CAR T treatments in Sweden
SWECARNET collects information direct from treating clinicians to map the use of CAR T in Sweden.
The first CAR T to be manufactured in Sweden (and Europe) was in 2014 at Vecura, Stockholm, and was used for academic clinical trial in Uppsala. The first Standard of Care use of a commercial CAR T was in November 2019 at Karolinska University Hospital. There are now several treatment centres in Sweden and several products have been administered in clinical trial and/or standard of care.
SWECARNET collects information direct from treating clinicians to map the use of CAR T in Sweden. We will endeavour to keep this page as up to date as possible. If you would like a more recent version or more specific information, please feel free to make contact with Hanna Sjölund (SWECARNET coordinator).
Swedish CAR T/TCR treatments
The picture in text:
Data from SWECARNET 26-08-2024.
- Now: 230 patients.
- Currently treated nationally; 236 infusions (6 RI) – 11 children.
Abbreviations:
- SOC = Standard of Care - SOC.
- ACT = Academic Clinical Trial - ACT.
- ICT = Industry Clinical Trial - ICT.
- GMP = GMP manufacture.
- RI = Reinfusion.
Umeå (6 infusions):
- First SOC Dec 2023 – Now 6 patients.
Uppsala (68 infusions):
- Academic trial 3rd generation CAR T since 2014.
- First ACT 2014 – Now 39 patients.
- First SOC Nov 2020 – Now 27 patients.
- First ICT June 2023 – Now 2 patients.
Stockholm (70infusions):
- Manufacture 3rd generation CAR T since 2014 – Karolinska/Vecura – 39 GMP batches.
- First ICT Aug 2019 – Now 14 patients.
- First SOC Nov 2019 – Now 51 patients, 5 RI.
Örebro:
- Upcoming treatment center.
Linköping (16 infusions):
- First SOC Jan 2020 – Now 14 patients.
- First ICT Apr 2023 – Now 2 patients.
Gothenburg (22 infusions):
- First SOC Oct 2020 – Now 19 patients.
- First ICT Oct 2022 – Now 1 patient, 1 RI.
- First CUP Feb 2024 – Now 1 patient.
Lund (54 infusions):
- First SOC Jan 2020 – Now 51 patients.
- First ICT Nov 2021 – Now 3 patients.