Research at the Department of Neuroscience
The Department of Neuroscience incorporates research groups dealing with different aspects of the function of the nervous system, both under normal conditions and during different diseases. The department has five main fields of research. Research projects include a broad range of studies at the molecular and cellular levels, the network level and at the level of the overall organization of the nervous system.
Scientists in this area use an interdisciplinary approach to understand the human mind. This theme encompasses imaging neuroscience, neurophysiology, computation, and experimental psychology.
Genetic and molecular basis of nervous system disorders
Research groups in this area study pathogenetic mechanisms of neurological and mental diseases, including Parkinson’s disease, motor neuron disorders, epilepsy, neuropathic pain, prion-related disorders, schizophrenia, depression, ADHD, drug addiction and narcolepsy. Cell cultures, animal models of disease, and human postmortem samples are utilized to identify novel strategies for neural repair and for the improvement of current pharmacological therapies.
Neural cells: development, biology and pathology
Scientists in this area study the development and differentiation of neurons and glial cells, with focus on the role of growth factors, genetic and epigenetic mechanisms. They further address neuronal functions such as synaptic mechanisms, endocytosis, and ion channel function.
Neural networks and behavior
This theme encompasses a broad range of scientists focused on defining the function and organization of circuits controlling behavior, from networks responsible for the execution of movement in the brainstem and spinal cord to planning and endocrine centers in the basal ganglia, hypothalamus and cortex.
Affiliated centers and programs
AIMES - Center for Advancement of Integrated Medical and Engineering Sciences
AIMES is a collaborative effort by KI and The Royal Institute of Technology, KTH to promote interdisciplinary research and its translation to societal use.
The Animal Behavior Core Facility (ABCF)
ABCF is the new core facility at Karolinska Institutet designed to provide optimal environment, state-of-the-art instrumentation and technical/educational support to perform behavioral tests ranging from basic phenotype characterization to advanced analyses.
International Neuroinformatics Coordinating Facility (INCF)
The International Neuroinformatics Coordinating Facility (INCF) is hosted by Karolinska Institutet and the Royal Institute of Technology.
The strategic research area neuroscience at Karolinska Institutet, Umeå University and KTH has the mission to integrate clinical and basic research and to foster a new generation of leaders and scientists in translational neuroscience.
The Swedish Medical Nanoscience Center
The Swedish Medical Nanoscience Center at Karolinska Institutet is an initiative aimed to promote efficient integration of cutting edge technologies and medical research.