Research Division of Medical systems bioengineering
The research at the division of Medical systems bioengineering focuses on developing new methods and molecular tools for biological research using novel materials and bioengineering. Examples include peptide decorated polymer scaffolds, DNA origami and microfluidic devices and the questions we focus on are cell-signalling and tissue development and regeneration.
Research interests
The research at the division for Medical systems bioengineering focuses on new bioengineering techniques and new materials for cell biology research. The goal of many of our projects is to develop new methods that will help us and others to better understand biological processes at the nanoscale and up. In particular we are interested in how to control and study cell behaviour through their ability to sense their microenvironment. To this end the three research groups in the division use different technological approaches: Nanoscale patterning of proteins using DNA origami. Novel DNA-based detection and imaging probes. Surface display of peptides and small molecules using polymer chemistry. Microfluidics and mesoscale patterning for in-vitro models using lithography. Electron microscopy, both CryoEM and negative stain. Atomic Force Microscopy for imaging and cell adhesion studies.
Research groups
Björn Högberg group
Synthetic biology and DNA origami tools for biomedicine.
Bjørt Kragesteen group
Molecular mechanisms governing oxygen homeostasis in development, evolution, and disease
Björn Reinius group
Gene silencing and activation.
Molly Stevens group
Exploring and engineering the cell-material interface.
Jussi Taipale group
Transcriptional regulatory code of normal and cancer genomes.
Ziegenhain lab
Central molecular processes in human cells.
Contact
Björn Reinius
Head of divisionVisiting address
Division of Medical systems bioengineering
Biomedicum, 9B, floor 9
171 65 Solna