Neurobiologin vid anorexia nervosa
Syftet med vår forskning är att förstå de neurobiologiska mekanismer som förklarar hur självsvälten vid anorexia nervosa uppkommer och vidmakthålls.
I detta syfte studerar vi markörer i blod från individer med sjukdomen samt utför molekylära studier av experimentella modeller, däribland patientspecifika nervceller som genererats från stamceller, samt studerar medicinska register. Vi samarbetar med Centre for Eating Disorders Innovation (CEDI) på MEB, KI.
Team-ledare: Ida Nilsson
Medverkande inom Translationell psykiatri-gruppen:
Vincent Millischer
Anknuten till ForskningUtvalda publikationer
Maternal Eating Disorders, Body Mass Index, and Offspring Psychiatric Diagnoses.
Nilsson IAK, Ozsvar J, Gissler M, Lavebratt C
JAMA Netw Open 2024 Oct;7(10):e2440517
Exposures during pregnancy and at birth are associated with the risk of offspring eating disorders.
Ozsvar J, Gissler M, Lavebratt C, Nilsson IAK
Int J Eat Disord 2023 Aug;():
Plasma Concentrations of Short-Chain Fatty Acids in Active and Recovered Anorexia Nervosa.
Xu J, Landberg R, Lavebratt C, Bulik CM, Landén M, Nilsson IAK
Nutrients 2022 Dec;14(24):
Exploring the Mechanisms of Recovery in Anorexia Nervosa through a Translational Approach: From Original Ecological Measurements in Human to Brain Tissue Analyses in Mice.
Duriez P, Nilsson IAK, Le Thuc O, Alexandre D, Chartrel N, Rovere C, Chauveau C, Gorwood P, Tolle V, Viltart O
Nutrients 2021 Aug;13(8):
Serum profiling of anorexia nervosa: A 1H NMR-based metabolomics study.
Salehi M A, Nilsson IA, Figueira J, Thornton LM, Abdulkarim I, Pålsson E, Bulik CM, Landén M
Eur Neuropsychopharmacol 2021 Aug;49():1-10
Aberrant inflammatory profile in acute but not recovered anorexia nervosa.
Nilsson IAK, Millischer V, Göteson A, Hübel C, Thornton LM, Bulik CM, Schalling M, Landén M
Brain Behav Immun 2020 Aug;88():718-724
Epigenetic regulation of the cannabinoid receptor CB1 in an activity-based rat model of anorexia nervosa.
D'Addario C, Zaplatic E, Giunti E, Pucci M, Micioni Di Bonaventura MV, Scherma M, Dainese E, Maccarrone M, Nilsson IA, Cifani C, Fadda P
Int J Eat Disord 2020 May;53(5):432-446
Associations of Different Types of Maternal Diabetes and Body Mass Index With Offspring Psychiatric Disorders.
Kong L, Nilsson IAK, Brismar K, Gissler M, Lavebratt C
JAMA Netw Open 2020 Feb;3(2):e1920787
Hypothalamic Structural and Functional Imbalances in Anorexia Nervosa.
Florent V, Baroncini M, Jissendi-Tchofo P, Lopes R, Vanhoutte M, Rasika S, Pruvo JP, Vignau J, Verdun S, Johansen JE, Pigeyre M, Bouret SG, Nilsson IAK, Prevot V
Neuroendocrinology 2020 ;110(6):552-562
Plasma neurofilament light chain concentration is increased in anorexia nervosa.
Nilsson IAK, Millischer V, Karrenbauer VD, Juréus A, Salehi AM, Norring C, von Hausswolff-Juhlin Y, Schalling M, Blennow K, Bulik CM, Zetterberg H, Landén M
Transl Psychiatry 2019 Aug;9(1):180
The anx/anx Mouse - A Valuable Resource in Anorexia Nervosa Research.
Nilsson IAK
Front Neurosci 2019 ;13():59
Associations of Maternal Diabetes and Body Mass Index With Offspring Birth Weight and Prematurity.
Kong L, Nilsson IAK, Gissler M, Lavebratt C
JAMA Pediatr 2019 Apr;173(4):371-378