Studier av depression och ångest där Translationell psykiatri medverkar

Fysisk aktivitet vid depression 

www.REGASSA.se

Skolmiljöns betydelse för ungdomars hälsa

https://ki.se/en/gph/research-project-kupol-knowledge-of-adolescents-mental-health-and-learning-ephir

Psykisk hälsa, arbete och relationer (PART)

http://snd.gu.se/sv/catalogue/study/SND0784

Kognitiv beteendeterapi vid social fobi

https://www.iterapi.se/sites/socialradsla/

Publikationer

Sirtuins and neuropeptide y downregulation in Flinders Sensitive Line rat model of depression.
Stiernborg M, Efstathopoulos P, Lennartsson A, Lavebratt C, Mathé AA
Acta Neuropsychiatr 2022 Apr;34(2):86-92

The cannabinoid receptor-1 gene interacts with stressful life events to increase the risk for problematic alcohol use.
Bornscheuer L, Lundin A, Forsell Y, Lavebratt C, Melas PA
Sci Rep 2022 03;12(1):4963

Physical exercise is associated with a reduction in plasma levels of fractalkine, TGF-β1, eotaxin-1 and IL-6 in younger adults with mobility disability.
Kumar P, Stiernborg M, Fogdell-Hahn A, Månsson K, Furmark T, Berglind D, Melas PA, Forsell Y, Lavebratt C
PLoS One 2022 ;17(2):e0263173

DNA methylation of the glucocorticoid receptor gene predicts substance use in adolescence: longitudinal data from over 1000 young individuals.
Raffetti E, Melas PA, Landgren AJ, Andersson F, Forsell Y, Lavebratt C, Galanti MR
Transl Psychiatry 2021 09;11(1):477

Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression.
Forstner AJ, Awasthi S, Wolf C, Maron E, Erhardt A, Czamara D, Eriksson E, Lavebratt C, Allgulander C, Friedrich N, Becker J, Hecker J, Rambau S, Conrad R, Geiser F, McMahon FJ, Moebus S, Hess T, Buerfent BC, Hoffmann P, Herms S, Heilmann-Heimbach S, Kockum I, Olsson T, Alfredsson L, Weber H, Alpers GW, Arolt V, Fehm L, Fydrich T, Gerlach AL, Hamm A, Kircher T, Pané-Farré CA, Pauli P, Rief W, Ströhle A, Plag J, Lang T, Wittchen HU, Mattheisen M, Meier S, Metspalu A, Domschke K, Reif A, Hovatta I, Lindefors N, Andersson E, Schalling M, Mbarek H, Milaneschi Y, de Geus EJC, Boomsma DI, Penninx BWJH, Thorgeirsson TE, Steinberg S, Stefansson K, Stefansson H, Müller-Myhsok B, Hansen TF, Børglum AD, Werge T, Mortensen PB, Nordentoft M, Hougaard DM, Hultman CM, Sullivan PF, Nöthen MM, Woldbye DPD, Mors O, Binder EB, Rück C, Ripke S, Deckert J, Schumacher J
Mol Psychiatry 2021 08;26(8):4179-4190

Genetics of response to cognitive behavior therapy in adults with major depression: a preliminary report.
Andersson E, Crowley JJ, Lindefors N, Ljótsson B, Hedman-Lagerlöf E, Boberg J, El Alaoui S, Karlsson R, Lu Y, Mattheisen M, Kähler AK, Svanborg C, Mataix-Cols D, Mattsson S, Forsell E, Kaldo V, Schalling M, Lavebratt C, Sullivan PF, Rück C
Mol Psychiatry 2019 04;24(4):484-490

MicroRNA 101b Is Downregulated in the Prefrontal Cortex of a Genetic Model of Depression and Targets the Glutamate Transporter SLC1A1 (EAAT3) in Vitro.
Wei YB, Melas PA, Villaescusa JC, Liu JJ, Xu N, Christiansen SH, Elbrønd-Bek H, Woldbye DP, Wegener G, Mathé AA, Lavebratt C
Int J Neuropsychopharmacol 2016 12;19(12):

Elevation of Il6 is associated with disturbed let-7 biogenesis in a genetic model of depression.
Wei YB, Liu JJ, Villaescusa JC, Åberg E, Brené S, Wegener G, Mathé AA, Lavebratt C
Transl Psychiatry 2016 08;6():e869

Telomerase dysregulation in the hippocampus of a rat model of depression: normalization by lithium.
Wei YB, Backlund L, Wegener G, Mathé AA, Lavebratt C
Int J Neuropsychopharmacol 2015 Jan;18(7):pyv002

Antidepressant-like effect of sodium butyrate is associated with an increase in TET1 and in 5-hydroxymethylation levels in the Bdnf gene.
Wei Y, Melas PA, Wegener G, Mathé AA, Lavebratt C
Int J Neuropsychopharmacol 2014 Oct;18(2):

Genetic and epigenetic associations of MAOA and NR3C1 with depression and childhood adversities.
Melas PA, Wei Y, Wong CC, Sjöholm LK, Åberg E, Mill J, Schalling M, Forsell Y, Lavebratt C
Int J Neuropsychopharmacol 2013 Aug;16(7):1513-28

Cortisol Concentration as Predictor of Tobacco Initiation in Adolescents: Results From a Population-Based Swedish Cohort.
Raffetti E, Landgren AJ, Andersson F, Donato F, Lavebratt C, Forsell Y, Galanti MR
J Adolesc Health 2021 Apr;68(4):758-764

Childhood adversity increases methylation in the GRIN2B gene.
Engdahl E, Alavian-Ghavanini A, Forsell Y, Lavebratt C, Rüegg J
J Psychiatr Res 2021 01;132():38-43

The Effect of Smartphone Apps Versus Supervised Exercise on Physical Activity, Cardiorespiratory Fitness, and Body Composition Among Individuals With Mild-to-Moderate Mobility Disability: Randomized Controlled Trial.
Berglind D, Yacaman-Mendez D, Lavebratt C, Forsell Y
JMIR Mhealth Uhealth 2020 02;8(2):e14615

Single-nucleotide polymorphism in the human TIA1 gene interacts with stressful life events to predict the development of pathological anxiety symptoms in a Swedish population.
Rayman JB, Melas PA, Schalling M, Forsell Y, Kandel ER, Lavebratt C
J Affect Disord 2020 01;260():597-603

Exercise Reduces Salivary Morning Cortisol Levels in Patients with Depression.
Rahman MS, Zhao X, Liu JJ, Torres EQ, Tibert B, Kumar P, Kaldo V, Lindefors N, Forsell Y, Lavebratt C
Mol Neuropsychiatry 2019 Feb;4(4):196-203

Association of Catechol-O-methyltransferase (COMT Val158Met) with future risk of cardiovascular disease in depressed individuals - a Swedish population-based cohort study.
Almas A, Forsell Y, Millischer V, Möller J, Lavebratt C
BMC Med Genet 2018 07;19(1):126

NR3C1 hypermethylation in depressed and bullied adolescents.
Efstathopoulos P, Andersson F, Melas PA, Yang LL, Villaescusa JC, Rȕegg J, Ekström TJ, Forsell Y, Galanti MR, Lavebratt C
Transl Psychiatry 2018 06;8(1):121

Neuropeptide Y, stressful life events and personality trait conscientiousness: Preliminary associations from a Swedish longitudinal study.
Melas PA, Guban P, Rahman MS, Lavebratt C, Forsell Y

Effects of internet-based cognitive behavioural therapy and physical exercise on sick leave and employment in primary care patients with depression: two subgroup analyses.
Kaldo V, Lundin A, Hallgren M, Kraepelien M, Strid C, Ekblom Ö, Lavebratt C, Lindefors N, Öjehagen A, Forsell Y
Occup Environ Med 2018 01;75(1):52-58
Psychiatry Res 2018 05;263():48-53

The serotonin transporter promoter variant (5-HTTLPR) and childhood adversity are associated with the personality trait openness to experience.
Rahman MS, Guban P, Wang M, Melas PA, Forsell Y, Lavebratt C
Psychiatry Res 2017 11;257():322-326

Stress, depressive status and telomere length: Does social interaction and coping strategy play a mediating role?
Liu JJ, Wei YB, Forsell Y, Lavebratt C
J Affect Disord 2017 11;222():138-145

BDNF Val66Met and childhood adversity on response to physical exercise and internet-based cognitive behavioural therapy in depressed Swedish adults.
Rahman MS, Millischer V, Zeebari Z, Forsell Y, Lavebratt C
J Psychiatr Res 2017 10;93():50-58

Twelve-week physical exercise does not have a long-lasting effect on kynurenines in plasma of depressed patients.
Millischer V, Erhardt S, Ekblom Ö, Forsell Y, Lavebratt C
Neuropsychiatr Dis Treat 2017 ;13():967-972

Interleukin-6 and depressive symptom severity in response to physical exercise.
Lavebratt C, Herring MP, Liu JJ, Wei YB, Bossoli D, Hallgren M, Forsell Y
Psychiatry Res 2017 06;252():270-276

School environment and mental health in early adolescence - a longitudinal study in Sweden (KUPOL).
Galanti MR, Hultin H, Dalman C, Engström K, Ferrer-Wreder L, Forsell Y, Karlberg M, Lavebratt C, Magnusson C, Sundell K, Zhou J, Almroth M, Raffetti E
BMC Psychiatry 2016 07;16():243

Path analysis of the chronicity of depression using the comprehensive developmental model framework.
Fandiño-Losada A, Bangdiwala SI, Lavebratt C, Forsell Y
Nord J Psychiatry 2016 Jul;70(5):380-91

hTERT genetic variation in depression.
Wei YB, Martinsson L, Liu JJ, Forsell Y, Schalling M, Backlund L, Lavebratt C
J Affect Disord 2016 Jan;189():62-9

Impact of Childhood Adversity and Vasopressin receptor 1a Variation on Social Interaction in Adulthood: A Cross-Sectional Study.
Liu JJ, Lou F, Lavebratt C, Forsell Y
PLoS One 2015 ;10(8):e0136436

Depression-associated ARNTL and PER2 genetic variants in psychotic disorders.
Liu JJ, Sudic Hukic D, Forsell Y, Schalling M, Ösby U, Lavebratt C
Chronobiol Int 2015 May;32(4):579-84