Ulf Diczfalusy

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: JOURNAL OF LIPID RESEARCH. 2025;66(1):100698
A sterol panel for rare lipid disorders: sitosterolemia, cerebrotendinous xanthomatosis and Smith-Lemli-Opitz syndrome
Westbye AB; Dizdarevic LL; Dahl SR; Asprusten EA; Bliksrud YT; Sandblom AL; Diczfalusy U; Thorsby PM; Retterstol K
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022;23(23):15168
Pregnancy Increases CYP3A Enzymes Activity as Measured by the 4β-Hydroxycholesterol/Cholesterol Ratio
Mlugu EM; Minzi OM; Kamuhabwa AAR; Diczfalusy U; Aklillu E
Article: PHARMACOLOGY RESEARCH & PERSPECTIVES. 2021;9(6):e00884
Studies on CYP3A activity during the menstrual cycle as measured by urinary 6β-hydroxycortisol/cortisol
Bergstrom H; Lindahl A; Warnqvist A; Diczfalusy U; Ekstrom L; Bjorkhem-Bergman L
Article: CANCERS. 2021;13(18):4689
CYP3A Activity in End-of-Life Cancer Patients Measured by 4β-Hydroxycholesterol/cholesterol Ratio, in Men and Women
Bergstrom H; Frankling MH; Klasson C; Sandblom AL; Diczfalusy U; Bjorkhem-Bergman L
Article: BRITISH JOURNAL OF PHARMACOLOGY. 2021;178(16):3294-3308
Early or deferred initiation of efavirenz during rifampicin-based TB therapy has no significant effect on CYP3A induction in TB-HIV infected patients
Aklillu E; Zumla A; Habtewold A; Amogne W; Makonnen E; Yimer G; Burhenne J; Diczfalusy U
Article: JOURNAL OF PERSONALIZED MEDICINE. 2021;11(6):457
Evaluation of 1β-Hydroxylation of Deoxycholic Acid as a Non-Invasive Urinary Biomarker of CYP3A Activity in the Assessment of Inhibition-Based Drug-Drug Interaction in Healthy Volunteers
Li X-Q; Thelingwani RS; Bertilsson L; Diczfalusy U; Andersson TB; Masimirembwa C
Article: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2019;190:115-125
First international descriptive and interventional survey for cholesterol and non-cholesterol sterol determination by gas- and liquid-chromatography-Urgent need for harmonisation of analytical methods
Luetjohann D; Bjorkhem I; Friedrichs S; Kerksiek A; Lovgren-Sandblom A; Geilenkeuser W-J; Ahrends R; Andrade I; Ansorena D; Astiasaran I; Baila-Rueda L; Barriuso B; Becker S; Bretillon L; Browne RW; Caccia C; Ceglarek UH; Cenarro A; Crick PJ; Fauler G; Garcia-Llatas G; Gray R; Griffiths WJ; Gylling H; Harding S; Helmschrodt C; Iuliano L; Janssen H-G; Jones P; Kaipiainen L; Kannenberg F; Jesus Lagarda M; Leoni V; Lottenberg AM; MacKay DS; Matysik S; McDonald J; Menendez-Carreno M; Myrie SB; Nunes VS; Ostlund RE; Polisecki E; Ramos F; Rideout TC; Schaefer EJ; Schmitz G; Wang Y; Zerbinati C; Diczfalusy U; Schoett H-F
Article: AAPS JOURNAL. 2019;21(4):58
Effect of Grapefruit Juice Intake on Serum Level of the Endogenous CYP3A4 Metabolite 4-Hydroxycholesterolan Interaction Study in Healthy Volunteers
Gjestad C; Hole K; Haslemo T; Diczfalusy U; Molden E
Article: BIOCHIMIE. 2018;153:26-32
International descriptive and interventional survey for oxycholesterol determination by gas- and liquid-chromatographic methods
Luetjohann D; Bjorkhem I; Friedrichs S; Kerksiek A; Geilenkeuser W-J; Lovgren-Sandblom A; Ansorena D; Astiasaran I; Baila-Rueda L; Barriuso B; Bretillon L; Browne RW; Caccia C; Cenarro A; Crick PJ; Fauler G; Garcia-Llatas G; Griffiths WJ; Iuliano L; Jesus Lagarda M; Leoni V; Lottenberg AM; Matysik S; McDonald J; Rideout TC; Schmitz G; Nunes VS; Wang Y; Zerbinati C; Diczfalusy U; Schoett H-F
Article: BMC PHARMACOLOGY & TOXICOLOGY. 2018;19(1):33
Inflammation down-regulates CYP3A4-catalysed drug metabolism in hemodialysis patients
Molanaei H; Qureshi AR; Heimburger O; Lindholm B; Diczfalusy U; Anderstam B; Bertilsson L; Stenvinkel P
Article: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 2016;82(6):1539-1549
Comparative performance of oral midazolam clearance and plasma 4-hydroxycholesterol to explain interindividual variability in tacrolimus clearance
Vanhove T; de Jonge H; de Loor H; Annaert P; Diczfalusy U; Kuypers DRJ
Article: DRUG METABOLISM AND DISPOSITION. 2016;44(9):1480-1489
CYP3A Specifically Catalyzes 1β-Hydroxylation of Deoxycholic Acid: Characterization and Enzymatic Synthesis of a Potential Novel Urinary Biomarker for CYP3A Activity
Hayes MA; Li X-Q; Gronberg G; Diczfalusy U; Andersson TB
Article: MEDICINE. 2016;95(34):e4631
Prevalence and risk factors for efavirenz-based antiretroviral treatment-associated severe vitamin D deficiency: A prospective cohort study
Nylen H; Habtewold A; Makonnen E; Yimer G; Bertilsson L; Burhenne J; Diczfalusy U; Aklillu E
Article: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 2016;118(6):499-502
Effect of Statin Treatment on Plasma 4β-Hydroxycholesterol Concentrations
Bjorkhem-Bergman L; Nylen H; Eriksson M; Parini P; Diczfalusy U
Article: PHARMACOLOGY RESEARCH & PERSPECTIVES. 2015;3(6):e00192
miRNA-27b levels are associated with CYP3A activity in vitro and in vivo
Ekstrom L; Skilving I; Ovesjo M-L; Aklillu E; Nylen H; Rane A; Diczfalusy U; Bjorkhem-Bergman L
Article: PLOS ONE. 2015;10(4):e0121984
No Impact of Vitamin D on the CYP3A Biomarker 4β-Hydroxycholesterol in Patients with Abnormal Glucose Regulation
Mannheimer B; Wagner H; Otstenson C-G; Diczfalusy U
Article: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 2014;69(12):3311-3319
Pharmacokinetic and pharmacogenomic modelling of the CYP3A activity marker 4β-hydroxycholesterol during efavirenz treatment and efavirenz/rifampicin co-treatment
Ngaimisi E; Minzi O; Mugusi S; Sasi P; Riedel K-D; Suda A; Ueda N; Bakari M; Janabi M; Mugusi F; Bertilsson L; Burhenne J; Aklillu E; Diczfalusy U
Article: MICROCIRCULATION. 2014;21(7):587-592
Immediate Effect of Passive Smoking on Microcirculatory Flow
Henriksson P; Lu Q; Diczfalusy U; Freyschuss A
Article: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 2014;115(4):366-371
Plasma Levels of 25-Hydroxyvitamin D₃ and In Vivo Markers of Cytochrome P450 3A Activity in Swedes and Koreans: Effects of a Genetic Polymorphism and Oral Contraceptives
Nylen H; Bjorkhem-Bergman L; Ekstrom L; Roh H-K; Bertilsson L; Eliasson E; Lindh JD; Diczfalusy U
Article: DRUG METABOLISM AND PHARMACOKINETICS. 2014;29(4):352-355
Quinine Compared to 4β-Hydroxycholesterol and Midazolam as Markers for CYP3A Induction by Rifampicin
Bjorkhem-Bergman L; Backstrom T; Nylen H; Ronquist-Nii Y; Bredberg E; Andersson TB; Bertilsson L; Diczfalusy U
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Corrigendum: JOURNAL OF PERSONALIZED MEDICINE. 2026;16(7):382
Correction: Li et al. Evaluation of 1β-Hydroxylation of Deoxycholic Acid as a Non-Invasive Urinary Biomarker of CYP3A Activity in the Assessment of Inhibition-Based Drug-Drug Interaction in Healthy Volunteers. J. Pers. Med. 2021, 11, 457.
Li X-Q; Thelingwani RS; Bertilsson L; Diczfalusy U; Andersson TB; Masimirembwa C
Book chapter: MAMMALIAN STEROLS. 2020;p. 41-79
Side-Chain Oxidized Oxysterols in Health and Disease
Björkhem I; Diczfalusy U
Editorial: BIOANALYSIS. 2017;9(9):675-681
Feedback from the EBF - Focus Workshop: Bringing Assay Validation and Analysis of Biomarkers into Practice
Timmerman P; Fjording MS; Allinson J; Arfvidsson C; Barroso B; Diczfalusy U; Freeman A; Hickford E; Kandousi H; Katugampola S; Kunz U; Nelson R; Smeraglia J
Editorial: AAPS JOURNAL. 2016;18(5):1056-1066
Recommendations on the Development of a Bioanalytical Assay for 4β-Hydroxycholesterol, an Emerging Endogenous Biomarker of CYP3A Activity
Aubry A-F; Dean B; Diczfalusy U; Goodenough A; Iffland A; McLeod J; Weng N; Yang Z
Review: BIOCHIMIE. 2013;95(3):455-460
On the formation and possible biological role of 25-hydroxycholesterol
Diczfalusy U
Editorial: JOURNAL OF LIPID RESEARCH. 2011;52(8):1447-1449
Still another activity by the highly promiscuous enzyme CYP3A4: 25-hydroxylation of cholesterol
Diczfalusy U; Bjorkhem I
Letter: NATURE IMMUNOLOGY. 2011;12(7):577
Detecting oxysterols in the human circulation
Bjorkhem I; Diczfalusy U; Olsson T; Russell DW; McDonald JG; Wang Y; Griffiths WJ
Review: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 2011;71(2):183-189
4β-hydroxycholesterol, an endogenous marker of CYP3A4/5 activity in humans
Diczfalusy U; Nylen H; Elander P; Bertilsson L
Book chapter: BIOMARKERS FOR ANTIOXIDANT DEFENSE AND OXIDATIVE DAMAGE: PRINCIPLES AND PRACTICAL APPLICATIONS. 2010;p. 99-115
Oxysterols: Potential Biomarkers of Oxidative Stress
Iuliano L; Diczfalusy U
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2006;7(3):562
Effects of high-dosage itraconazole treatment on synthesis, transport and metabolism of cholesterol in men
Schneider B; Plat J; Gerdsen R; Diczfalusy U; Björkhem I; Neuvonen PJ; Bieber T; Von Bergmann K; L tjohann D
Published conference paper: ACTA NEUROLOGICA SCANDINAVICA, SUPPLEMENT. 2006;114:43-49
Oxysterols and Alzheimer's disease
Bjorkhem I; Heverin M; Leoni V; Meaney S; Diczfalusy U
Book chapter: BILE ACID BIOLOGY AND ITS THERAPEUTIC IMPLICATIONS: FALK SYMPOSIUM. 2005;p. 37-40
Role of CYP3A4 as a cholesterol and bile acid metabolizing enzyme
Bodin K; Diczfalusy U
Book chapter: BILE ACID BIOLOGY AND ITS THERAPEUTIC IMPLICATIONS: FALK SYMPOSIUM. 2005;p. 219-224
Comprehensive study of the effects of rifampicin and ursodeoxycholic acid on genes and proteins involved in regulation, transport and detoxification of biliary compounds in gallstone patients
Marschall H-U; Wagner M; Zollner G; Fickert P; Gumhold J; Silbert D; Diczfalusy U; Benthin L; Grundström R; Gustafsson U; Sahlin S; Einarsson C; Trauner M
Editorial: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2004;24(12):2209-2210
24(S),25-epoxycholesterol - A potential friend
Bjorkhem I; Diczfalusy U
Meeting abstract: JOURNAL OF HEPATOLOGY. 2004;40:93
Comprehensive study of the effects of rifampicin and ursodeoxycholic acid on genes and proteins involved in regulation, transport and detoxification of biliary compounds in gallstone patients
Marschall HU; Wagner M; Zollner G; Fickert P; Gumholdt J; Silbert D; Diczfalusy U; Benthin L; Grundstrom R; Sahlin S; Einarsson C; Trauner M
Review: RECOMBINANT PROTEIN EXPRESSION: PROKARYOTIC HOSTS AND CELL-FREE SYSTEMS. 2003;364:24-37
Quantitation of receptor Ligands by mass Spectrometry
Lund EG; Diczfalusy U
Editorial: EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY. 2002;104(7):435-439
Analysis of cholesterol oxidation products in plasma, tissues and food
Bodin K; Diczfalusy U
Review: CURRENT OPINION IN LIPIDOLOGY. 2002;13(3):247-253
Oxysterols in human circulation: which role do they have?
Björkhem I; Meaney S; Diczfalusy U
Published conference paper: CELL BIOCHEMISTRY AND BIOPHYSICS. 2000;32:317-324
Acyl-CoA thioesterases belong to a novel gene family of peroxisome proliferator-regulated enzymes involved in lipid metabolism
Hunt MC; Lindquist PJG; Nousiainen S; Huttunen M; Orii K; Svensson TLT; Aoyama T; Hashimoto T; Diczfalusy U; Alexson SEH
Meeting abstract: ATHEROSCLEROSIS. 1999;144:121
The lung is the major source of 27-oxygenated cholesterol in the human circulation
Babiker A; Björkhem I; Diczfalusy U
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