CAR T treatments in Sweden

SWECARNET collects information direct from treating clinicians to map the use of CAR T in Sweden.

The first CAR T to be manufactured in Sweden (and Europe) was in 2014 at Vecura, Stockholm, and was used for academic clinical trial in Uppsala. The first Standard of Care use of a commercial CAR T was in November 2019 at Karolinska University Hospital. There are now several treatment centres in Sweden and several products have been administered in clinical trial and/or standard of care.

SWECARNET collects information direct from treating clinicians to map the use of CAR T in Sweden. We will endeavour to keep this page as up to date as possible. If you would like a more recent version or more specific information, please feel free to make contact with Hanna Sjölund (SWECARNET coordinator).

Swedish CAR T/TCR treatments

A map that shows the Swedish CAR T treatments. Also described in text below the picture.


The picture in text:

Data from SWECARNET 26-08-2024.

  • Now: 230 patients.
  • Currently treated nationally; 236 infusions (6 RI) – 11 children.

Abbreviations:

  • SOC = Standard of Care - SOC.
  • ACT = Academic Clinical Trial - ACT.
  • ICT = Industry Clinical Trial - ICT.
  • GMP = GMP manufacture.
  • RI = Reinfusion.

Umeå (6 infusions):

  • First SOC Dec 2023 – Now 6 patients.

Uppsala (68 infusions):

  • Academic trial 3rd generation CAR T since 2014.
  • First ACT 2014 – Now 39 patients.
  • First SOC Nov 2020 – Now 27 patients.
  • First ICT June 2023 – Now 2 patients.

Stockholm (70infusions):

  • Manufacture 3rd generation CAR T since 2014 – Karolinska/Vecura – 39 GMP batches.
  • First ICT Aug 2019 – Now 14 patients.
  • First SOC Nov 2019 – Now 51 patients, 5 RI.

Örebro:

  • Upcoming treatment center.

Linköping (16 infusions):

  • First SOC Jan 2020 – Now 14 patients.
  • First ICT Apr 2023 – Now 2 patients.

Gothenburg (22 infusions):

  • First SOC Oct 2020 – Now 19 patients.
  • First ICT Oct 2022 – Now 1 patient, 1 RI.
  • First CUP Feb 2024 – Now 1 patient.

Lund (54 infusions):

  • First SOC Jan 2020 – Now 51 patients.
  • First ICT Nov 2021 – Now 3 patients.