT; Thakker RV; Lemmens I; Van de Ven WJM; Kas K
Article: GENOMICS. 1998;50(2):213-221
Cloning and characterization of ZNF189, a novel human Kruppel-like zinc finger gene localized to chromosome 9q22-q31
Odeberg J; Rosok O; Gudmundsson GH; Ahmadian A; Roshani L; Williams C; Larsson C; Pontén F; Uhlén M; Åsheim HC; Lundeberg J
Article: DIABETES. 1998;47(6):976-979
Insulin receptor substrate-2 amino acid polymorphisms are not associated with random type 2 diabetes among Caucasians
Bernal D; Almind K; Yenush L; Ayoub M; Zhang YT; Rosshani L; Larsson C; Pedersen O; White MF
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 1998;83(6):2114-2120
Familial isolated hyperparathyroidism maps to the hyperparathyroidism-jaw tumor locus in 1q21-q32 in a subset of families
Teh BT; Farnebo F; Twigg S; Höög A; Kytölä S; Korpi-Hyövälti E; Wong FK; Nordenström J; Grimelius L; Sandelin K; Robinson B; Farnebo LO; Larsson C
Article: NEUROLOGY. 1998;50(4):1067-1073
Charcot-Marie-Tooth disease and Noonan syndrome with giant proximal nerve hypertrophy
Silburn PA; Nicholson GA; Teh BT; Blair IP; Pollard JD; Nolan PJ; Larsson C; Boyle RS
Article: MAMMALIAN GENOME. 1998;9(4):310-311
Mapping of the human Ca²⁺ channel β₄ subunit to 2q22-23 and its expression in developing mouse
Betz R; Leibiger B; Farnebo F; Lagercrantz S; Piehl F; Leibiger I; Larsson C
Article: CANCER RESEARCH. 1998;58(5):1004-1012
Consortium study on 1280 breast carcinomas:: Allelic loss on chromosome 17 targets subregions associated with family history and clinical parameters
Phelan CM; Borg Å; Cuny M; Crichton DN; Baldersson T; Andersen TI; Caligo MA; Lidereau R; Lindblom A; Seitz S; Kelsell D; Hamann K; Rio P; Thorlacius S; Papp J; Olah E; Ponder B; Bignon YJ; Scherneck S; Barkardottir R; Borresen-Dale AL; Eyfjörd J; Theillet C; Thompson AM; Devilee P; Larsson C
Article: GENES CHROMOSOMES AND CANCER. 1998;21(3):260-264
Bilateral multiple renal oncocytomas and cysts associated with a constitutional translocation (8;9)(q24.1;q34.3) and a rare constitutional VHL missense substitution
Teh BT; Blennow E; Giraud S; Sahlen S; Hii SI; Brookwell R; Nordenskjold HM; Larsson C; Nicol D
Article: ONCOGENE. 1998;16(4):481-487
Identification of two distinct deleted regions on chromosome 13 in prostate cancer
Li CD; Larsson C; Futreal A; Lancaster J; Phelan C; Aspenblad U; Sundelin B; Liu Y; Ekman P; Auer G; Bergerheim USR
Article: CANCER EPIDEMIOLOGY. 1998;22(6):544-548
A rapid method for DNA extraction from fine-needle aspiration biopsies of thyroid tumors, and subsequent RET mutation analysis
Zedenius J; Dwight T; Robinson BG; Delbridge L; Backdahl M; Wallin G; Larsson C; Weber G
Article: GENOMICS. 1997;46(1):78-85
Cloning and characterization of freac-9 (FKHL17), a novel kidney-expressed human forkhead gene that maps to chromosome 1p32-p34
Ernstsson S; Betz R; Lagercrantz S; Larsson C; Ericksson S; Cederberg A; Carlsson P; Enerback S
Article: CANCER RESEARCH. 1997;57(21):4710-4713
Somatic deletions and mutations in the Cowden disease gene, PTEN, in sporadic thyroid tumors
Dahia PLM; Marsh DJ; Zheng ZM; Zedenius J; Komminoth P; Frisk T; Wallin G; Parsons R; Longy M; Larsson C; Eng C
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1997;239(3):878-883
Novel splicing of an IGF2 polymorphic region in Human adrenocortical carcinomas
Gray SG; Kjellman M; Larsson C; Ekstrom TJ
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 1997;82(10):3481-3486
Tumor-specific decreased expression of calcium sensing receptor messenger ribonucleic acid in sporadic primary hyperparathyroidism
Farnebo F; Enberg U; Grimelius L; Backdahl M; Schalling M; Larsson C; Farnebo LO
Article: HUMAN GENETICS. 1997;100(5-6):657-665
The European Consortium on MEN1 - Linkage disequilibrium studies in multiple endocrine neoplasia type 1 (MEN1)
Bassett JHD; Pannett AAJ; Forbes SA; Thakker RV; McCarthy M; Read AP; Teh BT; Larsson C; Kytola S; Leisti J; Salmela P; Weber G; Giraud S; Zhang CX; Calender A; Hoppener JWM; vanAmstel HKP; Lips CJM; Kas K; VandeVen WJM; Gaudray P
Article: GENOMICS. 1997;44(3):344-346
Chromosome localization, sequence analysis, and expression pattern identify FKHL 18 as a novel human forkhead gene
Cederberg A; Betz R; Lagercrantz S; Larsson C; Hulander M; Carlsson P; Enerback S
Article: GENOMICS. 1997;44(1):94-100
Construction of a 1.2-Mb sequence-ready contig of chromosome 11q13 encompassing the multiple endocrine neoplasia type 1 (MEN1) gene - The European consortium on type 1 (MEN1) gene
Lemmens I; Merregaert J; VandeVen WJM; Kas K; Zhang CX; Giraud S; Wautot V; Buisson N; DeWitte K; Salandre J; Lenoir G; Calender A; Parente F; Quincey D; Courseaux A; Carle GF; Gaudray P; DeWit MJ; Lips CJM; Hoppener JWM; Khodaei S; Grant AL; Weber G; Kytola S; Teh BT; Farnebo F; Grimmond S; Phelan C; Larsson C; Forbes SA; Bassett JHD; Pannett AAJ; Thakker RV
Article: HUMAN GENETICS. 1997;100(3-4):481-485
Mapping of the gene encoding the B56 beta subunit of protein phosphatase 2A (PPP2R5B) to a 0.5-Mb region of chromosome 11q13 and its exclusion as a candidate gene for multiple endocrine neoplasia type 1 (MEN1)
Forbes SA; Pannett AAJ; Bassett JHD; Harding B; Wooding C; Thakker RV; Butler R; Ogilvie D; Anand R; Gaudray P; Weber G; Larsson C; Zhang CX; Calender A; Hoppener JWM; Lips CJM; Kas K
Article: HUMAN MOLECULAR GENETICS. 1997;6(7):1177-1183
Identification of the multiple endocrine neoplasia type 1 (MEN1) gene
Lemmens I; VandeVen WJM; Kas K; Zhang CX; Giraud S; Wautot V; Buisson N; DeWitte K; Salandre J; Lenoir G; Pugeat M; Calender A; Parente F; Quincey D; Gaudray P; DeWit MJ; Lips CJM; Hoppener JWM; Khodaei S; Grant AL; Weber G; Kytola S; Teh BT; Farnebo F; Phelan C; Hayward N; Larsson C; Pannett AAJ; Forbes SA; Bassett JHD; Thakker RV
Article: MAMMALIAN GENOME. 1997;8(7):513-515
The mouse homologs of RELA and MLK3 are located within a 120-kb fragment on Chromosome 19
Fernandes M; Poirier C; Lassam NJ; Larsson C; Guenet JL; Gaudray P; Carle GF
Article: HUMAN GENETICS. 1997;99(6):776-780
Fine mapping of the MLK-3 gene within 11q13 and its exclusion as the MEN1 susceptibility gene
Lassam NJ; Lin Z; Shennan MG; Courseaux A; Teh BT; Gaudray P; Larsson C
Article: BRITISH JOURNAL OF SURGERY. 1997;163(5):331-337
Allelic loss on chromosome 11 is uncommon in parathyroid glands of patients with hypercalcaemic secondary hyperparathyroidism
Farnebo F; Farnebo LO; Nordenstrom J; Larsson C
Article: JOURNAL OF CLINICAL NEUROSCIENCE. 1997;4(2):176-180
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy
Sullivan AA; Teh BT; Jeavons S; Schalling M; Silburn P; Larsson C; Boyle R
Article: THE LANCET. 1997;349(9055):848-849
Familial non-VHL non-papillary clear-cell renal cancer
Teh BT; Giraud S; Sari NF; Hii SI; Bergerat JP; Larsson C; Limacher JM; Nicol D
Article: HUMAN GENETICS. 1997;99(3):342-349
Differential loss of heterozygosity in familial, sporadic, and uremic hyperparathyroidism
Farnebo F; Teh BT; Dotzenrath C; Wassif WS; Svensson A; White I; Betz R; Goretzki P; Sandelin K; Farnebo LO; Larsson C
Article: CANCER RESEARCH. 1997;57(3):500-503
Differential loss of heterozygosity in the region of the Cowden locus within 10q22-23 in follicular thyroid adenomas and carcinomas
Marsh DJ; Zheng ZM; Zedenius J; Kremer H; Padberg GW; Larsson C; Longy M; Eng C
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 1997;82(2):486-492
A kindred with a variant of multiple endocrine neoplasia type 1 demonstrating frequent expression of pituitary tumors but not linked to the multiple endocrine neoplasia type 1 locus at chromosome region 11q13
Stock JL; Warth MR; Teh BT; Coderre JA; Overdorf JH; Baumann G; Hintz RL; Hartman ML; Seizinger BR; Larsson C; Aronin N
Article: CLINICAL GENETICS. 1997;51(1):52-55
Oculopharyngeal muscular dystrophy (OPMD) - Report and genetic studies of an Australian kindred
Teh BT; Sullivan AA; Farnebo F; Zander C; Li FY; Strachan N; Schalling M; Larsson C; Sandstrom P
Article: ACTA DERMATO-VENEREOLOGICA. 1997;77(1):4-9
Fine mapping of the locus for nevoid basal cell carcinoma syndrome on chromosome 9q
Unden AB; StahleBackdahl M; Holmberg E; Larsson C; Toftgard R
Article: MEDICINE (UNITED KINGDOM). 1997;76(1):21-29
Clinicopathologic studies of thymic carcinoids in multiple endocrine neoplasia type 1
Teh BT; McArdle J; Chan SP; Menon J; Hartley L; Pullan P; Ho J; Khir A; Wilkinson S; Larsson C; Cameron D; Shepherd J
Article: HUMAN GENETICS. 1996;99(1):130-132
Exclusion of the phosphoinositide-specific phospholipase C beta 3 (PLCB3) gene as a candidate for multiple endocrine neoplasia type 1
Weber G; Grimmond S; Lagercrantz J; Friedman E; Phelan C; Carson E; Hayward N; Jacobovitz O; Nordenskjold M; Larsson C
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 1996;81(12):4204-4211
Autosomal dominant primary hyperparathyroidism and jaw tumor syndrome associated with renal hamartomas and cystic kidney disease: Linkage to 1q21-q32 and loss of the wild type allele in renal hamartomas
Teh BT; Farnebo F; Kristoffersson U; Sundelin B; Cardinal J; Axelson R; Yap A; Epstein M; Heath H; Cameron D; Larsson C
Article: GENOMICS. 1996;37(3):354-365
Definition of the minimal MEN1 candidate area based on a 5-Mb integrated map of proximal 11q13. The European Consortium on Men1, (GENEM 1; Groupe d'Etude des Néoplasies Endocriniennes Multiples de type 1).
Courseaux A; Grosgeorge J; Gaudray P; Pannett AA; Forbes SA; Williamson C; Bassett D; Thakker RV; Teh BT; Farnebo F; Shepherd J; Skogseid B; Larsson C; Giraud S; Zhang CX; Salandre J; Calender A
Article: ARCHIVES OF SURGERY. 1996;131(11):1230-1232
Sporadic primary hyperparathyroidism in the setting of multiple endocrine neoplasia type 1
Teh BT; McArdle J; Parameswaran V; David R; Larsson C; Shepherd J
Article: CANCER RESEARCH. 1996;56(18):4219-4223
Genetic aberrations in adrenocortical tumors detected using comparative genomic hybridization correlate with tumor size and malignancy
Kjellman M; Kallioniemi OP; Karhu R; Hoog A; Farnebo LO; Auer G; Larsson C; Backdahl M
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 1996;81(9):3194-3196
Allelic loss of the retinoblastoma tumor suppressor gene: A marker for aggressive parathyroid tumors?
Dotzenrath C; Teh BT; Farnebo F; Cupisti K; Svensson A; Toell A; Goretzki P; Larsson C
Article: GENOMICS. 1996;35(3):633-635
A human homologue of the rat rab geranylgeranyl transferase beta subunit on chromosome 1p22-p31
Sanders R; BinIslam K; Betz R; Larsson C; Smith CIE
Article: GENOMICS. 1996;34(1):63-68
The human mammary-derived growth inhibitor (MDGI) gene: Genomic structure and mutation analysis in human breast tumors
Phelan CM; Larsson C; Baird S; Futreal PA; Ruttledge MH; Morgan K; Tonin P; Hung H; Korneluk RG; Pollak MN; Narod SA
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 1996;81(4):1312-1317
Clustered inactivating mutations and benign polymorphisms of the calcium receptor gene in familial benign hypocalciuric hypercalcemia suggest receptor functional domains
Heath H; Odelberg S; Jackson CE; Teh BT; Hayward N; Larsson C; Buist NRM; Krapcho KJ; Hung BC; Capuano IV; Garrett JE; Leppert MF
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1996;220(1):147-152
Expression of the VEGF-related factor gene in pre- and postnatal mouse
Lagercrantz J; Larsson C; Grimmond S; Fredriksson M; Weber G; Piehl F
Article: HUMAN GENETICS. 1996;97(3):299-303
Deletions of the long arm of chromosome 10 in progression of follicular thyroid tumors
Zedenius J; Wallin G; Svensson A; Bovee J; Hoog A; Backdahl M; Larsson C
Article: GENOMICS. 1996;31(3):380-384
Isolation and characterization of a novel gene close to the human phosphoinositide-specific phospholipase C beta 3 gene on chromosomal region 11q13
Lagercrantz J; Carson E; Larsson C; Nordenskjold M; Weber G
Article: THYROID. 1996;6(1):1-9
Alterations of p53 and expression of WAF1/p21 in human thyroid tumors
Zedenius J; Larsson C; Wallin G; Backdahl M; Aspenblad U; Hoog A; Borresen AL; Auer G
Article: WORLD JOURNAL OF SURGERY. 1996;20(1):101-106
Stromal fibroblasts adjacent to invasive thyroid tumors: Expression of gelatinase a but not stromelysin 3 mRNA
Zedenius J; StahleBackdahl M; Enberg U; Grimelius L; Larsson C; Wallin G; Backdahl M
Article: NEUROREPORT. 1995;6(18):2542-2544
Expression of the phosphoinositide-specific phospholipase C beta 3 gene in the rat
Lagercrantz J; Piehl F; Nordenskjold M; Larsson C; Weber G
Article: GENOMICS. 1995;30(3):464-469
Chromosomal localization of six human forkhead genes, freac-1(FKHL5), -3(FKHL7), -4(FKHL8), -5(FKHL9), -6(FKHL10), and -8(FKHL12)
Larsson C; Hellqvist M; Pierrou S; White I; Enerback S; Carlsson P
Article: SURGERY. 1995;118(6):1077-1082
ADRENAL LESION IN MULTIPLE ENDOCRINE NEOPLASIA TYPE-1
SKOGSEID B; RASTAD J; GOBL A; LARSSON C; BACKLIN K; JUHLIN C; AKERSTROM G; OBERG K
Article: SURGERY. 1995;118(6):924-930
HYPERPARATHYROIDISM OF MULTIPLE ENDOCRINE NEOPLASIA TYPE-1 - CANDIDATE GENE AND PARATHYROID CALCIUM SENSING PROTEIN EXPRESSION
CARLING T; RASTAD J; RIDEFELT P; GOBL A; HELLMAN P; OBERG K; RASK L; LARSSON C; JUHLIN C; AKERSTROM G; SKOGSEID B
Article: JOURNAL OF INTERNAL MEDICINE. 1995;238(3):249-253
GENETIC-MAPPING OF THE MULTIPLE ENDOCRINE NEOPLASIA TYPE-1 LOCUS AT 11Q13
TEH BT; CARDINAL J; SHEPHERD J; HAYWARD NK; WEBER G; CAMERON D; LARSSON C
Article: JOURNAL OF INTERNAL MEDICINE. 1995;238(3):245-248
CANDIDATE GENES FOR MULTIPLE ENDOCRINE NEOPLASIA TYPE-1
LAGERCRANTZ J; LARSSON C; GRIMMOND S; SKOGSEID B; GOBL A; FRIEDMAN E; CARSON E; PHELAN C; OBERG K; NORDENSKJOLD M; HAYWARD NK; WEBER G
Article: JOURNAL OF INTERNAL MEDICINE. 1995;238(3):239-244
MOLECULAR TOOLS FOR PRESYMPTOMATIC TESTING IN MULTIPLE ENDOCRINE NEOPLASIA TYPE-1
LARSSON C; CALENDER A; GRIMMOND S; GIRAUD S; HAYWARD NK; TEH B; FARNEBO F
Article: LEUKEMIA. 1995;9(8):1313-1317
REARRANGEMENT OF PROXIMAL 11Q13 BAND IN A CMML IN ACUTE TRANSFORMATION
COURSEAUX A; GROSGEORGE J; GARNIER G; LARSSON C; AYRAUD N; GAUDRAY P; RAYNAUD SD
Article: HUMAN GENETICS. 1995;96(1):27-32
ALLELOTYPING OF FOLLICULAR THYROID-TUMORS
ZEDENIUS J; WALLIN G; SVENSSON A; GRIMELIUS L; HOOG A; LUNDELL G; BACKDAHL M; LARSSON C
Article: GENES CHROMOSOMES AND CANCER. 1995;13(3):203-210
HIGH ALLELE LOSS RATES AT 17Q12-Q21 IN BREAST AND OVARIAN-TUMORS FROM BRCA1-LINKED FAMILIES
CORNELIS RS; NEUHAUSEN SL; JOHANSSON O; ARASON A; KELSELL D; PONDER BAJ; TONIN P; HAMANN U; LINDBLOM A; LALLE P; LONGY M; OLAH E; SCHERNECK S; BIGNON YJ; SOBOL H; CHANGCLAUDE J; LARSSON C; SPURR N; BORG A; BARKARDOTTIR RB; NAROD S; DEVILEE P
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 1995;56(6):1443-1449
FAMILIAL PERIODIC CEREBELLAR-ATAXIA WITHOUT MYOKYMIA MAPS TO A 19-CM REGION ON 19P13
TEH BT; SILBURN P; LINDBLAD K; BETZ R; BOYLE R; SCHALLING M; LARSSON C
Article: GENOMICS. 1995;26(3):467-472
GENOMIC ORGANIZATION AND COMPLETE CDNA SEQUENCE OF THE HUMAN PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE-C BETA-3 GENE (PLCB3)
LAGERCRANTZ J; CARSON E; PHELAN C; GRIMMOND S; ROSEN A; DARE E; NORDENSKJOLD M; HAYWARD NK; LARSSON C; WEBER G
Article: JOURNAL OF IMMUNOLOGY. 1995;154(3):1265-1272
MOLECULAR-CLONING, CHARACTERIZATION, AND CHROMOSOMAL LOCALIZATION OF A HUMAN LYMPHOID TYROSINE KINASE RELATED TO MURINE BLK
ISLAM KB; RABBANI H; LARSSON C; SANDERS R; SMITH CIE
Article: LAKARTIDNINGEN. 1995;92(4):269-275
[The first breast cancer gene isolated. Safer risk assessment for affected families].
Iselius L; Larsson C; Lindblom A; Sandelin K; Wickman M; Wilking N
Article: CYTOGENETIC AND GENOME RESEARCH. 1995;71(3):257-259
ASSIGNMENT OF THE MOUSE HOMOLOG OF A HUMAN MEN1 CANDIDATE GENE, PHOSPHOLIPASE C-BETA-3 (PLCB3), TO CHROMOSOME REGION 19B BY FISH
GOBL AE; CHOWDHARY BP; SHU W; ERIKSSON L; LARSSON C; WEBER G; OBERG K; SKOGSEID B
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 1995;56(1):254-264
AN EVALUATION OF GENETIC-HETEROGENEITY IN 145 BREAST-CANCER OVARIAN-CANCER FAMILIES
NAROD SA; FORD D; DEVILEE P; BARKARDOTTIR RB; LYNCH HT; SMITH SA; PONDER BAJ; WEBER BL; GARBER JE; BIRCH JM; CORNELIS RS; KELSELL DP; SPURR NK; SMYTH E; HAITES N; SOBOL H; BIGNON YJ; CHANGCLAUDE J; HAMANN U; LINDBLOM A; BORG A; PIVER MS; GALLION HH; STRUEWING JP; WHITTEMORE A; TONIN P; GOLDGAR DE; EASTON DF; MILNER B; ALLAN L; SIMARD J; ROMMENS J; MCGILLIVRAY B; GREEN R; IVES E; BOYD N; ROSEN B; COLE D; MORGAN K; MOSLEHI R; PONDER B; PETO J; SMITH S; STRATTON M; DICIOCCIO RA; GALLION H; SANTIBANEZKOREF MS; TEARE MD; EVANS DG; STOPPALYONNET D; LALLE P; BONAITI C; ESSIOUX L; GIRODET C; MAUGARDLOUBOUTIN C; NICOLLEAU G; LONGY M; TOULOUSE C; HORSTEIN I; BIRNBAUM D; EISINGER F; KARENGUEVEN F; NOGUCHI T; HARDOUIN A; RIO P; MACHELARDROUMAGNAC M; NOGUES C; COHENHAGUENAUER O; LORTHOLARY A; BAY JO; ARASON A; BARKDARDOTTIR RB; EGILSSON V; BISHOP DT; KELSELL D; MURDAY VA; SOLOMON E; SPURR N; TURNER G; LENOIR G; FEUNTEUN J; LYNCH H; LYNCH J; WATSON P; CONWAY T; BONNARDEL C; SEROVA O; TORCHARD D; LARSSON C; VASEN H; VANLEEUWEN I; CORNELISSE CJ; STEEL M; PORTER D; COHEN BB; CAROTHERS A; CANNONALBRIGHT LA; GOLDGAR D; SKOLNICK M; BECHER H; JOHANNSSON O; WEBER B; COLLINS F; BOEHNKE M; GARBER J; LI F
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 1992;33(4):861-869
Gene-specific promoter hypermethylation without global hypomethylation in follicular thyroid cancer
Lee J-J; Geli J; Larsson C; Wallin G; Karimi M; Zedenius J; Hoog A; Foukakis T
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 1992;34(2):481-492
Loss of expression for the Wnt pathway components adenomatous polyposis coli and glycogen synthase kinase 3-β in parathyroid carcinomas
Juhlin CC; Haglund F; Villablanca A; Forsberg L; Sandelin K; Branstrom R; Larsson C; Hoog A
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Corrigendum: NATURE METABOLISM. 2022;4(10):1421
Impaired oxygen-sensitive regulation of mitochondrial biogenesis within the von Hippel-Lindau syndrome (June, 10.1038/s42255-022-00593-x, 2022)
Li S; Li W; Yuan J; Bullova P; Wu J; Zhang X; Liu Y; Plescher M; Rodriguez J; Bedoya-Reina OC; Jannig PR; Valente-Silva P; Yu M; Henriksson MA; Zubarev RA; Smed-Sorensen A; Suzuki CK; Ruas JL; Holmberg J; Larsson C; Christofer Juhlin C; von Kriegsheim A; Cao Y; Schlisio S
Review: THE LANCET DIABETES AND ENDOCRINOLOGY. 2021;9(1):13-21
Maternal and fetal outcomes in phaeochromocytoma and pregnancy: a multicentre retrospective cohort study and systematic review of literature.
Bancos I; Atkinson E; Eng C; Young WF; Neumann HPH; International Pheochromocytoma and Pregnancy Study
Review: ONCOGENE. 2019;38(34):6172-6183
Mechanisms underlying the activation of TERT transcription and telomerase activity in human cancer: old actors and new players
Yuan X; Larsson C; Xu D
Letter: CLINICAL ENDOCRINOLOGY. 2018;88(2):343-345
Telomerase reverse transcriptase promoter hypermethylation is associated with metastatic disease in abdominal paraganglioma
Svahn F; Juhlin CC; Paulsson JO; Fotouhi O; Zedenius J; Larsson C; Stenman A
Published conference paper: SURGERY. 2017;161(6):1667-1674
Overexpression of cytochrome P450 2A6 in adrenocortical carcinoma
Murtha TD; Brown TC; Rubinstein JC; Haglund F; Juhlin C; Larsson C; Korah R; Carling T
Letter: ENDOCRINE-RELATED CANCER. 2015;22(3):L9-L11
TERT promoter mutations are rare in parathyroid tumors
Haglund F; Juhlin CC; Brown T; Ghaderi M; Liu T; Stenman A; Dinets A; Prasad M; Korah R; Xu D; Carling T; Larsson C
Letter: CLINICAL ENDOCRINOLOGY. 2010;73(4):552-553
Lack of S37A CTNNB1/β-catenin mutations in a Swedish cohort of 98 parathyroid adenomas
Haglund F; Andreasson A; Nilsson I-L; Hoog A; Larsson C; Juhlin CC
Meeting abstract: EJC SUPPLEMENTS. 2010;8(5):187
Altered expression of miR-205 affects cell proliferation in human cervical cancer
Xie H; Caramuta S; Larsson C; Lui WO
Meeting abstract: EJC SUPPLEMENTS. 2010;8(5):185
Role of microRNAs and microRNA machinery in the pathogenesis of diffuse large B-cell lymphomas
Caramuta S; Berglund M; Ozata D; Akcakaya P; Georgii-Hemming P; Xie H; Enblad G; Larsson C; Lui WO
Meeting abstract: EJC SUPPLEMENTS. 2010;8(5):224
The involvement of miR-483 and its host gene IGF2 in development of adrenal cortical carcinoma
Ozata D; Caramuta S; Akcakaya P; Xie HONG; Backdahl M; Larsson C; Lui W
Meeting abstract: BLOOD. 2004;104(11):431A
DLEU2, located within the CLL 13q14 deletion locus, encodes an antisense RNA for the putative bicistronic RFP2/LEU5 gene in humans and mouse
Corcoran MM; Hammarsund M; Zhu CY; Lerner M; Kapanadze B; Larsson C; Forsberg L; Ibbotson RE; Einhorn S; Oscier DG; Grander D; Sangfelt O
Published conference paper: WORLD JOURNAL OF SURGERY. 2002;26(8):965-971
Loss of heterozygosity on the short arm of chromosome 1 in pheochromocytoma and abdominal paraganglioma
Elder EE; Nord B; Carling T; Juhlin C; Bäckdahl M; Höög A; Larsson C
Published conference paper: WORLD JOURNAL OF SURGERY. 2002;26(8):907-913
Genetic screening for MEN1 mutations in families presenting with familial primary hyperparathyroidism
Perrier ND; Villablanca A; Larsson C; Wong M; Ituarte P; Teh BT; Clark OH
Published conference paper: BRITISH JOURNAL OF SURGERY. 2001;88(4):557-563
Expression of the RET proto-oncogene in papillary thyroid carcinoma and its correlation with clinical outcome
Kjellman P; Learoyd DL; Messina M; Weber G; Höög A; Wallin G; Larsson C; Robinson BG; Zedenius J
Letter: JOURNAL OF MEDICAL GENETICS. 2001;38(3):185-189
Founder effect in multiple endocrine neoplasia type 1 (MEN 1) in Finland
Kytölä S; Villablanca A; Ebelings T; Nord B; Larsson C; Höög A; Wong FK; Välimäki M; Vierimaa O; Teh BT; Salmela PI; Leisti J
Review: SEMINARS IN CANCER BIOLOGY. 2000;10(4):299-312
Multiple endocrine neoplasia type 1
Wong FK; Burgess J; Nordenskjöld M; Larsson C; Teh BT
Editorial comment: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2000;85(5):1752-1754
Editorial: Dissecting the genetics of hyperparathyroidism - New clues from an old friend
Larsson C
Published conference paper: SURGERY. 1999;126(6):1183-1187
Expression of matrix metalloproteinase gelatinase A messenger ribonucleic acid in parathyroid carcinomas
Farnebo F; Svensson A; Thompson NW; Bäckdahl M; Grimelius L; Larsson C; Farnebo LO; Sandelin K
Review: ANTICANCER RESEARCH. 1999;19(6A):4715-4728
Tumor suppressor genes (TSG)
Teh BT; Larsson C; Nordenskjöld M
Letter: JOURNAL OF MEDICAL GENETICS. 1999;36(4):348-349
Familial testicular cancer:: lack of evidence for trinucleotide repeat expansions and association with PKD1 in one family
Teh BT; Linblad K; Nord B; Kytölä S; Schalling M; Larsson C; Rapley E; Biggs P; Huddart R; Stratton M; Hii S; Nicol D
Published conference paper: SURGERY. 1998;124(6):1094-1099
Decreased expression of calcium-sensing receptor messenger ribonucleic acids in parathyroid adenomas
Farnebo F; Höög A; Sandelin K; Larsson C; Farnebo LO
Letter: AMERICAN JOURNAL OF HUMAN GENETICS. 1998;63(5):1544-1549
A family with isolated hyperparathyroidism segregating a missense MEN1 mutation and showing loss of the wild-type alleles in the parathyroid tumors
Teh BT; Esapa CT; Houlston R; Grandell U; Farnebo F; Nordenskjöld M; Pearce CJ; Carmichael D; Larsson C; Harris PE
Published conference paper: JOURNAL OF INTERNAL MEDICINE. 1998;243(6):441-446
The search for the MEN1 gene
Lemmes I; Van de Ven WJM; Kas K; Zhang CX; Giraud S; Wautot V; Buisson N; Pugeat M; Peix JL; Caldener A; Parente F; Quincey D; Courseaux A; Carle GF; Gaudray P; De Wit MJ; Lips CJM; Höppener JWM; Khodaei S; Grant AL; Weber G; Teh BT; Farnebo F; Kytölä S; Grimmond S; Phelan C; Larsson C; Bassett JHD; Forbes DA; Pannett AAJ; Thakker RV
Published conference paper: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 1998;841:181-183
Congenital myasthenic syndromes - Studies of the AChR and other candidate genes
Beeson D; Newland C; Croxen R; Buckel A; Li FY; Larsson C; Tariq M; Vincent A; Newsom-Davis J
Letter: AMERICAN JOURNAL OF NEURORADIOLOGY. 1997;18(5):991-992
Gene identification in autosomal dominant disorders
Teh BT; Lagercrantz J; Weber G; Larsson C
Published conference paper: HORMONE RESEARCH IN PAEDIATRICS. 1997;47(4-6):179-184
Multiple endocrine neoplasia type 1 and the search for the genetic trigger
Farnebo F; Jarhult J; Farnebo LO; Nilsson O; Teh BT; Lagercrantz J; Weber G; Sandelin K; Larsson C
Letter: NATURE GENETICS. 1996;13(2):238-240
BRCA2 mutations in primary breast and ovarian cancers
Lancaster JM; Wooster R; Mangion J; Phelan CM; Cochran C; Gumbs C; Seal S; Barfoot R; Collins N; Bignell G; Patel S; Hamoudi R; Larsson C; Wiseman RW; Berchuck A; Iglehart JD; Marks JR; Ashworth A; Stratton MR; Futreal PA
Letter: NATURE GENETICS. 1996;13(1):120-122
Mutation analysis of the BRCA2 gene in 49 site-specific breast cancer families
Phelan CM; Lancaster JM; Tonin P; Gumbs C; Cochran C; Carter R; Ghadirian P; Perret C; Moslehi R; Dion F; Faucher MC; Dole K; Karimi S; Foulkes W; Lounis H; Warner E; Goss P; Anderson D; Larsson C; Narod SA; Futreal PA
Letter: NATURE GENETICS. 1996;12(3):309-311
Ovarian cancer risk in BRCA1 carriers is modified by the HRAS1 variable number of tandem repeat (VNTR) locus
Phelan CM; Rebbeck TR; Weber BL; Devilee P; Ruttledge MH; Lynch HT; Lenoir GM; Stratton MR; Easton DF; Ponder BAJ; CannonAlbright L; Larsson C; Goldgar DE; Narod SA
Published conference paper: EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY AND DIABETES. 1996;104:105-107
Molecular genetics of primary and secondary hyperparathyroidism
Dotzenrath C; Goretzki PE; Farnebo F; Teh BT; Weber G; Roher HD; Larsson C
Review: ANZ JOURNAL OF SURGERY. 1995;65(10):708-713
MULTIPLE ENDOCRINE NEOPLASIA TYPE-I - CLINICAL SYNDROME TO MOLECULAR-GENETICS
TEH BT; GRIMMOND S; SHEPHERD J; LARSSON C; HAYWARD N
Other: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 1995;80(10):3088-3090
MUTATIONS OF CODON-918 IN THE RET PROTOONCOGENE CORRELATE TO POOR-PROGNOSIS IN SPORADIC MEDULLARY-THYROID CARCINOMAS
ZEDENIUS J; LARSSON C; BERGHOLM U; BOVEE J; SVENSSON A; HALLENGREN B; GRIMELIUS L; BACKDAHL M; WEBER G; WALLIN G
Other: CANCER RESEARCH. 1995;55(11):2225-2231
TUMOR-SUPPRESSOR ACTIVITY OF THE GENE ENCODING MAMMARY-DERIVED GROWTH INHIBITOR
HUYNH HT; LARSSON C; NAROD S; POLLAK M
Other: HUMAN GENETICS. 1995;95(4):455-458
EXCLUSION OF THE 13-KDA RAPAMYCIN BINDING-PROTEIN GENE (FKBP2) AS A CANDIDATE GENE FOR MULTIPLE ENDOCRINE NEOPLASIA TYPE-1
GRIMMOND S; WEBER G; LARSSON C; WALTERS M; TEH B; SHEPHERD J; NORDENSKJOLD M; HAYWARD N
Other: HUMAN GENETICS. 1995;95(3):356-358
LOCALIZATION OF THE HUMAN SOLUBLE EPOXIDE HYDROLASE GENE (EPHX2) TO CHROMOSOMAL REGION 8P21-P12
LARSSON C; WHITE I; JOHANSSON C; STARK A; MEIJER J
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