Xuekang Qi

Om mig
Publikationer
Forskningsbidrag
Populärvetenskap och samverkan

Om mig

Postdoktor vid Institutionen för Onkologi-Patologi (OnkPat), Karolinska Institutet (2022–2026).
Tidigare arbetat som seniorforskare inom forskning och utveckling av antikropps–läkemedelskonjugat på Bio-Thera Solutions (2020–2022).
Disputerade vid Sun Yat-sen University Cancer Center (2015–2020) med fokus på protein–proteininteraktioner och signaltransduktion.

Forskningsbeskrivning

Använder nya kemiska, termiska och kvantitativa proteomiktekniker för att studera akut lymfatisk leukemi (ALL).

Artiklar

Journal article: BLOOD CANCER DISCOVERY. 2024;5(2_Supplement):p30
Abstract P30: Therapeutic activation of pre-B-cell receptor signaling in high-risk pediatric ALL: exploiting TCF3 and MYC-linked vulnerabilities
Leo IR; Post F; Struyf N; Qi X; Aswad L; Nguyen TT; Tamai M; Akahane K; Pokrovskaja-Tamm K; Erkers T; Inukai T; Lehtiö J; Jafari R
Journal article: CANCER RESEARCH. 2023;83(5_Supplement):p4-01-32-p4-01-32
Abstract P4-01-32: BAT8008, a novel Trop-2 ADC with strong bystander effect, for the treatment of Trop-2 positive cancer
Mei X; Tang W; Zhou X; Qi X; Mai S; Zhong Z; Li S; Fan J; Gan J; Tan B; Qi Y; Guo Y; Yu J-C; Li S
Journal article: CANCER RESEARCH. 2023;83(5_Supplement):p4-01-12-p4-01-12
Abstract P4-01-12: BAT8006, a novel FRα ADC with strong bystander effect, for the treatment of advanced solid tumor
mai S; Mei X; Tang W; Zhou X; qi X; Zhong Z; Li S; fan J; Gan J; Tan B; Qi Y; Guo Y; li S; Yu J-C
Article: CELL DEATH & DISEASE. 2019;10(2):58
SHROOM2 inhibits tumor metastasis through RhoA-ROCK pathway-dependent and -independent mechanisms in nasopharyngeal carcinoma
Yuan J; Chen L; Xiao J; Qi X-K; Zhang J; Li X; Wang Z; Han Y-F; Xiang T; Zhang Y; Chen M-Y; Bei J-X; Zeng Y-X; Feng L
Article: CELL DEATH & DISEASE. 2018;9(7):761
BET bromodomain inhibitor JQ1 preferentially suppresses EBV-positive nasopharyngeal carcinoma cells partially through repressing c-Myc
Li N; Yang L; Qi X-K; Lin Y-X; Xie X; He G-P; Feng Q-S; Liu L-R; Xie X; Zeng Y-X; Feng L
Article: CANCER RESEARCH. 2018;78(13):3469-3483
TNFRSF19 Inhibits TGFβ Signaling through Interaction with TGFβ Receptor Type I to Promote Tumorigenesis
Deng C; Lin Y-X; Qi X-K; He G-P; Zhang Y; Zhang H-J; Xu M; Feng Q-S; Bei J-X; Zeng Y-X; Feng L
Article: PLOS PATHOGENS. 2018;14(7):e1007208
Epstein-Barr virus activates F-box protein FBXO2 to limit viral infectivity by targeting glycoprotein B for degradation
Zhang H-J; Tian J; Qi X-K; Xiang T; He G-P; Zhang H; Yu X; Zhang X; Zhao B; Feng Q-S; Chen M-Y; Zeng M-S; Zeng Y-X; Feng L
Article: CANCER SCIENCE. 2018;109(5):1710-1722
Induction of chemokine (C-C motif) ligand 5 by Epstein-Barr virus infection enhances tumor angiogenesis in nasopharyngeal carcinoma
Ma W; Feng L; Zhang S; Zhang H; Zhang X; Qi X; Zhang Y; Feng Q; Xiang T; Zeng Y-X
Article: THERANOSTICS. 2018;8(8):2202-2216
OVOL2 links stemness and metastasis via fine-tuning epithelial-mesenchymal transition in nasopharyngeal carcinoma
Qi X-K; Han H-Q; Zhang H-J; Xu M; Li L; Chen L; Xiang T; Feng Q-S; Kang T; Qian C-N; Cai M-Y; Tao Q; Zeng Y-X; Feng L
Article: CANCER LETTERS. 2016;381(1):14-22
A novel Smac mimetic APG-1387 demonstrates potent antitumor activity in nasopharyngeal carcinoma cells by inducing apoptosis
Li N; Feng L; Han H-Q; Yuan J; Qi X-K; Lian Y-F; Kuang B-H; Zhang Y-C; Deng C-C; Zhang H-J; Yao Y-Y; Xu M; He G-P; Zhao B-C; Gao L; Feng Q-S; Chen L-Z; Yang L; Yang D; Zeng Y-X

Alla övriga publikationer

Patent: 2023
Antibody-drug conjugates and application thereof
Tang W; Qi X; Zhou X; Yan H; Li S; Fan J; Mai S; Yu J-C; Li S
Patent: 2022
Antibody-drug conjugates and uses thereof
Tang W; Zhou X; Mei X; Yan H; Li S; Fan J; Qi X; Yu J-C; Li S

Forskningsbidrag

KI Research Foundation Grants 2024-2025
1 January 2024 - 31 December 2025
Genetically engineered mouse model of nasopharyngeal carcinoma based on genetic susceptibility
National Natural Science Foundation of China
1 January 2019 - 31 December 2022
Epstein-Barr virus promotes vascular mimicry in nasopharyngeal carcinoma and its mechanism
National Natural Science Foundation of China
1 January 2019 - 31 December 2022
Epstein-Barr virus Infects Nasopharyngeal Epithelial Cells by Interaction of gHgL Dimer with Integrin α3β4 Subunit
National Natural Science Foundation of China
1 January 2018 - 31 December 2020
Study on BRCA1-mediated DNA damage repair pathway and chemosensitivity
National Natural Science Foundation of China
1 January 2017 - 31 December 2020

Om mig

Forskningsbeskrivning

Artiklar

Alla övriga publikationer

Forskningsbidrag

Nyheter från KI

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